Clinical Trials

NCT06439836 | RECRUITING | PHASE1

27 participants

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-05-05

Completion:

2027-06-01

Conditions

• Metastatic Urothelial Carcinoma
• Unresectable Urothelial Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT06439693 | RECRUITING | PHASE2

72 participants

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-08

Completion:

2030-03-30

Conditions

• Breast Cancer Female
• Breast Cancer
• Breast Cancer Metastatic
• Estrogen Receptor-positive Breast Cancer
• HER2-positive Breast Cancer
• Stage IV Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06431022 | COMPLETED | NA

70 participants

Web-administered STAIR for Patients on Behavioral Health Waitlists

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-11-15

Completion:

2026-06-05

Conditions

• Post Traumatic Stress Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT06429787 | RECRUITING

3574 participants

Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-02-14

Completion:

2031-12-31

Conditions

• Vitamin K-Dependent Coagulation Defect
• Significant Bleeding Risk

Interventions

• DRUG

No Results Yet

NCT06424288 | RECRUITING | PHASE3

6000 participants

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-17

Completion:

2028-05-22

Conditions

• Heart Failure

Interventions

• DRUG

No Results Yet

NCT06421506 | RECRUITING | NA

245 participants

Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-08

Completion:

2027-09-30

Conditions

• Respiratory Distress Syndrome
• Preterm Pregnancy
• Surfactant Deficiency Syndrome Neonatal

Interventions

• PROCEDURE

No Results Yet

NCT06421155 | SUSPENDED | NA

20 participants

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-04

Completion:

2027-06-14

Conditions

• Acute Leukemia
• Acute Lymphoblastic Leukemia, Pediatric
• Acute Myeloid Leukemia in Children
• Myeloproliferative Neoplasm

Interventions

• OTHER

No Results Yet

NCT06417190 | RECRUITING | PHASE2

20 participants

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-01-16

Completion:

2030-12-31

Conditions

• Muscle-Invasive Bladder Carcinoma
• Tumor

Interventions

• DRUG

No Results Yet

NCT06406777 | RECRUITING | PHASE1/PHASE2

100 participants

Chronic Lung Allograft Dysfunction MRI Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-03-20

Completion:

2028-09-30

Conditions

• Chronic Lung Allograft Dysfunction Lung MRI (CLAD)

Interventions

• DIAGNOSTIC_TEST
• DRUG

No Results Yet

NCT06404242 | RECRUITING

75 participants

Plaque Characteristics Predict Recurrent Stroke in MCA Stroke Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-27

Completion:

2026-12-31

Conditions

• High Resolution Vessel Wall Imaging
• Recurrent Stroke
• Stroke, Mechanism
• Atheroscleroses, Intracranial
• Stroke, Infarct Pattern

No Results Yet

NCT06397066 | COMPLETED

384 participants

White Light Endoscopy and Magnifying Endoscopy in Assessing the Status of Hp Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-01

Completion:

2026-07-31

Conditions

• Helicobacter Pylori Infection

Interventions

• PROCEDURE

No Results Yet

NCT06386887 | RECRUITING | NA

20 participants

Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-07-11

Completion:

2026-11-30

Conditions

• Epithelial Ovarian Cancer

Interventions

• BEHAVIORAL
• DRUG

No Results Yet

NCT06373497 | RECRUITING | EARLY_PHASE1

10 participants

Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-06-19

Completion:

2026-10-31

Conditions

• Oligometastatic Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06361537 | RECRUITING | PHASE3

124 participants

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-30

Completion:

2026-12-31

Conditions

• Acute Hereditary Angio Edema

Interventions

• DRUG
• OTHER

No Results Yet

NCT06351722 | COMPLETED

100 participants

Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-25

Completion:

2025-12-15

Conditions

• Periodontitis, Adult

Interventions

• DIAGNOSTIC_TEST
• PROCEDURE

No Results Yet

NCT06347016 | ACTIVE_NOT_RECRUITING | PHASE3

311 participants

Study of Plozasiran in Adults With Severe Hypertriglyceridemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-07-23

Completion:

2026-06-17

Conditions

• Severe Hypertriglyceridemia

Interventions

• DRUG

No Results Yet

NCT06340659 | ACTIVE_NOT_RECRUITING | NA

104 participants

Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults (The Exergames Telerehabilitation Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-14

Completion:

2026-11-30

Conditions

• At Risk for AD-dementia, With Subjective Cognitive Decline

Interventions

• BEHAVIORAL

No Results Yet

NCT06338995 | RECRUITING | PHASE3

510 participants

A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-29

Completion:

2027-05-31

Conditions

• Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Interventions

• DRUG

No Results Yet

NCT06335953 | COMPLETED | NA

474 participants

ALIGN: Aligning Medications With What Matters Most (Demonstration)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-07

Completion:

2025-09-16

Conditions

• Polypharmacy
• Alzheimer's Disease and Related Dementias
• Mild Cognitive Impairment

Interventions

• BEHAVIORAL

Results Available

NCT06335771 | RECRUITING | NA

60 participants

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-01

Completion:

2028-03-31

Conditions

• Obesity
• Nonalcoholic Fatty Liver
• Diabetes Type 2
• Healthy

Interventions

• OTHER

No Results Yet

NCT06324357 | RECRUITING | PHASE1/PHASE2

768 participants

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-28

Completion:

2029-01-08

Conditions

• Metastatic Breast Cancer
• Metastatic Gastric Adenocarcinoma
• Gastroesophageal Junction Adenocarcinoma
• Esophageal Adenocarcinoma
• Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT06305338 | COMPLETED

110 participants

Predicting Intraocular Lens Tilt Using OCT Measurements and Partial Least Squares Regression Modelling

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2022-04-12

Completion:

2023-04-01

Conditions

• Intraocular Lens
• Cataract

Interventions

• OTHER

No Results Yet

NCT06300892 | COMPLETED

71 participants

Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-01

Completion:

2026-05-15

Conditions

• Open GI Surgery

Interventions

• OTHER

No Results Yet

NCT06290687 | RECRUITING | PHASE2

40 participants

Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-30

Completion:

2026-12-29

Conditions

• Malignant Neoplasm of Bladder
• Muscle Invasive Bladder Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT06287775 | RECRUITING | PHASE1/PHASE2

45 participants

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-04-08

Completion:

2029-07-25

Conditions

• Extensive Stage Lung Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT06287151 | COMPLETED | NA

80 participants

Regional Anesthesia EMG Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-09

Completion:

2025-02-28

Conditions

• Surgery

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06276764 | ENROLLING_BY_INVITATION

500 participants

The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-15

Completion:

2034-09-30

Conditions

• IPMN, Pancreatic
• Pancreas Cancer
• Pancreatic Cyst

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06275724 | ACTIVE_NOT_RECRUITING

585 participants

Specified Drug-use Survey of Leqvio for s.c. Injection.

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-03-04

Completion:

2026-12-17

Conditions

• Familial Hypercholesterolaemia
• Hypercholesterolaemia

Interventions

• OTHER

No Results Yet

NCT06274515 | RECRUITING | PHASE4

320 participants

A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-02

Completion:

2026-09-30

Conditions

• Breast Cancer

Interventions

• PROCEDURE

No Results Yet

NCT06263244 | ACTIVE_NOT_RECRUITING | PHASE3

40 participants

Specifying the Anti-inflammatory Effects of Ziltivekimab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-03

Completion:

2026-09-04

Conditions

• Atherosclerosis
• Inflammation

Interventions

• DRUG

No Results Yet

NCT06259500 | ACTIVE_NOT_RECRUITING

20 participants

Patient-derived Stem Cell Models of Anorexia Nervosa

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2022-08-25

Completion:

2026-12-31

Conditions

• Anorexia Nervosa

Interventions

• OTHER

No Results Yet

NCT06237582 | COMPLETED | NA

20 participants

Inferior Epigastric Lymp Node (IELN) Basin as a Possible Systemic Metastatic Pathway of Ovarian Peritoneal Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-06-16

Completion:

2023-01-01

Conditions

• Carcinomatosis, Peritoneal

Interventions

• PROCEDURE

No Results Yet

NCT06233370 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

24 participants

Acute Effects of Walking Exercise on Brain Functioning in Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-03-01

Completion:

2025-02-28

Conditions

• Multiple Sclerosis

Interventions

• BEHAVIORAL

No Results Yet

NCT06233344 | RECRUITING | PHASE2

40 participants

Mindfulness-Assisted Psychedelic Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-07-30

Completion:

2027-08-31

Conditions

• Mental Health

Interventions

• DRUG

No Results Yet

NCT06223789 | COMPLETED | NA

392 participants

VOLT-AF IDE Clinical Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-03

Completion:

2025-10-03

Conditions

• Atrial Arrhythmia
• Atrial Fibrillation
• Paroxysmal Atrial Fibrillation
• Persistent Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT06214156 | RECRUITING | PHASE1/PHASE2

42 participants

A Clinical Study of T3011 in Subjects With Advanced Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-26

Completion:

2026-09-30

Conditions

• Advanced Melanoma

Interventions

• BIOLOGICAL

No Results Yet

NCT06212570 | NOT_YET_RECRUITING | NA

12 participants

KeyScope Study in Uganda

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-01

Completion:

2027-06-30

Conditions

• Abdominal Neoplasm

Interventions

• DEVICE

No Results Yet

NCT06206954 | ENROLLING_BY_INVITATION | NA

864 participants

Supporting Decisions on Lifestyle Change

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-24

Completion:

2028-04-30

Conditions

• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT06203210 | RECRUITING | PHASE3

540 participants

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-21

Completion:

2028-01-30

Conditions

• Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT06201936 | COMPLETED

1346 participants

EPIDURAL- Evaluation of Preexisting Information Regarding Neuroaxial Procedures for Labour Analgesia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-03-01

Completion:

2026-08-01

Conditions

• Neuroaxial Analgesia Procedures

Interventions

• BEHAVIORAL

No Results Yet