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Effect of Preoperative Diclofenac Potassium Dose on Endodontic Pain

NCT07743372 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2026-08-03

No results posted yet for this study

Summary

The aim of this study is to assess the effect of different doses of diclofenac potassium premedication (100mg vs 50mg) on anesthetic success of 4% articaine buccal infiltration and post-operative pain as compared to placebo in mandibular molars with symptomatic irreversible pulpitis.

Conditions

  • Symptomatic Irreversible Pulpitis (SIP)

Interventions

DRUG

Diclofenac potassium 100mg

Preoperative single dose of diclofenac potassium 100mg

DRUG

Diclofenac potassium 50mg

Preoperative single dose of diclofenac potassium 50mg

DRUG

Placebo

Preoperative placebo

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-31
Primary Completion
2027-08-31
Completion
2028-02-29

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Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07743372 on ClinicalTrials.gov