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Clinical Trials

NCT03917043 | RECRUITING | PHASE1
165 participants

APG-2449 in Patients With Advanced Solid Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-23
Start Date:
2019-05-27
Completion:
2027-12-31
Conditions
  • Advanced Solid Cancer
  • Non Small Cell Lung Cancer
  • Esophageal Cancer
  • Ovarian Cancer
  • Malignant Pleural Mesothelioma
Interventions
  • DRUG
No Results Yet
NCT03851575 | ACTIVE_NOT_RECRUITING | NA
508 participants

Accelerated Treatment of Endocarditis

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-23
Start Date:
2019-01-17
Completion:
2026-04-28
Conditions
  • Infectious Endocarditis
Interventions
  • OTHER
No Results Yet
NCT03586661 | COMPLETED | PHASE1
31 participants

Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-23
Start Date:
2019-04-29
Completion:
2026-06-16
Conditions
  • Deleterious BRCA1 Gene Mutation
  • Deleterious BRCA2 Gene Mutation
  • Endometrial Adenocarcinoma
  • High Grade Ovarian Serous Adenocarcinoma
  • Platinum-Resistant Ovarian Carcinoma
  • Primary Peritoneal High Grade Serous Adenocarcinoma
  • Progressive Disease
  • Recurrent Endometrial Carcinoma
  • Recurrent Fallopian Tube Carcinoma
  • Recurrent Ovarian Carcinoma
  • Recurrent Primary Peritoneal Carcinoma
Interventions
  • DRUG
No Results Yet
NCT03433274 | ACTIVE_NOT_RECRUITING | NA
103 participants

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-23
Start Date:
2018-06-15
Completion:
2024-04-29
Conditions
  • Mitral Regurgitation
  • Mitral Insufficiency
  • Mitral Valve Insufficiency
  • Cardiovascular Diseases
  • Valve Disease, Heart
  • Heart Valve Diseases
  • Functional Mitral Regurgitation
  • Degenerative Mitral Valve Disease
Interventions
  • DEVICE
Results Available
NCT03333616 | ACTIVE_NOT_RECRUITING | PHASE2
100 participants

Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-23
Start Date:
2017-12-28
Completion:
2026-12-30
Conditions
  • Genitourinary Cancer
  • Adrenocortical Carcinoma
  • Non-urothelial Bladder
  • Non-urothelial Upper Tract
  • Penile Cancer
  • Non-adenocarcinoma Prostate Cancer
  • Refractory Germ-cell
  • High Grade Neuroendocrine Carcinoma/Small Cell Carcinoma
Interventions
  • DRUG
No Results Yet
NCT03247712 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
22 participants

Neoadjuvant Immunoradiotherapy in Head & Neck Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-23
Start Date:
2018-01-15
Completion:
2020-02-13
Conditions
  • Head and Neck Cancer
  • Head and Neck Squamous Cell Carcinoma
Interventions
  • DRUG
  • PROCEDURE
  • RADIATION
No Results Yet
NCT02726061 | RECRUITING | NA
500 participants

Internet Based Psychological Support

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-23
Start Date:
2016-02-29
Completion:
2031-02-28
Conditions
  • Depression
  • Stress
  • Conflict Resolution
Interventions
  • BEHAVIORAL
No Results Yet
NCT01238250 | RECRUITING
100000 participants

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

Study Type:
OBSERVATIONAL
Last Updated:
2026-07-23
Start Date:
2010-10-31
Completion:
2050-10-31
Conditions
  • PACS1
  • MBD5
  • MED13L
  • 16P11.2 Deletion Syndrome
  • 16p11.2 Duplications
  • 1Q21.1 Deletion
  • 1Q21.1 Microduplication Syndrome (Disorder)
  • ACTL6B
  • ADNP
  • AHDC1
  • ANK2
  • ANKRD11
  • ARID1B
  • ASH1L
  • BCL11A
  • CHAMP1
  • CHD2
  • CHD8
  • CSNK2A1
  • CTBP1
  • CTNNB1 Gene Mutation
  • CUL3
  • DDX3X
  • DNMT3A
  • DSCAM
  • DYRK1A
  • FOXP1
  • GRIN2A
  • GRIN2B
  • HIVEP2-Related Intellectual Disability
  • HNRNPH2
  • KATNAL2
  • KDM5B
  • KDM6B
  • KMT2C Gene Mutation
  • KMT2E
  • KMT5B
  • PPP2R5D-Related Intellectual Disability
  • PTCHD1
  • REST
  • SCN2A Encephalopathy
  • SETBP1 Gene Mutation
  • SETD5
  • SMARCA4 Gene Mutation
  • SMARCC2
  • STXBP1 Encephalopathy With Epilepsy
  • SYNGAP1-Related Intellectual Disability
  • TBR1
  • ARHGEF9
  • HNRNPU
  • PPP3CA
  • PPP2R1A
  • SLC6A1
  • 2p16.3 Deletions
  • 5q35 Deletions
  • 5q35 Duplications
  • 7q11.23 Duplications
  • 15Q13.3 Deletion Syndrome
  • 16p11.2 Triplications
  • 16P12.2 Microdeletion
  • 16P13.11 Microdeletion Syndrome (Disorder)
  • 17Q12 Microdeletion Syndrome (Disorder)
  • 17Q12 Duplication Syndrome
  • 17Q21.31 Deletion Syndrome
  • 17q21.3 Duplications
  • ACTB
  • ADSL
  • AFF2
  • ALDH5A1
  • ANK3
  • ARX
  • ATRX Gene Mutation
  • AUTS2 Syndrome
  • BCKDK
  • BRSK2
  • CACNA1C
  • CAPRIN1
  • CASK
  • CASZ1
  • CHD3
  • CIC
  • CNOT3
  • CREBBP Gene Mutation
  • CSDE1
  • CTCF
  • DEAF1
  • DHCR7
  • DLG4
  • EBF3
  • EHMT1
  • EP300 Gene Mutation
  • GIGYF1
  • GRIN1
  • GRIN2D
  • IQSEC2-Related Syndromic Intellectual Disability
  • IRF2BPL
  • KANSL1
  • KCNB1
  • KDM3B
  • NEXMIF
  • KMT2A
  • MBOAT7
  • MEIS2
  • MYT1L
  • NAA15
  • NBEA
  • NCKAP1
  • NIPBL
  • NLGN2
  • NLGN3
  • NLGN4X
  • NR4A2
  • NRXN1
  • NRXN2
  • NSD1 Gene Mutation
  • PHF21A
  • PHF3
  • PHIP
  • PSMD12
  • RELN
  • RERE
  • RFX3
  • RIMS1
  • RORB
  • SCN1A
  • SETD2 Gene Mutation
  • SHANK2
  • SIN3A
  • SLC9A6
  • SON
  • SOX5
  • SPAST
  • SRCAP
  • TAOK1
  • TANC2
  • TCF20
  • TLK2
  • TRIO
  • TRIP12
  • UPF3B
  • USP9X
  • VPS13B
  • WAC
  • WDFY3
  • ZBTB20
  • ZNF292
  • ZNF462
  • 2Q37 Deletion Syndrome
  • 9q34 Duplications
  • 15q15 Deletions
  • 15Q24 Deletion
  • NR3C2
  • SYNCRIP
  • 2q37.3 Deletion
  • 6q16 Deletion
  • 15q11.2 BP1-BP2 Deletion
  • 16p13.3 Deletion
  • 17Q11.2 Microduplication Syndrome (Disorder)
  • 17p13.3
  • Xq28 Duplication
  • CLCN4
  • CSNK2B
  • DYNC1H1
  • EIF3F
  • GNB1
  • MED13
  • MEF2C
  • RALGAPB
  • SCN1B
  • YY1
  • Xp11.22 Duplication
  • PACS2
  • MAOA
  • MAOB
  • HNRNPC
  • HNRNPD
  • HNRNPK
  • HNRNPR
  • HNRNPUL2
  • 5P Deletion Syndrome
  • TCF7L2 Gene Mutation
  • HECW2
  • PPM1D
  • RNU4-2
  • SNAP25
  • FOXP2
  • ITSN1
No Results Yet
NCT07721220 | RECRUITING | NA
45 participants

Acute Effects of Neurodynamics on Strength and Endurance in Athletes

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-22
Start Date:
2026-06-15
Completion:
2026-07-31
Conditions
  • Sciatic Leg Pain
  • Hamstring Muscle Tightness
  • Hamstring Muscle Strain
  • Hamstring Muscle Strength
  • Hamstring Injuries
  • Hamstring Injury Prevention
  • Hamstring Rupture
  • Sciatic Nerve Injury
  • Sciatic Radiculopathy
  • Lumbar Disc Herniation With Radiculopathy
  • Lumbar Disc Herniation
Interventions
  • OTHER
  • DEVICE
No Results Yet
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