Clinical Trials

NCT04731688 | COMPLETED | NA

100 participants

A Weight Maintenance Program Promoting Fat Loss in Pregnancy in Women With Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-03-10

Completion:

2025-11-24

Conditions

• Gestational Weight Gain
• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT04698031 | ACTIVE_NOT_RECRUITING | PHASE4

134 participants

Efficacy of Clopidogrel on Incidence of Silent Brain Infarction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-03-30

Completion:

2026-05-01

Conditions

• Silent Brain Infarction

Interventions

• DRUG

No Results Yet

NCT04692701 | COMPLETED | NA

12 participants

Pulvinar Stimulation in Epilepsy: a Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-01-15

Completion:

2023-10-23

Conditions

• Epilepsy

Interventions

• DEVICE

No Results Yet

NCT04692337 | RECRUITING | NA

100 participants

Ommaya Reservoir Placement for Brain Tumor Biomarker Access

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-01-15

Completion:

2027-02-28

Conditions

• Brain Tumor

Interventions

• PROCEDURE

No Results Yet

NCT04680468 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

Study of Belantamab Mafodotin as Pre- and Post-autologous Stem Cell Transplant and Maintenance for Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-06-02

Completion:

2026-11-01

Conditions

• Myeloma

Interventions

• DRUG

No Results Yet

NCT04679714 | WITHDRAWN | NA

0 participants

EXPLORE FMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Functional Mitral Regurgitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-04-30

Completion:

2022-03-31

Conditions

• Functional Mitral Regurgitation

Interventions

• DEVICE

No Results Yet

NCT04679662 | WITHDRAWN | NA

0 participants

EXPLORE DMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-04-30

Completion:

2022-03-31

Conditions

• Degenerative Mitral Valve Disease

Interventions

• DEVICE

No Results Yet

NCT04650074 | COMPLETED | PHASE2/PHASE3

31 participants

Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-11-05

Completion:

2024-01-12

Conditions

• Neuropathic Pain
• Complex Regional Pain Syndrome Type 1

Interventions

• DRUG

No Results Yet

NCT04634916 | RECRUITING | NA

220 participants

Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-03-26

Completion:

2027-06-30

Conditions

• Kidney Disease, End-Stage
• End-stage Renal Disease
• Arteriovenous Fistula

Interventions

• DEVICE

No Results Yet

NCT04623801 | ACTIVE_NOT_RECRUITING | PHASE2

10 participants

Laser Ablation of Papillary Thyroid Microcarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-10-19

Completion:

2026-10-31

Conditions

• Papillary Thyroid Microcarcinoma
• Thyroid
• Thyroid Cancer

Interventions

• PROCEDURE

No Results Yet

NCT04608110 | RECRUITING | PHASE1

59 participants

A Phase 1 Trial of ASTX030 in Patients With Myelodysplastic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-10-30

Completion:

2027-12-31

Conditions

• Myelodysplastic Syndrome (MDS)

Interventions

• DRUG

No Results Yet

NCT04606095 | ACTIVE_NOT_RECRUITING | NA

150 participants

Explosive Synchronization of Brain Network Activity in Chronic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-11-13

Completion:

2026-12-20

Conditions

• Fibromyalgia
• Healthy Volunteers

Interventions

• DIAGNOSTIC_TEST
• DEVICE

No Results Yet

NCT04594187 | RECRUITING | PHASE2

168 participants

Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-08-07

Completion:

2027-12-31

Conditions

• Melanoma

Interventions

• OTHER
• RADIATION

No Results Yet

NCT04585750 | RECRUITING | PHASE1/PHASE2

300 participants

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-10-29

Completion:

2026-08-15

Conditions

• Advanced Solid Tumor
• Advanced Malignant Neoplasm
• Metastatic Cancer
• Metastatic Solid Tumor
• Lung Cancer
• Ovarian Cancer
• Endometrial Cancer
• Prostate Cancer
• Colorectal Cancer
• Breast Cancer
• Other Cancer
• Locally Advanced
• Head and Neck Cancer
• Gall Bladder Cancer
• Small Cell Lung Cancer
• Small Cell Lung Cancer ( SCLC )
• Small Cell Lung Carcinoma
• NSCLC
• NSCLC (Non-small Cell Lung Cancer)
• SCLC
• Non-Small Cell Lung Carcinoma
• Triple Negative Breast Cancer
• TNBC
• HER2+ Breast Cancer
• Non-Small Cell Lung Cancer
• ER/PR Positive Breast Cancer
• HER2- Breast Cancer
• HER2-positive Breast Cancer
• HER2-negative Breast Cancer
• ER/PR(+), Her2(-) Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04561986 | ACTIVE_NOT_RECRUITING | PHASE3

50 participants

TocIlizumab in Late/Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-02-01

Completion:

2028-06-30

Conditions

• Antibody-mediated Rejection

Interventions

• DRUG

No Results Yet

NCT04558164 | ACTIVE_NOT_RECRUITING | NA

70 participants

Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-01-26

Completion:

2026-11-30

Conditions

• Cognitive Dysfunction
• Memory Disorders in Old Age

Interventions

• DEVICE

No Results Yet

NCT04552704 | TERMINATED | PHASE1/PHASE2

3 participants

CD24Fc for the Treatment of Immune Related Adverse Events in Patients With Advanced Solid Tumors, TIRAEC Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-10-30

Completion:

2021-02-03

Conditions

• Advanced Malignant Solid Neoplasm

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04525989 | RECRUITING | NA

254 participants

Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-04-20

Completion:

2028-03-31

Conditions

• Rectal Cancer

Interventions

• RADIATION

No Results Yet

NCT04519879 | SUSPENDED | PHASE2

133 participants

White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-05-10

Completion:

2026-03-31

Conditions

• Prostate Adenocarcinoma
• PSA Failure
• PSA Progression
• Recurrent Prostate Carcinoma
• Stage I Prostate Cancer AJCC v8
• Stage IIA Prostate Cancer AJCC v8
• Stage IIB Prostate Cancer AJCC v8
• Stage IIC Prostate Cancer AJCC v8
• Stage IIIA Prostate Cancer AJCC v8
• Stage IIIC Prostate Cancer AJCC v8

Interventions

• OTHER
• DRUG

No Results Yet

NCT04517487 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

30 participants

Vaginal Microbiome Transplantation for Recurrent Bacterial Vaginosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-08-20

Completion:

2026-12-31

Conditions

• Bacterial Vaginoses

Interventions

• BIOLOGICAL

No Results Yet

NCT04488250 | ACTIVE_NOT_RECRUITING | NA

30 participants

Robot-Assisted Rehabilitation After HIV-Associated Stroke: Botswana

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-10-01

Completion:

2026-07-30

Conditions

• HIV/AIDS
• Stroke

Interventions

• OTHER

No Results Yet

NCT04481633 | COMPLETED | NA

547 participants

Efficacy of Pre-exposure Treatment With Hydroxy-Chloroquine on the Risk and Severity of COVID-19 Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-09-09

Completion:

2022-12-06

Conditions

• COVID-19

Interventions

• DIAGNOSTIC_TEST
• OTHER

Results Available

NCT04469075 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-07-09

Completion:

2027-07-31

Conditions

• Glioblastoma
• Recurrent Glioblastoma
• Skin Toxicity

Interventions

• DRUG

No Results Yet

NCT04426214 | TERMINATED | NA

33 participants

Neuromodulation and Cognitive Training for Substance Use Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-07-16

Completion:

2026-06-20

Conditions

• Stimulant Use
• Alcohol Use Disorder

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04415944 | COMPLETED | PHASE2

10 participants

Trial Evaluating Feasibility and Quality of Life of Second Look Laparoscopy With Hyperthermic Intraperitoneal Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-05-20

Completion:

2025-09-19

Conditions

• Ovarian Epithelial Cancer Stage I
• Ovarian Epithelial Cancer Stage II
• Ovarian Epithelial Cancer Stage III
• Stage I Fallopian Tube Cancer
• Stage II Fallopian Tube Cancer
• Stage III Fallopian Tube Cancer
• Peritoneal Carcinoma

Interventions

• PROCEDURE
• DRUG
• OTHER

Results Available

NCT04403035 | WITHDRAWN

0 participants

Comparison of the ID NOW and Accula Point-of-Care Assays for Detection of COVID-19

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2020-05-10

Completion:

2020-07-01

Conditions

• Covid-19

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04346784 | COMPLETED | NA

110 participants

Cognitive Control Emotion Training to Prevent Major Depression in Youth At-Risk

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-10-15

Completion:

2025-04-24

Conditions

• Depressive Symptoms
• Remited Major Depressive Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04339764 | RECRUITING | PHASE1/PHASE2

20 participants

Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-09-23

Completion:

2029-05-31

Conditions

• Dry Age-Related Macular Degeneration
• Geographic Atrophy

Interventions

• DRUG

No Results Yet

NCT04321200 | COMPLETED

166 participants

PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2020-11-01

Completion:

2025-10-27

Conditions

• Pediatric ALL
• Infant Development
• Neurodevelopmental Disorders

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT04289571 | RECRUITING | PHASE1

165 participants

Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-07-25

Completion:

2030-12-31

Conditions

• Cone-Rod Degeneration
• Rod-Cone Degeneration

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04288635 | RECRUITING

55 participants

Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2020-07-09

Completion:

2027-07-09

Conditions

• Septic Shock
• Multiple Organ Failure

Interventions

• BIOLOGICAL

No Results Yet

NCT04253964 | RECRUITING | PHASE2

105 participants

Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-07-01

Completion:

2027-09-01

Conditions

• Nonsmall Cell Lung Cancer
• Performance Status

Interventions

• DRUG
• OTHER

No Results Yet

NCT04242264 | COMPLETED | PHASE2

69 participants

Phase 2 Shigella Vaccine and Challenge

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-10-12

Completion:

2024-03-11

Conditions

• Immunisation
• Shigella Infection

Interventions

• OTHER
• BIOLOGICAL

Results Available

NCT04236882 | ACTIVE_NOT_RECRUITING | NA

28 participants

Sleep and Physical Activity Intervention for Increasing Physical Activity in Overweight or Obese and Sedentary African Americans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-10-04

Completion:

2030-04-30

Conditions

• Behavioral Disorder
• Endocrine System Disorder

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04224493 | ACTIVE_NOT_RECRUITING | PHASE3

599 participants

A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-06-11

Completion:

2027-02-13

Conditions

• Relapsed/Refractory Follicular Lymphoma
• Follicular Lymphoma
• Refractory Follicular Lymphoma

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT04219280 | ACTIVE_NOT_RECRUITING | PHASE4

100 participants

Evaluating Treatment of ADHD in Children With Down Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-10-02

Completion:

2026-08-31

Conditions

• Down Syndrome
• ADHD

Interventions

• DRUG

No Results Yet

NCT04210687 | ACTIVE_NOT_RECRUITING | NA

90 participants

Trapeziectomy vs. Trapeziometacarpal Limited Excision for Thumb Base Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2020-03-09

Completion:

2026-12-01

Conditions

• Thumb Osteoarthritis

Interventions

• PROCEDURE

No Results Yet

NCT04197934 | ACTIVE_NOT_RECRUITING | PHASE1

56 participants

WSD0922-FU for Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2019-12-20

Completion:

2022-10-30

Conditions

• Anaplastic Astrocytoma, IDH-Wildtype
• Glioblastoma, IDH-Wildtype
• Metastatic Lung Non-Small Cell Carcinoma
• Metastatic Malignant Neoplasm in the Central Nervous System
• Stage IV Lung Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04171622 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

Lenvatinib and Pembrolizumab for the Treatment of Stage IVB Locally Advanced and Unresectable or Stage IVC Metastatic Anaplastic Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-11-04

Completion:

2027-08-31

Conditions

• Metastatic Thyroid Gland Carcinoma
• Poorly Differentiated Thyroid Gland Carcinoma
• Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8
• Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v8
• Thyroid Gland Squamous Cell Carcinoma
• Unresectable Thyroid Gland Carcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04118998 | ACTIVE_NOT_RECRUITING | NA

86 participants

Progressive Abduction Loading Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-08-27

Completion:

2026-07-07

Conditions

• Stroke, Acute

Interventions

• BEHAVIORAL

No Results Yet