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Clinical Trials

NCT03862157 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
40 participants

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-16
Start Date:
2019-02-27
Completion:
2027-01-31
Conditions
  • Acute Myeloid Leukemia
  • Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative
  • Chronic Eosinophilic Leukemia, Not Otherwise Specified
  • Chronic Myelomonocytic Leukemia
  • Chronic Neutrophilic Leukemia
  • Essential Thrombocythemia
  • Myelodysplastic Syndrome
  • Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis
  • Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable
  • Myeloid Neoplasm
  • Myeloproliferative Neoplasm
  • Myeloproliferative Neoplasm, Unclassifiable
  • Overt Primary Myelofibrosis
  • Polycythemia Vera
  • Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase
  • Prefibrotic/Early Primary Myelofibrosis
Interventions
  • DRUG
No Results Yet
NCT03744793 | ACTIVE_NOT_RECRUITING | PHASE2
18 participants

Pemetrexed and Avelumab in Treating Patients With MTAP-Deficient Metastatic Urothelial Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-16
Start Date:
2019-04-11
Completion:
2027-01-31
Conditions
  • Infiltrating Bladder Urothelial Carcinoma Sarcomatoid Variant
  • Infiltrating Bladder Urothelial Carcinoma With Glandular Differentiation
  • Infiltrating Bladder Urothelial Carcinoma With Squamous Differentiation
  • Infiltrating Bladder Urothelial Carcinoma, Micropapillary Variant
  • Infiltrating Bladder Urothelial Carcinoma, Plasmacytoid Variant
  • Metastatic Urothelial Carcinoma
  • MTAP Negative
Interventions
  • DRUG
No Results Yet
NCT03653507 | ACTIVE_NOT_RECRUITING | PHASE3
507 participants

A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-16
Start Date:
2018-11-28
Completion:
2022-10-25
Conditions
  • Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer
  • Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
  • Metastatic Gastric Adenocarcinoma or Cancer
  • Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
Interventions
  • DRUG
Results Available
NCT03599752 | ACTIVE_NOT_RECRUITING | PHASE2
40 participants

Chemotherapy and/or Metastasectomy in Treating Patients With Metastatic Colorectal Adenocarcinoma With Lung Metastases

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-16
Start Date:
2018-07-02
Completion:
2030-01-31
Conditions
  • Colorectal Adenocarcinoma
  • Colorectal Carcinoma Metastatic in the Lung
  • Stage IV Colorectal Cancer AJCC v8
  • Stage IVA Colorectal Cancer AJCC v8
  • Stage IVB Colorectal Cancer AJCC v8
  • Stage IVC Colorectal Cancer AJCC v8
Interventions
  • DRUG
  • PROCEDURE
No Results Yet
NCT03565783 | ACTIVE_NOT_RECRUITING | PHASE2
44 participants

Cemiplimab in Treating Patients With Recurrent and Resectable Stage II-IV Head and Neck Cutaneous Squamous Cell Cancer Before Surgery

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-16
Start Date:
2018-07-03
Completion:
2027-12-31
Conditions
  • Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck
  • Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck
  • Stage II Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
  • Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
  • Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Interventions
  • BIOLOGICAL
No Results Yet
NCT03541902 | ACTIVE_NOT_RECRUITING | PHASE2
32 participants

Cabozantinib or Sunitinib Malate in Treating Participants With Metastatic Variant Histology Renal Cell Carcinoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-16
Start Date:
2018-05-15
Completion:
2027-07-31
Conditions
  • Malignant Neoplasms of Urinary Tract
  • Renal Cell Carcinoma
  • Chromophobe Renal Cell Carcinoma
  • Metastatic Renal Cell Carcinoma
  • Papillary Renal Cell Carcinoma
  • Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions
  • Sarcomatoid Renal Cell Carcinoma
  • Stage IV Renal Cell Cancer AJCC v8
  • Unclassified Renal Cell Carcinoma
Interventions
  • DRUG
No Results Yet
NCT03287492 | ACTIVE_NOT_RECRUITING | NA
207 participants

RCT of QPS vs General Information Sheet

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-16
Start Date:
2017-09-25
Completion:
2027-12-31
Conditions
  • Advanced Malignant Neoplasm
  • Caregiver
  • Physician
Interventions
  • OTHER
No Results Yet
NCT03225664 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
37 participants

Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally Advanced

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-16
Start Date:
2018-02-03
Completion:
2027-12-31
Conditions
  • Metastatic Lung Non-Small Cell Carcinoma
  • Recurrent Lung Non-Small Cell Carcinoma
  • Stage III Lung Cancer AJCC v8
  • Stage IIIA Lung Cancer AJCC v8
  • Stage IIIB Lung Cancer AJCC v8
  • Stage IIIC Lung Cancer AJCC v8
  • Stage IV Lung Cancer AJCC v8
  • Stage IVA Lung Cancer AJCC v8
  • Stage IVB Lung Cancer AJCC v8
  • Unresectable Lung Non-Small Cell Carcinoma
Interventions
  • BIOLOGICAL
  • OTHER
  • DRUG
No Results Yet
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