Clinical Trials

NCT05249556 | NOT_YET_RECRUITING | PHASE3

20 participants

Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2027-03-31

Completion:

2029-12-31

Conditions

• CDKL5 Deficiency Disorder

Interventions

• DRUG

No Results Yet

NCT05235074 | COMPLETED | PHASE1/PHASE2

40 participants

OH2 Oncolytic Viral Therapy in Central Nervous System Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-16

Completion:

2026-07-23

Conditions

• Central Nervous System Tumors

Interventions

• BIOLOGICAL

No Results Yet

NCT05215106 | ACTIVE_NOT_RECRUITING | PHASE2

200 participants

Short-term Pre-OPerative Durvalumab (MEDI 4736) in Early Small Triple Negative Breast Cancer Patients (POP-Durva)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-12-06

Completion:

2026-08-15

Conditions

• Early Small (cT1N0) Triple Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05210803 | ENROLLING_BY_INVITATION | PHASE2

116 participants

Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-12-20

Completion:

2031-07-31

Conditions

• Neovascular Age-Related Macular Degeneration (nAMD)

Interventions

• DRUG

No Results Yet

NCT05199441 | COMPLETED | PHASE4

226 participants

Efficacy of Galeo® in Patients With Postprandial Distress Syndrome Subtype in Functional Dyspepsia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-02-25

Completion:

2023-07-05

Conditions

• Dyspepsia

Interventions

• DRUG

No Results Yet

NCT05176483 | RECRUITING | PHASE1

1394 participants

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-12-14

Completion:

2027-01-31

Conditions

• Renal Cell Carcinoma (RCC)
• Metastatic Castration-Resistant Prostate Cancer (mCRPC)
• Urothelial Carcinoma (UC)
• Solid Tumor
• Hepatocellular Carcinoma (HCC)
• Non-small Cell Lung Cancer (NSCLC)
• Colorectal Cancer (CRC)
• Head and Neck Squamous Cell Carcinoma (HNSCC)
• Clear Cell Renal Cell Carcinoma (ccRCC)
• Non-Clear Cell Renal Cell Carcinoma (nccRCC)
• Drug-Drug Interaction (DDI)

Interventions

• DRUG

No Results Yet

NCT05171647 | ACTIVE_NOT_RECRUITING | PHASE3

208 participants

A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-25

Completion:

2025-02-17

Conditions

• Non-Hodgkin Lymphoma

Interventions

• DRUG

Results Available

NCT05170204 | ACTIVE_NOT_RECRUITING | PHASE3

68 participants

A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-11-01

Completion:

2030-06-16

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05144542 | ACTIVE_NOT_RECRUITING | NA

135 participants

Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-03-07

Completion:

2025-10-17

Conditions

• Lung Carcinoma

Interventions

• DRUG

Results Available

NCT05134454 | ACTIVE_NOT_RECRUITING | NA

3300 participants

Atrial Fibrillation Screening Post Ischemic Cerebrovascular Events

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-01-20

Completion:

2025-12-31

Conditions

• Ischemic Stroke
• TIA

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05087745 | RECRUITING | EARLY_PHASE1

50 participants

A Clinical Study on TIL for the Treatment of Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-12-10

Completion:

2027-12-10

Conditions

• Advanced Solid Tumor
• Tumor Infiltrating Lymphocytes
• Treatment Side Effects
• Effects of Immunotherapy

Interventions

• BIOLOGICAL

No Results Yet

NCT05086900 | COMPLETED

283 participants

Developing a PROM for Recurrent Urinary Tract Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-01

Completion:

2021-09-01

Conditions

• Urologic Diseases
• Patient Satisfaction
• Pain, Chronic
• Sexual Dysfunction

Interventions

• OTHER

Results Available

NCT04999761 | RECRUITING | PHASE1

917 participants

AB122 Platform Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-06-01

Completion:

2027-06-30

Conditions

• Advanced or Metastatic Solid Tumor
• Pancreatic Ductal Adenocarcinoma
• Colorectal Cancer
• Non-small Cell Lung Cancer
• Gastric Cancer
• Alveolar Soft Part Sarcoma
• Esophageal Cancer
• Head and Neck Cancer
• Biliary Tract Cancer

Interventions

• DRUG

No Results Yet

NCT04967833 | RECRUITING | EARLY_PHASE1

20 participants

A Study of GC101 TIL in Advanced Solid Tumors (TR)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-22

Completion:

2027-12-22

Conditions

• Advanced Solid Tumors

Interventions

• BIOLOGICAL

No Results Yet

NCT04960072 | RECRUITING | EARLY_PHASE1

50 participants

A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-06-30

Completion:

2027-12-30

Conditions

• Gastrointestinal Tumor

Interventions

• BIOLOGICAL

No Results Yet

NCT04943913 | RECRUITING | EARLY_PHASE1

50 participants

Study of GC101 TIL in Brain Glioma (Soochow2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-06

Completion:

2026-12-30

Conditions

• Glioma

Interventions

• BIOLOGICAL

No Results Yet

NCT04929236 | RECRUITING | PHASE3

30 participants

Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-10-01

Completion:

2028-12-31

Conditions

• Pediatric Chronic Inflammatory Demyelinating Polyneuropathy

Interventions

• DRUG

No Results Yet

NCT04923555 | COMPLETED | NA

33 participants

Analysis of the Postprandial Effects of a Vegetable Protein Mixture Rich in Arginine, Cysteine and Leucine on Endothelial Dysfunction and Inflammation at Low Noise in Elderly People With Cardiometabolic Risk

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-09

Completion:

2022-06-07

Conditions

• Metabolic Syndrome
• Predisposition to Cardiovascular Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT04919122 | ACTIVE_NOT_RECRUITING

468 participants

Outcomes Database to prospectivelY aSSEss the Changing TherapY Landscape in Renal Cell Carcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-01

Completion:

2026-12-31

Conditions

• Metastatic Renal Cell Carcinoma

No Results Yet

NCT04906096 | RECRUITING | PHASE2

25 participants

Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-06-01

Completion:

2026-12-01

Conditions

• Primary Central Nervous System Lymphoma
• Non-Hodgkin Lymphoma of Extranodal Site

Interventions

• DRUG

No Results Yet

NCT04900623 | RECRUITING | PHASE2

145 participants

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-07-02

Completion:

2030-06-01

Conditions

• HPV-Associated Oropharyngeal Squamous Cell Carcinoma
• HPV Positive Oropharyngeal Squamous Cell Carcinoma
• HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage
• HPV-Related Squamous Cell Carcinoma
• Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage
• HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Pathologic Stage

Interventions

• DEVICE
• RADIATION
• DRUG

No Results Yet

NCT04892823 | RECRUITING

110 participants

Social Relationships and Accelerated Aging in Hematopoietic Cell Transplant Survivors

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-18

Completion:

2027-07-16

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04891640 | COMPLETED | PHASE4

164 participants

Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-11

Completion:

2026-06-01

Conditions

• Juvenile Spondyloarthritis

Interventions

• OTHER

No Results Yet

NCT04889911 | COMPLETED | NA

17 participants

Pilot RCT of Self-stigma Treatment for First Episode Psychosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-08-01

Completion:

2025-10-27

Conditions

• First Episode Psychosis
• Youth

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04855305 | COMPLETED | PHASE2

47 participants

Optimizing and Standardizing 129Xe Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-12

Completion:

2025-06-11

Conditions

• Interstitial Lung Diseases

Interventions

• DRUG

Results Available

NCT04851288 | COMPLETED | PHASE2

112 participants

Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-02

Completion:

2025-12-01

Conditions

• Aging

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04840563 | COMPLETED | NA

10 participants

Surface Refractive Index Shift of Kalifilcon A Compared With Dailies Total1 and Precision1 Lenses

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-07

Completion:

2021-04-15

Conditions

• Contact Lens Wear

Interventions

• DEVICE

Results Available

NCT04833790 | COMPLETED | NA

2451 participants

What Drives Poor Care for Child Diarrhea: A Standardized Patient Experiment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-05-05

Completion:

2022-12-31

Conditions

• Child Diarrhea

Interventions

• BEHAVIORAL

Results Available

NCT04827862 | COMPLETED | PHASE2

6 participants

RADVAX™ for Relapsed/Refractory Non-Hodgkin Lymphoma: A Phase II Trial of Pembrolizumab + Low Dose Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-07-01

Completion:

2026-05-01

Conditions

• Non Hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT04810871 | SUSPENDED | NA

40 participants

Surgical Resection of Latent Brain Tumors Prior to Recurrence

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-06

Completion:

2028-03-01

Conditions

• Brain Neoplasm

Interventions

• PROCEDURE

No Results Yet

NCT04794075 | RECRUITING | NA

300 participants

Therapeutic Education and Nursing Support Program for Supportive Care, in Patients Treated With Hormone Therapy for Non-metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-08-09

Completion:

2028-08-31

Conditions

• Neoplasm of Breast

Interventions

• OTHER

No Results Yet

NCT04788836 | COMPLETED

61 participants

How Altered Gut-Brain-Axis Influences Food Choices: Part 2 (BrainFood)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-01

Completion:

2025-12-31

Conditions

• Food Preferences
• Obesity

Interventions

• OTHER

No Results Yet

NCT04743401 | COMPLETED | NA

54 participants

Feasibility of a Tele-game-based Exercise (Tele-exergame) Program to Prevent Deconditioning in Hospitalized COVID-19 Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-07-05

Completion:

2023-12-31

Conditions

• COVID 19
• Rehabilitation
• Inpatient
• Hospitalized

Interventions

• OTHER

Results Available

NCT04739189 | COMPLETED | NA

20 participants

Appetite Response to Exercise- Versus Energy Restriction-induced Energy Deficit in Adolescents With Obesity.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-08-28

Completion:

2021-10-03

Conditions

• Pediatric Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT04730479 | COMPLETED

330 participants

Echography to Predict Radial Artery Catheterization Failure (EPRAC)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-15

Completion:

2022-04-06

Conditions

• Cardiac and Aortic Surgery

No Results Yet

NCT04729933 | ACTIVE_NOT_RECRUITING | NA

16 participants

Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-03-11

Completion:

2025-01-03

Conditions

• Heart Failure
• Mitral Regurgitation

Interventions

• DEVICE

Results Available

NCT04713982 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

30 participants

Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-19

Completion:

2027-06-30

Conditions

• Huntington Disease

Interventions

• DRUG

No Results Yet

NCT04651504 | COMPLETED | NA

185903 participants

Rural Colon Cancer Screening Toolkit Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-12-02

Completion:

2024-12-31

Conditions

• Colon Cancer Screening

Interventions

• OTHER

Results Available

NCT04649086 | TERMINATED | NA

60 participants

Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-06-05

Completion:

2022-01-07

Conditions

• Covid19
• Sarcopenia
• Muscle Weakness

Interventions

• OTHER

No Results Yet

NCT04624581 | COMPLETED | NA

260 participants

FIbromyalgia anD GenetIcs Subgroups (FIDGIS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-11-30

Completion:

2022-01-17

Conditions

• Fibromyalgia

Interventions

• DEVICE

No Results Yet