Clinical Trials

NCT04731688 | COMPLETED | NA

100 participants

A Weight Maintenance Program Promoting Fat Loss in Pregnancy in Women With Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-03-10
Completion:: 2025-11-24

Conditions

Gestational Weight Gain
Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT04698031 | ACTIVE_NOT_RECRUITING | PHASE4

134 participants

Efficacy of Clopidogrel on Incidence of Silent Brain Infarction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-03-30
Completion:: 2026-05-01

Conditions

Silent Brain Infarction

Interventions

DRUG

No Results Yet

NCT04692701 | COMPLETED | NA

12 participants

Pulvinar Stimulation in Epilepsy: a Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-01-15
Completion:: 2023-10-23

Conditions

Epilepsy

Interventions

DEVICE

No Results Yet

NCT04692337 | RECRUITING | NA

100 participants

Ommaya Reservoir Placement for Brain Tumor Biomarker Access

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-01-15
Completion:: 2027-02-28

Conditions

Brain Tumor

Interventions

PROCEDURE

No Results Yet

NCT04680468 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

Study of Belantamab Mafodotin as Pre- and Post-autologous Stem Cell Transplant and Maintenance for Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-06-02
Completion:: 2026-11-01

Conditions

Myeloma

Interventions

DRUG

No Results Yet

NCT04679714 | WITHDRAWN | NA

0 participants

EXPLORE FMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Functional Mitral Regurgitation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-04-30
Completion:: 2022-03-31

Conditions

Functional Mitral Regurgitation

Interventions

DEVICE

No Results Yet

NCT04679662 | WITHDRAWN | NA

0 participants

EXPLORE DMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-04-30
Completion:: 2022-03-31

Conditions

Degenerative Mitral Valve Disease

Interventions

DEVICE

No Results Yet

NCT04650074 | COMPLETED | PHASE2/PHASE3

31 participants

Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-11-05
Completion:: 2024-01-12

Conditions

Neuropathic Pain
Complex Regional Pain Syndrome Type 1

Interventions

DRUG

No Results Yet

NCT04634916 | RECRUITING | NA

220 participants

Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-03-26
Completion:: 2027-06-30

Conditions

Kidney Disease, End-Stage
End-stage Renal Disease
Arteriovenous Fistula

Interventions

DEVICE

No Results Yet

NCT04623801 | ACTIVE_NOT_RECRUITING | PHASE2

10 participants

Laser Ablation of Papillary Thyroid Microcarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-10-19
Completion:: 2026-10-31

Conditions

Papillary Thyroid Microcarcinoma
Thyroid
Thyroid Cancer

Interventions

PROCEDURE

No Results Yet

NCT04616560 | RECRUITING | PHASE1/PHASE2

55 participants

Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-03-08
Completion:: 2027-12-31

Conditions

Desmoplastic Small Round Cell Tumor
Osteosarcoma
Recurrent Desmoplastic Small Round Cell Tumor
Recurrent Kidney Wilms Tumor
Recurrent Osteosarcoma
Refractory Desmoplastic Small Round Cell Tumor
Refractory Wilms Tumor
Wilms Tumor

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT04609046 | RECRUITING | PHASE1

47 participants

Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-05-24
Completion:: 2027-04-01

Conditions

Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT04608110 | RECRUITING | PHASE1

59 participants

A Phase 1 Trial of ASTX030 in Patients With Myelodysplastic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-10-30
Completion:: 2027-12-31

Conditions

Myelodysplastic Syndrome (MDS)

Interventions

DRUG

No Results Yet

NCT04606095 | ACTIVE_NOT_RECRUITING | NA

150 participants

Explosive Synchronization of Brain Network Activity in Chronic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-11-13
Completion:: 2026-12-20

Conditions

Fibromyalgia
Healthy Volunteers

Interventions

DIAGNOSTIC_TEST
DEVICE

No Results Yet

NCT04594187 | RECRUITING | PHASE2

168 participants

Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-08-07
Completion:: 2027-12-31

Conditions

Melanoma

Interventions

OTHER
RADIATION

No Results Yet

NCT04585958 | RECRUITING | PHASE1

55 participants

Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-05-21
Completion:: 2026-12-31

Conditions

Metastatic Malignant Solid Neoplasm
Platinum-Resistant Ovarian High Grade Serous Adenocarcinoma
Unresectable Malignant Solid Neoplasm

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT04585750 | RECRUITING | PHASE1/PHASE2

300 participants

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-10-29
Completion:: 2026-08-15

Conditions

Advanced Solid Tumor
Advanced Malignant Neoplasm
Metastatic Cancer
Metastatic Solid Tumor
Lung Cancer
Ovarian Cancer
Endometrial Cancer
Prostate Cancer
Colorectal Cancer
Breast Cancer
Other Cancer
Locally Advanced
Head and Neck Cancer
Gall Bladder Cancer
Small Cell Lung Cancer
Small Cell Lung Cancer ( SCLC )
Small Cell Lung Carcinoma
NSCLC
NSCLC (Non-small Cell Lung Cancer)
SCLC
Non-Small Cell Lung Carcinoma
Triple Negative Breast Cancer
TNBC
HER2+ Breast Cancer
Non-Small Cell Lung Cancer
ER/PR Positive Breast Cancer
HER2- Breast Cancer
HER2-positive Breast Cancer
HER2-negative Breast Cancer
ER/PR(+), Her2(-) Breast Cancer

Interventions

DRUG

No Results Yet

NCT04561986 | ACTIVE_NOT_RECRUITING | PHASE3

50 participants

TocIlizumab in Late/Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-02-01
Completion:: 2028-06-30

Conditions

Antibody-mediated Rejection

Interventions

DRUG

No Results Yet

NCT04558164 | ACTIVE_NOT_RECRUITING | NA

70 participants

Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-01-26
Completion:: 2026-11-30

Conditions

Cognitive Dysfunction
Memory Disorders in Old Age

Interventions

DEVICE

No Results Yet

NCT04552704 | TERMINATED | PHASE1/PHASE2

3 participants

CD24Fc for the Treatment of Immune Related Adverse Events in Patients With Advanced Solid Tumors, TIRAEC Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-10-30
Completion:: 2021-02-03

Conditions

Advanced Malignant Solid Neoplasm

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04545736 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

55 participants

Oral Metformin for Treatment of ABCA4 Retinopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-11-23
Completion:: 2028-02-02

Conditions

ABCA4 Retinopathy
Stargardt Disease
Retinal Dystrophy
Retinal Degeneration

Interventions

DRUG

No Results Yet

NCT04525989 | RECRUITING | NA

254 participants

Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-04-20
Completion:: 2028-03-31

Conditions

Rectal Cancer

Interventions

RADIATION

No Results Yet

NCT04519879 | SUSPENDED | PHASE2

133 participants

White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-05-10
Completion:: 2026-03-31

Conditions

Prostate Adenocarcinoma
PSA Failure
PSA Progression
Recurrent Prostate Carcinoma
Stage I Prostate Cancer AJCC v8
Stage IIA Prostate Cancer AJCC v8
Stage IIB Prostate Cancer AJCC v8
Stage IIC Prostate Cancer AJCC v8
Stage IIIA Prostate Cancer AJCC v8
Stage IIIC Prostate Cancer AJCC v8

Interventions

OTHER
DRUG

No Results Yet

NCT04517487 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

30 participants

Vaginal Microbiome Transplantation for Recurrent Bacterial Vaginosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-08-20
Completion:: 2026-12-31

Conditions

Bacterial Vaginoses

Interventions

BIOLOGICAL

No Results Yet

NCT04488250 | ACTIVE_NOT_RECRUITING | NA

30 participants

Robot-Assisted Rehabilitation After HIV-Associated Stroke: Botswana

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-10-01
Completion:: 2026-07-30

Conditions

HIV/AIDS
Stroke

Interventions

OTHER

No Results Yet

NCT04481633 | COMPLETED | NA

547 participants

Efficacy of Pre-exposure Treatment With Hydroxy-Chloroquine on the Risk and Severity of COVID-19 Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-09-09
Completion:: 2022-12-06

Conditions

COVID-19

Interventions

DIAGNOSTIC_TEST
OTHER

Results Available

NCT04469075 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-07-09
Completion:: 2027-07-31

Conditions

Glioblastoma
Recurrent Glioblastoma
Skin Toxicity

Interventions

DRUG

No Results Yet

NCT04449549 | RECRUITING | PHASE2

82 participants

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-08-24
Completion:: 2027-04-02

Conditions

Neoplasms

Interventions

DRUG

No Results Yet

NCT04426214 | TERMINATED | NA

33 participants

Neuromodulation and Cognitive Training for Substance Use Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-07-16
Completion:: 2026-06-20

Conditions

Stimulant Use
Alcohol Use Disorder

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT04415944 | COMPLETED | PHASE2

10 participants

Trial Evaluating Feasibility and Quality of Life of Second Look Laparoscopy With Hyperthermic Intraperitoneal Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-05-20
Completion:: 2025-09-19

Conditions

Ovarian Epithelial Cancer Stage I
Ovarian Epithelial Cancer Stage II
Ovarian Epithelial Cancer Stage III
Stage I Fallopian Tube Cancer
Stage II Fallopian Tube Cancer
Stage III Fallopian Tube Cancer
Peritoneal Carcinoma

Interventions

PROCEDURE
DRUG
OTHER

Results Available

NCT04403035 | WITHDRAWN

0 participants

Comparison of the ID NOW and Accula Point-of-Care Assays for Detection of COVID-19

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-05-10
Completion:: 2020-07-01

Conditions

Covid-19

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04402788 | RECRUITING | PHASE2/PHASE3

138 participants

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-01-07
Completion:: 2027-04-30

Conditions

Extensive Stage Lung Small Cell Carcinoma

Interventions

PROCEDURE
RADIATION
DRUG

No Results Yet

NCT04346784 | COMPLETED | NA

110 participants

Cognitive Control Emotion Training to Prevent Major Depression in Youth At-Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-10-15
Completion:: 2025-04-24

Conditions

Depressive Symptoms
Remited Major Depressive Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT04339764 | RECRUITING | PHASE1/PHASE2

20 participants

Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-09-23
Completion:: 2029-05-31

Conditions

Dry Age-Related Macular Degeneration
Geographic Atrophy

Interventions

DRUG

No Results Yet

NCT04321200 | COMPLETED

166 participants

PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-11-01
Completion:: 2025-10-27

Conditions

Pediatric ALL
Infant Development
Neurodevelopmental Disorders

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT04289571 | RECRUITING | PHASE1

165 participants

Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-07-25
Completion:: 2030-12-31

Conditions

Cone-Rod Degeneration
Rod-Cone Degeneration

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04288635 | RECRUITING

55 participants

Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-07-09
Completion:: 2027-07-09

Conditions

Septic Shock
Multiple Organ Failure

Interventions

BIOLOGICAL

No Results Yet

NCT04253964 | RECRUITING | PHASE2

105 participants

Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-07-01
Completion:: 2027-09-01

Conditions

Nonsmall Cell Lung Cancer
Performance Status

Interventions

DRUG
OTHER

No Results Yet

NCT04242264 | COMPLETED | PHASE2

69 participants

Phase 2 Shigella Vaccine and Challenge

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-10-12
Completion:: 2024-03-11

Conditions

Immunisation
Shigella Infection

Interventions

OTHER
BIOLOGICAL

Results Available

NCT04236882 | ACTIVE_NOT_RECRUITING | NA

28 participants

Sleep and Physical Activity Intervention for Increasing Physical Activity in Overweight or Obese and Sedentary African Americans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-10-04
Completion:: 2030-04-30

Conditions

Behavioral Disorder
Endocrine System Disorder

Interventions

OTHER
BEHAVIORAL

No Results Yet