Clinical Trials

NCT03143270 | COMPLETED | EARLY_PHASE1

20 participants

A Study to Test the Safety and Feasibility of Nivolumab With Drug Eluting Bead Transarterial Chemoembolization in Patients With Liver Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2017-04-28
Completion:: 2026-08-03

Conditions

Liver Cancer

Interventions

DRUG

No Results Yet

NCT03085147 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

23 participants

A Dye for the Detection of Cancer of the Tongue and Mouth

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2017-03-15
Completion:: 2027-07-31

Conditions

Oral Squamous Cell Carcinoma (OSCC)

Interventions

DRUG

No Results Yet

NCT03071536 | COMPLETED | NA

360 participants

Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2016-11-25
Completion:: 2026-08-03

Conditions

Kidney Function
Kidney Transplant; Complications
Delayed Graft Function

Interventions

DRUG

No Results Yet

NCT03029884 | COMPLETED | NA

4 participants

Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2017-10-28
Completion:: 2023-09-30

Conditions

Chronic Pain
Post Stroke Pain
Phantom Limb Pain
Spinal Cord Injuries

Interventions

DEVICE

Results Available

NCT02968043 | COMPLETED | NA

42 participants

Efficacy of Physiotherapeutic Scoliosis Specific Exercises in Adolescent Idiopathic Scoliosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2017-02-01
Completion:: 2021-12-31

Conditions

Scoliosis Idiopathic Adolescent

Interventions

OTHER

No Results Yet

NCT02912559 | ACTIVE_NOT_RECRUITING | PHASE3

712 participants

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2017-10-16
Completion:: 2025-02-04

Conditions

Colon Adenocarcinoma
DNA Repair Disorder
Lynch Syndrome
Stage III Colon Cancer AJCC v8

Interventions

PROCEDURE
DRUG
OTHER

Results Available

NCT02839707 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

444 participants

Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2017-06-23
Completion:: 2023-05-09

Conditions

Fallopian Tube High Grade Serous Adenocarcinoma
Ovarian High Grade Serous Adenocarcinoma
Ovarian Seromucinous Carcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Fallopian Tube Clear Cell Adenocarcinoma
Recurrent Fallopian Tube Endometrioid Adenocarcinoma
Recurrent Fallopian Tube Undifferentiated Carcinoma
Recurrent Ovarian Carcinoma
Recurrent Ovarian Clear Cell Adenocarcinoma
Recurrent Ovarian Endometrioid Adenocarcinoma
Recurrent Ovarian Undifferentiated Carcinoma
Recurrent Platinum-Resistant Fallopian Tube Carcinoma
Recurrent Platinum-Resistant Ovarian Carcinoma
Recurrent Platinum-Resistant Primary Peritoneal Carcinoma
Recurrent Primary Peritoneal Carcinoma
Recurrent Primary Peritoneal Clear Cell Adenocarcinoma
Recurrent Primary Peritoneal Endometrioid Adenocarcinoma
Recurrent Primary Peritoneal Undifferentiated Carcinoma

Interventions

DRUG
BIOLOGICAL
PROCEDURE
OTHER

Results Available

NCT02698293 | WITHDRAWN | PHASE1

0 participants

PDT Plus Vitamin D3 for Anal Dysplasia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2019-12-01
Completion:: 2022-08-03

Conditions

Anal Dysplasia
Carcinoma in Situ

Interventions

DRUG
OTHER

No Results Yet

NCT02642042 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2016-07-18
Completion:: 2019-05-15

Conditions

KRAS Gene Mutation
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Non-Small Cell Cancer AJCC v7

Interventions

DRUG
OTHER

Results Available

NCT02610465 | COMPLETED

148 participants

High Image Matrix CT Reconstruction

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-11-09
Completion:: 2020-03-27

Conditions

Healthy Subjects
Pulmonary-Related Conditions
Cardiac-Related Conditions

No Results Yet

NCT02595944 | ACTIVE_NOT_RECRUITING | PHASE3

903 participants

Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2016-07-22
Completion:: 2026-12-31

Conditions

Stage IB Lung Non-Small Cell Carcinoma AJCC v7
Stage II Lung Non-Small Cell Cancer AJCC v7
Stage IIIA Lung Non-Small Cell Cancer AJCC v7

Interventions

PROCEDURE
BIOLOGICAL
OTHER

No Results Yet

NCT02573753 | RECRUITING | NA

5000 participants

The Effects of Sleep on Human Microbiota: Implications for Health and Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-10-31
Completion:: 2031-12-31

Conditions

Sleep

Interventions

BEHAVIORAL
DIETARY_SUPPLEMENT

No Results Yet

NCT02520609 | COMPLETED

53 participants

Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-10-28
Completion:: 2020-05-14

Conditions

Liver Disease
Fatty Liver

No Results Yet

NCT02507141 | RECRUITING

140 participants

Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-07-21
Completion:: 2027-07-31

Conditions

Head and Neck Cancer
Squamous Cell Carcinoma (SCC) of the Oral Cavity

Interventions

DEVICE

No Results Yet

NCT02498912 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-08-31
Completion:: 2026-08-31

Conditions

Solid Tumors

Interventions

PROCEDURE
DRUG
DEVICE
GENETIC

No Results Yet

NCT02473757 | ENROLLING_BY_INVITATION

1000 participants

Gene Therapy Follow-up Protocol for People Previously Enrolled in CAR-T Cell Studies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-09-24
Completion:: 2034-07-01

Conditions

Lyphoma, B-Cell
Leukemia, B-cell
Multiple Myeloma
Hematologic Malignancies

No Results Yet

NCT02465060 | ACTIVE_NOT_RECRUITING | PHASE2

6452 participants

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-08-17
Completion:: 2026-12-31

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Bladder Carcinoma
Breast Carcinoma
Cervical Carcinoma
Colon Carcinoma
Colorectal Carcinoma
Endometrial Carcinoma
Esophageal Carcinoma
Exocrine Pancreas Carcinoma
Gastric Carcinoma
Glioma
Head and Neck Carcinoma
Hematopoietic and Lymphoid Cell Neoplasm
Kidney Carcinoma
Liver Carcinoma
Lung Carcinoma
Lymphoma
Malignant Uterine Corpus Neoplasm
Malignant Uterine Neoplasm
Melanoma
Multiple Myeloma
Ovarian Carcinoma
Prostate Carcinoma
Rectal Carcinoma
Recurrent Bladder Carcinoma
Recurrent Breast Carcinoma
Recurrent Cervical Carcinoma
Recurrent Colon Carcinoma
Recurrent Colorectal Carcinoma
Recurrent Esophageal Carcinoma
Recurrent Gastric Carcinoma
Recurrent Glioma
Recurrent Head and Neck Carcinoma
Recurrent Liver Carcinoma
Recurrent Lung Carcinoma
Recurrent Lymphoma
Recurrent Malignant Solid Neoplasm
Recurrent Malignant Uterine Corpus Neoplasm
Recurrent Melanoma
Recurrent Multiple Myeloma
Recurrent Ovarian Carcinoma
Recurrent Pancreatic Carcinoma
Recurrent Prostate Carcinoma
Recurrent Rectal Carcinoma
Recurrent Skin Carcinoma
Recurrent Thyroid Gland Carcinoma
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma
Skin Carcinoma
Thyroid Gland Carcinoma

Interventions

DRUG
PROCEDURE
OTHER
BIOLOGICAL

No Results Yet

NCT02339571 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

600 participants

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-11-23
Completion:: 2033-06-30

Conditions

Stage III Cutaneous Melanoma AJCC v7
Stage IV Cutaneous Melanoma AJCC v6 and v7

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT02281747 | ACTIVE_NOT_RECRUITING

521292 participants

Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-04
Start Date:: 2014-10-24
Completion:: 2029-05-30

Conditions

Rheumatoid Arthritis
Ankylosing Spondylitis

No Results Yet

NCT02257528 | ACTIVE_NOT_RECRUITING | PHASE2

26 participants

Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-05-18
Completion:: 2019-03-05

Conditions

Cervical Adenocarcinoma
Cervical Adenosquamous Carcinoma
Recurrent Cervical Carcinoma
Stage IV Cervical Cancer AJCC v6 and v7
Stage IVA Cervical Cancer AJCC v6 and v7
Stage IVB Cervical Cancer AJCC v6 and v7

Interventions

OTHER
BIOLOGICAL

Results Available

NCT02224781 | ACTIVE_NOT_RECRUITING | PHASE3

267 participants

Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-09-08
Completion:: 2023-09-30

Conditions

Clinical Stage III Cutaneous Melanoma AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Metastatic Melanoma
Recurrent Melanoma
Unresectable Melanoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL
OTHER

Results Available

NCT02213926 | ACTIVE_NOT_RECRUITING | PHASE2

124 participants

An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-03-02
Completion:: 2020-12-04

Conditions

Mantle Cell Lymphoma (MCL)

Interventions

DRUG

Results Available

NCT02211768 | COMPLETED | PHASE1

10 participants

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2014-12-08
Completion:: 2017-09-05

Conditions

Neurofibromatosis
MPNST

Interventions

PROCEDURE
DRUG

No Results Yet

NCT02196181 | ACTIVE_NOT_RECRUITING | PHASE2

280 participants

Testing Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has Spread

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2014-09-19
Completion:: 2027-03-15

Conditions

Stage III Cutaneous Melanoma AJCC v7
Stage IV Cutaneous Melanoma AJCC v6 and v7
Unresectable Melanoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT02143414 | ACTIVE_NOT_RECRUITING | PHASE2

53 participants

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2015-06-30
Completion:: 2022-06-01

Conditions

Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
Recurrent Acute Lymphoblastic Leukemia
Refractory Acute Lymphoblastic Leukemia

Interventions

PROCEDURE
BIOLOGICAL
DRUG

Results Available

NCT02115282 | ACTIVE_NOT_RECRUITING | PHASE3

608 participants

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2014-03-29
Completion:: 2020-05-05

Conditions

Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Breast Adenocarcinoma
HER2/Neu Negative
Locally Advanced Breast Carcinoma
Metastatic Breast Carcinoma
Recurrent Breast Carcinoma

Interventions

PROCEDURE
DRUG
OTHER

Results Available

NCT02101788 | COMPLETED | PHASE2/PHASE3

260 participants

Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2014-04-11
Completion:: 2019-04-04

Conditions

Borderline Ovarian Serous Tumor
Micropapillary Serous Carcinoma
Ovarian Serous Adenocarcinoma
Primary Peritoneal Serous Adenocarcinoma
Recurrent Ovarian Low Grade Serous Adenocarcinoma
Recurrent Primary Peritoneal Serous Adenocarcinoma

Interventions

DRUG
OTHER

Results Available

NCT02075463 | TERMINATED | PHASE2

15 participants

Study to Evaluate the Safety and Efficacy of GSK1278863 in Recombinant Human Erythropoietin (rhEPO) Hyporesponsive Hemodialysis-dependent Chronic Kidney Disease Subjects With Anemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2014-06-11
Completion:: 2016-03-16

Conditions

Anemia
Anaemia

Interventions

DRUG

Results Available

NCT02048813 | ACTIVE_NOT_RECRUITING | PHASE3

529 participants

Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2014-03-10
Completion:: 2018-10-24

Conditions

Anemia
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

DRUG
OTHER
BIOLOGICAL

Results Available

NCT02003222 | ACTIVE_NOT_RECRUITING | PHASE3

488 participants

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2014-05-19
Completion:: 2023-06-23

Conditions

Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

Interventions

PROCEDURE
DRUG
BIOLOGICAL

Results Available

NCT01933620 | ENROLLING_BY_INVITATION

250 participants

Studies of the Human Microbiome in Clinical Center Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-04
Start Date:: 2014-01-28
Completion:: 2028-10-16

Conditions

Multidrug-resistant Colonization

No Results Yet

NCT01900132 | RECRUITING | NA

275 participants

Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2013-06-20
Completion:: 2027-06-01

Conditions

Neuromuscular Disease
Motor Neuron Disease
Inherited Neuromuscular Conditions
Inherited Neuropathies

Interventions

DEVICE

No Results Yet

NCT01845883 | WITHDRAWN | NA

0 participants

Perceptual Decision Making Under Conditions of Visual Uncertainty

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2013-04-30
Completion:: 2015-12-31

Conditions

Parkinson's Disease
Dystonia
Ataxia

Interventions

PROCEDURE

No Results Yet

NCT01639508 | RECRUITING | PHASE2

86 participants

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2012-07-31
Completion:: 2027-07-31

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT01524549 | COMPLETED

178 participants

Blood Vessel Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-04
Start Date:: 2012-03-01

Conditions

Cardiovascular Disease

No Results Yet

NCT01445288 | COMPLETED

76 participants

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-04
Start Date:: 2006-12-05

Conditions

Diffuse Intrinsic Pontine Glioma
PNET
Ependymoma
Germinoma
Medulloblastoma

No Results Yet

NCT01439659 | ACTIVE_NOT_RECRUITING | PHASE2

75 participants

Juice Plus+ and Juice Plus+ Complete in Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2003-02-18
Completion:: 2028-03-01

Conditions

Ovarian Cancer

Interventions

BEHAVIORAL
DIETARY_SUPPLEMENT

No Results Yet

NCT01399385 | RECRUITING | NA

4000 participants

New Heart Imaging Techniques to Evaluate Possible Heart Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2011-07-06
Completion:: 2028-11-06

Conditions

Healthy
Obesity
Diabetes
Healthy Volunteers
Atherosclerosis

Interventions

DEVICE

No Results Yet

NCT01386385 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

53 participants

Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-04
Start Date:: 2011-06-20
Completion:: 2019-05-26

Conditions

Lung Adenocarcinoma
Lung Adenocarcinoma, Mixed Subtype
Lung Large Cell Carcinoma
Lung Squamous Cell Carcinoma
Minimally Invasive Lung Adenocarcinoma
Stage III Lung Non-Small Cell Cancer AJCC v7
Stage IIIA Lung Non-Small Cell Cancer AJCC v7
Stage IIIB Lung Non-Small Cell Cancer AJCC v7

Interventions

RADIATION
DRUG
OTHER

Results Available

NCT01352975 | COMPLETED

217 participants

Study of Dark Adaptation in Age-Related Macular Degeneration

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-04
Start Date:: 2011-05-16

Conditions

Age-Related Macular Degeneration

No Results Yet