Clinical Trials

NCT05345444 | ACTIVE_NOT_RECRUITING | NA

48 participants

Radiation Therapy and IRreversible Electroporation for Intermediate Risk Prostate Cancer (RTIRE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-05-26
Completion:: 2026-04-24

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT05338632 | TERMINATED | PHASE1

58 participants

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-06-24
Completion:: 2026-03-23

Conditions

Opioid Induced Respiratory Depression
Chronic Opioid Use

Interventions

DRUG

No Results Yet

NCT05334368 | RECRUITING | PHASE3

123 participants

Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-09-06
Completion:: 2028-12-19

Conditions

Hypereosinophilic Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT05329766 | ACTIVE_NOT_RECRUITING | PHASE2

332 participants

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-06-10
Completion:: 2027-01-31

Conditions

Gastrointestinal Tract Malignancies

Interventions

DRUG

No Results Yet

NCT05327465 | RECRUITING | NA

62 participants

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-08-11
Completion:: 2026-12-31

Conditions

Androgen Deprivation Therapy
Prostate Cancer
Prostate Cancer Metastatic

Interventions

OTHER

No Results Yet

NCT05322577 | TERMINATED | PHASE1/PHASE2

72 participants

A Study Evaluating Bemarituzumab in Combination With Other Anti-cancer Therapies in Subjects With Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-05-17
Completion:: 2025-11-21

Conditions

Gastric Cancer
Gastroesophageal Junction Cancer

Interventions

DRUG

No Results Yet

NCT05284643 | RECRUITING | NA

96 participants

Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-09-30
Completion:: 2027-09-30

Conditions

Recurrent Glioblastoma

Interventions

RADIATION
DRUG

No Results Yet

NCT05269004 | ACTIVE_NOT_RECRUITING | PHASE3

1300 participants

A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-05-03
Completion:: 2027-12-31

Conditions

Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT05258279 | COMPLETED | PHASE2

30 participants

Lenvatinib in Combination With Carboplatin Pemetrexed and Pembrolizumab for NSCLC With EGFR Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-07-01
Completion:: 2023-10-31

Conditions

Non-squamous Non-small-cell Lung Cancer
EGFR Activating Mutation

Interventions

DRUG

No Results Yet

NCT05247684 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

AK112 Neoadjuvant/Adjuvant Treatment for Resectable NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-02-20
Completion:: 2025-08-18

Conditions

Resectable Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05196373 | WITHDRAWN | PHASE1/PHASE2

0 participants

Safety, Tolerability, Pharmacokinetics, Immunogenicity and Efficacy of STP705 in Adult Patients With Hypertrophic Scars

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-12-07
Completion:: 2022-06-30

Conditions

Hypertrophic Scar

Interventions

DRUG

No Results Yet

NCT05188118 | COMPLETED | EARLY_PHASE1

10 participants

Rapid Sequencing of Approved Therapies in Patients With Metastatic or Unresectable Clear Cell Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2023-02-15
Completion:: 2026-06-05

Conditions

Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT05178368 | COMPLETED

202 participants

MRI in Randomised Cohorts of Asymptomatic AS

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-07-28
Completion:: 2025-11-27

Conditions

Aortic Stenosis, Severe

Interventions

PROCEDURE

No Results Yet

NCT05156398 | RECRUITING | PHASE3

640 participants

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-02-28
Completion:: 2031-11-29

Conditions

Migraine

Interventions

DRUG

No Results Yet

NCT05156151 | ENROLLING_BY_INVITATION | NA

35 participants

Stromal Lenticule Implantation for Management of Herpetic Stromal Keratitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2017-01-01
Completion:: 2020-01-01

Conditions

Stromal Keratitis

Interventions

OTHER

No Results Yet

NCT05150990 | COMPLETED | NA

186 participants

Technology and Family Thriving Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-10-02
Completion:: 2024-03-16

Conditions

Alzheimer Disease
Dementia
Caregiver Burnout
Quality of Life
Mental Health Wellness 1
Loneliness
Family Relationship

Interventions

BEHAVIORAL

Results Available

NCT05144789 | COMPLETED | NA

70 participants

Personalized Therapeutic Neuromodulation for Anhedonic Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-05-31
Completion:: 2025-06-06

Conditions

Treatment Resistant Depression

Interventions

DEVICE

Results Available

NCT05141890 | ACTIVE_NOT_RECRUITING | NA

39 participants

Probiotics for Inflammation in Pediatric Chronic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-04-25
Completion:: 2024-08-01

Conditions

Chronic Pain
Body Mass Index >=85th Percentile

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05125029 | COMPLETED | PHASE4

24 participants

Botulinum Toxin in Raynaud's Phenomenon

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-02-10
Completion:: 2025-05-15

Conditions

Raynaud Phenomenon

Interventions

DRUG

Results Available

NCT05123014 | ACTIVE_NOT_RECRUITING | NA

45 participants

Lenticule Implantation and Autologous Serum New Approach in Treatment of Adenoviral Keratitis Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-02-01
Completion:: 2019-02-01

Conditions

Adenoviral Keratoconjunctivitis

Interventions

OTHER

No Results Yet

NCT05115058 | ENROLLING_BY_INVITATION | NA

41 participants

A New Successful Approach for Emmetropic Presbyopic Patients Using Intrastromal Pocket With Smile Module

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2016-06-01
Completion:: 2018-06-01

Conditions

Presbyopia

Interventions

OTHER

No Results Yet

NCT05081180 | TERMINATED | PHASE1

17 participants

Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-12-03
Completion:: 2026-02-11

Conditions

Central Nervous System Tumors

Interventions

DRUG

No Results Yet

NCT05069974 | COMPLETED | PHASE3

165 participants

Alternative Antibiotics for Syphilis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-10-14
Completion:: 2026-04-15

Conditions

Early Latent Syphilis
Primary Syphilis
Secondary Syphilis

Interventions

DRUG

No Results Yet

NCT05045950 | RECRUITING | PHASE2

53 participants

Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-11-17
Completion:: 2028-05-31

Conditions

Brain Metastases

Interventions

DRUG
RADIATION

No Results Yet

NCT05043051 | COMPLETED | NA

80 participants

Autoimmune Basis for Postural Tachycardia Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-01-14
Completion:: 2026-02-28

Conditions

Postural Tachycardia Syndrome

Interventions

DEVICE

No Results Yet

NCT05037149 | COMPLETED | PHASE1

50 participants

Ph. 1, Evaluation of Safety, Tolerability, PK, Anti-tumor Activity of STP707 IV in Subjects With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-11-01
Completion:: 2024-04-25

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT05024097 | RECRUITING | PHASE2

43 participants

A Phase I-II Study to Test the Safety and Efficacy of PD1 (AB122) and Adenosine Receptor (AB928) Antagonists With Chemotherapy After Short-Course Radiation for Rectal Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-03-31
Completion:: 2026-12-31

Conditions

Rectal Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT05023551 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

39 participants

Study of DSP-0390 in Patients With Recurrent High-Grade Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-09-08
Completion:: 2027-09-30

Conditions

High Grade Glioma
Glioblastoma Multiforme

Interventions

DRUG

No Results Yet

NCT05019027 | COMPLETED | PHASE4

14 participants

N-of-1 for Beta-Blockers in Cardiac Amyloidosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2024-01-31
Completion:: 2026-06-04

Conditions

Cardiac Amyloidosis
Heart Diseases
TTR Cardiac Amyloidosis

Interventions

DRUG

No Results Yet

NCT05015348 | COMPLETED | NA

127 participants

Effect of Omega-3 Supplementation on Fasting Triglycerides During Lifestyle Intervention in Adults With Mild-to-moderate Hypertriglyceridemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-12-01
Completion:: 2023-12-01

Conditions

Hyperlipidemias

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT05011006 | TERMINATED

8 participants

NT-3 Levels and Function in Individuals With CMT

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2020-01-29
Completion:: 2020-11-21

Conditions

Charcot-Marie-Tooth Disease
Peripheral Neuropathy
Chronic Inflammatory Demyelinating Polyneuropathy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04990609 | RECRUITING | PHASE2

60 participants

EUS-RFA PANCARDINAL-1 Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-08-13
Completion:: 2026-12-01

Conditions

Pancreatic Ductal Adenocarcinoma (PDAC)

Interventions

DEVICE
DRUG

No Results Yet

NCT04987060 | ACTIVE_NOT_RECRUITING | NA

24 participants

Intrastromal Fresh Human Corneal Lenticule Implantation Using Smile Surgery for Treatment of Irregular Corneal Astigmatism After Penetrating Keratoplasty (New Approach)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2017-03-01
Completion:: 2021-03-01

Conditions

Irregular Astigmatism

Interventions

DEVICE

No Results Yet

NCT04978428 | COMPLETED | PHASE2

4 participants

Epidiolex in Obsessive Compulsive Disorder and Related Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-04-14
Completion:: 2025-11-01

Conditions

Obsessive-Compulsive Disorder
Trichotillomania (Hair-Pulling Disorder)
Tourette Syndrome
Hoarding Disorder

Interventions

DRUG

Results Available

NCT04974944 | TERMINATED | PHASE2

35 participants

First-line Treatment With Camrelizumab + Apatinib Versus Chemotherapy + Bevacizumab in Advanced Cervical Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-07-30
Completion:: 2024-01-08

Conditions

Stage IVB Cervical Cancer
Recurrent Cervical Cancer
Persistent Cervical Cancer

Interventions

DRUG

No Results Yet

NCT04936321 | COMPLETED | NA

224 participants

Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-10-01
Completion:: 2026-03-12

Conditions

Insomnia
Migraine Disorders
Headache Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT04889924 | RECRUITING | NA

820 participants

ALND vs ART in Positive Sentinel Node After Neoadjuvant Therapy in Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-06-11
Completion:: 2026-12-31

Conditions

Breast Cancer
Chemotherapy
Sentinel Lymph Node
Axillary Lymph Nodes Dissection
Radiotherapy Side Effect

Interventions

RADIATION
PROCEDURE

No Results Yet

NCT04850105 | ACTIVE_NOT_RECRUITING

202 participants

A Non-interventional Cohort Safety Study of Patients With hATTR-PN

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-09-21
Completion:: 2036-03-31

Conditions

Hereditary Transthyretin Amyloidosis With Polyneuropthy

Interventions

OTHER

No Results Yet

NCT04848740 | ENROLLING_BY_INVITATION | NA

100 participants

Human Fresh Corneal Lenticule Implantation Criteria in Progressive Corneal Disease Using Relex-Smile

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-02-01
Completion:: 2027-02-01

Conditions

Progressive Disease of Corneae

Interventions

DEVICE

No Results Yet

NCT04840602 | RECRUITING | PHASE2

92 participants

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2022-01-05
Completion:: 2028-03-31

Conditions

Lymphoplasmacytic Lymphoma
Waldenstrom Macroglobulinemia

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet