Clinical Trials

NCT02306161 | ACTIVE_NOT_RECRUITING | PHASE3
312 participants

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-29
Start Date:
2014-12-12
Completion:
2021-03-31
Conditions
  • Metastatic Ewing Sarcoma
  • Metastatic Malignant Neoplasm in the Bone
  • Metastatic Malignant Neoplasm in the Bone Marrow
  • Metastatic Malignant Neoplasm in the Lung
  • Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone
  • Peripheral Primitive Neuroectodermal Tumor of Soft Tissues
Interventions
  • DRUG
  • RADIATION
  • BIOLOGICAL
  • PROCEDURE
NCT02166463 | ACTIVE_NOT_RECRUITING | PHASE3
600 participants

Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-29
Start Date:
2015-03-19
Completion:
2021-12-31
Conditions
  • Ann Arbor Stage IIB Hodgkin Lymphoma
  • Ann Arbor Stage IIIB Hodgkin Lymphoma
  • Ann Arbor Stage IVA Hodgkin Lymphoma
  • Ann Arbor Stage IVB Hodgkin Lymphoma
  • Childhood Hodgkin Lymphoma
  • Classic Hodgkin Lymphoma
Interventions
  • BIOLOGICAL
  • DRUG
  • OTHER
NCT02142803 | ACTIVE_NOT_RECRUITING | PHASE1
50 participants

TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-29
Start Date:
2014-05-20
Completion:
2020-12-31
Conditions
  • Adult Glioblastoma
  • Endometrial Clear Cell Adenocarcinoma
  • Endometrial Serous Adenocarcinoma
  • Ovarian Clear Cell Cystadenocarcinoma
  • Ovarian Endometrioid Adenocarcinoma
  • Ovarian Mucinous Cystadenocarcinoma
  • Ovarian Serous Cystadenocarcinoma
  • Recurrent Fallopian Tube Carcinoma
  • Recurrent Malignant Uterine Corpus Neoplasm
  • Recurrent Ovarian Carcinoma
  • Recurrent Primary Peritoneal Carcinoma
  • Solid Neoplasm
  • Stage IIIA Fallopian Tube Cancer AJCC v7
  • Stage IIIA Ovarian Cancer AJCC v6 and v7
  • Stage IIIA Primary Peritoneal Cancer AJCC v7
  • Stage IIIB Fallopian Tube Cancer AJCC v7
  • Stage IIIB Ovarian Cancer AJCC v6 and v7
  • Stage IIIB Primary Peritoneal Cancer AJCC v7
  • Stage IIIC Fallopian Tube Cancer AJCC v7
  • Stage IIIC Ovarian Cancer AJCC v6 and v7
  • Stage IIIC Primary Peritoneal Cancer AJCC v7
  • Stage IV Fallopian Tube Cancer AJCC v6 and v7
  • Stage IV Ovarian Cancer AJCC v6 and v7
  • Stage IV Primary Peritoneal Cancer AJCC v7
Interventions
  • BIOLOGICAL
  • OTHER
  • DRUG
NCT02112916 | ACTIVE_NOT_RECRUITING | PHASE3
847 participants

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-29
Start Date:
2014-10-04
Completion:
2020-03-31
Conditions
  • Adult T Acute Lymphoblastic Leukemia
  • Ann Arbor Stage II Adult Lymphoblastic Lymphoma
  • Ann Arbor Stage II Childhood Lymphoblastic Lymphoma
  • Ann Arbor Stage III Adult Lymphoblastic Lymphoma
  • Ann Arbor Stage III Childhood Lymphoblastic Lymphoma
  • Ann Arbor Stage IV Adult Lymphoblastic Lymphoma
  • Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma
  • Childhood T Acute Lymphoblastic Leukemia
Interventions
  • DRUG
  • RADIATION
NCT01468896 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
23 participants

Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That is Recurrent, Metastatic, or Cannot Be Removed by Surgery

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-29
Start Date:
2011-10-26
Completion:
2015-09-29
Conditions
  • Metastatic Head and Neck Squamous Cell Carcinoma
  • Recurrent Head and Neck Squamous Cell Carcinoma
  • Unresectable Head and Neck Squamous Cell Carcinoma
Interventions
  • BIOLOGICAL
  • OTHER
NCT00972478 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
83 participants

Vorinostat, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-29
Start Date:
2010-11-15
Completion:
2015-12-30
Conditions
  • Ann Arbor Stage II Non-Hodgkin Lymphoma
  • Ann Arbor Stage III Non-Hodgkin Lymphoma
  • Ann Arbor Stage IV Non-Hodgkin Lymphoma
Interventions
  • DRUG
  • OTHER
  • BIOLOGICAL
NCT00792948 | ACTIVE_NOT_RECRUITING | PHASE2
97 participants

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-29
Start Date:
2009-09-01
Completion:
2016-06-01
Conditions
  • Acute Lymphoblastic Leukemia
  • Adult B Acute Lymphoblastic Leukemia
  • Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
  • Adult L1 Acute Lymphoblastic Leukemia
  • Adult L2 Acute Lymphoblastic Leukemia
  • Adult T Acute Lymphoblastic Leukemia
  • Recurrent Adult Acute Lymphoblastic Leukemia
Interventions
  • DRUG
  • PROCEDURE
  • BIOLOGICAL
  • OTHER
  • RADIATION
NCT00569127 | ACTIVE_NOT_RECRUITING | PHASE3
427 participants

Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-29
Start Date:
2007-12-01
Completion:
2015-01-01
Conditions
  • Colorectal Neuroendocrine Tumor G1
  • Gastric Neuroendocrine Tumor G1
  • Neuroendocrine Neoplasm
  • Neuroendocrine Tumor
  • Neuroendocrine Tumor G2
Interventions
  • BIOLOGICAL
  • OTHER
  • DRUG
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