Clinical Trials

NCT05176483 | RECRUITING | PHASE1

1394 participants

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-12-14

Completion:

2027-01-31

Conditions

• Renal Cell Carcinoma (RCC)
• Metastatic Castration-Resistant Prostate Cancer (mCRPC)
• Urothelial Carcinoma (UC)
• Solid Tumor
• Hepatocellular Carcinoma (HCC)
• Non-small Cell Lung Cancer (NSCLC)
• Colorectal Cancer (CRC)
• Head and Neck Squamous Cell Carcinoma (HNSCC)
• Clear Cell Renal Cell Carcinoma (ccRCC)
• Non-Clear Cell Renal Cell Carcinoma (nccRCC)
• Drug-Drug Interaction (DDI)

Interventions

• DRUG

No Results Yet

NCT05171647 | ACTIVE_NOT_RECRUITING | PHASE3

208 participants

A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-25

Completion:

2025-02-17

Conditions

• Non-Hodgkin Lymphoma

Interventions

• DRUG

Results Available

NCT05170204 | ACTIVE_NOT_RECRUITING | PHASE3

68 participants

A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-11-01

Completion:

2030-06-16

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05144542 | ACTIVE_NOT_RECRUITING | NA

135 participants

Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-03-07

Completion:

2025-10-17

Conditions

• Lung Carcinoma

Interventions

• DRUG

Results Available

NCT05134454 | ACTIVE_NOT_RECRUITING | NA

3300 participants

Atrial Fibrillation Screening Post Ischemic Cerebrovascular Events

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-01-20

Completion:

2025-12-31

Conditions

• Ischemic Stroke
• TIA

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05091424 | RECRUITING | PHASE1

332 participants

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-03-07

Completion:

2031-02-10

Conditions

• Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Interventions

• DRUG

No Results Yet

NCT05087745 | RECRUITING | EARLY_PHASE1

50 participants

A Clinical Study on TIL for the Treatment of Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-12-10

Completion:

2027-12-10

Conditions

• Advanced Solid Tumor
• Tumor Infiltrating Lymphocytes
• Treatment Side Effects
• Effects of Immunotherapy

Interventions

• BIOLOGICAL

No Results Yet

NCT05086900 | COMPLETED

283 participants

Developing a PROM for Recurrent Urinary Tract Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-01

Completion:

2021-09-01

Conditions

• Urologic Diseases
• Patient Satisfaction
• Pain, Chronic
• Sexual Dysfunction

Interventions

• OTHER

Results Available

NCT05039619 | RECRUITING | PHASE2

40 participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-05-12

Completion:

2028-06-15

Conditions

• Lupus Nephritis

Interventions

• DRUG

No Results Yet

NCT05008848 | RECRUITING | PHASE3

600 participants

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-01

Completion:

2027-03-01

Conditions

• Cigarette Smoking-Related Carcinoma

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04999761 | RECRUITING | PHASE1

917 participants

AB122 Platform Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-06-01

Completion:

2027-06-30

Conditions

• Advanced or Metastatic Solid Tumor
• Pancreatic Ductal Adenocarcinoma
• Colorectal Cancer
• Non-small Cell Lung Cancer
• Gastric Cancer
• Alveolar Soft Part Sarcoma
• Esophageal Cancer
• Head and Neck Cancer
• Biliary Tract Cancer

Interventions

• DRUG

No Results Yet

NCT04967833 | RECRUITING | EARLY_PHASE1

20 participants

A Study of GC101 TIL in Advanced Solid Tumors (TR)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-22

Completion:

2027-12-22

Conditions

• Advanced Solid Tumors

Interventions

• BIOLOGICAL

No Results Yet

NCT04960072 | RECRUITING | EARLY_PHASE1

50 participants

A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-06-30

Completion:

2027-12-30

Conditions

• Gastrointestinal Tumor

Interventions

• BIOLOGICAL

No Results Yet

NCT04943913 | RECRUITING | EARLY_PHASE1

50 participants

Study of GC101 TIL in Brain Glioma (Soochow2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-06

Completion:

2026-12-30

Conditions

• Glioma

Interventions

• BIOLOGICAL

No Results Yet

NCT04929236 | RECRUITING | PHASE3

30 participants

Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-10-01

Completion:

2028-12-31

Conditions

• Pediatric Chronic Inflammatory Demyelinating Polyneuropathy

Interventions

• DRUG

No Results Yet

NCT04929041 | SUSPENDED | PHASE2/PHASE3

427 participants

Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-10-07

Completion:

2030-12-12

Conditions

• Lung Adenocarcinoma
• Lung Adenosquamous Carcinoma
• Lung Non-Small Cell Carcinoma
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8

Interventions

• PROCEDURE
• BIOLOGICAL
• OTHER
• RADIATION

No Results Yet

NCT04923555 | COMPLETED | NA

33 participants

Analysis of the Postprandial Effects of a Vegetable Protein Mixture Rich in Arginine, Cysteine and Leucine on Endothelial Dysfunction and Inflammation at Low Noise in Elderly People With Cardiometabolic Risk

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-09

Completion:

2022-06-07

Conditions

• Metabolic Syndrome
• Predisposition to Cardiovascular Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT04919122 | ACTIVE_NOT_RECRUITING

468 participants

Outcomes Database to prospectivelY aSSEss the Changing TherapY Landscape in Renal Cell Carcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2022-04-01

Completion:

2026-12-31

Conditions

• Metastatic Renal Cell Carcinoma

No Results Yet

NCT04906096 | RECRUITING | PHASE2

25 participants

Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-06-01

Completion:

2026-12-01

Conditions

• Primary Central Nervous System Lymphoma
• Non-Hodgkin Lymphoma of Extranodal Site

Interventions

• DRUG

No Results Yet

NCT04900623 | RECRUITING | PHASE2

145 participants

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-07-02

Completion:

2030-06-01

Conditions

• HPV-Associated Oropharyngeal Squamous Cell Carcinoma
• HPV Positive Oropharyngeal Squamous Cell Carcinoma
• HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage
• HPV-Related Squamous Cell Carcinoma
• Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage
• HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Pathologic Stage

Interventions

• DEVICE
• RADIATION
• DRUG

No Results Yet

NCT04892823 | RECRUITING

110 participants

Social Relationships and Accelerated Aging in Hematopoietic Cell Transplant Survivors

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-18

Completion:

2027-07-16

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04891640 | COMPLETED | PHASE4

164 participants

Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-11

Completion:

2026-06-01

Conditions

• Juvenile Spondyloarthritis

Interventions

• OTHER

No Results Yet

NCT04889911 | COMPLETED | NA

17 participants

Pilot RCT of Self-stigma Treatment for First Episode Psychosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2023-08-01

Completion:

2025-10-27

Conditions

• First Episode Psychosis
• Youth

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04855305 | COMPLETED | PHASE2

47 participants

Optimizing and Standardizing 129Xe Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-12

Completion:

2025-06-11

Conditions

• Interstitial Lung Diseases

Interventions

• DRUG

Results Available

NCT04851288 | COMPLETED | PHASE2

112 participants

Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-02

Completion:

2025-12-01

Conditions

• Aging

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04840563 | COMPLETED | NA

10 participants

Surface Refractive Index Shift of Kalifilcon A Compared With Dailies Total1 and Precision1 Lenses

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-07

Completion:

2021-04-15

Conditions

• Contact Lens Wear

Interventions

• DEVICE

Results Available

NCT04833790 | COMPLETED | NA

2451 participants

What Drives Poor Care for Child Diarrhea: A Standardized Patient Experiment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-05-05

Completion:

2022-12-31

Conditions

• Child Diarrhea

Interventions

• BEHAVIORAL

Results Available

NCT04827862 | COMPLETED | PHASE2

6 participants

RADVAX™ for Relapsed/Refractory Non-Hodgkin Lymphoma: A Phase II Trial of Pembrolizumab + Low Dose Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2022-07-01

Completion:

2026-05-01

Conditions

• Non Hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT04810871 | SUSPENDED | NA

40 participants

Surgical Resection of Latent Brain Tumors Prior to Recurrence

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-05-06

Completion:

2028-03-01

Conditions

• Brain Neoplasm

Interventions

• PROCEDURE

No Results Yet

NCT04803201 | SUSPENDED | PHASE2

170 participants

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-10-08

Completion:

2027-05-19

Conditions

• Angioimmunoblastic T-cell Lymphoma
• Enteropathy-Associated T-Cell Lymphoma
• Follicular T-Cell Lymphoma
• Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
• Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma
• Nodal Peripheral T-Cell Lymphoma With TFH Phenotype
• Peripheral T-Cell Lymphoma, Not Otherwise Specified

Interventions

• DRUG

No Results Yet

NCT04802759 | RECRUITING | PHASE1/PHASE2

316 participants

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-06-22

Completion:

2029-05-30

Conditions

• Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04794075 | RECRUITING | NA

300 participants

Therapeutic Education and Nursing Support Program for Supportive Care, in Patients Treated With Hormone Therapy for Non-metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-08-09

Completion:

2028-08-31

Conditions

• Neoplasm of Breast

Interventions

• OTHER

No Results Yet

NCT04788836 | COMPLETED

61 participants

How Altered Gut-Brain-Axis Influences Food Choices: Part 2 (BrainFood)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-01

Completion:

2025-12-31

Conditions

• Food Preferences
• Obesity

Interventions

• OTHER

No Results Yet

NCT04743401 | COMPLETED | NA

54 participants

Feasibility of a Tele-game-based Exercise (Tele-exergame) Program to Prevent Deconditioning in Hospitalized COVID-19 Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-07-05

Completion:

2023-12-31

Conditions

• COVID 19
• Rehabilitation
• Inpatient
• Hospitalized

Interventions

• OTHER

Results Available

NCT04739189 | COMPLETED | NA

20 participants

Appetite Response to Exercise- Versus Energy Restriction-induced Energy Deficit in Adolescents With Obesity.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-08-28

Completion:

2021-10-03

Conditions

• Pediatric Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT04730479 | COMPLETED

330 participants

Echography to Predict Radial Artery Catheterization Failure (EPRAC)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2021-04-15

Completion:

2022-04-06

Conditions

• Cardiac and Aortic Surgery

No Results Yet

NCT04729933 | ACTIVE_NOT_RECRUITING | NA

16 participants

Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-03-11

Completion:

2025-01-03

Conditions

• Heart Failure
• Mitral Regurgitation

Interventions

• DEVICE

Results Available

NCT04713982 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

30 participants

Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2021-11-19

Completion:

2027-06-30

Conditions

• Huntington Disease

Interventions

• DRUG

No Results Yet

NCT04651504 | COMPLETED | NA

185903 participants

Rural Colon Cancer Screening Toolkit Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-12-02

Completion:

2024-12-31

Conditions

• Colon Cancer Screening

Interventions

• OTHER

Results Available

NCT04649086 | TERMINATED | NA

60 participants

Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2020-06-05

Completion:

2022-01-07

Conditions

• Covid19
• Sarcopenia
• Muscle Weakness

Interventions

• OTHER

No Results Yet