Clinical Trials

NCT05422573 | COMPLETED | NA

393 participants

Clinical Trial of the Sequence of Cardiovascular Genetic Counseling and Testing

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-12-20

Completion:

2026-05-21

Conditions

• Genetic Counseling
• Inherited Cardiac Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT05411081 | ACTIVE_NOT_RECRUITING | PHASE2

200 participants

Testing Cabozantinib With or Without Atezolizumab in Patients With Advanced Papillary Kidney Cancer, PAPMET2 Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-03-24

Completion:

2027-07-01

Conditions

• Metastatic Papillary Renal Cell Carcinoma
• Stage IV Renal Cell Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT05398783 | RECRUITING

2000 participants

A Natural History Study of Metabolic Sizing in Health and Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2022-10-25

Completion:

2031-07-01

Conditions

• Metabolic Disorders
• Cancer
• Chronic Kidney Disease
• Diabetes
• Normal Physiology

No Results Yet

NCT05397431 | ACTIVE_NOT_RECRUITING

155 participants

A Survey of Lanadelumab in Participants With Hereditary Angioedema

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2022-05-30

Completion:

2026-10-27

Conditions

• Hereditary Angioedema (HAE)

Interventions

• DRUG

No Results Yet

NCT05384847 | COMPLETED | PHASE1

14 participants

Effects of Triiodothyronine (T3) in Ischemic Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-12-02

Completion:

2025-10-01

Conditions

• Heart Failure

Interventions

• DRUG
• OTHER

No Results Yet

NCT05375682 | COMPLETED | NA

30 participants

Integrating Care for Patients With Alcohol Liver Disease and Alcohol Use Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2024-04-01

Completion:

2026-04-15

Conditions

• Alcohol; Liver

Interventions

• OTHER

No Results Yet

NCT05363813 | COMPLETED | NA

245 participants

Post-market Clinical Follow-up Study of Reusable Clip Applier Cartridge Devices for LAParoscopic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-10-17

Completion:

2024-08-19

Conditions

• Minimally Invasive Surgical Procedures
• Laparoscopy
• Leakage of Cardiac Device

Interventions

• DEVICE

Results Available

NCT05348005 | COMPLETED | NA

40 participants

Use of TENS Unit in the Management of Endometriosis Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-07-28

Completion:

2025-07-16

Conditions

• Endometriosis
• Pelvic Pain

Interventions

• DEVICE

Results Available

NCT05341115 | COMPLETED | PHASE4

79 participants

A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-03-12

Completion:

2024-12-19

Conditions

• Central Precocious Puberty

Interventions

• DRUG

Results Available

NCT05312879 | RECRUITING | PHASE2/PHASE3

466 participants

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-03-30

Completion:

2028-06-02

Conditions

• Proteinuric Kidney Disease

Interventions

• DRUG

No Results Yet

NCT05272423 | COMPLETED

58 participants

Studying Pathways of Resistance in KRAS-driven Cancers

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2022-09-08

Completion:

2025-12-10

Conditions

• KRAS P.G12C

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05258357 | COMPLETED | NA

100 participants

Landmark vs. Ultrasound-Assisted Bone Marrow Biopsy Procedure Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-05-18

Completion:

2026-05-12

Conditions

• Bone Marrow Biopsy Procedure

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT05250050 | WITHDRAWN | PHASE4

0 participants

Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-03-25

Completion:

2022-12-30

Conditions

• Helicobacter Pylori Infection

Interventions

• DRUG

No Results Yet

NCT05246579 | RECRUITING

240 participants

Prospective Evaluation of Pathways for Preterm Birth

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2022-02-04

Completion:

2027-07-01

Conditions

• Preterm Birth
• Cervix; Pregnancy

No Results Yet

NCT05238792 | RECRUITING | PHASE1

24 participants

Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2021-11-17

Completion:

2028-10-31

Conditions

• Solid Tumor

Interventions

• BIOLOGICAL

No Results Yet

NCT05224557 | WITHDRAWN

0 participants

Analysis of Cardiac Biomarker Racial Discrepancies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2021-09-15

Completion:

2027-08-15

Conditions

• Heart Failure

Interventions

• OTHER

No Results Yet

NCT05202353 | ACTIVE_NOT_RECRUITING | PHASE1

29 participants

A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2024-10-01

Completion:

2026-12-18

Conditions

• Obesity

Interventions

• DRUG

No Results Yet

NCT05199285 | TERMINATED | PHASE2

15 participants

A Phase II Study of Nivolumab + Ipilimumab in Advanced HCC Patients Who Have Progressed on First Line Atezolizumab + Bevacizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-01-19

Completion:

2026-02-01

Conditions

• BCLC Stage B Hepatocellular Carcinoma
• BCLC Stage C Hepatocellular Carcinoma
• Locally Advanced Hepatocellular Carcinoma
• Metastatic Hepatocellular Carcinoma
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage IIIA Hepatocellular Carcinoma AJCC v8
• Stage IIIB Hepatocellular Carcinoma AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8
• Unresectable Hepatocellular Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT05174169 | RECRUITING | PHASE2/PHASE3

1912 participants

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-07-08

Completion:

2029-03-10

Conditions

• Stage III Colon Cancer

Interventions

• DEVICE
• DRUG

No Results Yet

NCT05170399 | RECRUITING | PHASE4

350 participants

Vaccine Responses in Patients With B Cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-09-14

Completion:

2036-11-15

Conditions

• Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05168163 | RECRUITING | PHASE2

122 participants

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-05-27

Completion:

2026-06-30

Conditions

• Locally Advanced Hepatocellular Carcinoma
• Metastatic Hepatocellular Carcinoma
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage IIIA Hepatocellular Carcinoma AJCC v8
• Stage IIIB Hepatocellular Carcinoma AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8
• Unresectable Hepatocellular Carcinoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05132504 | RECRUITING | PHASE2

30 participants

Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-08-31

Completion:

2027-05-21

Conditions

• Pancreatic Ductal Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT05111574 | ACTIVE_NOT_RECRUITING | PHASE2

101 participants

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-08-11

Completion:

2027-07-15

Conditions

• Anal Melanoma
• Bladder Melanoma
• Cervical Melanoma
• Esophageal Melanoma
• Gallbladder Melanoma
• Head and Neck Mucosal Melanoma
• Mucosal Melanoma
• Nasopharyngeal Mucosal Melanoma
• Oral Cavity Mucosal Melanoma
• Penile Mucosal Melanoma
• Rectal Melanoma
• Recurrent Mucosal Melanoma
• Sinonasal Mucosal Melanoma
• Urethral Melanoma
• Urinary System Mucosal Melanoma
• Vaginal Melanoma
• Vulvar Melanoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT05080673 | RECRUITING | NA

9500 participants

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-02-09

Completion:

2035-11-01

Conditions

• Adenocarcinoma of the Colon
• Adenocarcinoma of the Rectum

Interventions

• PROCEDURE

No Results Yet

NCT05080166 | COMPLETED | NA

74 participants

UPLYFT For Lymphoma Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-02-08

Completion:

2026-07-17

Conditions

• Lymphoma
• Survivorship

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT05068102 | ACTIVE_NOT_RECRUITING | PHASE1

14 participants

A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-03-03

Completion:

2026-01-22

Conditions

• Carcinoma, Squamous Cell of Head and Neck (HNSCC)
• Melanoma
• Non-small Cell Lung Cancer (NSCLC)

Interventions

• DRUG

No Results Yet

NCT05050916 | COMPLETED | PHASE2

998 participants

The Investigation of Vitamin D and Menstrual Cycles Trial, the inVitD Trial: A Phase II Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-03-17

Completion:

2024-06-07

Conditions

• Reproductive Issues

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT05016700 | COMPLETED

100 participants

Neuropathological Changes of the Intestinal Wall in Patients With Bowel Evacuation Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2019-03-20

Completion:

2025-04-01

Conditions

• Defecation Disorder
• Neuropathology
• Autoimmune Diseases

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05006833 | COMPLETED | NA

8043 participants

Text and Talk: A Multi-level Intervention to Increase Provider HPV Vaccine Recommendation Effectiveness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2021-11-18

Completion:

2025-02-25

Conditions

• HPV

Interventions

• BEHAVIORAL

Results Available

NCT05004662 | COMPLETED | NA

502 participants

Partnering With Food Bank to Provide Tobacco Treatment to Underserved Smokers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2021-12-01

Completion:

2025-06-05

Conditions

• Smoking Cessation

Interventions

• BEHAVIORAL
• DRUG

Results Available

NCT04969926 | RECRUITING

3000 participants

Natural History Study of Parathyroid Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2021-11-30

Completion:

2031-01-22

Conditions

• Parathyroid Cancer
• Primary Hyperparathyroidism
• Pseudohypoparathyroidism
• Inheritable Bone Diseases
• Multiple Endocrine Neoplasia, Type 1

No Results Yet

NCT04958239 | ACTIVE_NOT_RECRUITING | PHASE1

151 participants

A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2021-10-18

Completion:

2026-04-27

Conditions

• Neoplasms

Interventions

• DRUG

No Results Yet

NCT04949100 | ACTIVE_NOT_RECRUITING | NA

50 participants

Microcurrent for Fibromyalgia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2021-10-25

Completion:

2026-12-31

Conditions

• Fibromyalgia

Interventions

• DEVICE

No Results Yet

NCT04943861 | RECRUITING | NA

200 participants

Human Immunodeficiency Virus (HIV) Food Insecurities

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-12-01

Completion:

2027-02-28

Conditions

• Food Insecurities
• Cardiometabolic Comorbidities
• HIV
• PreDiabetes
• Type 2 Diabetes Mellitus (T2DM)

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04920097 | COMPLETED | NA

238 participants

Auricular Point Acupressure to Manage Chemotherapy Induced Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2021-07-08

Completion:

2025-05-30

Conditions

• Chemotherapy-induced Neuropathy

Interventions

• OTHER

Results Available

NCT04910685 | RECRUITING | PHASE2/PHASE3

534 participants

(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2021-11-30

Completion:

2032-09-30

Conditions

• Indolent Systemic Mastocytosis
• Smoldering Systemic Mastocytosis

Interventions

• DRUG

No Results Yet

NCT04905914 | COMPLETED | PHASE1/PHASE2

43 participants

Study Of ATRN-119 In Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-01-09

Completion:

2026-03-09

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT04902053 | SUSPENDED

50 participants

INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2028-06-30

Completion:

2030-12-31

Conditions

• Aortic Valve Replacement

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04887870 | COMPLETED | PHASE2/PHASE3

49 participants

Study of Sitravatinib With or Without Other Anticancer Therapies Receiving Clinical Benefit From Parent Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2021-06-29

Completion:

2025-04-21

Conditions

• Advanced or Metastatic Solid Malignancies

Interventions

• DRUG

Results Available

NCT04864886 | RECRUITING

300 participants

Metabolic Profiling of Immune Responses in Immune-mediated Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2021-08-10

Completion:

2027-06-30

Conditions

• Primary Immunodeficiency
• Psoriasis
• Atopic Dermatitis
• Immune-mediated Diseases

No Results Yet