Clinical Trials

NCT05788536 | RECRUITING | PHASE1/PHASE2

36 participants

A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-27

Completion:

2029-02-26

Conditions

• Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)

Interventions

• GENETIC

No Results Yet

NCT05771675 | RECRUITING | EARLY_PHASE1

90 participants

Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-10-24

Completion:

2027-12-31

Conditions

• Recurrent Acute Pancreatitis
• Chronic Pancreatitis

Interventions

• DRUG

No Results Yet

NCT05732116 | COMPLETED

356 participants

PTSD of Surgeons or Anesthesiologists on Prognosis of Surgical Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2023-02-21

Completion:

2025-12-31

Conditions

• Post Traumatic Stress Disorder
• Postoperative Complications
• COVID-19

Interventions

• OTHER

No Results Yet

NCT05720065 | RECRUITING | PHASE2

100 participants

Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-11-14

Completion:

2027-08-31

Conditions

• Temporomandibular Disorders

Interventions

• DRUG

No Results Yet

NCT05715242 | COMPLETED | NA

32 participants

Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-12-05

Completion:

2024-04-09

Conditions

• Obesity
• Overweight
• Weight Loss
• Health Behavior

Interventions

• BEHAVIORAL

Results Available

NCT05708352 | RECRUITING | PHASE2

170 participants

A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-27

Completion:

2028-09-30

Conditions

• Glioblastoma Multiforme

Interventions

• BEHAVIORAL

No Results Yet

NCT05701800 | TERMINATED | PHASE1

659 participants

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of Age

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-01-23

Completion:

2025-12-31

Conditions

• Herpes Zoster

Interventions

• BIOLOGICAL

No Results Yet

NCT05676203 | ACTIVE_NOT_RECRUITING | PHASE3

250 participants

A Trial Comparing Docetaxel 75 mg/m2 (3w) Versus Docetaxel 50 mg/m2 (2w) in Combination With Darolutamide + ADT in mHSPC Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-05-16

Completion:

2025-07-03

Conditions

• Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Interventions

• DRUG

No Results Yet

NCT05668871 | COMPLETED | PHASE4

326 participants

A Study of Danning Tablet in Patients With Polypoid Lesions of Gallbladder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-12-01

Completion:

2026-02-25

Conditions

• Multiple Gallbladder Polyps

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT05664880 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

24 participants

A PiLot ClinicaL TrIal of ParicAlcitol for ChroNiC PancrEatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-01

Completion:

2027-07-31

Conditions

• Chronic Pancreatitis

Interventions

• DRUG

No Results Yet

NCT05654922 | RECRUITING | PHASE3

100 participants

Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-04-10

Completion:

2028-02-29

Conditions

• Pre-Bronchiolitis Obliterans Syndrome

Interventions

• DRUG
• OTHER

No Results Yet

NCT05647265 | RECRUITING | PHASE2

26 participants

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-11-27

Completion:

2026-12-15

Conditions

• Pleural Biphasic Mesothelioma
• Pleural Sarcomatoid Mesothelioma

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT05639894 | COMPLETED | PHASE1/PHASE2

865 participants

Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-11-17

Completion:

2025-05-02

Conditions

• Respiratory Syncytial Virus Immunization

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT05596539 | RECRUITING

200 participants

Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2023-03-22

Completion:

2026-09-30

Conditions

• Hypophosphatasia

Interventions

• OTHER

No Results Yet

NCT05591820 | RECRUITING | NA

93 participants

A Randomized Controlled Trial on Brief Behavioral Parent Training

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-10-17

Completion:

2026-11-30

Conditions

• Disruptive Behavior
• Behavior Problems
• Behavioral Problems
• Problem Behaviors
• Behavioral Symptoms
• Behavioral Difficulties

Interventions

• BEHAVIORAL

No Results Yet

NCT05590494 | RECRUITING | NA

15 participants

Novel Treatment for Rotator Cuff Tears

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-11-07

Completion:

2028-12-31

Conditions

• Supraspinatus Tear

Interventions

• PROCEDURE

No Results Yet

NCT05581498 | WITHDRAWN | NA

0 participants

Glaucoma Exercise as Medicine Study (GEMS).

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2026-06-30

Completion:

2028-12-31

Conditions

• Glaucoma

Interventions

• BEHAVIORAL

No Results Yet

NCT05577962 | RECRUITING | PHASE4

160 participants

Opioid Free Anesthesia on the Quality of Early Recovery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-08-01

Completion:

2026-10-01

Conditions

• Opioid-free Anesthesia

Interventions

• DRUG

No Results Yet

NCT05556746 | ACTIVE_NOT_RECRUITING | PHASE2

94 participants

Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible Tuberculosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-11-24

Completion:

2025-06-12

Conditions

• Tuberculosis, Pulmonary
• HIV

Interventions

• DRUG

Results Available

NCT05551858 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

32 participants

Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-11-17

Completion:

2030-06-30

Conditions

• Safety Issues
• Pain
• Pancreas Fibrosis

Interventions

• DRUG

No Results Yet

NCT05539079 | RECRUITING

2000 participants

A Prospective Long-term Observational Study in Patients With Monoclonal Gammopathy of Undetermined Significance

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2023-09-06

Completion:

2030-12-01

Conditions

• MGUS

No Results Yet

NCT05537025 | COMPLETED | PHASE1/PHASE2

105 participants

Study of ARO-MMP7 Inhalation Solution in Healthy Participants and Participants With Idiopathic Pulmonary Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-01-30

Completion:

2025-09-05

Conditions

• Idiopathic Pulmonary Fibrosis

Interventions

• DRUG

Results Available

NCT05507879 | RECRUITING

200 participants

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2022-09-26

Completion:

2030-07-01

Conditions

• Breast Carcinoma
• Cardiomyopathy
• Congestive Heart Failure

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05499507 | ACTIVE_NOT_RECRUITING | NA

345 participants

The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-01-24

Completion:

2027-07-15

Conditions

• Pregnancy Related
• Hypertension
• Obesity
• Racism

Interventions

• BEHAVIORAL

No Results Yet

NCT05477277 | RECRUITING | NA

100 participants

Adverse Outcomes and Mortality in Liver Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-11-02

Completion:

2026-12-31

Conditions

• End Stage Liver DIsease
• Sarcopenia
• Sarcopenic Obesity
• Cirrhosis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05473507 | ACTIVE_NOT_RECRUITING

26 participants

A Study of Observation and Follow-up in People With Basal Cell Carcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2022-07-27

Completion:

2027-07-31

Conditions

• Basal Cell Carcinoma

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05458284 | ACTIVE_NOT_RECRUITING | PHASE2

80 participants

The Effect of Acupuncture on Nerve Pain Caused by Taxane (Chemotherapy) Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-07-11

Completion:

2027-07-31

Conditions

• Breast Cancer
• Taxane-Induced Peripheral Neuropathy

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05444465 | RECRUITING | NA

234 participants

Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-08-30

Completion:

2026-08-15

Conditions

• Rotator Cuff Injuries

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT05435547 | RECRUITING | PHASE4

76 participants

Preoperative Corticosteroids in Autoimmune Thyroid Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-06-16

Completion:

2026-12-30

Conditions

• Graves Disease
• Hashimoto Disease

Interventions

• DRUG

No Results Yet

NCT05431192 | ACTIVE_NOT_RECRUITING | NA

176 participants

Mind Your Heart-II

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-11-30

Completion:

2026-07-31

Conditions

• Heart Failure
• Cognitive Impairment

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05395325 | COMPLETED | NA

27 participants

Clinical Effects of Combined Kinesiotaping and Steroid Injection in Stroke Patients With Hemiplegic Shoulder Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-05-05

Completion:

2024-07-31

Conditions

• Stroke
• Hemiplegic Shoulder Pain

Interventions

• OTHER

No Results Yet

NCT05334316 | COMPLETED | PHASE2

24 participants

Individualizing Corticosteroid Use in Pneumonia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-11-06

Completion:

2026-04-03

Conditions

• Pneumonia

Interventions

• DRUG

No Results Yet

NCT05321628 | COMPLETED | NA

401 participants

Evaluating Clinical Routines for ICBT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-12-03

Completion:

2024-10-03

Conditions

• Depression
• Panic Disorder
• Social Anxiety Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05318469 | RECRUITING | PHASE1/PHASE2

34 participants

Ivermectin in Combination With Balstilimab or Pembrolizumab in Patients With Metastatic Triple Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-10-13

Completion:

2026-10-31

Conditions

• Anatomic Stage IV Breast Cancer AJCC v8
• Metastatic Triple-Negative Breast Carcinoma

Interventions

• DRUG

No Results Yet

NCT05309655 | ACTIVE_NOT_RECRUITING | NA

90 participants

Cardiac Outcomes With Near-Complete Estrogen Deprivation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-09-02

Completion:

2028-05-01

Conditions

• Breast Cancer
• Triple Negative Breast Cancer
• Cardiovascular Complications

Interventions

• DRUG
• DIAGNOSTIC_TEST
• OTHER
• BEHAVIORAL

No Results Yet

NCT05296447 | ENROLLING_BY_INVITATION | PHASE2

100 participants

Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With and Without Diabetic Retinopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-04

Completion:

2031-06-30

Conditions

• Diabetic Retinopathy, DR

Interventions

• DRUG

No Results Yet

NCT05294991 | ACTIVE_NOT_RECRUITING | NA

276 participants

Wellness App for Sleep Disturbance in Hematological Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-02-20

Completion:

2026-12-20

Conditions

• Cancer
• Sleep Disturbance
• Anxiety
• Depression
• Inflammation
• Fatigue

Interventions

• BEHAVIORAL

No Results Yet

NCT05267340 | COMPLETED | NA

120 participants

Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-02-08

Completion:

2025-12-11

Conditions

• Depression Mild
• Depression Moderate
• Depression, Teen

Interventions

• BEHAVIORAL

No Results Yet

NCT05258305 | COMPLETED | NA

200 participants

AuraClens™ System in Processing of Lipoaspirate for Autologous Fat Grafting to the Breast

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-05-05

Completion:

2025-01-08

Conditions

• Breast Fat Grafting Retention

Interventions

• DEVICE

Results Available

NCT05256537 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Fludarabine and Total Body Irradiation 800 Centigray (cGy) or 1125 cGy For Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-26

Completion:

2024-09-20

Conditions

• Hematologic Neoplasms

Interventions

• OTHER

No Results Yet