Clinical Trials

NCT03899155 | RECRUITING | PHASE2

1500 participants

Pan Tumor Rollover Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-08-09

Completion:

2029-08-25

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT03880461 | COMPLETED | NA

1335 participants

A Mobile Health Intervention to Achieve Appropriate Gestational Weight Gain in Overweight/Obese Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2021-01-21

Completion:

2024-03-28

Conditions

• Gestational Weight Gain

Interventions

• BEHAVIORAL

Results Available

NCT03878459 | ACTIVE_NOT_RECRUITING | PHASE4

120 participants

Dapagliflozin Plus Pioglitazone in T1DM

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-08-08

Completion:

2026-03-15

Conditions

• Type 1 Diabetes Mellitus

Interventions

• DRUG

No Results Yet

NCT03868670 | ACTIVE_NOT_RECRUITING | NA

6 participants

Responsive Neurostimulation For Loss Of Control Eating

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-04-10

Completion:

2028-01-01

Conditions

• Loss of Control Eating
• Obesity, Morbid

Interventions

• DEVICE

No Results Yet

NCT03855917 | RECRUITING | PHASE4

30 participants

Strategic Treatment Reduction in Very Early Liver Disease With 4 Weeks Sofosbuvir Plus Glecepravir-pibrentasvir

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2020-02-11

Completion:

2029-07-31

Conditions

• Hepatitis C

Interventions

• DRUG

No Results Yet

NCT03838978 | COMPLETED | NA

81 participants

Calypso Knee System Clinical Study, OUS

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-02-08

Completion:

2022-01-17

Conditions

• Osteoarthritis, Knee

Interventions

• DEVICE

Results Available

NCT03785249 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

731 participants

Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-01-15

Completion:

2026-06-23

Conditions

• Advanced Cancer
• Metastatic Cancer
• Malignant Neoplastic Disease

Interventions

• DRUG

No Results Yet

NCT03742037 | COMPLETED | PHASE2

427 participants

Efficacy and Safety of Four Doses of Cenerimod Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-12-21

Completion:

2021-08-31

Conditions

• Systemic Lupus Erythematosus

Interventions

• DRUG

Results Available

NCT03729778 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

100 participants

Impact of HIV-1 and Aging on Mucosal Vaccine Responses

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2017-01-18

Completion:

2020-03-31

Conditions

• HIV-1-infection
• Human Immunodeficiency Virus
• HIV/AIDS
• HIV Infections

Interventions

• BIOLOGICAL

No Results Yet

NCT03716167 | RECRUITING | NA

20 participants

Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-07-27

Completion:

2027-10-31

Conditions

• Venous Leg Ulcer

Interventions

• DEVICE

No Results Yet

NCT03704766 | RECRUITING | NA

442 participants

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2016-06-28

Completion:

2026-11-30

Conditions

• Joint Infection
• Infection of Hip Joint (Disorder)
• Infection of Shoulder Joint
• Septic Arthritis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03695250 | TERMINATED | PHASE1/PHASE2

8 participants

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-10-16

Completion:

2020-11-24

Conditions

• Metastatic Hepatocellular Carcinoma
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage IIIA Hepatocellular Carcinoma AJCC v8
• Stage IIIB Hepatocellular Carcinoma AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IVA Hepatocellular Carcinoma AJCC v8
• Stage IVB Hepatocellular Carcinoma AJCC v8
• Unresectable Hepatocellular Carcinoma

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT03671213 | COMPLETED | NA

81 participants

Calypso Knee System Clinical Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-09-19

Completion:

2022-01-17

Conditions

• Osteoarthritis, Knee

Interventions

• DEVICE

Results Available

NCT03576105 | COMPLETED | NA

34 participants

Evaluation of Photodynamic Therapy in Pericoronitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2019-12-01

Completion:

2024-04-20

Conditions

• Pericoronitis

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT03538665 | RECRUITING

1700 participants

The DETECT Study: Discovery and Evaluation of Testing for Endometrial and Ovarian Cancer in Tampons

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2019-07-01

Completion:

2027-08-31

Conditions

• Endometrial Cancer
• Endometrial Cancer Precursors
• Ovarian Cancer
• Complex Atypical Endometrial Hyperplasia

No Results Yet

NCT03526835 | RECRUITING | PHASE1/PHASE2

560 participants

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-05-02

Completion:

2028-05-31

Conditions

• Advanced/Metastatic Solid Tumors
• Colorectal Cancer
• Gastric Cancer
• Gastroesophageal-junction Cancer
• NSCLC
• HNSCC
• Head and Neck Squamous Cell Carcinoma
• Esophageal Cancer

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT03520751 | WITHDRAWN | PHASE1/PHASE2

0 participants

Phase I/IIa Trial of scAAV1.tMCK.NTF3 for Treatment of CMT1A

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2027-04-30

Completion:

2029-04-30

Conditions

• Charcot-Marie-Tooth Neuropathy Type 1A

Interventions

• DRUG

No Results Yet

NCT03511118 | RECRUITING

1600 participants

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2018-10-04

Completion:

2027-07-23

Conditions

• Lactating Women on Select DOI
• Breastfed Infants of Mothers on Select DOI

Interventions

• DRUG

No Results Yet

NCT03507257 | ACTIVE_NOT_RECRUITING

850 participants

Longitudinal Early-onset Alzheimer's Disease Study Protocol

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2018-04-30

Completion:

2027-01-01

Conditions

• Early Onset Alzheimer Disease
• Alzheimer Disease
• Mild Cognitive Impairment

Interventions

• DRUG

No Results Yet

NCT03487445 | COMPLETED | PHASE2

48 participants

A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Heart Attack

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-07-10

Completion:

2018-11-10

Conditions

• Acute Myocardial Infarction

Interventions

• DRUG

Results Available

NCT03425643 | ACTIVE_NOT_RECRUITING | PHASE3

797 participants

Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-04-24

Completion:

2023-07-10

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT03390673 | COMPLETED | PHASE1

119 participants

To Demonstrate Equivalent Pharmacokinetic Properties of HD204 and Bevacizumab (Avastin®) in Healthy Male Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-09-19

Completion:

2019-03-13

Conditions

• Healthy Volunteers

Interventions

• DRUG

Results Available

NCT03384966 | COMPLETED | PHASE2

346 participants

A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-01-24

Completion:

2018-08-18

Conditions

• Stable Coronary Artery Disease

Interventions

• DRUG

Results Available

NCT03309033 | ACTIVE_NOT_RECRUITING

946 participants

Extended Follow-up of Women Who Received One, Two, and Three Doses of the HPV Vaccine in the Costa Rica Vaccine Trial (CVT), ESCUDDO-CVT Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2018-07-02

Completion:

2026-03-05

Conditions

• Human Papillomavirus Infection
• Human Papillomavirus-Related Malignant Neoplasm

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT03304080 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

44 participants

Anastrozole, Palbociclib, Trastuzumab and Pertuzumab in HR-positive, HER2-positive Metastatic Breast

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2017-12-20

Completion:

2027-07-31

Conditions

• Breast Neoplasms
• Breast Diseases

Interventions

• DRUG

No Results Yet

NCT03264131 | COMPLETED | PHASE2

16 participants

BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-10-11

Completion:

2023-12-15

Conditions

• Lymphoma
• Adult T-Cell Leukemia/Lymphoma
• Lymphatic Diseases

Interventions

• DRUG

Results Available

NCT03246347 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2017-08-23

Completion:

2022-09-01

Conditions

• Prostate Cancer
• Prostate Adenocarcinoma

Interventions

• DRUG

Results Available

NCT03234478 | COMPLETED

150 participants

Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2017-07-01

Completion:

2024-06-30

Conditions

• Parkinson
• Parkinson Disease
• Genetic Predisposition
• GBA Gene Mutation
• Cognitive Decline

Results Available

NCT03190538 | RECRUITING

400 participants

Nonalcoholic Steatohepatitis in Chinese Children

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2017-05-01

Completion:

2027-05-31

Conditions

• Non-Alcoholic Fatty Liver Disease

Interventions

• OTHER

No Results Yet

NCT03151473 | RECRUITING

20000 participants

Longitudinal Observational Study Of Chinese With NAFLD/NASH

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2017-05-08

Completion:

2027-05-31

Conditions

• Non-Alcoholic Fatty Liver Disease (NAFLD)
• Non-Alcoholic Steatohepatitis (NASH)

No Results Yet

NCT03105518 | ACTIVE_NOT_RECRUITING | PHASE4

100 participants

Predictors of Postoperative Pain Following Oocyte Retrieval for Assisted Reproduction

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2011-03-01

Completion:

2027-06-30

Conditions

• Oocyte Retrieval
• Postoperative Pain

Interventions

• DRUG

Results Available

NCT03075696 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

940 participants

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2017-02-21

Completion:

2029-03-30

Conditions

• Non-Hodgkin's Lymphoma

Interventions

• DRUG

No Results Yet

NCT03031821 | TERMINATED | PHASE3

166 participants

Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-07-12

Completion:

2023-11-24

Conditions

• Prostate Cancer
• Metabolic Syndrome

Interventions

• DRUG

No Results Yet

NCT03005418 | COMPLETED | PHASE2/PHASE3

72 participants

Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2018-09-01

Completion:

2023-09-19

Conditions

• Trauma
• Vascular System Injury

Interventions

• BIOLOGICAL

Results Available

NCT02863757 | RECRUITING

1500 participants

Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-29

Start Date:

2016-08-01

Completion:

2026-12-31

Conditions

• Chronic Hepatitis B
• Nonalcoholic Fatty Liver Disease

No Results Yet

NCT02691923 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2016-03-31

Completion:

2027-12-31

Conditions

• Brain Cancer

Interventions

• DRUG

No Results Yet

NCT02616302 | COMPLETED | PHASE2

71 participants

A Study to Check the Safety of Dexlansoprazole and Learn if it Can Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children 2 to 11 Years Old

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2023-02-20

Completion:

2026-07-21

Conditions

• Gastroesophageal Reflux Disease (GERD)

Interventions

• DRUG

No Results Yet

NCT02514226 | COMPLETED | NA

30 participants

Evaluation of Periodontal Treatment in Patients With Bronchiectasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2016-08-31

Completion:

2021-07-31

Conditions

• Bronchiectasis
• Periodontal Disease

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT02486718 | ACTIVE_NOT_RECRUITING | PHASE3

1280 participants

Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2015-10-31

Completion:

2024-01-26

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT02482493 | SUSPENDED | NA

88 participants

All Polyethylene Versus Metal Backed Tibial Components in Knee Replacement

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-29

Start Date:

2017-01-31

Completion:

2027-07-31

Conditions

• Osteoarthritis, Knee

Interventions

• DEVICE

No Results Yet