Clinical Trials

NCT03643549 | RECRUITING | PHASE1/PHASE2

63 participants

Bortezomib and Temozolomide in Recurrent Grade-4 Glioma Unmethylated MGMT Promoter (BORTEM-17)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2018-08-30

Completion:

2026-12-30

Conditions

• Glioblastoma

Interventions

• DRUG

No Results Yet

NCT03531099 | ACTIVE_NOT_RECRUITING | PHASE3

108 participants

Phase 3, Multicenter, Randomized Study, Evaluating the Efficacy and Tolerability of Focused HIFU (High Intensity Focused Ultrasound) Therapy Compared to Active Surveillance in Patients With Significant Low Risk Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2018-10-02

Completion:

2026-10-02

Conditions

• Prostate Cancer

Interventions

• PROCEDURE
• BIOLOGICAL
• DEVICE
• OTHER

No Results Yet

NCT03521154 | ACTIVE_NOT_RECRUITING | PHASE3

216 participants

A Global Study to Assess the Effects of Osimertinib Following Chemoradiation in Patients With Stage III Unresectable Non-small Cell Lung Cancer (LAURA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2018-07-19

Completion:

2024-01-05

Conditions

• Non Small Cell Lung Cancer (Stage III)

Interventions

• DRUG

Results Available

NCT03474718 | NOT_YET_RECRUITING | EARLY_PHASE1

16 participants

Evaluating the Efficacy of Platelet-rich Plasma Therapy in the Treatment of Androgenic Alopecia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2026-10-31

Completion:

2027-07-31

Conditions

• Androgenic Alopecia

Interventions

• BIOLOGICAL

No Results Yet

NCT03455582 | COMPLETED | NA

66 participants

Cognition Evolution and MRI Markers in PPMS Patients on 2 Years

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2018-09-24

Completion:

2026-04-15

Conditions

• Multiple Sclerosis, Primary Progressive

Interventions

• OTHER
• DEVICE

No Results Yet

NCT03427970 | COMPLETED | NA

42 participants

Efficacy of Three-dimensionally Integrated Exercise for Scoliosis in Patients With Adolescent Idiopathic Scoliosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2018-06-25

Completion:

2021-12-31

Conditions

• Scoliosis,Idiopathic,Adolescent

Interventions

• BEHAVIORAL

No Results Yet

NCT03375320 | ACTIVE_NOT_RECRUITING | PHASE3

298 participants

Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2018-10-26

Completion:

2023-08-23

Conditions

• Functioning Pancreatic Neuroendocrine Tumor
• Intermediate Grade Lung Neuroendocrine Neoplasm
• Locally Advanced Digestive System Neuroendocrine Neoplasm
• Locally Advanced Digestive System Neuroendocrine Tumor G1
• Locally Advanced Lung Neuroendocrine Neoplasm
• Locally Advanced Pancreatic Neuroendocrine Tumor
• Locally Advanced Unresectable Digestive System Neuroendocrine Neoplasm
• Low Grade Lung Neuroendocrine Neoplasm
• Lung Neuroendocrine Tumor
• Lung Neuroendocrine Tumor G2
• Metastatic Digestive System Neuroendocrine Neoplasm
• Metastatic Digestive System Neuroendocrine Tumor G1
• Metastatic Lung Neuroendocrine Neoplasm
• Metastatic Lung Neuroendocrine Tumor
• Metastatic Pancreatic Neuroendocrine Neoplasm
• Metastatic Pancreatic Neuroendocrine Tumor
• Metastatic Thymus Neuroendocrine Neoplasm
• Neuroendocrine Neoplasm
• Neuroendocrine Tumor
• Neuroendocrine Tumor G2
• Non-Functioning Pancreatic Neuroendocrine Tumor
• Pancreatic Serotonin-Producing Neuroendocrine Tumor
• Thymus Neuroendocrine Tumor
• Unresectable Digestive System Neuroendocrine Neoplasm
• Unresectable Digestive System Neuroendocrine Tumor G1
• Unresectable Lung Neuroendocrine Neoplasm
• Unresectable Pancreatic Neuroendocrine Neoplasm
• Unresectable Thymus Neuroendocrine Neoplasm

Interventions

• PROCEDURE
• DRUG
• OTHER

Results Available

NCT03368664 | TERMINATED | PHASE3

16 participants

A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2017-10-23

Completion:

2021-05-04

Conditions

• Multiple Sclerosis

Interventions

• DRUG

Results Available

NCT03351348 | ACTIVE_NOT_RECRUITING | PHASE3

165 participants

Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2017-11-16

Completion:

2027-11-30

Conditions

• Breast Cancer

Interventions

• DRUG
• BEHAVIORAL
• OTHER

No Results Yet

NCT03228537 | ACTIVE_NOT_RECRUITING | PHASE1

28 participants

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2018-07-16

Completion:

2022-10-01

Conditions

• Biphasic Mesothelioma
• Epithelioid Mesothelioma
• Stage I Pleural Diffuse Malignant Mesothelioma AJCC v7
• Stage IA Pleural Diffuse Malignant Mesothelioma AJCC v7
• Stage IB Pleural Diffuse Malignant Mesothelioma AJCC v7
• Stage II Pleural Diffuse Malignant Mesothelioma AJCC v7
• Stage III Pleural Diffuse Malignant Mesothelioma AJCC v7

Interventions

• DRUG
• PROCEDURE
• RADIATION

Results Available

NCT03191149 | RECRUITING | PHASE2

46 participants

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2018-04-25

Completion:

2027-06-30

Conditions

• Advanced Lung Non-Small Cell Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Stage IIIB Lung Non-Small Cell Cancer AJCC v7
• Stage IV Lung Non-Small Cell Cancer AJCC v7

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT03143270 | COMPLETED | EARLY_PHASE1

20 participants

A Study to Test the Safety and Feasibility of Nivolumab With Drug Eluting Bead Transarterial Chemoembolization in Patients With Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2017-04-28

Completion:

2026-08-03

Conditions

• Liver Cancer

Interventions

• DRUG

No Results Yet

NCT03085147 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

23 participants

A Dye for the Detection of Cancer of the Tongue and Mouth

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2017-03-15

Completion:

2027-07-31

Conditions

• Oral Squamous Cell Carcinoma (OSCC)

Interventions

• DRUG

No Results Yet

NCT03071536 | COMPLETED | NA

360 participants

Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2016-11-25

Completion:

2026-08-03

Conditions

• Kidney Function
• Kidney Transplant; Complications
• Delayed Graft Function

Interventions

• DRUG

No Results Yet

NCT03029884 | COMPLETED | NA

4 participants

Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2017-10-28

Completion:

2023-09-30

Conditions

• Chronic Pain
• Post Stroke Pain
• Phantom Limb Pain
• Spinal Cord Injuries

Interventions

• DEVICE

Results Available

NCT02968043 | COMPLETED | NA

42 participants

Efficacy of Physiotherapeutic Scoliosis Specific Exercises in Adolescent Idiopathic Scoliosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2017-02-01

Completion:

2021-12-31

Conditions

• Scoliosis Idiopathic Adolescent

Interventions

• OTHER

No Results Yet

NCT02912559 | ACTIVE_NOT_RECRUITING | PHASE3

712 participants

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2017-10-16

Completion:

2025-02-04

Conditions

• Colon Adenocarcinoma
• DNA Repair Disorder
• Lynch Syndrome
• Stage III Colon Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• OTHER

Results Available

NCT02698293 | WITHDRAWN | PHASE1

0 participants

PDT Plus Vitamin D3 for Anal Dysplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2019-12-01

Completion:

2022-08-03

Conditions

• Anal Dysplasia
• Carcinoma in Situ

Interventions

• DRUG
• OTHER

No Results Yet

NCT02573753 | RECRUITING | NA

5000 participants

The Effects of Sleep on Human Microbiota: Implications for Health and Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2015-10-31

Completion:

2031-12-31

Conditions

• Sleep

Interventions

• BEHAVIORAL
• DIETARY_SUPPLEMENT

No Results Yet

NCT02507141 | RECRUITING

140 participants

Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2015-07-21

Completion:

2027-07-31

Conditions

• Head and Neck Cancer
• Squamous Cell Carcinoma (SCC) of the Oral Cavity

Interventions

• DEVICE

No Results Yet

NCT02498912 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2015-08-31

Completion:

2026-08-31

Conditions

• Solid Tumors

Interventions

• PROCEDURE
• DRUG
• DEVICE
• GENETIC

No Results Yet

NCT02213926 | ACTIVE_NOT_RECRUITING | PHASE2

124 participants

An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2015-03-02

Completion:

2020-12-04

Conditions

• Mantle Cell Lymphoma (MCL)

Interventions

• DRUG

Results Available

NCT02211768 | COMPLETED | PHASE1

10 participants

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-12-08

Completion:

2017-09-05

Conditions

• Neurofibromatosis
• MPNST

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT02143414 | ACTIVE_NOT_RECRUITING | PHASE2

53 participants

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2015-06-30

Completion:

2022-06-01

Conditions

• Acute Lymphoblastic Leukemia
• B Acute Lymphoblastic Leukemia
• B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
• Recurrent Acute Lymphoblastic Leukemia
• Refractory Acute Lymphoblastic Leukemia

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

Results Available

NCT02115282 | ACTIVE_NOT_RECRUITING | PHASE3

608 participants

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-03-29

Completion:

2020-05-05

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Breast Adenocarcinoma
• HER2/Neu Negative
• Locally Advanced Breast Carcinoma
• Metastatic Breast Carcinoma
• Recurrent Breast Carcinoma

Interventions

• PROCEDURE
• DRUG
• OTHER

Results Available

NCT02101788 | COMPLETED | PHASE2/PHASE3

260 participants

Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-04-11

Completion:

2019-04-04

Conditions

• Borderline Ovarian Serous Tumor
• Micropapillary Serous Carcinoma
• Ovarian Serous Adenocarcinoma
• Primary Peritoneal Serous Adenocarcinoma
• Recurrent Ovarian Low Grade Serous Adenocarcinoma
• Recurrent Primary Peritoneal Serous Adenocarcinoma

Interventions

• DRUG
• OTHER

Results Available

NCT02075463 | TERMINATED | PHASE2

15 participants

Study to Evaluate the Safety and Efficacy of GSK1278863 in Recombinant Human Erythropoietin (rhEPO) Hyporesponsive Hemodialysis-dependent Chronic Kidney Disease Subjects With Anemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-06-11

Completion:

2016-03-16

Conditions

• Anemia
• Anaemia

Interventions

• DRUG

Results Available

NCT02003222 | ACTIVE_NOT_RECRUITING | PHASE3

488 participants

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-05-19

Completion:

2023-06-23

Conditions

• Acute Lymphoblastic Leukemia
• B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

Results Available

NCT01845883 | WITHDRAWN | NA

0 participants

Perceptual Decision Making Under Conditions of Visual Uncertainty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2013-04-30

Completion:

2015-12-31

Conditions

• Parkinson's Disease
• Dystonia
• Ataxia

Interventions

• PROCEDURE

No Results Yet

NCT01639508 | RECRUITING | PHASE2

86 participants

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2012-07-31

Completion:

2027-07-31

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT01439659 | ACTIVE_NOT_RECRUITING | PHASE2

75 participants

Juice Plus+ and Juice Plus+ Complete in Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2003-02-18

Completion:

2028-03-01

Conditions

• Ovarian Cancer

Interventions

• BEHAVIORAL
• DIETARY_SUPPLEMENT

No Results Yet

NCT01386385 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

53 participants

Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2011-06-20

Completion:

2019-05-26

Conditions

• Lung Adenocarcinoma
• Lung Adenocarcinoma, Mixed Subtype
• Lung Large Cell Carcinoma
• Lung Squamous Cell Carcinoma
• Minimally Invasive Lung Adenocarcinoma
• Stage III Lung Non-Small Cell Cancer AJCC v7
• Stage IIIA Lung Non-Small Cell Cancer AJCC v7
• Stage IIIB Lung Non-Small Cell Cancer AJCC v7

Interventions

• RADIATION
• DRUG
• OTHER

Results Available

NCT01352975 | COMPLETED

217 participants

Study of Dark Adaptation in Age-Related Macular Degeneration

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2011-05-16

Conditions

• Age-Related Macular Degeneration

No Results Yet

NCT01169337 | ACTIVE_NOT_RECRUITING | PHASE3

226 participants

Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2011-01-24

Completion:

2019-01-25

Conditions

• Light Chain Deposition Disease
• Smoldering Multiple Myeloma

Interventions

• OTHER
• DRUG

Results Available

NCT00600665 | COMPLETED | NA

279 participants

Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2007-02-28

Completion:

2013-06-30

Conditions

• Anemia, Sickle Cell
• Hemoglobin SC Disease

Interventions

• BEHAVIORAL

Results Available

NCT00365859 | COMPLETED | PHASE3

330 participants

Study of Aripiprazole in the Treatment of Serious Behavioral Problems in Children and Adolescents With Autistic Disorder (AD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2006-09-01

Completion:

2009-06-01

Conditions

• Autistic Disorder
• Behavioral Symptoms

Interventions

• DRUG

Results Available

NCT00098072 | COMPLETED | PHASE1

27 participants

Endothelial Cell Dysfunction in Pulmonary Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2000-05-17

Completion:

2009-07-08

Conditions

• Secondary Pulmonary Arterial Hypertension

Interventions

• PROCEDURE

No Results Yet

NCT00023036 | COMPLETED

324 participants

Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2001-09-04

Conditions

• Sensorineural Hearing Loss
• Cytomegalovirus Infection

No Results Yet

NCT07743411 | NOT_YET_RECRUITING

180 participants

A Clinical Trial of the ACYW135 Group Meningococcal Polysaccharide-Conjugated Vaccine (CRM197 Vector)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-03

Start Date:

2026-09-15

Completion:

2028-09-15

Conditions

• Epidemic Meningitis

Interventions

• OTHER

No Results Yet

NCT07743372 | NOT_YET_RECRUITING | NA

90 participants

Effect of Preoperative Diclofenac Potassium Dose on Endodontic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2026-08-31

Completion:

2027-08-31

Conditions

• Symptomatic Irreversible Pulpitis (SIP)

Interventions

• DRUG

No Results Yet