Clinical Trials

NCT04661150 | ACTIVE_NOT_RECRUITING | PHASE2

42 participants

A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced Resectable Gastric Cancer of Adenocarcinoma of Gastroesophageal Junction

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2021-03-12

Completion:

2023-05-08

Conditions

• Gastric Cancer
• Gastroesophageal Junction Adenocarcinoma

Interventions

• DRUG

Results Available

NCT04632238 | COMPLETED | NA

7950 participants

Coaching Performance Driven Practice Change in the Context of Value Based Purchasing Under New York Medicaid

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-07-01

Completion:

2025-06-30

Conditions

• Opioid-use Disorder
• Substance Use Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT04538755 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

20 participants

DAW2020 on OSA Endotypic Traits

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-11-15

Completion:

2025-05-15

Conditions

• Obstructive Sleep Apnea (OSA)

Interventions

• DRUG

No Results Yet

NCT04515875 | COMPLETED | NA

420 participants

PRIMA Intervention for Adults With Mild Cognitive Impairment and Their Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2021-12-13

Completion:

2025-07-20

Conditions

• Mild Cognitive Impairment

Interventions

• BEHAVIORAL

Results Available

NCT04493281 | COMPLETED | PHASE1

42 participants

Bioequivalence Study of Oral Suspension and Intravenous Formulation of Edaravone in Healthy Adult Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2019-03-22

Completion:

2019-04-21

Conditions

• Healthy Adult Subjects

Interventions

• DRUG

Results Available

NCT04481789 | COMPLETED | PHASE1

84 participants

Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2018-10-17

Completion:

2018-12-20

Conditions

• Healthy Adult Subjects

Interventions

• DRUG

Results Available

NCT04441554 | RECRUITING

600 participants

7 Tesla MRI Evaluation of the Spine

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-15

Start Date:

2020-03-04

Completion:

2027-09-30

Conditions

• Magnetic Resonance Imaging
• Cervical Spine Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04407247 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

47 participants

Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-07-09

Completion:

2027-12-31

Conditions

• Colitis
• Lung Non-Small Cell Carcinoma
• Malignant Genitourinary System Neoplasm
• Malignant Solid Neoplasm
• Melanoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04404465 | ENROLLING_BY_INVITATION

3000 participants

Health eHeart BEAT-AFib - Health eHeart Biomarkers of Early Atrial Transformation in Atrial Fibrillation

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-15

Start Date:

2020-09-15

Completion:

2030-09-15

Conditions

• Atrial Fibrillation

No Results Yet

NCT04374877 | COMPLETED | PHASE1

145 participants

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-04-22

Completion:

2025-05-28

Conditions

• Advanced Solid Tumor
• Clear Cell Renal Cell Carcinoma
• Hepatocellular Carcinoma
• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04367506 | COMPLETED | NA

59 participants

Pilot Testing a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2022-09-06

Completion:

2024-03-25

Conditions

• Tobacco Cessation

Interventions

• BEHAVIORAL

Results Available

NCT04287049 | COMPLETED | PHASE2

10 participants

A Study of Standard Drugs for Mycobacterium Avium Complex

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-02-24

Completion:

2025-03-21

Conditions

• Mycobacterium Avium Complex

Interventions

• DRUG

Results Available

NCT04284774 | ACTIVE_NOT_RECRUITING | PHASE2

5 participants

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-10-13

Completion:

2024-03-31

Conditions

• Malignant Solid Neoplasm
• Recurrent Adrenal Gland Pheochromocytoma
• Recurrent Ectomesenchymoma
• Recurrent Ependymoma
• Recurrent Ewing Sarcoma
• Recurrent Hepatoblastoma
• Recurrent Kidney Wilms Tumor
• Recurrent Langerhans Cell Histiocytosis
• Recurrent Malignant Germ Cell Tumor
• Recurrent Malignant Glioma
• Recurrent Medulloblastoma
• Recurrent Melanoma
• Recurrent Neuroblastoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Osteosarcoma
• Recurrent Peripheral Primitive Neuroectodermal Tumor
• Recurrent Rhabdoid Tumor
• Recurrent Rhabdoid Tumor of the Kidney
• Recurrent Rhabdomyosarcoma
• Recurrent Soft Tissue Sarcoma
• Recurrent Thyroid Gland Carcinoma
• Recurrent WHO Grade 2 Glioma
• Refractory Adrenal Gland Pheochromocytoma
• Refractory Ependymoma
• Refractory Ewing Sarcoma
• Refractory Hepatoblastoma
• Refractory Langerhans Cell Histiocytosis
• Refractory Malignant Germ Cell Tumor
• Refractory Malignant Glioma
• Refractory Medulloblastoma
• Refractory Melanoma
• Refractory Neuroblastoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Osteosarcoma
• Refractory Peripheral Primitive Neuroectodermal Tumor
• Refractory Rhabdoid Tumor
• Refractory Rhabdoid Tumor of the Kidney
• Refractory Rhabdomyosarcoma
• Refractory Soft Tissue Sarcoma
• Refractory Thyroid Gland Carcinoma
• Refractory WHO Grade 2 Glioma

Interventions

• DRUG

Results Available

NCT04267887 | ACTIVE_NOT_RECRUITING | PHASE2

7 participants

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-05-11

Completion:

2028-01-01

Conditions

• Castration-Sensitive Prostate Carcinoma
• Metastatic Prostate Carcinoma
• Stage IVB Prostate Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• OTHER

No Results Yet

NCT04234841 | RECRUITING

750 participants

Avr Thrombosis OutcoMe Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-15

Start Date:

2020-02-01

Completion:

2028-01-31

Conditions

• Aortic Stenosis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04217551 | COMPLETED | NA

1158 participants

Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-05-18

Completion:

2025-08-25

Conditions

• Cardiac Arrest, Out-Of-Hospital
• Hypothermia, Induced
• Hypoxia-Ischemia, Brain

Interventions

• DEVICE

No Results Yet

NCT04176224 | COMPLETED | PHASE1

9 participants

Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2019-04-17

Completion:

2019-09-04

Conditions

• Japanese Patients With ALS

Interventions

• DRUG

Results Available

NCT04122001 | ACTIVE_NOT_RECRUITING | NA

90 participants

Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-08-17

Completion:

2026-11-30

Conditions

• Alzheimer Disease, Early Onset
• Atypical Alzheimer's Disease
• Logopenic Progressive Aphasia

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04096430 | RECRUITING | NA

96 participants

Evaluation of Effectiveness of Child-oriented Goal-setting in Paediatric Rehabilitation (the ENGAGE Approach)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2022-03-01

Completion:

2026-08-31

Conditions

• Autism Spectrum Disorder
• Neurodevelopmental Disorders
• Cerebral Palsy

Interventions

• BEHAVIORAL

No Results Yet

NCT04038619 | RECRUITING | PHASE1

40 participants

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2021-02-01

Completion:

2027-12-31

Conditions

• Cervical Cancer
• Colitis
• Diarrhea
• Malignant Genitourinary System Neoplasm
• Melanoma
• Lung Cancer
• Ovarian Cancer
• Uterine Cancer
• Breast Cancer

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04029090 | COMPLETED | PHASE1

27 participants

A Study to Evaluate the Effect of MCI-186 at Therapeutic and Supra-Therapeutic Doses on the QT Interval(QT)/Corrected QT Interval(QTc) Interval in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2018-09-18

Completion:

2018-10-20

Conditions

• Healthy Adult Subjects

Interventions

• DRUG

Results Available

NCT04018638 | ACTIVE_NOT_RECRUITING | NA

30 participants

Blood-Flow Restriction Exercise Following a Knee Replacement

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2019-06-25

Completion:

2027-12-25

Conditions

• Knee Injuries
• Knee Osteoarthritis
• Knee Arthritis

Interventions

• OTHER

No Results Yet

NCT03960827 | COMPLETED | NA

1836 participants

Molecular Transducers of Physical Activity Consortium

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2019-08-28

Completion:

2025-05-31

Conditions

• Physical Activity

Interventions

• OTHER

Results Available

NCT03952962 | RECRUITING | NA

12 participants

Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2022-10-28

Completion:

2027-07-31

Conditions

• Treatment Resistant Depression
• Undergoing Deep Brain Stimulation (DBS) Surgery

Interventions

• DEVICE

No Results Yet

NCT03913169 | COMPLETED | NA

1806 participants

Interprofessional Practice Education for Health Professional Students

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2015-08-19

Completion:

2020-12-30

Conditions

• Interprofessional Relations

Interventions

• OTHER

No Results Yet

NCT03896568 | RECRUITING | PHASE1

36 participants

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2019-02-12

Completion:

2027-09-30

Conditions

• IDH1 wt Allele
• Recurrent Anaplastic Astrocytoma
• Recurrent Glioblastoma
• Recurrent Gliosarcoma
• Recurrent Malignant Glioma

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT03891446 | COMPLETED | PHASE3

455 participants

Long-term Safety and Efficacy Extension Trial of Bimatoprost SR

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2019-03-27

Completion:

2026-06-19

Conditions

• Open-Angle Glaucoma
• Ocular Hypertension

Interventions

• DRUG
• OTHER

No Results Yet

NCT03843528 | ACTIVE_NOT_RECRUITING | PHASE1

15 participants

Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2019-05-01

Completion:

2027-07-30

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndromes
• Mixed Phenotype Acute Leukemia
• Juvenile Myelomonocytic Leukemia

Interventions

• DRUG

No Results Yet

NCT03824210 | COMPLETED

50 participants

A Study to Co-produce a Young Carers App

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-15

Start Date:

2019-03-20

Completion:

2020-12-01

Conditions

• Caring

Interventions

• OTHER

No Results Yet

NCT03819296 | RECRUITING | PHASE1

800 participants

Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2021-02-21

Completion:

2026-10-31

Conditions

• Clinical Stage 0 Cutaneous Melanoma AJCC v8
• Clinical Stage I Cutaneous Melanoma AJCC v8
• Clinical Stage IA Cutaneous Melanoma AJCC v8
• Clinical Stage IB Cutaneous Melanoma AJCC v8
• Clinical Stage II Cutaneous Melanoma AJCC v8
• Clinical Stage IIA Cutaneous Melanoma AJCC v8
• Clinical Stage IIB Cutaneous Melanoma AJCC v8
• Clinical Stage IIC Cutaneous Melanoma AJCC v8
• Clinical Stage III Cutaneous Melanoma AJCC v8
• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Colitis
• Lung Non-Small Cell Carcinoma
• Malignant Genitourinary System Neoplasm
• Malignant Solid Neoplasm
• Pathologic Stage 0 Cutaneous Melanoma AJCC v8
• Pathologic Stage I Cutaneous Melanoma AJCC v8
• Pathologic Stage IA Cutaneous Melanoma AJCC v8
• Pathologic Stage IB Cutaneous Melanoma AJCC v8
• Pathologic Stage II Cutaneous Melanoma AJCC v8
• Pathologic Stage IIA Cutaneous Melanoma AJCC v8
• Pathologic Stage IIB Cutaneous Melanoma AJCC v8
• Pathologic Stage IIC Cutaneous Melanoma AJCC v8
• Pathologic Stage III Cutaneous Melanoma AJCC v8
• Pathologic Stage IIIA Cutaneous Melanoma AJCC v8
• Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
• Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
• Pathologic Stage IIID Cutaneous Melanoma AJCC v8
• Pathologic Stage IV Cutaneous Melanoma AJCC v8
• Stage 0 Lung Cancer AJCC v8
• Stage I Lung Cancer AJCC v8
• Stage IA1 Lung Cancer AJCC v8
• Stage IA2 Lung Cancer AJCC v8
• Stage IA3 Lung Cancer AJCC v8
• Stage IB Lung Cancer AJCC v8
• Stage II Lung Cancer AJCC v8
• Stage IIA Lung Cancer AJCC v8
• Stage IIB Lung Cancer AJCC v8
• Stage III Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• OTHER
• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT03778957 | ACTIVE_NOT_RECRUITING | PHASE3

724 participants

A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2018-11-30

Completion:

2023-09-11

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG
• OTHER
• PROCEDURE

No Results Yet

NCT03682081 | COMPLETED | NA

76 participants

Interventions for Patients With Alzheimer's Disease and Dysphagia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2020-09-25

Completion:

2025-08-30

Conditions

• Dementia
• Dysphagia
• Alzheimer Disease

Interventions

• DEVICE

No Results Yet

NCT03664544 | COMPLETED | PHASE1

12 participants

PK Study in Subjects With Severe Hepatic Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2018-11-06

Completion:

2019-03-25

Conditions

• Severe Hepatic Impairment
• Healthy

Interventions

• DRUG

Results Available

NCT03655782 | ACTIVE_NOT_RECRUITING | NA

90 participants

Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2023-07-01

Completion:

2029-07-30

Conditions

• MTBI - Mild Traumatic Brain Injury

Interventions

• BEHAVIORAL

No Results Yet

NCT03456076 | ACTIVE_NOT_RECRUITING | PHASE3

257 participants

A Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2018-08-16

Completion:

2023-06-26

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT03418181 | COMPLETED | NA

44 participants

Does Incremental Initiation of Haemodialysis Preserve Native Kidney Function?

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2018-01-08

Completion:

2020-05-02

Conditions

• Kidney Failure
• Dialysis

Interventions

• PROCEDURE

No Results Yet

NCT03384836 | SUSPENDED | PHASE1/PHASE2

47 participants

Propranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2018-01-31

Completion:

2027-05-31

Conditions

• Stage IIIC Cutaneous Melanoma AJCC v7
• Stage IV Cutaneous Melanoma AJCC v6 and v7

Interventions

• OTHER
• BIOLOGICAL
• DRUG

No Results Yet

NCT03317158 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

186 participants

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2017-11-21

Completion:

2028-12-31

Conditions

• Urothelial Carcinoma
• Bladder Cancer

Interventions

• DRUG
• RADIATION
• BIOLOGICAL
• OTHER

No Results Yet

NCT03289234 | COMPLETED | PHASE1

22 participants

Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Hepatic Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2016-11-16

Completion:

2018-07-20

Conditions

• Hepatic Impairment
• Healthy

Interventions

• DRUG

Results Available

NCT03289208 | COMPLETED | PHASE1

30 participants

Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Renal Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-15

Start Date:

2016-10-27

Completion:

2018-04-16

Conditions

• Renal Impairment
• Healthy

Interventions

• DRUG

Results Available