Clinical Trials

NCT05316155 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

235 participants

Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-04-11

Completion:

2028-03-30

Conditions

• Non-Muscle Invasive Bladder Neoplasms

Interventions

• DRUG

No Results Yet

NCT05313256 | COMPLETED | PHASE2/PHASE3

65 participants

Quick Epidural Top-up With Alkalinized Lidocaine for Emergent Caesarean Delivery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-07-14

Completion:

2024-07-08

Conditions

• Obstetric Labor Complications

Interventions

• DRUG

No Results Yet

NCT05304767 | COMPLETED | PHASE3

290 participants

An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-03-07

Completion:

2026-03-25

Conditions

• Schizophrenia

Interventions

• DRUG

No Results Yet

NCT05303467 | RECRUITING | PHASE1

36 participants

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-07-30

Completion:

2026-10-31

Conditions

• Glioblastoma Multiforme
• Recurrent Glioblastoma

Interventions

• DEVICE

No Results Yet

NCT05291091 | ACTIVE_NOT_RECRUITING | PHASE2

244 participants

Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-11-10

Completion:

2026-09-30

Conditions

• Becker Muscular Dystrophy

Interventions

• DRUG

No Results Yet

NCT05283421 | RECRUITING | NA

150 participants

Improving Diagnostics in Cervical Dysplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-08-23

Completion:

2026-08-01

Conditions

• Cervical Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05279027 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

6 participants

Zr89 + PET Companion Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-03-08

Completion:

2026-07-31

Conditions

• Melanoma (Skin)

Interventions

• DRUG

No Results Yet

NCT05274425 | ACTIVE_NOT_RECRUITING

683 participants

A 24-week rPMS Study in Real-world Setting for Enerzair

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2022-05-09

Completion:

2026-12-23

Conditions

• Asthma

Interventions

• OTHER

No Results Yet

NCT05265273 | RECRUITING | PHASE2/PHASE3

12 participants

A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-07-20

Completion:

2027-06-30

Conditions

• Myasthenia Gravis

Interventions

• DRUG

No Results Yet

NCT05242484 | ACTIVE_NOT_RECRUITING | PHASE2

577 participants

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-09-19

Completion:

2025-05-15

Conditions

• Colitis, Ulcerative

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05217446 | ACTIVE_NOT_RECRUITING | PHASE2

108 participants

A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-07-11

Completion:

2026-06-19

Conditions

• Metastatic Colorectal Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05213598 | RECRUITING

100 participants

Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity Assessment

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2022-09-07

Completion:

2051-06-30

Conditions

• Congenital Heart Disease

No Results Yet

NCT05203939 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

22 participants

Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-01-24

Completion:

2027-03-31

Conditions

• Retinitis Pigmentosa
• Leber Congenital Amaurosis

Interventions

• DRUG

No Results Yet

NCT05179876 | RECRUITING | PHASE3

280 participants

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-05-04

Completion:

2027-01-31

Conditions

• Hypertension, Pulmonary

Interventions

• DRUG

No Results Yet

NCT05179538 | ACTIVE_NOT_RECRUITING | NA

120 participants

Genetic and Cognitive Predictors of Aphasia Treatment Response

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2020-10-23

Completion:

2026-07-01

Conditions

• Aphasia

Interventions

• BEHAVIORAL

No Results Yet

NCT05169333 | RECRUITING

250000 participants

The Oxford Risk Factors And Non-Invasive Imaging Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2016-02-23

Completion:

2030-02-28

Conditions

• Cardiovascular Diseases
• Cardiovascular Risk Factors

No Results Yet

NCT05164471 | TERMINATED | PHASE1/PHASE2

6 participants

Phase 1/2 Dose Confirmation Study of FLT180a in Hemophilia B

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2021-12-06

Completion:

2023-05-31

Conditions

• Hemophilia B

Interventions

• GENETIC

Results Available

NCT05163171 | COMPLETED

122 participants

Prevalence of the Victimization and the Perpetration of Intimate Partner Violence Among the Patients From Puy-de-Dôme and Paris Consulting or Being Hospitalized for Addiction Problems and Their Expectations From General Practitioners (VIA-MG)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2022-01-10

Completion:

2022-07-20

Conditions

• Addiction
• Violence, Domestic

Interventions

• OTHER

No Results Yet

NCT05160948 | COMPLETED

105 participants

Change in Knowledge After Receiving Personal Air Pollution Results

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2021-11-10

Completion:

2022-11-10

Conditions

• Environmental Exposure

Interventions

• OTHER

Results Available

NCT05157477 | RECRUITING | NA

90 participants

Targeting the Sensory Disturbance in Autism Spectrum Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2020-06-17

Completion:

2027-12-31

Conditions

• Autistic Disorders Spectrum

Interventions

• BEHAVIORAL

No Results Yet

NCT05138133 | ACTIVE_NOT_RECRUITING | PHASE3

363 participants

Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-02-15

Completion:

2027-02-23

Conditions

• Lupus Nephritis

Interventions

• DRUG

No Results Yet

NCT05130788 | COMPLETED | NA

150 participants

WeChat Quit Coach Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-02-10

Completion:

2025-01-15

Conditions

• Smoking Cessation

Interventions

• BEHAVIORAL
• DRUG

Results Available

NCT05092269 | ACTIVE_NOT_RECRUITING | PHASE3

159 participants

A Long-term Extension Study of Ustekinumab in Pediatric Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2021-10-18

Completion:

2027-09-29

Conditions

• Crohn Disease
• Colitis, Ulcerative
• Arthritis, Psoriatic

Interventions

• DRUG

No Results Yet

NCT05090033 | COMPLETED

103 participants

Characterizing the Use of Ofatumumab in a Real World Setting

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2022-12-08

Completion:

2026-02-06

Conditions

• Relapsing Multiple Sclerosis

Interventions

• OTHER

No Results Yet

NCT05083182 | COMPLETED | PHASE3

48 participants

A Study of Ustekinumab or Guselkumab in Pediatric Participants With Active Juvenile Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-08-30

Completion:

2026-01-12

Conditions

• Arthritis, Juvenile

Interventions

• DRUG

No Results Yet

NCT05067283 | RECRUITING | PHASE1

830 participants

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2021-12-17

Completion:

2030-02-25

Conditions

• Advanced Solid Tumors

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05063565 | ACTIVE_NOT_RECRUITING | PHASE2

100 participants

TheraSphere With Durvalumab and Tremelimumab for HCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-11-03

Completion:

2027-06-30

Conditions

• Hepatocellular Carcinoma

Interventions

• DEVICE
• DRUG

No Results Yet

NCT05063552 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

430 participants

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-03-13

Completion:

2027-12-15

Conditions

• Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Metastatic Head and Neck Squamous Cell Carcinoma
• Metastatic Hypopharyngeal Squamous Cell Carcinoma
• Metastatic Laryngeal Squamous Cell Carcinoma
• Metastatic Lip and Oral Cavity Carcinoma
• Metastatic Nasal Cavity Squamous Cell Carcinoma
• Metastatic Nasopharyngeal Squamous Cell Carcinoma
• Metastatic Pharyngeal Squamous Cell Carcinoma
• Metastatic Sinonasal Squamous Cell Carcinoma
• Recurrent Head and Neck Squamous Cell Carcinoma
• Recurrent Hypopharyngeal Squamous Cell Carcinoma
• Recurrent Laryngeal Squamous Cell Carcinoma
• Recurrent Lip and Oral Cavity Squamous Cell Carcinoma
• Recurrent Nasopharyngeal Squamous Cell Carcinoma
• Recurrent Pharyngeal Squamous Cell Carcinoma
• Recurrent Sinonasal Squamous Cell Carcinoma
• Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
• Stage IV Hypopharyngeal Carcinoma AJCC v8
• Stage IV Laryngeal Cancer AJCC v8
• Stage IV Lip and Oral Cavity Cancer AJCC v8
• Stage IV Nasopharyngeal Carcinoma AJCC v8
• Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
• Stage IV Sinonasal Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT05058651 | SUSPENDED | PHASE2/PHASE3

189 participants

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-06-28

Completion:

2028-10-01

Conditions

• Advanced Extrapulmonary Neuroendocrine Carcinoma
• Metastatic Extrapulmonary Neuroendocrine Carcinoma
• Recurrent Extrapulmonary Neuroendocrine Carcinoma
• Unresectable Extrapulmonary Neuroendocrine Carcinoma

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT05054829 | RECRUITING | NA

160 participants

Establishment of Social Skills Training Group in Adults With Autism Spectrum Disorder and Effectiveness Analysis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2017-03-01

Completion:

2026-12-31

Conditions

• Social Skill Training Group

Interventions

• BEHAVIORAL

No Results Yet

NCT05049798 | ACTIVE_NOT_RECRUITING

1314 participants

A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2021-08-25

Completion:

2027-08-01

Conditions

• Arthritis, Psoriatic

Interventions

• DRUG

No Results Yet

NCT05045820 | ACTIVE_NOT_RECRUITING | NA

106 participants

Integrative Medicine in Pain Management in Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2021-06-29

Completion:

2025-06-20

Conditions

• Sickle Cell Disease
• Pain
• Acupuncture
• Quantitative Sensory Testing
• Magnetic Resonance Imaging
• Circulating Biomarkers
• Electroencephalography
• Functional Near-infrared Spectroscopy

Interventions

• DEVICE

No Results Yet

NCT05019716 | RECRUITING | PHASE1/PHASE2

36 participants

Testing the Safety and Efficacy of the Addition of a New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment (Cisplatin and Etoposide or Carboplatin and Paclitaxel) for Adult and Pediatric Patients (12-17 Years) With NUT Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-07-13

Completion:

2027-06-07

Conditions

• Advanced NUT Carcinoma
• Metastatic NUT Carcinoma
• Unresectable NUT Carcinoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05017129 | COMPLETED | NA

83 participants

E-training of Inmate Peer Caregivers for Enhancing Geriatric and End-of-life Care in Prisons

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2020-06-15

Completion:

2024-12-19

Conditions

• Aging

Interventions

• BEHAVIORAL

Results Available

NCT04996875 | RECRUITING | PHASE2

140 participants

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2021-11-09

Completion:

2025-09-19

Conditions

• Advanced Systemic Mastocytosis (AdvSM)
• SM With an Associated Hematologic Neoplasm (SM-AHN)
• Mast Cell Leukemia (MCL)
• Aggressive Systemic Mastocytosis (ASM)

Interventions

• DRUG

No Results Yet

NCT04991467 | ACTIVE_NOT_RECRUITING | NA

367 participants

A Multimodal Parent-focused Intervention for Vulnerable Populations in the Bronx

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2021-12-17

Completion:

2026-12-31

Conditions

• Parenting
• Covid19

Interventions

• BEHAVIORAL

No Results Yet

NCT04981509 | RECRUITING | PHASE2

65 participants

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-06-10

Completion:

2027-12-31

Conditions

• Hereditary Leiomyomatosis and Renal Cell Carcinoma
• Papillary Renal Cell Carcinoma
• Renal Cell Carcinoma
• Sporadic Papillary Renal Cell Carcinoma
• Stage III Renal Cell Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT04968249 | ACTIVE_NOT_RECRUITING

200 participants

Michigan Early Disease Progression Cohort

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2021-07-30

Completion:

2026-12-31

Conditions

• COPD

Interventions

• OTHER

No Results Yet

NCT04963153 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-07-07

Completion:

2026-12-01

Conditions

• Locally Advanced Bladder Urothelial Carcinoma
• Locally Advanced Renal Pelvis Urothelial Carcinoma
• Locally Advanced Ureter Urothelial Carcinoma
• Locally Advanced Urethral Urothelial Carcinoma
• Locally Advanced Urothelial Carcinoma
• Metastatic Bladder Urothelial Carcinoma
• Metastatic Renal Pelvis Urothelial Carcinoma
• Metastatic Ureter Urothelial Carcinoma
• Metastatic Urethral Urothelial Carcinoma
• Metastatic Urothelial Carcinoma
• Recurrent Bladder Urothelial Carcinoma
• Recurrent Renal Pelvis Urothelial Carcinoma
• Recurrent Ureter Urothelial Carcinoma
• Recurrent Urethral Urothelial Carcinoma
• Recurrent Urothelial Carcinoma
• Stage IIIB Bladder Cancer AJCC v8
• Stage IV Bladder Cancer AJCC v8
• Stage IV Renal Pelvis Cancer AJCC v8
• Stage IV Ureter Cancer AJCC v8
• Stage IV Urethral Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04929210 | ACTIVE_NOT_RECRUITING | PHASE4

411 participants

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2021-08-30

Completion:

2026-08-04

Conditions

• Arthritis, Psoriatic

Interventions

• DRUG

No Results Yet