Clinical Trials

NCT06505993 | WITHDRAWN | NA

0 participants

Addressing COVID-19 Vaccine Hesitancy With Muliti-Level Interventions in Appalachia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-30

Completion:

2027-09-30

Conditions

• COVID-19
• Vaccine Hesitancy

Interventions

• BEHAVIORAL

No Results Yet

NCT06498713 | COMPLETED | PHASE1

24 participants

Patient Controlled Administration of Liquid Acetaminophen

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-11-19

Completion:

2026-03-28

Conditions

• Pain
• Pain, Postoperative

Interventions

• DRUG
• DEVICE

No Results Yet

NCT06484621 | RECRUITING | NA

164 participants

Motivating Increases in Physical Activity for Prevention of Weight Regain After Metabolic Bariatric Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-08

Completion:

2028-09-28

Conditions

• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT06483100 | RECRUITING | PHASE2

65 participants

Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-12-20

Completion:

2032-06-30

Conditions

• Multiple Myeloma

Interventions

• DRUG
• DEVICE

No Results Yet

NCT06477471 | COMPLETED | NA

14 participants

A Clinical Study to Determine the Safety and Efficacy of An Oral Probiotic. Supplementation in Reducing the Risk of Kidney Stone in Adults With Recurrent Kidney Stone Colic or Acute Episode of Colicky Pain.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-11-29

Completion:

2025-01-07

Conditions

• Recurrent Kidney Stones With Colicky Pain

Interventions

• OTHER

No Results Yet

NCT06475989 | RECRUITING | PHASE3

264 participants

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-22

Completion:

2030-09-30

Conditions

• Refractory Differentiated Thyroid Gland Carcinoma

Interventions

• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT06469021 | COMPLETED | NA

25 participants

Effectiveness of Rehabilitation With Technology-Based Systems in Adolescent Idiopathic Scoliosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-14

Completion:

2026-03-01

Conditions

• Scoliosis; Adolescence

Interventions

• OTHER

No Results Yet

NCT06461897 | RECRUITING | PHASE3

675 participants

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-19

Completion:

2030-07-31

Conditions

• Atopic Dermatitis

Interventions

• DRUG

No Results Yet

NCT06456463 | ACTIVE_NOT_RECRUITING | PHASE2

85 participants

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-01-14

Completion:

2028-02-09

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT06450444 | RECRUITING | NA

110 participants

The RECLAIM Study.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-24

Completion:

2027-04-01

Conditions

• Chronic Migraine
• High Frequency Episodic Migraine

Interventions

• DEVICE

No Results Yet

NCT06444880 | ACTIVE_NOT_RECRUITING | PHASE2

15 participants

Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-09

Completion:

2027-07-31

Conditions

• SMARCB1-Deficient Malignancies
• Epithelioid Sarcoma
• Renal Medullary Carcinoma

Interventions

• DRUG

No Results Yet

NCT06439836 | RECRUITING | PHASE1

27 participants

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-05-05

Completion:

2027-06-01

Conditions

• Metastatic Urothelial Carcinoma
• Unresectable Urothelial Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT06439693 | RECRUITING | PHASE2

72 participants

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-08

Completion:

2030-03-30

Conditions

• Breast Cancer Female
• Breast Cancer
• Breast Cancer Metastatic
• Estrogen Receptor-positive Breast Cancer
• HER2-positive Breast Cancer
• Stage IV Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06431022 | COMPLETED | NA

70 participants

Web-administered STAIR for Patients on Behavioral Health Waitlists

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-11-15

Completion:

2026-06-05

Conditions

• Post Traumatic Stress Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT06429787 | RECRUITING

3574 participants

Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-02-14

Completion:

2031-12-31

Conditions

• Vitamin K-Dependent Coagulation Defect
• Significant Bleeding Risk

Interventions

• DRUG

No Results Yet

NCT06424288 | RECRUITING | PHASE3

6000 participants

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-17

Completion:

2028-05-22

Conditions

• Heart Failure

Interventions

• DRUG

No Results Yet

NCT06421506 | RECRUITING | NA

245 participants

Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-08

Completion:

2027-09-30

Conditions

• Respiratory Distress Syndrome
• Preterm Pregnancy
• Surfactant Deficiency Syndrome Neonatal

Interventions

• PROCEDURE

No Results Yet

NCT06421155 | SUSPENDED | NA

20 participants

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-04

Completion:

2027-06-14

Conditions

• Acute Leukemia
• Acute Lymphoblastic Leukemia, Pediatric
• Acute Myeloid Leukemia in Children
• Myeloproliferative Neoplasm

Interventions

• OTHER

No Results Yet

NCT06417190 | RECRUITING | PHASE2

20 participants

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-01-16

Completion:

2030-12-31

Conditions

• Muscle-Invasive Bladder Carcinoma
• Tumor

Interventions

• DRUG

No Results Yet

NCT06406777 | RECRUITING | PHASE1/PHASE2

100 participants

Chronic Lung Allograft Dysfunction MRI Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-03-20

Completion:

2028-09-30

Conditions

• Chronic Lung Allograft Dysfunction Lung MRI (CLAD)

Interventions

• DIAGNOSTIC_TEST
• DRUG

No Results Yet

NCT06404242 | RECRUITING

75 participants

Plaque Characteristics Predict Recurrent Stroke in MCA Stroke Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-27

Completion:

2026-12-31

Conditions

• High Resolution Vessel Wall Imaging
• Recurrent Stroke
• Stroke, Mechanism
• Atheroscleroses, Intracranial
• Stroke, Infarct Pattern

No Results Yet

NCT06397066 | COMPLETED

384 participants

White Light Endoscopy and Magnifying Endoscopy in Assessing the Status of Hp Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-01

Completion:

2026-07-31

Conditions

• Helicobacter Pylori Infection

Interventions

• PROCEDURE

No Results Yet

NCT06386887 | RECRUITING | NA

20 participants

Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-07-11

Completion:

2026-11-30

Conditions

• Epithelial Ovarian Cancer

Interventions

• BEHAVIORAL
• DRUG

No Results Yet

NCT06373497 | RECRUITING | EARLY_PHASE1

10 participants

Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-06-19

Completion:

2026-10-31

Conditions

• Oligometastatic Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06361537 | RECRUITING | PHASE3

124 participants

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-30

Completion:

2026-12-31

Conditions

• Acute Hereditary Angio Edema

Interventions

• DRUG
• OTHER

No Results Yet

NCT06353191 | RECRUITING

693 participants

Biomarkers to Predict Cancer Therapy-related Cardiotoxicity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2019-05-03

Completion:

2031-12-31

Conditions

• Hematopoietic and Lymphatic System Neoplasm
• Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT06351722 | COMPLETED

100 participants

Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-25

Completion:

2025-12-15

Conditions

• Periodontitis, Adult

Interventions

• DIAGNOSTIC_TEST
• PROCEDURE

No Results Yet

NCT06347016 | ACTIVE_NOT_RECRUITING | PHASE3

311 participants

Study of Plozasiran in Adults With Severe Hypertriglyceridemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-07-23

Completion:

2026-06-17

Conditions

• Severe Hypertriglyceridemia

Interventions

• DRUG

No Results Yet

NCT06340659 | ACTIVE_NOT_RECRUITING | NA

104 participants

Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults (The Exergames Telerehabilitation Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-14

Completion:

2026-11-30

Conditions

• At Risk for AD-dementia, With Subjective Cognitive Decline

Interventions

• BEHAVIORAL

No Results Yet

NCT06338995 | RECRUITING | PHASE3

510 participants

A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-29

Completion:

2027-05-31

Conditions

• Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Interventions

• DRUG

No Results Yet

NCT06335953 | COMPLETED | NA

474 participants

ALIGN: Aligning Medications With What Matters Most (Demonstration)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-07

Completion:

2025-09-16

Conditions

• Polypharmacy
• Alzheimer's Disease and Related Dementias
• Mild Cognitive Impairment

Interventions

• BEHAVIORAL

Results Available

NCT06335771 | RECRUITING | NA

60 participants

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-01

Completion:

2028-03-31

Conditions

• Obesity
• Nonalcoholic Fatty Liver
• Diabetes Type 2
• Healthy

Interventions

• OTHER

No Results Yet

NCT06324357 | RECRUITING | PHASE1/PHASE2

768 participants

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-28

Completion:

2029-01-08

Conditions

• Metastatic Breast Cancer
• Metastatic Gastric Adenocarcinoma
• Gastroesophageal Junction Adenocarcinoma
• Esophageal Adenocarcinoma
• Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT06305338 | COMPLETED

110 participants

Predicting Intraocular Lens Tilt Using OCT Measurements and Partial Least Squares Regression Modelling

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2022-04-12

Completion:

2023-04-01

Conditions

• Intraocular Lens
• Cataract

Interventions

• OTHER

No Results Yet

NCT06304168 | RECRUITING

6150 participants

Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2019-05-13

Completion:

2028-05-15

Conditions

• Hematopoietic and Lymphatic System Neoplasm
• Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT06300892 | COMPLETED

71 participants

Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-01

Completion:

2026-05-15

Conditions

• Open GI Surgery

Interventions

• OTHER

No Results Yet

NCT06290687 | RECRUITING | PHASE2

40 participants

Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-30

Completion:

2026-12-29

Conditions

• Malignant Neoplasm of Bladder
• Muscle Invasive Bladder Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT06287775 | RECRUITING | PHASE1/PHASE2

45 participants

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-04-08

Completion:

2029-07-25

Conditions

• Extensive Stage Lung Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT06287151 | COMPLETED | NA

80 participants

Regional Anesthesia EMG Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-09

Completion:

2025-02-28

Conditions

• Surgery

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06276764 | ENROLLING_BY_INVITATION

500 participants

The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-15

Completion:

2034-09-30

Conditions

• IPMN, Pancreatic
• Pancreas Cancer
• Pancreatic Cyst

Interventions

• DIAGNOSTIC_TEST

No Results Yet