Clinical Trials

NCT05886920 | RECRUITING | PHASE1/PHASE2

67 participants

A Phase 1/2 Study of D3S-002 as Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-07-10

Completion:

2028-08-31

Conditions

• Advanced Solid Tumors With MAPK Pathway Mutations

Interventions

• DRUG

No Results Yet

NCT05879211 | ENROLLING_BY_INVITATION | NA

5000 participants

Goal Concordant Care Learning Laboratory

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-07-12

Completion:

2026-12-31

Conditions

• Cancer
• Heart Failure
• Copd
• Dementia

Interventions

• BEHAVIORAL

No Results Yet

NCT05877599 | RECRUITING | PHASE1

45 participants

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-07-12

Completion:

2029-07-31

Conditions

• Non-small Cell Lung Cancer
• Head and Neck Squamous Cell Carcinoma
• Colorectal Carcinoma
• Pancreatic Adenocarcinoma
• Breast Cancer
• Other Solid Tumors
• Ovarian Cancer
• Myeloid Neoplasms (AML/MDS)

Interventions

• BIOLOGICAL

No Results Yet

NCT05874297 | RECRUITING | NA

50 participants

Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-07-15

Completion:

2027-12-31

Conditions

• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT05870488 | ACTIVE_NOT_RECRUITING | PHASE4

110 participants

iFuse TORQ for the Treatment of Sacroiliac Joint Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-05-23

Completion:

2025-04-23

Conditions

• Sacroiliac Joint Dysfunction
• Sacroiliac; Fusion
• Sacroiliac Disorder
• Sacroiliac Joint Pain

Interventions

• DEVICE

No Results Yet

NCT05868265 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-02

Completion:

2027-06-02

Conditions

• Urothelial Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05867186 | RECRUITING

100 participants

Fit to Fight Childhood Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-20

Completion:

2027-07-31

Conditions

• Pediatric Oncology

Interventions

• BEHAVIORAL

No Results Yet

NCT05850676 | COMPLETED

54 participants

Disentangling the Role of Depression in Hypersomnia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-01

Completion:

2026-08-03

Conditions

• Hypersomnia

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05849064 | COMPLETED | NA

56 participants

Concussion Treatment in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-09-07

Completion:

2026-06-15

Conditions

• Concussion, Mild

Interventions

• BEHAVIORAL

No Results Yet

NCT05828823 | RECRUITING | NA

350 participants

Incremental Hemodialysis: The TwoPlus Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-02-26

Completion:

2030-07-31

Conditions

• End-Stage Kidney Disease

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05814354 | ACTIVE_NOT_RECRUITING | PHASE3

551 participants

SHR-A1811 Versus Investigator's Chemotherapy in Recurrent/Metastatic Breast Cancer Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-30

Completion:

2026-03-20

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05812755 | RECRUITING | PHASE4

170 participants

SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-05-19

Completion:

2028-07-31

Conditions

• Endothelial Dysfunction
• Vascular Diseases
• Kidney Injury
• Brain Disease
• Vascular Inflammation

Interventions

• DRUG

No Results Yet

NCT05812131 | RECRUITING | NA

248 participants

COPEWeb Training for Providers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-05-11

Completion:

2027-01-01

Conditions

• PTSD
• Substance Use Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT05789251 | COMPLETED | NA

54 participants

Assess the Possibility of Diagnosing Diabetes and Rediabetes Following Oral Induced Hyperglycemia in Patients With Dunnigan's Partial Familial Lipodystrophy by Replacing 75 g of Glucose With a Standardized Carbohydrate Breakfast and Continuous Interstitial Monitoring Glucose)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-19

Completion:

2026-01-01

Conditions

• Lipodystrophy

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05785845 | COMPLETED | NA

17 participants

Computed Tomography-Guided Stereotactic Adaptive Radiotherapy (CT-STAR) for the Treatment of Central and Ultra-Central Early-Stage Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-04-10

Completion:

2026-06-02

Conditions

• Early Stage Non-small Cell Lung Cancer
• Non-small Cell Lung Cancer

Interventions

• RADIATION
• DEVICE

No Results Yet

NCT05775588 | COMPLETED | NA

22 participants

Long-term Effects of Endobronchial Valve Implantation on Cardiac Function and Skeletal Muscle Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-27

Completion:

2024-12-31

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

• PROCEDURE

No Results Yet

NCT05770479 | ENROLLING_BY_INVITATION | NA

28 participants

Assessing and Improving the Durability of Compensatory Cognitive Training for Older Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-07-01

Completion:

2028-06-30

Conditions

• Mild Cognitive Impairment

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05758896 | COMPLETED | PHASE2

218 participants

Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-12-27

Completion:

2026-07-22

Conditions

• Contrast Induced Acute Kidney Injury

Interventions

• DRUG

No Results Yet

NCT05755061 | ACTIVE_NOT_RECRUITING | PHASE1

31 participants

WEBCAMS: Walking Exercise for Brain and Cognition in Adults With Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-02-01

Completion:

2025-02-28

Conditions

• Multiple Sclerosis
• Relapsing-remitting Multiple Sclerosis

Interventions

• BEHAVIORAL

No Results Yet

NCT05753501 | ACTIVE_NOT_RECRUITING | PHASE1

135 participants

Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-09

Completion:

2031-03-31

Conditions

• Hematologic Cancer

Interventions

• DRUG

No Results Yet

NCT05752084 | COMPLETED

250 participants

Bilirubin Increases the Risk of Nosocomial Infection in Cirrhotic Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2022-01-01

Completion:

2022-11-01

Conditions

• Nosocomial Infection

No Results Yet

NCT05750862 | COMPLETED | NA

30 participants

Accuracy of Topography Guided Automatic Marking of the Intraocular Lens (IOL) -Axis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-20

Completion:

2024-09-30

Conditions

• Cataract Senile
• Astigmatism

Interventions

• PROCEDURE

No Results Yet

NCT05746546 | COMPLETED | PHASE2

25 participants

Depressed Mood Improvement Through Nicotine Dosing-3 (Depressed MIND3) Extension

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-04-15

Completion:

2026-07-09

Conditions

• Depressive Disorder

Interventions

• DRUG

No Results Yet

NCT05746273 | COMPLETED | PHASE2

40 participants

Depressed Mood Improvement Through Nicotine Dosing 3

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-04-15

Completion:

2026-07-09

Conditions

• Depressive Disorder

Interventions

• DRUG

No Results Yet

NCT05739162 | ACTIVE_NOT_RECRUITING | NA

2 participants

A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-09-20

Completion:

2025-07-01

Conditions

• Obesity
• Ulcerative Colitis

Interventions

• DEVICE
• BEHAVIORAL

Results Available

NCT05732675 | COMPLETED | NA

167 participants

Skills to Empower Affirmative Men

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-09-01

Completion:

2025-03-01

Conditions

• Bisexuality
• Homosexuality
• HIV Infections

Interventions

• BEHAVIORAL

Results Available

NCT05731141 | RECRUITING

1200 participants

A Prospective Natural History Study of Lymphatic Anomalies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-20

Completion:

2026-12-31

Conditions

• Lymphatic Diseases
• Lymphatic Abnormalities

No Results Yet

NCT05729581 | ACTIVE_NOT_RECRUITING | NA

429 participants

Effectiveness of Educational Intervention on Sustainable Breastfeeding: The GREEN MOTHER Project

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2022-04-11

Completion:

2025-10-15

Conditions

• Healthy Diet
• Health Behaviour
• Environmental-Pollution-Related Condition
• Mothers
• Child, Only

Interventions

• BEHAVIORAL

No Results Yet

NCT05725421 | NOT_YET_RECRUITING | NA

5 participants

Transplantation of Reconstructed Renal Allografts Following Ex-Vivo Partial Nephrectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-30

Completion:

2027-06-30

Conditions

• Renal Cell Carcinoma

Interventions

• PROCEDURE

No Results Yet

NCT05724199 | COMPLETED | PHASE3

746 participants

A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-02-21

Completion:

2024-09-15

Conditions

• Atopic Dermatitis

Interventions

• DRUG
• OTHER

Results Available

NCT05721248 | ACTIVE_NOT_RECRUITING | PHASE2

82 participants

STOP-HER2: Stopping Trastuzumab in HER2+ MBC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-04-19

Completion:

2026-06-22

Conditions

• Breast Cancer
• Metastatic Breast Cancer
• HER2-positive Breast Cancer

Interventions

• OTHER

No Results Yet

NCT05700617 | RECRUITING | EARLY_PHASE1

5 participants

Cardiac Power Output in Cardiogenic Shock Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-07-06

Completion:

2027-12-31

Conditions

• Heart Failure
• Cardiogenic Shock

Interventions

• DRUG

No Results Yet

NCT05700201 | RECRUITING | NA

216 participants

Investigating Cardiac Health of Adults With Trauma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-04-21

Completion:

2026-08-31

Conditions

• Posttraumatic Stress Disorder

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05699642 | COMPLETED | PHASE2

70 participants

Online Tai Chi Plus Fitbit After ACS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-27

Completion:

2026-07-01

Conditions

• Acute Coronary Syndrome
• Physical Inactivity

Interventions

• BEHAVIORAL

No Results Yet

NCT05682859 | COMPLETED | PHASE4

41 participants

Treatment of Chronic Hand Eczema With Oral Roflumilast (HERO)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-09-25

Completion:

2025-06-17

Conditions

• Chronic Hand Eczema

Interventions

• DRUG

No Results Yet

NCT05650710 | COMPLETED | NA

51 participants

Intraoperative Ansa Cervicalis Nerve (ACN) Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-02-28

Completion:

2025-10-20

Conditions

• Head and Neck Cancer
• Obstructive Sleep Apnea

Interventions

• DEVICE

No Results Yet

NCT05636020 | ACTIVE_NOT_RECRUITING | NA

85 participants

Intervention to Change Affect Recognition and Empathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-15

Completion:

2027-02-28

Conditions

• Traumatic Brain Injury
• Concussion, Intermediate
• Concussion, Severe
• Concussion With LOC 31 to 59 Minutes
• Concussion With Brief Loss of Consciousness
• Traumatic Brain Injury With Brief Loss of Consciousness
• Traumatic Brain Injury With Loss of Consciousness
• Traumatic Brain Injury With Prolonged Loss of Consciousness
• Traumatic Brain Injury (TBI); Concussion, Initial Encounter
• Traumatic Brain Injury (TBI); Concussion, Subsequent Encounter
• Traumatic Brain Injury With No Loss of Consciousness
• Traumatic Brain Injury With Open Intracranial Wound
• Traumatic Brain Injury With Moderate Loss of Consciousness

Interventions

• BEHAVIORAL

No Results Yet

NCT05627674 | ENROLLING_BY_INVITATION | NA

915 participants

Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-01-01

Completion:

2027-08-31

Conditions

• Smoking
• Smoking Cessation
• Tobacco Use Cessation

Interventions

• BEHAVIORAL

No Results Yet

NCT05619913 | COMPLETED | PHASE2

13 participants

EPOCH: Eribulin and Pembrolizumab in Ovarian/Uterine Carcinosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-05-22

Completion:

2025-03-31

Conditions

• Ovarian Carcinosarcoma
• Uterine Carcinosarcoma

Interventions

• DRUG

No Results Yet

NCT05610852 | RECRUITING | NA

276 participants

Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-01

Completion:

2026-12-01

Conditions

• Prostate Adenocarcinoma
• Prostate Cancer

Interventions

• PROCEDURE

No Results Yet