Clinical Trials

NCT05384756 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

TMLI and Alemtuzumab for Treatment of Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-07-13

Completion:

2026-12-01

Conditions

• Sickle Cell Disease

Interventions

• DRUG
• PROCEDURE
• RADIATION

No Results Yet

NCT05378035 | RECRUITING

427 participants

DOAC in Chinese Patients With Atrial Fibrillation

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2022-09-28

Completion:

2027-09-27

Conditions

• Atrial Fibrillation
• Stroke
• Stroke, Acute
• Brain Diseases
• Major Adverse Cardiovascular Event
• Arterial Thromboembolism
• Venous Thromboembolism

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05373043 | RECRUITING | NA

300 participants

Long-term COVID and Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-11-01

Completion:

2027-10-31

Conditions

• Long-COVID

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05344469 | RECRUITING

800 participants

A NIS Evaluating Various Injectable and Oral Treatments in Patients With Relapsing Multiple Sclerosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2022-05-10

Completion:

2029-05-30

Conditions

• Relapsing Multiple Sclerosis

Interventions

• OTHER

No Results Yet

NCT05330182 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

375 participants

LMN-201 for Prevention of C. Difficile Infection Recurrence

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2024-08-29

Completion:

2026-08-31

Conditions

• Clostridioides Difficile Infection

Interventions

• DRUG

No Results Yet

NCT05329350 | RECRUITING

50 participants

Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® mVSD Cases

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2022-03-03

Completion:

2031-01-01

Conditions

• Muscular Ventricular Septal Defect

Interventions

• DEVICE

No Results Yet

NCT05327023 | RECRUITING | PHASE1/PHASE2

430 participants

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-05-23

Completion:

2028-07-03

Conditions

• Hematologic Neoplasms

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05312229 | RECRUITING | PHASE1

153 participants

Housing Transitions QUERI

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2021-10-01

Completion:

2026-09-30

Conditions

• Homelessness

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05307874 | TERMINATED | PHASE1/PHASE2

56 participants

Phase 1/2a Study of ICT01 Plus Low Dose SC IL-2 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-05-04

Completion:

2025-10-09

Conditions

• Solid Tumor, Adult

Interventions

• DRUG

No Results Yet

NCT05299294 | ACTIVE_NOT_RECRUITING

160 participants

Observational Study of the Use of 8% Capsaicin Patch in Children 0 to 18 Years Old

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2022-05-12

Completion:

2027-05-31

Conditions

• Neuropathic Pain
• Chronic Pain

Interventions

• OTHER

No Results Yet

NCT05283980 | COMPLETED | PHASE2/PHASE3

62 participants

Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-11-17

Completion:

2024-03-29

Conditions

• Pain, Postoperative
• Pain, Acute
• Pain, Chest
• Pain
• Satisfaction, Patient
• Opioid Use, Unspecified
• Opioids; Harmful Use

Interventions

• DRUG

No Results Yet

NCT05268289 | RECRUITING | PHASE2

240 participants

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-08-10

Completion:

2026-03-19

Conditions

• Lupus Nephritis

Interventions

• DRUG

No Results Yet

NCT05267626 | RECRUITING | PHASE1/PHASE2

159 participants

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-04-04

Completion:

2027-02-28

Conditions

• Advanced Solid Tumor
• Metastatic Cancer
• Cutaneous Melanoma
• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05245136 | RECRUITING

3000 participants

Augsburg Longitudinal Plasma Study for the Evaluation of Liquid Biopsy as Diagnostic Tool.

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2021-03-29

Completion:

2029-11-30

Conditions

• Characteristics Disease
• Metastatic Cancer
• Solid Tumor

No Results Yet

NCT05175105 | ACTIVE_NOT_RECRUITING | PHASE3

30 participants

A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Not Regularly Transfused, Followed by a 5-Year Extension Period

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-06-06

Completion:

2024-12-13

Conditions

• Pediatric Pyruvate Kinase Deficiency
• Pediatric Hemolytic Anemia

Interventions

• DRUG

No Results Yet

NCT05154487 | ACTIVE_NOT_RECRUITING | PHASE2

51 participants

A Study of Alpelisib and Fulvestrant to Treat Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2024-09-11

Completion:

2028-05-01

Conditions

• Endometroid Endometrial Cancer

Interventions

• DRUG

No Results Yet

NCT05153252 | ACTIVE_NOT_RECRUITING | NA

128 participants

Timing Intervention of Morning Versus Evening Exercise

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2021-12-07

Completion:

2027-03-31

Conditions

• Overweight and Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT05144256 | ACTIVE_NOT_RECRUITING | PHASE3

49 participants

A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-06-08

Completion:

2024-05-03

Conditions

• Pediatric Pyruvate Kinase Deficiency
• Pediatric Hemolytic Anemia

Interventions

• DRUG

No Results Yet

NCT05125302 | RECRUITING | PHASE3

1059 participants

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-01-13

Completion:

2027-05-31

Conditions

• Migraine

Interventions

• DRUG

No Results Yet

NCT05078905 | ACTIVE_NOT_RECRUITING

103 participants

Vaccine Responses to SARS-CoV-2 and Other Emerging Infectious Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2021-10-13

Completion:

2050-01-01

Conditions

• COVID-19
• Vaccination
• Healthy Volunteer

No Results Yet

NCT05069688 | RECRUITING | PHASE1

20 participants

Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2023-07-07

Completion:

2026-12-31

Conditions

• Pediatric HIV Infection
• Tuberculosis Infection

Interventions

• DRUG

No Results Yet

NCT05047913 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

20 participants

Comprehensive Evaluation of Tumor Oxygenation, Metabolism and Blood Supply of High Grade Glioma and Cervical Cancers Using Dynamic FAZA PET and Multiparametric MR

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2021-09-20

Completion:

2027-02-02

Conditions

• Brain Tumor
• Cervical Cancer

Interventions

• DRUG

No Results Yet

NCT05039632 | RECRUITING | PHASE1/PHASE2

40 participants

Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2023-05-08

Completion:

2028-02-01

Conditions

• Advanced Malignant Solid Neoplasm
• Metastatic Malignant Neoplasm in the Liver
• Metastatic Malignant Neoplasm in the Lung
• Metastatic Malignant Solid Neoplasm

Interventions

• RADIATION
• OTHER

No Results Yet

NCT05032053 | RECRUITING

3000 participants

Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2022-03-01

Completion:

2027-12-01

Conditions

• Ischemic Stroke

Interventions

• DRUG

No Results Yet

NCT04996823 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

Axitinib + Ipilimumab in Advanced Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2021-08-04

Completion:

2026-08-20

Conditions

• Melanoma

Interventions

• DRUG

No Results Yet

NCT04994132 | ACTIVE_NOT_RECRUITING | PHASE3

113 participants

A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2021-09-14

Completion:

2026-06-30

Conditions

• Alveolar Rhabdomyosarcoma
• Botryoid-Type Embryonal Rhabdomyosarcoma
• Embryonal Rhabdomyosarcoma
• Metastatic Embryonal Rhabdomyosarcoma
• Metastatic Rhabdomyosarcoma
• Solid Alveolar Rhabdomyosarcoma
• Spindle Cell Rhabdomyosarcoma
• Spindle Cell/Sclerosing Rhabdomyosarcoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT04992195 | COMPLETED

415 participants

Impact of COVID-19 Vaccines on Cerebrovascular Health

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2021-07-05

Completion:

2026-03-31

Conditions

• Stroke
• Stroke, Acute
• Stroke, Ischemic
• Dementia
• Brain Ischemia
• Alzheimer Disease
• Brain Diseases
• Major Adverse Cardiovascular Event
• Arterial Thromboembolism
• Venous Thromboembolism

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04991870 | RECRUITING | PHASE1

25 participants

Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2023-04-28

Completion:

2027-01-31

Conditions

• Recurrent Gliosarcoma
• Recurrent Supratentorial Glioblastoma
• Supratentorial Gliosarcoma

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT04975919 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2021-09-29

Completion:

2027-05-31

Conditions

• Recurrent Acute Biphenotypic Leukemia
• Recurrent Acute Myeloid Leukemia
• Refractory Acute Biphenotypic Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT04973423 | RECRUITING | NA

180 participants

STUDY OF THE ADDED VALUE OF A TRANSMURAL EVALUATION IN PATIENTS WITH CROHN'S DISEASE UNDER BIOTHERAPY WITH CLOSE FECAL CALPROTECTIN FOLLOW-UP

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-03-21

Completion:

2027-03-21

Conditions

• Crohn Disease
• Calprotectin
• MRI

Interventions

• RADIATION

No Results Yet

NCT04949659 | COMPLETED | NA

250 participants

Low vs Medium Pressure Pneumoperitoneum

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2021-09-27

Completion:

2026-07-23

Conditions

• Appendicitis Acute

Interventions

• PROCEDURE

No Results Yet

NCT04939090 | ACTIVE_NOT_RECRUITING | PHASE3

227 participants

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-01-03

Completion:

2026-04-14

Conditions

• Advanced Malignant Solid Neoplasm
• Anorexia
• Hematopoietic and Lymphoid Cell Neoplasm

Interventions

• DRUG
• OTHER

No Results Yet

NCT04935606 | COMPLETED | NA

457 participants

mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2021-06-01

Completion:

2026-06-30

Conditions

• Drug Use

Interventions

• BEHAVIORAL

No Results Yet

NCT04927429 | RECRUITING

3400 participants

Technical Development of Cardiovascular Magnetic Resonance Imaging

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2024-04-08

Completion:

2026-08-31

Conditions

• Cardiovascular Disease

No Results Yet

NCT04879940 | ACTIVE_NOT_RECRUITING | PHASE2

17 participants

Phase II Study to Evaluate the Safety and Efficacy of Prostatic Artery Embolization

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-02-23

Completion:

2026-06-16

Conditions

• Prostate Carcinoma
• Benign Prostatic Hyperplasia

Interventions

• RADIATION
• DEVICE

No Results Yet

NCT04857255 | COMPLETED | NA

143 participants

Technology-assisted Language Intervention (TALI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2020-10-15

Completion:

2025-12-26

Conditions

• Hearing Loss, Bilateral
• Language Development

Interventions

• BEHAVIORAL

No Results Yet

NCT04831580 | RECRUITING | NA

840 participants

A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2022-03-22

Completion:

2029-03-31

Conditions

• Cervical Cancer

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04804748 | RECRUITING

450 participants

The DefiPace Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2023-03-28

Completion:

2027-09-30

Conditions

• Post-operative Atrial Fibrillation POAF

Interventions

• OTHER

No Results Yet

NCT04804332 | RECRUITING | NA

244 participants

Removal of Intrauterine Retained Products of Conception (RPOC) After Miscarriage Guided by Hysteroscopy Trial. A Randomized Controlled Trial.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-30

Start Date:

2021-07-12

Completion:

2029-12-31

Conditions

• Retained Products of Conception

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04794829 | COMPLETED

75 participants

Natural History of Systemic and Nasal Mucosal Immunity to Influenza and SARS-CoV-2 in Adults After Vaccination

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-30

Start Date:

2021-08-19

Completion:

2026-07-28

Conditions

• COVID-19
• Influenza

No Results Yet