Clinical Trials

NCT05910021 | COMPLETED

35 participants

Early Safety of Resection Rectopexy and Sacrocolpopexy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2020-02-01

Completion:

2024-03-31

Conditions

• Constipation by Outlet Obstruction
• Pelvic Organ Prolapse
• Urinary Incontinence

No Results Yet

NCT05906537 | COMPLETED | PHASE1

38 participants

SKB410 for Injection in Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-07-06

Completion:

2026-03-31

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT05890183 | RECRUITING | NA

100 participants

Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-05-23

Completion:

2028-05-31

Conditions

• Schizophrenia
• Schizophreniform Disorder
• Schizoaffective Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05887713 | ACTIVE_NOT_RECRUITING | NA

200 participants

Novel Mental Health Therapies to Improve Military Readiness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2024-01-01

Completion:

2026-12-31

Conditions

• Anxiety
• Alpha Stim
• Cranial Electrotherapy Stimulation
• Cognitive Behavioral Therapy
• Heart Rate Variability

Interventions

• DEVICE

No Results Yet

NCT05879978 | ACTIVE_NOT_RECRUITING | PHASE1

45 participants

A Study to Test How Well Different Doses of Obrixtamig (BI 764532) in Combination With Ezabenlimab Are Tolerated by People With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-06-27

Completion:

2025-06-11

Conditions

• Small Cell Lung Carcinoma (SCLC)
• Neuroendocrine Neoplasms

Interventions

• DRUG

No Results Yet

NCT05875740 | RECRUITING

80 participants

Correlation of Memory CD8+ T Cells With Sepsis Severity and Mortality: a Single-center, Unblinded, Prospective, Non-interventional, Observational Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2023-09-06

Completion:

2026-08-31

Conditions

• Sepsis
• Inflammatory Response

No Results Yet

NCT05874843 | RECRUITING | NA

125 participants

Validation of Point-of-care Thromboelastography (TEG 6s) in Pediatric Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-09-11

Completion:

2026-12-31

Conditions

• Coagulopathy

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05816889 | COMPLETED

56 participants

Investigation of Exercise Capacity, Muscle Oxygenation and Physical Activity Level in Parkinson's Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2023-04-01

Completion:

2024-05-20

Conditions

• Parkinson Disease

No Results Yet

NCT05663515 | RECRUITING

24000 participants

A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2024-09-30

Completion:

2026-10-01

Conditions

• Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT05621564 | RECRUITING

6032 participants

Pre-operative Therapy in Breast Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2022-11-01

Completion:

2030-11-30

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05619991 | COMPLETED | NA

90 participants

Effect of Short Film Video and Video-Based Education on Fear, Pain, and Satisfaction of Children Undergoing Day Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-12-01

Completion:

2023-10-25

Conditions

• Day Surgery
• Fear
• Pain
• Satisfaction
• CHİLDREN

Interventions

• OTHER

No Results Yet

NCT05619627 | NOT_YET_RECRUITING | PHASE1

18 participants

Oral Dexmedetomidine in Pediatric MRI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2026-11-01

Completion:

2027-11-30

Conditions

• Anesthesia

Interventions

• DRUG

No Results Yet

NCT05618379 | ACTIVE_NOT_RECRUITING

200 participants

Adult Spinal Muscular Atrophy (SMA) China Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2023-01-06

Completion:

2028-06-01

Conditions

• Muscular Atrophy, Spinal

No Results Yet

NCT05609916 | RECRUITING | NA

200 participants

CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-11-30

Completion:

2027-07-30

Conditions

• Cognitive Behavioral Therapy
• Obsessive-Compulsive Disorder
• Obsessive-Compulsive Disorder in Children
• Obsessive-Compulsive Disorder in Adolescence

Interventions

• BEHAVIORAL

No Results Yet

NCT05586243 | RECRUITING

5 participants

MAGNETIC RESONANCE SPECTROSCOPY BIOMARKERS IN TYPE 3 GAUCHER DISEASE (GD3)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2023-01-01

Completion:

2026-12-31

Conditions

• Gaucher Disease, Type 3

Interventions

• OTHER

No Results Yet

NCT05579366 | RECRUITING | PHASE1/PHASE2

884 participants

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-12-07

Completion:

2027-07-31

Conditions

• High Grade Epithelial Ovarian Cancer
• High Grade Serous Ovarian Cancer
• Primary Peritoneal Carcinoma
• Fallopian Tube Cancer
• Endometrial Cancer
• Non-small Cell Lung Cancer
• Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC)
• Mesothelioma
• Breast Adenocarcinoma
• Triple Negative Breast Cancer
• Hormone Receptor-positive/Her2 Negative Breast Cancer
• Platinum-resistant Ovarian Cancer (PROC)
• Platinum Sensitive Ovarian Cancer (PSOC)
• Primary Refractory Ovarian Cancer
• Uterine Cancer

Interventions

• DRUG

No Results Yet

NCT05567198 | RECRUITING

100 participants

Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2023-03-03

Completion:

2027-05-31

Conditions

• Systemic Lupus Erythematosus (Sle)
• Primary Ovarian Insufficiency (Poi)

No Results Yet

NCT05564403 | ACTIVE_NOT_RECRUITING | PHASE2

66 participants

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2024-02-09

Completion:

2026-10-01

Conditions

• Advanced Biliary Tract Carcinoma
• Advanced Gallbladder Carcinoma
• Advanced Intrahepatic Cholangiocarcinoma
• Recurrent Biliary Tract Carcinoma
• Recurrent Gallbladder Carcinoma
• Recurrent Intrahepatic Cholangiocarcinoma
• Stage III Distal Bile Duct Cancer AJCC v8
• Stage III Gallbladder Cancer AJCC v8
• Stage III Hilar Cholangiocarcinoma AJCC v8
• Stage III Intrahepatic Cholangiocarcinoma AJCC v8
• Stage IV Distal Bile Duct Cancer AJCC v8
• Stage IV Gallbladder Cancer AJCC v8
• Stage IV Hilar Cholangiocarcinoma AJCC v8
• Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
• Unresectable Biliary Tract Carcinoma
• Unresectable Gallbladder Carcinoma
• Unresectable Intrahepatic Cholangiocarcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05554341 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-07-14

Completion:

2027-06-30

Conditions

• Metastatic Malignant Solid Neoplasm
• Refractory Malignant Solid Neoplasm

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05554328 | ACTIVE_NOT_RECRUITING | PHASE2

165 participants

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-04-25

Completion:

2028-10-01

Conditions

• Recurrent Endometrial Carcinoma
• Recurrent Fallopian Tube Carcinoma
• Recurrent Ovarian Carcinoma
• Recurrent Primary Peritoneal Carcinoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05471856 | RECRUITING | PHASE1

66 participants

A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-02-24

Completion:

2028-09-13

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT05397431 | ACTIVE_NOT_RECRUITING

155 participants

A Survey of Lanadelumab in Participants With Hereditary Angioedema

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2022-05-30

Completion:

2026-10-27

Conditions

• Hereditary Angioedema (HAE)

Interventions

• DRUG

No Results Yet

NCT05384847 | COMPLETED | PHASE1

14 participants

Effects of Triiodothyronine (T3) in Ischemic Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-12-02

Completion:

2025-10-01

Conditions

• Heart Failure

Interventions

• DRUG
• OTHER

No Results Yet

NCT05375682 | COMPLETED | NA

30 participants

Integrating Care for Patients With Alcohol Liver Disease and Alcohol Use Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2024-04-01

Completion:

2026-04-15

Conditions

• Alcohol; Liver

Interventions

• OTHER

No Results Yet

NCT05363813 | COMPLETED | NA

245 participants

Post-market Clinical Follow-up Study of Reusable Clip Applier Cartridge Devices for LAParoscopic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-10-17

Completion:

2024-08-19

Conditions

• Minimally Invasive Surgical Procedures
• Laparoscopy
• Leakage of Cardiac Device

Interventions

• DEVICE

Results Available

NCT05348005 | COMPLETED | NA

40 participants

Use of TENS Unit in the Management of Endometriosis Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-07-28

Completion:

2025-07-16

Conditions

• Endometriosis
• Pelvic Pain

Interventions

• DEVICE

Results Available

NCT05341115 | COMPLETED | PHASE4

79 participants

A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-03-12

Completion:

2024-12-19

Conditions

• Central Precocious Puberty

Interventions

• DRUG

Results Available

NCT05272423 | COMPLETED

58 participants

Studying Pathways of Resistance in KRAS-driven Cancers

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2022-09-08

Completion:

2025-12-10

Conditions

• KRAS P.G12C

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05258357 | COMPLETED | NA

100 participants

Landmark vs. Ultrasound-Assisted Bone Marrow Biopsy Procedure Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-05-18

Completion:

2026-05-12

Conditions

• Bone Marrow Biopsy Procedure

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT05250050 | WITHDRAWN | PHASE4

0 participants

Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-03-25

Completion:

2022-12-30

Conditions

• Helicobacter Pylori Infection

Interventions

• DRUG

No Results Yet

NCT05246579 | RECRUITING

240 participants

Prospective Evaluation of Pathways for Preterm Birth

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2022-02-04

Completion:

2027-07-01

Conditions

• Preterm Birth
• Cervix; Pregnancy

No Results Yet

NCT05238792 | RECRUITING | PHASE1

24 participants

Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2021-11-17

Completion:

2028-10-31

Conditions

• Solid Tumor

Interventions

• BIOLOGICAL

No Results Yet

NCT05224557 | WITHDRAWN

0 participants

Analysis of Cardiac Biomarker Racial Discrepancies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2021-09-15

Completion:

2027-08-15

Conditions

• Heart Failure

Interventions

• OTHER

No Results Yet

NCT05199285 | TERMINATED | PHASE2

15 participants

A Phase II Study of Nivolumab + Ipilimumab in Advanced HCC Patients Who Have Progressed on First Line Atezolizumab + Bevacizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2023-01-19

Completion:

2026-02-01

Conditions

• BCLC Stage B Hepatocellular Carcinoma
• BCLC Stage C Hepatocellular Carcinoma
• Locally Advanced Hepatocellular Carcinoma
• Metastatic Hepatocellular Carcinoma
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage IIIA Hepatocellular Carcinoma AJCC v8
• Stage IIIB Hepatocellular Carcinoma AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8
• Unresectable Hepatocellular Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT05170399 | RECRUITING | PHASE4

350 participants

Vaccine Responses in Patients With B Cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-09-14

Completion:

2036-11-15

Conditions

• Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05168163 | RECRUITING | PHASE2

122 participants

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-05-27

Completion:

2026-06-30

Conditions

• Locally Advanced Hepatocellular Carcinoma
• Metastatic Hepatocellular Carcinoma
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage IIIA Hepatocellular Carcinoma AJCC v8
• Stage IIIB Hepatocellular Carcinoma AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8
• Unresectable Hepatocellular Carcinoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05132504 | RECRUITING | PHASE2

30 participants

Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-08-31

Completion:

2027-05-21

Conditions

• Pancreatic Ductal Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT05111574 | ACTIVE_NOT_RECRUITING | PHASE2

101 participants

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-08-11

Completion:

2027-07-15

Conditions

• Anal Melanoma
• Bladder Melanoma
• Cervical Melanoma
• Esophageal Melanoma
• Gallbladder Melanoma
• Head and Neck Mucosal Melanoma
• Mucosal Melanoma
• Nasopharyngeal Mucosal Melanoma
• Oral Cavity Mucosal Melanoma
• Penile Mucosal Melanoma
• Rectal Melanoma
• Recurrent Mucosal Melanoma
• Sinonasal Mucosal Melanoma
• Urethral Melanoma
• Urinary System Mucosal Melanoma
• Vaginal Melanoma
• Vulvar Melanoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT05080166 | COMPLETED | NA

74 participants

UPLYFT For Lymphoma Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-02-08

Completion:

2026-07-17

Conditions

• Lymphoma
• Survivorship

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT05068102 | ACTIVE_NOT_RECRUITING | PHASE1

14 participants

A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2022-03-03

Completion:

2026-01-22

Conditions

• Carcinoma, Squamous Cell of Head and Neck (HNSCC)
• Melanoma
• Non-small Cell Lung Cancer (NSCLC)

Interventions

• DRUG

No Results Yet