Clinical Trials

NCT04782258 | RECRUITING | PHASE3

20 participants

A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2023-01-23

Completion:

2028-07-31

Conditions

• Autosomal Recessive Polycystic Kidney (ARPKD)

Interventions

• DRUG

No Results Yet

NCT04765111 | ACTIVE_NOT_RECRUITING | PHASE2

53 participants

Acalabrutinib and Rituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-06-30

Completion:

2028-08-30

Conditions

• Mantle Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04752722 | RECRUITING | PHASE1/PHASE2

350 participants

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-04-22

Completion:

2028-04-30

Conditions

• Superficial Bladder Cancer
• Non-muscle Invasive Bladder Cancer With Carcinoma in Situ
• Non-muscle Invasive Bladder Cancer

Interventions

• DRUG

No Results Yet

NCT04748913 | COMPLETED | NA

153 participants

Diagnostic Accuracy of Near Infrared Transillumination in Combination With a Dye in the Cavitation Detection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-11-09

Completion:

2023-11-09

Conditions

• Initial Proximal Caries

Interventions

• DEVICE
• DIAGNOSTIC_TEST

No Results Yet

NCT04747613 | ACTIVE_NOT_RECRUITING | PHASE3

208 participants

Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-07-27

Completion:

2027-10-18

Conditions

• Paroxysmal Nocturnal Hemoglobinuria

Interventions

• DRUG

No Results Yet

NCT04746911 | COMPLETED | PHASE2

10 participants

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-216)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-03-01

Completion:

2022-05-11

Conditions

• Psoriasis
• Plaque Psoriasis

Interventions

• DRUG

Results Available

NCT04734639 | COMPLETED | NA

17 participants

Appetite Response to Exercise- Versus Mixed (Exercise + Dietary Restriction)-Induced Energy Deficit in Adolescents With Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-04-24

Completion:

2021-06-30

Conditions

• Pediatric Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT04700150 | COMPLETED | NA

40 participants

Tai Chi in Spondyloarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2019-01-07

Completion:

2021-07-22

Conditions

• Spondyloarthritis

Interventions

• OTHER

No Results Yet

NCT04685408 | COMPLETED | NA

276 participants

A TargEted MAnageMent Intervention for Reducing Stroke Risk Factors in High Risk Ugandans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2022-05-13

Completion:

2024-03-06

Conditions

• Stroke

Interventions

• BEHAVIORAL

Results Available

NCT04664478 | COMPLETED

32 participants

Gene First Approach to Connective Tissue Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-07

Start Date:

2021-04-22

Completion:

2025-08-29

Conditions

• Abnormal Elastogenesis
• Vascular Diseases
• Connective Tissue Diseases

No Results Yet

NCT04641026 | ACTIVE_NOT_RECRUITING | NA

83 participants

Discovery of Biological Signatures for Cruciferous Vegetable Intake (Single Serving)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-02-22

Completion:

2025-12-15

Conditions

• Diet, Healthy

Interventions

• OTHER

No Results Yet

NCT04620382 | COMPLETED | EARLY_PHASE1

31 participants

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-11-09

Completion:

2025-07-01

Conditions

• Neurogenic Orthostatic Hypotension
• Autonomic Failure
• Pure Autonomic Failure
• Multiple System Atrophy
• Parkinson Disease

Interventions

• DRUG
• DEVICE

Results Available

NCT04573231 | RECRUITING | PHASE2

13 participants

Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-05-24

Completion:

2026-08-31

Conditions

• Breast Cancer
• HER2-negative Breast Cancer
• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04569708 | WITHDRAWN | NA

0 participants

Sleep Spindles and Memory in Rolandic Epilepsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-01-16

Completion:

2025-06-30

Conditions

• Rolandic Epilepsy
• Rolandic Epilepsy, Benign
• Centrotemporal Epilepsy
• Centrotemporal; EEG Spikes, Epilepsy of Childhood
• Epilepsy; Seizure
• Epilepsy

Interventions

• OTHER

No Results Yet

NCT04569162 | RECRUITING

100 participants

Rhizomelic Chondrodysplasia Punctata Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-07

Start Date:

2013-05-17

Completion:

2030-01-01

Conditions

• RCDP - Rhizomelic Chondrodysplasia Punctata
• RCDP1
• RCDP2
• RCDP3
• RCDP4
• RCDP5

No Results Yet

NCT04536480 | COMPLETED | NA

87 participants

Time Limited Eating in Adolescents With Type 2 Diabetes (KT2D)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2023-04-15

Completion:

2026-07-01

Conditions

• Pediatric Obesity
• Type 2 Diabetes
• Time Restricted Eating

Interventions

• BEHAVIORAL
• DEVICE

No Results Yet

NCT04535882 | COMPLETED

673 participants

Effectiveness of Serum Leucine-rich Alpha-2 Glycoprotein Levels on IBD

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-07

Start Date:

2020-10-01

Completion:

2026-07-31

Conditions

• LRG Levels

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04507308 | COMPLETED | NA

57 participants

Real-time Experiences With Sleep Training Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2024-06-01

Completion:

2026-06-21

Conditions

• Borderline Personality Disorder
• Sleep Disturbance

Interventions

• BEHAVIORAL

No Results Yet

NCT04495504 | COMPLETED | PHASE2

32 participants

Administration of Ropivacaine by Bi-laterosternal Multiperforated Catheters Placed Before a Sternotomy for Cardiac Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-07-22

Completion:

2021-01-12

Conditions

• Scheduled Cardiac Surgery
• Age Under 85 Years

Interventions

• DRUG

No Results Yet

NCT04441307 | COMPLETED | NA

368 participants

Promoting Co-Parenting and Reducing Hazardous Drinking in New Families

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-01-25

Completion:

2026-01-19

Conditions

• Parenting
• Parent-Child Relations
• Drinking, Alcohol
• Adjustment

Interventions

• BEHAVIORAL

No Results Yet

NCT04438382 | TERMINATED | PHASE2

1 participants

Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-01-07

Completion:

2023-12-21

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm
• Steroid-Refractory Pneumonitis

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04433065 | ACTIVE_NOT_RECRUITING | NA

150 participants

TTVR Early Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-10-20

Completion:

2026-09-10

Conditions

• Tricuspid Regurgitation

Interventions

• DEVICE

No Results Yet

NCT04403633 | RECRUITING | NA

25 participants

A Study of Facilitators and Barriers to Improve Acute Kidney Injury in Children Through Mobile Health Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-06-01

Completion:

2026-12-31

Conditions

• Acute Kidney Injury

Interventions

• OTHER

No Results Yet

NCT04371016 | COMPLETED | NA

30 participants

Pulmonary and Ventilatory Effects of Bed Verticalization in Patients With Acute Respiratory Distress Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-03-30

Completion:

2021-01-14

Conditions

• Acute Respiratory Distress Syndrome

Interventions

• OTHER

No Results Yet

NCT04355312 | COMPLETED | NA

51 participants

Using INDOcyanine Green to Analyse Ovarian Vascularization After Ovarian Laparoscopic CYStectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-06-15

Completion:

2022-12-12

Conditions

• Ovarian Cysts
• Endometriosis
• Fertility

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04334083 | COMPLETED | NA

48 participants

Biomarkes Of Job STRess In Emergency Senior Physicians - Detection of Stressful Events

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2022-02-17

Completion:

2023-12-21

Conditions

• Heart Rate Variability

Interventions

• BEHAVIORAL

No Results Yet

NCT04326478 | COMPLETED | PHASE2

2475 participants

Single Dose Azithromycin to Prevent Cholera in Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-10-31

Completion:

2025-05-31

Conditions

• Cholera

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04305431 | ACTIVE_NOT_RECRUITING | NA

43 participants

Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2021-02-25

Completion:

2027-12-19

Conditions

• Diet
• Cooking

Interventions

• BEHAVIORAL

No Results Yet

NCT04291612 | RECRUITING

1715 participants

Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-07

Start Date:

2020-02-26

Completion:

2027-02-26

Conditions

• Endometrial Cancer
• Endometrioid Adenocarcinoma
• Endometrial Cancer Stage I

Interventions

• OTHER

No Results Yet

NCT04284943 | RECRUITING | NA

120 participants

Surgical TreAtment for Obesity Related Disease and Onco-Metabolic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-12-01

Completion:

2027-12-31

Conditions

• Gastric Cancer
• Diabetes Mellitus, Type 2

Interventions

• PROCEDURE

No Results Yet

NCT04280081 | ACTIVE_NOT_RECRUITING | PHASE2

77 participants

A Study of Selpercatinib (LY3527723) in Participants With Advanced Solid Tumors Including RET Fusion-positive Solid Tumors, Medullary Thyroid Cancer and Other Tumors With RET Activation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-03-16

Completion:

2021-03-25

Conditions

• Solid Tumor
• Medullary Thyroid Cancer

Interventions

• DRUG

Results Available

NCT04269200 | ACTIVE_NOT_RECRUITING | PHASE3

805 participants

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-05-05

Completion:

2024-07-08

Conditions

• Endometrial Neoplasms

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04251052 | RECRUITING | NA

1956 participants

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-09-01

Completion:

2047-06-30

Conditions

• Ovarian Carcinoma

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04236518 | COMPLETED | NA

53 participants

Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-08-27

Completion:

2022-08-05

Conditions

• Metabolic Syndrome
• Hypertriglyceridemia
• Fasting Blood Sugar Above Normal
• Lower Than Standard HDL-cholesterol Level
• Slightly Elevated Blood Pressure

Interventions

• BEHAVIORAL

No Results Yet

NCT04209751 | COMPLETED

95 participants

Descriptive Study of Pathogens Involved in Summer Diarrhea in Children Leading to Pediatric Emergency Room Visits (PE-DIA)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-07

Start Date:

2020-06-01

Completion:

2020-09-30

Conditions

• Diarrhea, Infantile

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04174209 | COMPLETED | NA

52 participants

CHOICE OF SUBJECTIVE OCULAR REFRACTION TECHNIQUE AND CORNEAL TOPOGRAPHY OF KERATOCONUS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2019-11-18

Completion:

2020-03-06

Conditions

• Keratoconus
• Alteration of Visual Acuity

Interventions

• BEHAVIORAL

No Results Yet

NCT04146545 | COMPLETED | NA

360 participants

CommunityRx-Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2019-12-16

Completion:

2024-03-19

Conditions

• Health Related Social Needs (HRSN)

Interventions

• BEHAVIORAL

Results Available

NCT04145349 | COMPLETED | PHASE1/PHASE2

30 participants

CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2020-01-22

Completion:

2024-06-14

Conditions

• Desmoplastic Small Round Cell Tumor

Interventions

• DRUG

Results Available

NCT04099251 | ACTIVE_NOT_RECRUITING | PHASE3

790 participants

Effectiveness Study of Nivolumab Compared to Placebo in Prevention of Recurrent Melanoma After Complete Resection of Stage IIB/C Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2019-10-28

Completion:

2022-06-28

Conditions

• Melanoma

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04070469 | COMPLETED | PHASE4

142 participants

Plasma Concentrations of Amoxicillin Administered in High-doses During the First Week of Treatment (MAX-AMOX)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-07

Start Date:

2019-12-04

Completion:

2024-12-19

Conditions

• Infection, Bacterial

Interventions

• DRUG

No Results Yet