Clinical Trials

NCT04504526 | RECRUITING | EARLY_PHASE1

50 participants

Value of Chemokine Receptor CXCR4 Imaging for Diagnosis and Prognostic Evaluation in Lymphoproliferative Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2020-08-07

Completion:

2027-12-31

Conditions

• Lymphoma
• Multiple Myeloma
• Leukemia

Interventions

• DRUG

No Results Yet

NCT04499365 | RECRUITING | EARLY_PHASE1

500 participants

68Ga-FAPI PET/CT in Patients With Various Types of Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2020-08-15

Completion:

2027-12-30

Conditions

• Tumor
• Positron-Emission Tomography
• Metastasis

Interventions

• DRUG
• DIAGNOSTIC_TEST

No Results Yet

NCT04464980 | ACTIVE_NOT_RECRUITING | PHASE2

1516 participants

Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2021-06-08

Completion:

2026-12-31

Conditions

• Opioid Use Disorder (OUD)

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT04458974 | COMPLETED | NA

20 participants

tDCS in Post-stroke Neglect Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-11-08

Completion:

2025-11-03

Conditions

• Stroke
• Neglect, Hemispatial

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT04447651 | ACTIVE_NOT_RECRUITING

6 participants

Patient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-21

Start Date:

2020-09-17

Completion:

2023-05-15

Conditions

• Metastatic Solid Tumor
• SF3B1 Gene Mutation
• Spliceosome Mutation
• U2AF1 Gene Mutation
• SRSF2 Gene Mutation

Interventions

• OTHER

No Results Yet

NCT04409639 | ACTIVE_NOT_RECRUITING | PHASE2

14 participants

Cobimetinib in Newly Diagnosed or HMA-treated CMML Patients With RAS Pathway Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2021-01-12

Completion:

2026-01-02

Conditions

• Chronic Myelomonocytic Leukemia (CMML)

Interventions

• DRUG

Results Available

NCT04394338 | COMPLETED | NA

60 participants

The Plastic Covering Method for Self-gripping Mesh Placement in Laparoscopic Inguinal Hernia Repair

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2020-02-01

Completion:

2021-12-31

Conditions

• Laparoscopic Inguinal Hernia Repair

Interventions

• OTHER

No Results Yet

NCT04364503 | ENROLLING_BY_INVITATION

2000 participants

Compliant Analysis of Patient Samples and Data

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-21

Start Date:

2018-03-17

Completion:

2030-03-17

Conditions

• Pregnancy Related
• Cancer
• Infectious Disease

Interventions

• DEVICE

No Results Yet

NCT04348747 | RECRUITING | PHASE2

23 participants

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2022-12-19

Completion:

2028-05-15

Conditions

• Anatomic Stage IV Breast Cancer AJCC v8
• Metastatic Malignant Neoplasm in the Brain
• Metastatic Triple-Negative Breast Carcinoma
• Prognostic Stage IV Breast Cancer AJCC v8

Interventions

• BIOLOGICAL

No Results Yet

NCT04297683 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

1500 participants

HEALEY ALS Platform Trial - Master Protocol

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2020-06-14

Completion:

2027-07-31

Conditions

• Amyotrophic Lateral Sclerosis

Interventions

• DRUG

No Results Yet

NCT04287166 | ACTIVE_NOT_RECRUITING

100 participants

Early Remote At-risk Diagnosis for Cerebral Palsy in Follow-up Clinics for High-risk Infants

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-21

Start Date:

2020-08-03

Completion:

2027-06-01

Conditions

• Cerebral Palsy

No Results Yet

NCT04254133 | ENROLLING_BY_INVITATION

1360 participants

Genetic Information to Inform Treatment and Screening for Prostate Cancer, GIFTS Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-21

Start Date:

2018-11-30

Completion:

2028-08-31

Conditions

• Prostate Carcinoma

Interventions

• BEHAVIORAL
• PROCEDURE
• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT04221477 | ACTIVE_NOT_RECRUITING | PHASE3

271 participants

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus Nephritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2020-08-10

Completion:

2024-08-15

Conditions

• Lupus Nephritis

Interventions

• DRUG

Results Available

NCT04204915 | RECRUITING | NA

2104 participants

The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2020-03-10

Completion:

2031-04-01

Conditions

• Aortic Stenosis

Interventions

• PROCEDURE

No Results Yet

NCT04199000 | RECRUITING

500 participants

Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-21

Start Date:

2019-10-08

Completion:

2030-07-31

Conditions

• Congenital Disorders of Glycosylation

No Results Yet

NCT04174352 | RECRUITING | EARLY_PHASE1

12 participants

FES Imaging to Optimize Tamoxifen for Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2020-10-20

Completion:

2026-12-31

Conditions

• ERα+ Breast Cancer
• ESR1 Gene Mutation

Interventions

• DRUG
• DIAGNOSTIC_TEST

No Results Yet

NCT04174079 | RECRUITING | NA

232 participants

Study on Adjuvant Chemotherapy After Total Two-field Lymph Node Dissection of Thoracic Esophageal Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-12-11

Completion:

2029-05-31

Conditions

• Thoracic Esophageal Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT04165824 | COMPLETED | PHASE3

185 participants

Safety Study of Oral Edaravone Administered in Subjects With ALS

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-11-18

Completion:

2021-10-07

Conditions

• ALS

Interventions

• DRUG

Results Available

NCT04155190 | TERMINATED | PHASE2

50 participants

A Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-12-20

Completion:

2021-04-23

Conditions

• Recurrent Basal Cell Carcinoma

Interventions

• DRUG

Results Available

NCT04141202 | RECRUITING

200 participants

Structured Physical Exercise in Short-term Inpatient Treatment of Substance Use Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-21

Start Date:

2020-02-25

Completion:

2035-12-30

Conditions

• Substance-Related Disorders
• Drug Abuse
• Drug Dependence

No Results Yet

NCT04054050 | COMPLETED | NA

27 participants

Bright Light Therapy for Sleep Disturbance in People With Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2021-02-22

Completion:

2025-09-30

Conditions

• Multiple Sclerosis

Interventions

• OTHER

No Results Yet

NCT04022213 | ACTIVE_NOT_RECRUITING | PHASE2

31 participants

A Study of the Drug I131-Omburtamab in People With Desmoplastic Small Round Cell Tumors and Other Solid Tumors in the Peritoneum

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-07-15

Completion:

2027-07-31

Conditions

• Desmoplastic Small Round Cell Tumor
• Peritoneal Cancer
• Peritoneal Carcinoma

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04011722 | ACTIVE_NOT_RECRUITING | NA

333 participants

Portico Next Generation Approval Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-09-17

Completion:

2023-01-12

Conditions

• Symptomatic Severe Aortic Stenosis

Interventions

• DEVICE

Results Available

NCT03958747 | COMPLETED | NA

20 participants

Ultrasound for the Detection of Oxaliplatin-Induced Peripheral Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-12-17

Completion:

2025-11-26

Conditions

• Gastrointestinal Cancer
• Colorectal Cancer

Interventions

• DIAGNOSTIC_TEST
• PROCEDURE
• OTHER

No Results Yet

NCT03949855 | RECRUITING | PHASE2

58 participants

Belimumab With Rituximab for Primary Membranous Nephropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2020-03-06

Completion:

2029-03-01

Conditions

• Membranous Nephropathy
• Nephrotic Syndrome

Interventions

• DRUG

No Results Yet

NCT03887273 | RECRUITING | PHASE1/PHASE2

9 participants

Study to Investigate the Safety of the Transplantation of Human Glial Restricted Progenitor Cells Into Subjects With Transverse Myelitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2022-09-20

Completion:

2027-07-31

Conditions

• Transverse Myelitis

Interventions

• BIOLOGICAL

No Results Yet

NCT03873259 | RECRUITING | NA

40 participants

Intraoperative Assessment of of Burst Wave Lithotripsy (BWL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-08-08

Completion:

2027-12-31

Conditions

• Renal Calculi
• Ureteral Calculi

Interventions

• DEVICE

No Results Yet

NCT03816358 | ACTIVE_NOT_RECRUITING | PHASE1

74 participants

Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-12-09

Completion:

2027-01-31

Conditions

• Pancreatic Adenocarcinoma
• Stage II Pancreatic Cancer AJCC v8
• Stage III Pancreatic Cancer AJCC v8
• Stage IV Pancreatic Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT03765879 | ACTIVE_NOT_RECRUITING | NA

80 participants

Brain Mechanisms of Video-Guided Acupuncture Imagery Treatment on Chronic Low Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2019-02-14

Completion:

2024-07-27

Conditions

• Chronic Pain

Interventions

• OTHER

No Results Yet

NCT03677427 | COMPLETED | NA

488 participants

Comparing 5 and 15 Fractions for Whole Breast Irradiation After Breast Conserving Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2017-10-16

Completion:

2023-06-23

Conditions

• Breast Cancer

Interventions

• RADIATION

No Results Yet

NCT03655132 | COMPLETED | NA

42 participants

Developing an Online Therapeutic Intervention for Chronic Pain in Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2022-03-17

Completion:

2023-05-30

Conditions

• Chronic Pain

Interventions

• BEHAVIORAL

Results Available

NCT03632044 | ACTIVE_NOT_RECRUITING | PHASE4

40 participants

Evaluation of Trigeminal Nerve Blockade

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2018-11-20

Completion:

2027-05-31

Conditions

• Mouth Abnormalities
• Cleft Palate
• Birth Defect

Interventions

• DRUG
• OTHER

No Results Yet

NCT03631225 | COMPLETED

1500 participants

The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-21

Start Date:

2019-06-25

Completion:

2026-07-01

Conditions

• Rheumatoid Arthritis (RA)

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03495011 | ACTIVE_NOT_RECRUITING

122 participants

MRI Characterization of Mammographically Detected DCIS

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-21

Start Date:

2018-04-20

Completion:

2023-04-30

Conditions

• Breast Cancer, Stage 0

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT03445000 | TERMINATED | PHASE2

14 participants

ALEctinib for the Treatment of Pretreated RET-rearranged Advanced Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2018-11-06

Completion:

2021-03-31

Conditions

• Non-small Cell Lung Cancer
• Non-small Cell Lung Cancer Metastatic
• Non-small Cell Lung Cancer Recurrent

Interventions

• DRUG

Results Available

NCT03400826 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Effects of Simvastatin on Uterine Leiomyoma Size

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2018-08-20

Completion:

2026-07-31

Conditions

• Fibroid Uterus
• Fibroid Tumor
• Leiomyoma
• Fibromyoma
• Leiomyoma, Uterine

Interventions

• DRUG

No Results Yet

NCT03369210 | COMPLETED | PHASE3

4456 participants

Liberal Transfusion Strategy in Elderly Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2018-01-09

Completion:

2025-06-30

Conditions

• Transfusion-dependent Anemia
• Surgery
• Anemia

Interventions

• DRUG

No Results Yet

NCT03255577 | ACTIVE_NOT_RECRUITING | NA

162 participants

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy For Locally Advanced Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2017-08-17

Completion:

2027-06-15

Conditions

• Breast Cancer
• Locally Advanced Breast Cancer

Interventions

• PROCEDURE

No Results Yet

NCT03228420 | COMPLETED | NA

430 participants

Comparison of 10 kHz SCS Combined With CMM to CMM Alone in the Treatment of Neuropathic Limb Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2017-07-20

Completion:

2020-05-01

Conditions

• Painful Diabetic Neuropathy

Interventions

• DEVICE
• OTHER

Results Available

NCT03121066 | NOT_YET_RECRUITING | NA

45 participants

Transcranial Magnetic Stimulation for Alzheimer's Disease Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-21

Start Date:

2027-11-30

Completion:

2027-11-30

Conditions

• Alzheimer Disease

Interventions

• DEVICE

No Results Yet