Clinical Trials

NCT06439693 | RECRUITING | PHASE2

72 participants

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-08-08
Completion:: 2030-03-30

Conditions

Breast Cancer Female
Breast Cancer
Breast Cancer Metastatic
Estrogen Receptor-positive Breast Cancer
HER2-positive Breast Cancer
Stage IV Breast Cancer

Interventions

DRUG

No Results Yet

NCT06431022 | COMPLETED | NA

70 participants

Web-administered STAIR for Patients on Behavioral Health Waitlists

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-11-15
Completion:: 2026-06-05

Conditions

Post Traumatic Stress Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06429787 | RECRUITING

3574 participants

Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-02-14
Completion:: 2031-12-31

Conditions

Vitamin K-Dependent Coagulation Defect
Significant Bleeding Risk

Interventions

DRUG

No Results Yet

NCT06424288 | RECRUITING | PHASE3

6000 participants

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-06-17
Completion:: 2028-05-22

Conditions

Heart Failure

Interventions

DRUG

No Results Yet

NCT06421506 | RECRUITING | NA

245 participants

Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-05-08
Completion:: 2027-09-30

Conditions

Respiratory Distress Syndrome
Preterm Pregnancy
Surfactant Deficiency Syndrome Neonatal

Interventions

PROCEDURE

No Results Yet

NCT06421155 | SUSPENDED | NA

20 participants

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-10-04
Completion:: 2027-06-14

Conditions

Acute Leukemia
Acute Lymphoblastic Leukemia, Pediatric
Acute Myeloid Leukemia in Children
Myeloproliferative Neoplasm

Interventions

OTHER

No Results Yet

NCT06417190 | RECRUITING | PHASE2

20 participants

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-01-16
Completion:: 2030-12-31

Conditions

Muscle-Invasive Bladder Carcinoma
Tumor

Interventions

DRUG

No Results Yet

NCT06406777 | RECRUITING | PHASE1/PHASE2

100 participants

Chronic Lung Allograft Dysfunction MRI Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-03-20
Completion:: 2028-09-30

Conditions

Chronic Lung Allograft Dysfunction Lung MRI (CLAD)

Interventions

DIAGNOSTIC_TEST
DRUG

No Results Yet

NCT06404242 | RECRUITING

75 participants

Plaque Characteristics Predict Recurrent Stroke in MCA Stroke Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-05-27
Completion:: 2026-12-31

Conditions

High Resolution Vessel Wall Imaging
Recurrent Stroke
Stroke, Mechanism
Atheroscleroses, Intracranial
Stroke, Infarct Pattern

No Results Yet

NCT06397066 | COMPLETED

384 participants

White Light Endoscopy and Magnifying Endoscopy in Assessing the Status of Hp Infection

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-05-01
Completion:: 2026-07-31

Conditions

Helicobacter Pylori Infection

Interventions

PROCEDURE

No Results Yet

NCT06386887 | RECRUITING | NA

20 participants

Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-07-11
Completion:: 2026-11-30

Conditions

Epithelial Ovarian Cancer

Interventions

BEHAVIORAL
DRUG

No Results Yet

NCT06373497 | RECRUITING | EARLY_PHASE1

10 participants

Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-06-19
Completion:: 2026-10-31

Conditions

Oligometastatic Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06361537 | RECRUITING | PHASE3

124 participants

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-04-30
Completion:: 2026-12-31

Conditions

Acute Hereditary Angio Edema

Interventions

DRUG
OTHER

No Results Yet

NCT06351722 | COMPLETED

100 participants

Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-06-25
Completion:: 2025-12-15

Conditions

Periodontitis, Adult

Interventions

DIAGNOSTIC_TEST
PROCEDURE

No Results Yet

NCT06347016 | ACTIVE_NOT_RECRUITING | PHASE3

311 participants

Study of Plozasiran in Adults With Severe Hypertriglyceridemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-07-23
Completion:: 2026-06-17

Conditions

Severe Hypertriglyceridemia

Interventions

DRUG

No Results Yet

NCT06340659 | ACTIVE_NOT_RECRUITING | NA

104 participants

Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults (The Exergames Telerehabilitation Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-08-14
Completion:: 2026-11-30

Conditions

At Risk for AD-dementia, With Subjective Cognitive Decline

Interventions

BEHAVIORAL

No Results Yet

NCT06338995 | RECRUITING | PHASE3

510 participants

A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-04-29
Completion:: 2027-05-31

Conditions

Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Interventions

DRUG

No Results Yet

NCT06335953 | COMPLETED | NA

474 participants

ALIGN: Aligning Medications With What Matters Most (Demonstration)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-05-07
Completion:: 2025-09-16

Conditions

Polypharmacy
Alzheimer's Disease and Related Dementias
Mild Cognitive Impairment

Interventions

BEHAVIORAL

Results Available

NCT06335771 | RECRUITING | NA

60 participants

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-08-01
Completion:: 2028-03-31

Conditions

Obesity
Nonalcoholic Fatty Liver
Diabetes Type 2
Healthy

Interventions

OTHER

No Results Yet

NCT06324357 | RECRUITING | PHASE1/PHASE2

768 participants

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-06-28
Completion:: 2029-01-08

Conditions

Metastatic Breast Cancer
Metastatic Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Esophageal Adenocarcinoma
Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06305338 | COMPLETED

110 participants

Predicting Intraocular Lens Tilt Using OCT Measurements and Partial Least Squares Regression Modelling

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-04-12
Completion:: 2023-04-01

Conditions

Intraocular Lens
Cataract

Interventions

OTHER

No Results Yet

NCT06304168 | RECRUITING

6150 participants

Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2019-05-13
Completion:: 2028-05-15

Conditions

Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT06300892 | COMPLETED

71 participants

Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-04-01
Completion:: 2026-05-15

Conditions

Open GI Surgery

Interventions

OTHER

No Results Yet

NCT06290687 | RECRUITING | PHASE2

40 participants

Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-09-30
Completion:: 2026-12-29

Conditions

Malignant Neoplasm of Bladder
Muscle Invasive Bladder Carcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06287775 | RECRUITING | PHASE1/PHASE2

45 participants

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-04-08
Completion:: 2029-07-25

Conditions

Extensive Stage Lung Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8

Interventions

BIOLOGICAL
PROCEDURE
DRUG

No Results Yet

NCT06287151 | COMPLETED | NA

80 participants

Regional Anesthesia EMG Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-08-09
Completion:: 2025-02-28

Conditions

Surgery

Interventions

DEVICE
DRUG

No Results Yet

NCT06276764 | ENROLLING_BY_INVITATION

500 participants

The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-10-15
Completion:: 2034-09-30

Conditions

IPMN, Pancreatic
Pancreas Cancer
Pancreatic Cyst

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06275724 | ACTIVE_NOT_RECRUITING

585 participants

Specified Drug-use Survey of Leqvio for s.c. Injection.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-03-04
Completion:: 2026-12-17

Conditions

Familial Hypercholesterolaemia
Hypercholesterolaemia

Interventions

OTHER

No Results Yet

NCT06274515 | RECRUITING | PHASE4

320 participants

A Study to Investigate Mechanisms of Resistance to Breast Cancer Therapies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-04-02
Completion:: 2026-09-30

Conditions

Breast Cancer

Interventions

PROCEDURE

No Results Yet

NCT06263244 | ACTIVE_NOT_RECRUITING | PHASE3

40 participants

Specifying the Anti-inflammatory Effects of Ziltivekimab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-05-03
Completion:: 2026-09-04

Conditions

Atherosclerosis
Inflammation

Interventions

DRUG

No Results Yet

NCT06259500 | ACTIVE_NOT_RECRUITING

20 participants

Patient-derived Stem Cell Models of Anorexia Nervosa

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-08-25
Completion:: 2026-12-31

Conditions

Anorexia Nervosa

Interventions

OTHER

No Results Yet

NCT06238622 | RECRUITING | PHASE3

1700 participants

A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-05-06
Completion:: 2027-04-28

Conditions

Idiopathic Pulmonary Fibrosis
Progressive Pulmonary Fibrosis

Interventions

DRUG

No Results Yet

NCT06237582 | COMPLETED | NA

20 participants

Inferior Epigastric Lymp Node (IELN) Basin as a Possible Systemic Metastatic Pathway of Ovarian Peritoneal Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-06-16
Completion:: 2023-01-01

Conditions

Carcinomatosis, Peritoneal

Interventions

PROCEDURE

No Results Yet

NCT06233370 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

24 participants

Acute Effects of Walking Exercise on Brain Functioning in Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-03-01
Completion:: 2025-02-28

Conditions

Multiple Sclerosis

Interventions

BEHAVIORAL

No Results Yet

NCT06233344 | RECRUITING | PHASE2

40 participants

Mindfulness-Assisted Psychedelic Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-07-30
Completion:: 2027-08-31

Conditions

Mental Health

Interventions

DRUG

No Results Yet

NCT06223789 | COMPLETED | NA

392 participants

VOLT-AF IDE Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-04-03
Completion:: 2025-10-03

Conditions

Atrial Arrhythmia
Atrial Fibrillation
Paroxysmal Atrial Fibrillation
Persistent Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT06214156 | RECRUITING | PHASE1/PHASE2

42 participants

A Clinical Study of T3011 in Subjects With Advanced Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-01-26
Completion:: 2026-09-30

Conditions

Advanced Melanoma

Interventions

BIOLOGICAL

No Results Yet

NCT06212570 | NOT_YET_RECRUITING | NA

12 participants

KeyScope Study in Uganda

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-09-01
Completion:: 2027-06-30

Conditions

Abdominal Neoplasm

Interventions

DEVICE

No Results Yet

NCT06206954 | ENROLLING_BY_INVITATION | NA

864 participants

Supporting Decisions on Lifestyle Change

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-01-24
Completion:: 2028-04-30

Conditions

Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06203210 | RECRUITING | PHASE3

540 participants

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-05-21
Completion:: 2028-01-30

Conditions

Small Cell Lung Cancer

Interventions

DRUG

No Results Yet