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The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis

NCT03631225 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1500

Last updated 2026-07-21

No results posted yet for this study

Summary

The goal of treating patients diagnosed with rheumatoid arthritis (RA) is to achieve remission or low disease activity and thereby prevent joint damage, loss of physical function, and disability. Optimal management requires regular assessment of disease activity, with treatment changes made as needed for optimal efficacy. Vectra is a blood serum test that looks at 12 biomarkers and produces a score on a scale of 1 to 100. The Vectra score has been shown to be the strongest predictor of risk for progression of disease. There is opportunity to gain more information about the utility of Vectra in a real-world clinical setting. This study will, therefore, evaluate the utility of Vectra for guiding treatment decisions and improving RA-related outcomes in comparison with usual care, which will not include Vectra testing. This study will enable a direct evaluation of the clinical benefit associated with using Vectra to guide treatment decisions in patients with RA.

Conditions

  • Rheumatoid Arthritis (RA)

Interventions

DIAGNOSTIC_TEST

Vectra

Each arm will have the Vectra test however, scores will not be provided for the Usual Care Arm until end of study (12 month time point)

Sponsors & Collaborators

  • Laboratory Corporation of America

    collaborator INDUSTRY

  • Sequenom, Inc.

    lead INDUSTRY

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-06-25
Primary Completion
2026-07-01
Completion
2026-07-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03631225 on ClinicalTrials.gov