Clinical Trials

NCT03911388 | RECRUITING | PHASE1

24 participants

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-09-12
Completion:: 2026-09-01

Conditions

Astrocytoma
Neoplasms
Neoplasms, Brain
Glioblastoma Multiforme
Glioblastoma of Cerebellum
Astrocytoma, Cerebellar
Neuroectodermal Tumors
Neuroectodermal Tumors, Primitive
Cerebellar PNET, Childhood
Cerebellar Neoplasms
Cerebellar Neoplasms, Primary
Cerebellar Neoplasm, Malignant
Cerebellar Neoplasm Malignant Primary
Neoplasm Metastases
Neoplasm Malignant
Neoplasms, Neuroepithelial
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Central Nervous System Neoplasms, Primary
Central Nervous System Neoplasms, Malignant
Nervous System Neoplasms
Neoplasms by Site
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Medulloblastoma Recurrent
HSV
Virus
Pediatric Brain Tumor
Nervous System Cancer
Primitive Neuroectodermal Tumor (PNET) of Cerebellum

Interventions

BIOLOGICAL

No Results Yet

NCT03899155 | RECRUITING | PHASE2

1500 participants

Pan Tumor Rollover Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-08-09
Completion:: 2029-08-25

Conditions

Cancer

Interventions

DRUG

No Results Yet

NCT03880461 | COMPLETED | NA

1335 participants

A Mobile Health Intervention to Achieve Appropriate Gestational Weight Gain in Overweight/Obese Women

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2021-01-21
Completion:: 2024-03-28

Conditions

Gestational Weight Gain

Interventions

BEHAVIORAL

Results Available

NCT03878459 | ACTIVE_NOT_RECRUITING | PHASE4

120 participants

Dapagliflozin Plus Pioglitazone in T1DM

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-08-08
Completion:: 2026-03-15

Conditions

Type 1 Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT03868670 | ACTIVE_NOT_RECRUITING | NA

6 participants

Responsive Neurostimulation For Loss Of Control Eating

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-04-10
Completion:: 2028-01-01

Conditions

Loss of Control Eating
Obesity, Morbid

Interventions

DEVICE

No Results Yet

NCT03855917 | RECRUITING | PHASE4

30 participants

Strategic Treatment Reduction in Very Early Liver Disease With 4 Weeks Sofosbuvir Plus Glecepravir-pibrentasvir

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2020-02-11
Completion:: 2029-07-31

Conditions

Hepatitis C

Interventions

DRUG

No Results Yet

NCT03838978 | COMPLETED | NA

81 participants

Calypso Knee System Clinical Study, OUS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-02-08
Completion:: 2022-01-17

Conditions

Osteoarthritis, Knee

Interventions

DEVICE

Results Available

NCT03785249 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

731 participants

Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-01-15
Completion:: 2026-06-23

Conditions

Advanced Cancer
Metastatic Cancer
Malignant Neoplastic Disease

Interventions

DRUG

No Results Yet

NCT03779854 | RECRUITING | PHASE2

68 participants

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-08-29
Completion:: 2028-12-31

Conditions

Acute Biphenotypic Leukemia
Acute Leukemia
Acute Leukemia of Ambiguous Lineage
Acute Lymphoblastic Leukemia
Acute Undifferentiated Leukemia
Allogeneic Hematopoietic Stem Cell Transplantation Recipient
Blastic Plasmacytoid Dendritic Cell Neoplasm
Blasts Under 25 Percent of Bone Marrow Nucleated Cells
Blasts Under 5 Percent of Bone Marrow Nucleated Cells
Mixed Phenotype Acute Leukemia
Myelodysplastic Syndrome With Excess Blasts-1
Myelodysplastic Syndrome/Acute Myeloid Leukemia
Burkitt Leukemia
Chronic Monocytic Leukemia
Lymphoblastic Lymphoma
Mast Cell Leukemia
Myeloproliferative Neoplasm

Interventions

RADIATION
DRUG
PROCEDURE

No Results Yet

NCT03742037 | COMPLETED | PHASE2

427 participants

Efficacy and Safety of Four Doses of Cenerimod Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-12-21
Completion:: 2021-08-31

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG

Results Available

NCT03736226 | ACTIVE_NOT_RECRUITING

2000 participants

A Post-Approval, Single-Arm Study of the SYNERGY Stent System in China

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-07-30
Completion:: 2024-08-01

Conditions

Cardiovascular Diseases

Interventions

DEVICE

No Results Yet

NCT03729778 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

100 participants

Impact of HIV-1 and Aging on Mucosal Vaccine Responses

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2017-01-18
Completion:: 2020-03-31

Conditions

HIV-1-infection
Human Immunodeficiency Virus
HIV/AIDS
HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT03716167 | RECRUITING | NA

20 participants

Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-07-27
Completion:: 2027-10-31

Conditions

Venous Leg Ulcer

Interventions

DEVICE

No Results Yet

NCT03704766 | RECRUITING | NA

442 participants

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2016-06-28
Completion:: 2026-11-30

Conditions

Joint Infection
Infection of Hip Joint (Disorder)
Infection of Shoulder Joint
Septic Arthritis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03695250 | TERMINATED | PHASE1/PHASE2

8 participants

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-10-16
Completion:: 2020-11-24

Conditions

Metastatic Hepatocellular Carcinoma
Stage III Hepatocellular Carcinoma AJCC v8
Stage IIIA Hepatocellular Carcinoma AJCC v8
Stage IIIB Hepatocellular Carcinoma AJCC v8
Stage IV Hepatocellular Carcinoma AJCC v8
Stage IVA Hepatocellular Carcinoma AJCC v8
Stage IVB Hepatocellular Carcinoma AJCC v8
Unresectable Hepatocellular Carcinoma

Interventions

DRUG
BIOLOGICAL

Results Available

NCT03671213 | COMPLETED | NA

81 participants

Calypso Knee System Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-09-19
Completion:: 2022-01-17

Conditions

Osteoarthritis, Knee

Interventions

DEVICE

Results Available

NCT03576105 | COMPLETED | NA

34 participants

Evaluation of Photodynamic Therapy in Pericoronitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-12-01
Completion:: 2024-04-20

Conditions

Pericoronitis

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT03538665 | RECRUITING

1700 participants

The DETECT Study: Discovery and Evaluation of Testing for Endometrial and Ovarian Cancer in Tampons

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2019-07-01
Completion:: 2027-08-31

Conditions

Endometrial Cancer
Endometrial Cancer Precursors
Ovarian Cancer
Complex Atypical Endometrial Hyperplasia

No Results Yet

NCT03526835 | RECRUITING | PHASE1/PHASE2

560 participants

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-05-02
Completion:: 2028-05-31

Conditions

Advanced/Metastatic Solid Tumors
Colorectal Cancer
Gastric Cancer
Gastroesophageal-junction Cancer
NSCLC
HNSCC
Head and Neck Squamous Cell Carcinoma
Esophageal Cancer

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT03520751 | WITHDRAWN | PHASE1/PHASE2

0 participants

Phase I/IIa Trial of scAAV1.tMCK.NTF3 for Treatment of CMT1A

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2027-04-30
Completion:: 2029-04-30

Conditions

Charcot-Marie-Tooth Neuropathy Type 1A

Interventions

DRUG

No Results Yet

NCT03511118 | RECRUITING

1600 participants

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-10-04
Completion:: 2027-07-23

Conditions

Lactating Women on Select DOI
Breastfed Infants of Mothers on Select DOI

Interventions

DRUG

No Results Yet

NCT03507257 | ACTIVE_NOT_RECRUITING

850 participants

Longitudinal Early-onset Alzheimer's Disease Study Protocol

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-04-30
Completion:: 2027-01-01

Conditions

Early Onset Alzheimer Disease
Alzheimer Disease
Mild Cognitive Impairment

Interventions

DRUG

No Results Yet

NCT03487445 | COMPLETED | PHASE2

48 participants

A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Heart Attack

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-07-10
Completion:: 2018-11-10

Conditions

Acute Myocardial Infarction

Interventions

DRUG

Results Available

NCT03425643 | ACTIVE_NOT_RECRUITING | PHASE3

797 participants

Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-04-24
Completion:: 2023-07-10

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG
BIOLOGICAL

Results Available

NCT03390673 | COMPLETED | PHASE1

119 participants

To Demonstrate Equivalent Pharmacokinetic Properties of HD204 and Bevacizumab (Avastin®) in Healthy Male Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-09-19
Completion:: 2019-03-13

Conditions

Healthy Volunteers

Interventions

DRUG

Results Available

NCT03384966 | COMPLETED | PHASE2

346 participants

A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-01-24
Completion:: 2018-08-18

Conditions

Stable Coronary Artery Disease

Interventions

DRUG

Results Available

NCT03309033 | ACTIVE_NOT_RECRUITING

946 participants

Extended Follow-up of Women Who Received One, Two, and Three Doses of the HPV Vaccine in the Costa Rica Vaccine Trial (CVT), ESCUDDO-CVT Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-07-02
Completion:: 2026-03-05

Conditions

Human Papillomavirus Infection
Human Papillomavirus-Related Malignant Neoplasm

Interventions

PROCEDURE
OTHER

No Results Yet

NCT03304080 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

44 participants

Anastrozole, Palbociclib, Trastuzumab and Pertuzumab in HR-positive, HER2-positive Metastatic Breast

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2017-12-20
Completion:: 2027-07-31

Conditions

Breast Neoplasms
Breast Diseases

Interventions

DRUG

No Results Yet

NCT03264131 | COMPLETED | PHASE2

16 participants

BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-10-11
Completion:: 2023-12-15

Conditions

Lymphoma
Adult T-Cell Leukemia/Lymphoma
Lymphatic Diseases

Interventions

DRUG

Results Available

NCT03246347 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2017-08-23
Completion:: 2022-09-01

Conditions

Prostate Cancer
Prostate Adenocarcinoma

Interventions

DRUG

Results Available

NCT03234478 | COMPLETED

150 participants

Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2017-07-01
Completion:: 2024-06-30

Conditions

Parkinson
Parkinson Disease
Genetic Predisposition
GBA Gene Mutation
Cognitive Decline

Results Available

NCT03190538 | RECRUITING

400 participants

Nonalcoholic Steatohepatitis in Chinese Children

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2017-05-01
Completion:: 2027-05-31

Conditions

Non-Alcoholic Fatty Liver Disease

Interventions

OTHER

No Results Yet

NCT03151473 | RECRUITING

20000 participants

Longitudinal Observational Study Of Chinese With NAFLD/NASH

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2017-05-08
Completion:: 2027-05-31

Conditions

Non-Alcoholic Fatty Liver Disease (NAFLD)
Non-Alcoholic Steatohepatitis (NASH)

No Results Yet

NCT03105518 | ACTIVE_NOT_RECRUITING | PHASE4

100 participants

Predictors of Postoperative Pain Following Oocyte Retrieval for Assisted Reproduction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2011-03-01
Completion:: 2027-06-30

Conditions

Oocyte Retrieval
Postoperative Pain

Interventions

DRUG

Results Available

NCT03075696 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

940 participants

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2017-02-21
Completion:: 2029-03-30

Conditions

Non-Hodgkin's Lymphoma

Interventions

DRUG

No Results Yet

NCT03031821 | TERMINATED | PHASE3

166 participants

Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-07-12
Completion:: 2023-11-24

Conditions

Prostate Cancer
Metabolic Syndrome

Interventions

DRUG

No Results Yet

NCT03005418 | COMPLETED | PHASE2/PHASE3

72 participants

Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2018-09-01
Completion:: 2023-09-19

Conditions

Trauma
Vascular System Injury

Interventions

BIOLOGICAL

Results Available

NCT02863757 | RECRUITING

1500 participants

Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-29
Start Date:: 2016-08-01
Completion:: 2026-12-31

Conditions

Chronic Hepatitis B
Nonalcoholic Fatty Liver Disease

No Results Yet

NCT02691923 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2016-03-31
Completion:: 2027-12-31

Conditions

Brain Cancer

Interventions

DRUG

No Results Yet

NCT02616302 | COMPLETED | PHASE2

71 participants

A Study to Check the Safety of Dexlansoprazole and Learn if it Can Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children 2 to 11 Years Old

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-29
Start Date:: 2023-02-20
Completion:: 2026-07-21

Conditions

Gastroesophageal Reflux Disease (GERD)

Interventions

DRUG

No Results Yet