Clinical Trials

NCT04253964 | RECRUITING | PHASE2

105 participants

Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-07-01

Completion:

2027-09-01

Conditions

• Nonsmall Cell Lung Cancer
• Performance Status

Interventions

• DRUG
• OTHER

No Results Yet

NCT04242264 | COMPLETED | PHASE2

69 participants

Phase 2 Shigella Vaccine and Challenge

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-10-12

Completion:

2024-03-11

Conditions

• Immunisation
• Shigella Infection

Interventions

• OTHER
• BIOLOGICAL

Results Available

NCT04236882 | ACTIVE_NOT_RECRUITING | NA

28 participants

Sleep and Physical Activity Intervention for Increasing Physical Activity in Overweight or Obese and Sedentary African Americans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-10-04

Completion:

2030-04-30

Conditions

• Behavioral Disorder
• Endocrine System Disorder

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04224493 | ACTIVE_NOT_RECRUITING | PHASE3

599 participants

A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-06-11

Completion:

2027-02-13

Conditions

• Relapsed/Refractory Follicular Lymphoma
• Follicular Lymphoma
• Refractory Follicular Lymphoma

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT04219280 | ACTIVE_NOT_RECRUITING | PHASE4

100 participants

Evaluating Treatment of ADHD in Children With Down Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-10-02

Completion:

2026-08-31

Conditions

• Down Syndrome
• ADHD

Interventions

• DRUG

No Results Yet

NCT04210687 | ACTIVE_NOT_RECRUITING | NA

90 participants

Trapeziectomy vs. Trapeziometacarpal Limited Excision for Thumb Base Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-03-09

Completion:

2026-12-01

Conditions

• Thumb Osteoarthritis

Interventions

• PROCEDURE

No Results Yet

NCT04197934 | ACTIVE_NOT_RECRUITING | PHASE1

56 participants

WSD0922-FU for Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-12-20

Completion:

2022-10-30

Conditions

• Anaplastic Astrocytoma, IDH-Wildtype
• Glioblastoma, IDH-Wildtype
• Metastatic Lung Non-Small Cell Carcinoma
• Metastatic Malignant Neoplasm in the Central Nervous System
• Stage IV Lung Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04171622 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

Lenvatinib and Pembrolizumab for the Treatment of Stage IVB Locally Advanced and Unresectable or Stage IVC Metastatic Anaplastic Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-11-04

Completion:

2027-08-31

Conditions

• Metastatic Thyroid Gland Carcinoma
• Poorly Differentiated Thyroid Gland Carcinoma
• Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8
• Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v8
• Thyroid Gland Squamous Cell Carcinoma
• Unresectable Thyroid Gland Carcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04118998 | ACTIVE_NOT_RECRUITING | NA

86 participants

Progressive Abduction Loading Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-08-27

Completion:

2026-07-07

Conditions

• Stroke, Acute

Interventions

• BEHAVIORAL

No Results Yet

NCT04108741 | TERMINATED | NA

39 participants

Augmented Reality Treadmill Training in Patients With Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-09-15

Completion:

2025-06-10

Conditions

• Parkinson Disease
• Fall

Interventions

• DEVICE

No Results Yet

NCT04107311 | ACTIVE_NOT_RECRUITING

120 participants

Prospective Analysis of Intestinal Microbiome and Autoimmune Panels as Predictors of Toxicity in ImmunOncology Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2019-09-05

Completion:

2027-03-05

Conditions

• Solid Tumor

No Results Yet

NCT04106973 | TERMINATED

12 participants

Mesothelioma Early Detection by VOCs

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2019-06-05

Completion:

2022-01-01

Conditions

• Pleural Mesothelioma
• Asbestos Exposure
• Pleural Plaque

No Results Yet

NCT04072211 | COMPLETED | PHASE4

641 participants

Demonstration Project on Health Care Worker Protection Against Hepatitis B in Kalulushi District

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-11-25

Completion:

2020-08-30

Conditions

• Hepatitis B Virus
• Health Care Associated Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT04044365 | ACTIVE_NOT_RECRUITING

139 participants

Pediatric cGVHD Symptom Scale

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2019-10-02

Completion:

2026-12-31

Conditions

• Graft vs Host Disease

No Results Yet

NCT04026516 | COMPLETED | NA

29 participants

CAVA: Dizziness Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-07-01

Completion:

2025-10-31

Conditions

• Meniere's Disease
• Benign Paroxysmal Positional Vertigo
• Recurrent Vestibulopathy
• Vestibular Migraine

Interventions

• DEVICE

No Results Yet

NCT03959800 | RECRUITING

1600 participants

Molecular Basis of Pediatric Liver Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2015-06-22

Completion:

2030-06-30

Conditions

• Childhood Liver Cancer
• Liver Malignant Tumors
• Embryonal Sarcoma of Liver (Disorder)
• Hepatoblastoma
• Hepatocellular Carcinoma
• Rhabdoid Tumor of Liver

No Results Yet

NCT03946878 | ACTIVE_NOT_RECRUITING | PHASE2

32 participants

Venetoclax and Acalabrutinib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-08-13

Completion:

2028-02-08

Conditions

• Blastoid Variant Mantle Cell Lymphoma
• CCND1 Protein Overexpression
• CD20 Positive
• CD5 Positive
• FCER2 Negative
• Pleomorphic Variant Mantle Cell Lymphoma
• Recurrent Mantle Cell Lymphoma
• Refractory Mantle Cell Lymphoma
• t(11;14)(q13;q32)

Interventions

• DRUG

No Results Yet

NCT03931694 | COMPLETED

113 participants

E-health Tool for Management of Chronic Pain Patients.

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2019-02-06

Completion:

2020-06-04

Conditions

• Chronic Pain

Interventions

• DEVICE

No Results Yet

NCT03884075 | RECRUITING | PHASE2

104 participants

Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-07-24

Completion:

2027-09-03

Conditions

• Non-Alcoholic Steatohepatitis
• Non-Alcoholic Fatty Liver Disease

Interventions

• DRUG

No Results Yet

NCT03859128 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

427 participants

Toripalimab or Placebo as Adjuvant Therapy in Hepatocellular Carcinoma After Radical Resection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-03-05

Completion:

2026-12-31

Conditions

• Hepatocellular Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT03851614 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-04-08

Completion:

2027-01-01

Conditions

• Mismatch Repair Proficient Colorectal Cancer
• Pancreatic Adenocarcinoma
• Leiomyosarcoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03843385 | ACTIVE_NOT_RECRUITING | PHASE3

84 participants

Transfer of FRozen Encapsulated Multidonor Stool Filtrate for Active Ulcerative COlitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-01-31

Completion:

2026-08-31

Conditions

• Ulcerative Colitis
• Inflammatory Bowel Diseases

Interventions

• DRUG

No Results Yet

NCT03838939 | COMPLETED | NA

120 participants

Biotherapies and Therapeutic Education in Chronic Inflammatory Rheumatism

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-01-21

Completion:

2021-12-10

Conditions

• Rheumatoid Arthritis
• Spondyloarthritis

Interventions

• OTHER

No Results Yet

NCT03831386 | ACTIVE_NOT_RECRUITING | NA

200 participants

Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-01-31

Completion:

2026-12-31

Conditions

• Pleural Effusion

Interventions

• PROCEDURE

No Results Yet

NCT03824652 | RECRUITING | PHASE2

50 participants

WALNUTS for POWER: Polyphenols, Omega-3 Fatty Acids, Weight Loss, and EneRgy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-04-22

Completion:

2026-12-31

Conditions

• Prostate Cancer

Interventions

• OTHER

No Results Yet

NCT03744845 | COMPLETED | NA

40 participants

The Use of Virtual Reality to Reduce Anxiety and Pain in Perioperative Settings

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2018-12-10

Completion:

2024-05-15

Conditions

• Perioperative Pain
• Perioperative Anxiety

Interventions

• OTHER

No Results Yet

NCT03744390 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

IDH2 (AG 221) Inhibitor in Patients With IDH2 Mutated Myelodysplastic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-04-02

Completion:

2023-02-18

Conditions

• Myelodysplastic Syndromes
• Leukemia Acute Myeloid

Interventions

• DRUG

No Results Yet

NCT03741673 | ACTIVE_NOT_RECRUITING | PHASE3

180 participants

Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2018-11-08

Completion:

2027-01-31

Conditions

• Malignant Neoplasm
• Metastatic Malignant Neoplasm in the Brain

Interventions

• OTHER
• RADIATION

No Results Yet

NCT03691922 | COMPLETED | NA

62 participants

Erector Spinae Block Versus Shoulder Periarticular Anesthetic Infiltration for Arthroscopic Shoulder Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-07-06

Completion:

2020-02-01

Conditions

• Arthroscopic Shoulder Surgery

Interventions

• PROCEDURE

No Results Yet

NCT03575169 | COMPLETED

26 participants

The Use of Bispectral Index Monitoring to Assess Depth of Sedation in Patients With Traumatic Brain Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2019-07-01

Completion:

2022-12-31

Conditions

• Traumatic Brain Injury

Interventions

• DEVICE

Results Available

NCT03542409 | COMPLETED | EARLY_PHASE1

53 participants

Safety and Feasibility of Preoperative and Intraoperative Image-Guided Resection of Gliomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2017-02-15

Completion:

2021-10-28

Conditions

• Brain Tumor Adult

Interventions

• DEVICE

No Results Yet

NCT03503409 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

IDH1 (AG 120) Inhibitor in Patients With IDH1 Mutated Myelodysplastic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-05-14

Completion:

2027-04-02

Conditions

• Myelodysplastic Syndromes
• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT03453112 | COMPLETED | PHASE3

494 participants

Foster 100/6 mg NEXThaler Versus Foster 100/6mg Pressurized Metered-dose Inhaler (pMDI) in Patients With Controlled Asthma.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2017-10-09

Completion:

2021-12-28

Conditions

• Asthma

Interventions

• DRUG

Results Available

NCT03441061 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2018-02-15

Completion:

2027-02-28

Conditions

• Acute Lymphoblastic Leukemia
• B Acute Lymphoblastic Leukemia
• Recurrent B Acute Lymphoblastic Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT03437135 | COMPLETED

172 participants

Screening and Characterization of Hearing Disorders in Diabetic Persons

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2015-12-01

Completion:

2020-12-14

Conditions

• Diabetes
• Hearing Problems

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03418818 | ACTIVE_NOT_RECRUITING | NA

70 participants

FAZA PET/MRI Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2018-03-27

Completion:

2028-10-31

Conditions

• Sarcoma

Interventions

• DRUG

No Results Yet

NCT03406611 | RECRUITING | PHASE1/PHASE2

39 participants

Pegtibatinase as a Treatment for Patients With Classical Homocystinuria (HCU) (Also Known as the COMPOSE Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-01-22

Completion:

2027-07-31

Conditions

• Homocystinuria

Interventions

• DRUG

No Results Yet

NCT03368742 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

12 participants

Microdystrophin Gene Transfer Study in Adolescents and Children With DMD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2017-12-06

Completion:

2026-10-15

Conditions

• Duchenne Muscular Dystrophy

Interventions

• GENETIC

No Results Yet

NCT03346369 | COMPLETED | PHASE3

54 participants

Lanthanum Carbonate (Fosrenol®) to Reduce Oxalate Excretion in Patients With Secondary Hyperoxaluria and Nephrolithiasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2017-08-18

Completion:

2024-08-10

Conditions

• Secondary Hyperoxaluria
• Nephrolithiasis

Interventions

• DRUG

No Results Yet

NCT03274375 | COMPLETED | PHASE2

20 participants

Immunoadsorption Therapy in Managing NMDAR Antibodies Encephalitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-06-23

Completion:

2023-10-26

Conditions

• Anti-NMDAR Encephalitis

Interventions

• DRUG

No Results Yet