Clinical Trials

NCT06577298 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

480 participants

A Study to Evaluate the Safety and Immunogenicity of VLP-Polio in Infants and Toddlers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-12-19

Completion:

2026-10-31

Conditions

• Poliomyelitis

Interventions

• BIOLOGICAL

No Results Yet

NCT06575192 | RECRUITING | PHASE3

264 participants

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-11-05

Completion:

2031-02-28

Conditions

• Breast Reconstruction

Interventions

• DEVICE

No Results Yet

NCT06571669 | RECRUITING | NA

137 participants

BOOM-IBD2 Pivotal Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-01-31

Completion:

2027-02-28

Conditions

• Ulcerative Colitis
• Inflammatory Bowel Diseases

Interventions

• DEVICE

No Results Yet

NCT06571474 | RECRUITING

60 participants

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-01

Completion:

2028-03-31

Conditions

• Obesity
• Non-Alcoholic Fatty Liver Disease
• Diabetes Mellitus, Type 2
• Healthy

No Results Yet

NCT06566339 | RECRUITING | NA

93 participants

Robotic OCT for ER Anterior Eye Exams

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-06-29

Completion:

2026-12-30

Conditions

• Develop and Test Robotically Assisted Imaging System for the Front of the Eye

Interventions

• DEVICE

No Results Yet

NCT06559150 | RECRUITING | PHASE2

284 participants

A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-09-11

Completion:

2027-09-24

Conditions

• Non-cystic Fibrosis Bronchiectasis

Interventions

• DRUG

No Results Yet

NCT06552039 | COMPLETED | NA

99 participants

Proof-of-Science, Prospective, Interventional, Three-arm, Double-Blind, Randomized, Safety and Efficacy Real World Evidence Study.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-12-26

Completion:

2025-06-28

Conditions

• Hair Fall and Pre-mature Graying

Interventions

• OTHER

No Results Yet

NCT06548061 | NOT_YET_RECRUITING | NA

25 participants

D20054;LITT for Spine Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2028-01-01

Completion:

2031-06-30

Conditions

• Spinal Metastases

Interventions

• DEVICE

No Results Yet

NCT06545955 | RECRUITING | PHASE3

250 participants

A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-01

Completion:

2028-06-30

Conditions

• Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

Interventions

• DRUG

No Results Yet

NCT06543745 | COMPLETED | NA

19 participants

Safety and Impact of Low Resistance Exercise Training on Quality of Life in Pulmonary Arterial Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-09-04

Completion:

2026-03-31

Conditions

• Pulmonary Arterial Hypertension
• Frailty

Interventions

• BEHAVIORAL

No Results Yet

NCT06534983 | ACTIVE_NOT_RECRUITING | PHASE2

62 participants

A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-risk Muscle-invasive Urothelial Carcinoma (MIUC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-12-09

Completion:

2027-11-10

Conditions

• Muscle-invasive Urothelial Carcinoma

Interventions

• DRUG

No Results Yet

NCT06533579 | RECRUITING | PHASE1/PHASE2

32 participants

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-05-30

Completion:

2027-06-30

Conditions

• B-cell Acute Lymphoblastic Leukemia
• Large B-cell Lymphoma
• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma
• Marginal Zone Lymphoma
• Follicular Lymphoma
• Mantle Cell Lymphoma
• Diffuse Large B Cell Lymphoma
• High-grade B-cell Lymphoma
• Burkitt Lymphoma
• Primary Mediastinal Large B-cell Lymphoma (PMBCL)
• Non Hodgkin Lymphoma
• Mixed Phenotype Acute Leukemia

Interventions

• GENETIC

No Results Yet

NCT06516926 | TERMINATED | PHASE2

11 participants

SHR-4602 for Injection in Subjects With HER2-expressing or -Mutated Unresectable or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-08

Completion:

2025-05-23

Conditions

• HER2-expressing or -Mutated Unresectable or Metastatic Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06510010 | RECRUITING | PHASE2

198 participants

Perioperative Oxaliplatin With S-1 Combined H. Pylori Eradication in the Management of Locally Advanced Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-12-31

Completion:

2026-12-28

Conditions

• Chemotherapy Effect

Interventions

• DRUG

No Results Yet

NCT06505993 | WITHDRAWN | NA

0 participants

Addressing COVID-19 Vaccine Hesitancy With Muliti-Level Interventions in Appalachia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-30

Completion:

2027-09-30

Conditions

• COVID-19
• Vaccine Hesitancy

Interventions

• BEHAVIORAL

No Results Yet

NCT06498713 | COMPLETED | PHASE1

24 participants

Patient Controlled Administration of Liquid Acetaminophen

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-11-19

Completion:

2026-03-28

Conditions

• Pain
• Pain, Postoperative

Interventions

• DRUG
• DEVICE

No Results Yet

NCT06484621 | RECRUITING | NA

164 participants

Motivating Increases in Physical Activity for Prevention of Weight Regain After Metabolic Bariatric Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-08

Completion:

2028-09-28

Conditions

• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT06483100 | RECRUITING | PHASE2

65 participants

Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-12-20

Completion:

2032-06-30

Conditions

• Multiple Myeloma

Interventions

• DRUG
• DEVICE

No Results Yet

NCT06477471 | COMPLETED | NA

14 participants

A Clinical Study to Determine the Safety and Efficacy of An Oral Probiotic. Supplementation in Reducing the Risk of Kidney Stone in Adults With Recurrent Kidney Stone Colic or Acute Episode of Colicky Pain.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-11-29

Completion:

2025-01-07

Conditions

• Recurrent Kidney Stones With Colicky Pain

Interventions

• OTHER

No Results Yet

NCT06475989 | RECRUITING | PHASE3

264 participants

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-22

Completion:

2030-09-30

Conditions

• Refractory Differentiated Thyroid Gland Carcinoma

Interventions

• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT06469021 | COMPLETED | NA

25 participants

Effectiveness of Rehabilitation With Technology-Based Systems in Adolescent Idiopathic Scoliosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-14

Completion:

2026-03-01

Conditions

• Scoliosis; Adolescence

Interventions

• OTHER

No Results Yet

NCT06461897 | RECRUITING | PHASE3

675 participants

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-19

Completion:

2030-07-31

Conditions

• Atopic Dermatitis

Interventions

• DRUG

No Results Yet

NCT06456463 | ACTIVE_NOT_RECRUITING | PHASE2

85 participants

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-01-14

Completion:

2028-02-09

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT06450444 | RECRUITING | NA

110 participants

The RECLAIM Study.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-24

Completion:

2027-04-01

Conditions

• Chronic Migraine
• High Frequency Episodic Migraine

Interventions

• DEVICE

No Results Yet

NCT06444880 | ACTIVE_NOT_RECRUITING | PHASE2

15 participants

Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-09

Completion:

2027-07-31

Conditions

• SMARCB1-Deficient Malignancies
• Epithelioid Sarcoma
• Renal Medullary Carcinoma

Interventions

• DRUG

No Results Yet

NCT06439693 | RECRUITING | PHASE2

72 participants

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-08

Completion:

2030-03-30

Conditions

• Breast Cancer Female
• Breast Cancer
• Breast Cancer Metastatic
• Estrogen Receptor-positive Breast Cancer
• HER2-positive Breast Cancer
• Stage IV Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06431022 | COMPLETED | NA

70 participants

Web-administered STAIR for Patients on Behavioral Health Waitlists

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-11-15

Completion:

2026-06-05

Conditions

• Post Traumatic Stress Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT06429787 | RECRUITING

3574 participants

Post Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive Procedure

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2025-02-14

Completion:

2031-12-31

Conditions

• Vitamin K-Dependent Coagulation Defect
• Significant Bleeding Risk

Interventions

• DRUG

No Results Yet

NCT06421506 | RECRUITING | NA

245 participants

Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-08

Completion:

2027-09-30

Conditions

• Respiratory Distress Syndrome
• Preterm Pregnancy
• Surfactant Deficiency Syndrome Neonatal

Interventions

• PROCEDURE

No Results Yet

NCT06421155 | SUSPENDED | NA

20 participants

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-10-04

Completion:

2027-06-14

Conditions

• Acute Leukemia
• Acute Lymphoblastic Leukemia, Pediatric
• Acute Myeloid Leukemia in Children
• Myeloproliferative Neoplasm

Interventions

• OTHER

No Results Yet

NCT06417190 | RECRUITING | PHASE2

20 participants

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-01-16

Completion:

2030-12-31

Conditions

• Muscle-Invasive Bladder Carcinoma
• Tumor

Interventions

• DRUG

No Results Yet

NCT06406777 | RECRUITING | PHASE1/PHASE2

100 participants

Chronic Lung Allograft Dysfunction MRI Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-03-20

Completion:

2028-09-30

Conditions

• Chronic Lung Allograft Dysfunction Lung MRI (CLAD)

Interventions

• DIAGNOSTIC_TEST
• DRUG

No Results Yet

NCT06404242 | RECRUITING

75 participants

Plaque Characteristics Predict Recurrent Stroke in MCA Stroke Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-27

Completion:

2026-12-31

Conditions

• High Resolution Vessel Wall Imaging
• Recurrent Stroke
• Stroke, Mechanism
• Atheroscleroses, Intracranial
• Stroke, Infarct Pattern

No Results Yet

NCT06397066 | COMPLETED

384 participants

White Light Endoscopy and Magnifying Endoscopy in Assessing the Status of Hp Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-01

Completion:

2026-07-31

Conditions

• Helicobacter Pylori Infection

Interventions

• PROCEDURE

No Results Yet

NCT06386887 | RECRUITING | NA

20 participants

Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-07-11

Completion:

2026-11-30

Conditions

• Epithelial Ovarian Cancer

Interventions

• BEHAVIORAL
• DRUG

No Results Yet

NCT06373497 | RECRUITING | EARLY_PHASE1

10 participants

Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-06-19

Completion:

2026-10-31

Conditions

• Oligometastatic Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06361537 | RECRUITING | PHASE3

124 participants

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-30

Completion:

2026-12-31

Conditions

• Acute Hereditary Angio Edema

Interventions

• DRUG
• OTHER

No Results Yet

NCT06351722 | COMPLETED

100 participants

Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-25

Completion:

2025-12-15

Conditions

• Periodontitis, Adult

Interventions

• DIAGNOSTIC_TEST
• PROCEDURE

No Results Yet

NCT06347016 | ACTIVE_NOT_RECRUITING | PHASE3

311 participants

Study of Plozasiran in Adults With Severe Hypertriglyceridemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-07-23

Completion:

2026-06-17

Conditions

• Severe Hypertriglyceridemia

Interventions

• DRUG

No Results Yet

NCT06335953 | COMPLETED | NA

474 participants

ALIGN: Aligning Medications With What Matters Most (Demonstration)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-05-07

Completion:

2025-09-16

Conditions

• Polypharmacy
• Alzheimer's Disease and Related Dementias
• Mild Cognitive Impairment

Interventions

• BEHAVIORAL

Results Available