Clinical Trials

NCT06976944 | RECRUITING | PHASE2

24 participants

Pembrolizumab + Paclitaxel +/- Bevacizumab for Triple-negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-06-24

Completion:

2029-09-30

Conditions

• Recurrent Triple-Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06970912 | RECRUITING | PHASE2

393 participants

ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-08-01

Completion:

2029-12-31

Conditions

• Hormone Receptor-Positive Breast Cancer
• High-risk Breast Cancer
• Early-Stage Breast Cancer
• HER2-negative Breast Cancer
• ctDNA Monitoring
• Breast Cancer Early Stage Breast Cancer (Stage 1-3)

Interventions

• DRUG

No Results Yet

NCT06958835 | RECRUITING | NA

606 participants

Linezolid Plus Standard of Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-10-06

Completion:

2028-10-31

Conditions

• Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)

Interventions

• DRUG

No Results Yet

NCT06953388 | NOT_YET_RECRUITING | EARLY_PHASE1

60 participants

Understanding Non-invasive Vagus Nerve Stimulation Effects in PTSD

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2027-04-01

Completion:

2031-03-01

Conditions

• PTSD - Post Traumatic Stress Disorder

Interventions

• DEVICE

No Results Yet

NCT06950567 | COMPLETED | NA

122 participants

Evaluation of the Effectiveness of a Psychoeducational Intervention on Benzodiazepine Use in the Population Over 64 Years Old in Primary Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-04-01

Completion:

2025-10-15

Conditions

• suspensión Completa Del Tratamiento Con Benzodicepinas
• Disminución Del Consumo Benzodiacepinas

Interventions

• OTHER

No Results Yet

NCT06948955 | AVAILABLE

Expanded Access to Bezuclastinib to be Coadministered With Sunitinib for Patients With Gastrointestinal Stromal Tumors

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-07-13

Conditions

• Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors

Interventions

• DRUG

No Results Yet

NCT06940154 | ACTIVE_NOT_RECRUITING | PHASE2

160 participants

Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-08-12

Completion:

2026-07-30

Conditions

• COPD Acute Exacerbation

Interventions

• COMBINATION_PRODUCT
• DRUG

No Results Yet

NCT06915766 | AVAILABLE

Expanded Access to Bezuclastinib for Patients With NonAdvanced Systemic Mastocytosis or Advanced Systemic Mastocytosis

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-07-13

Conditions

• Systemic Mastocytoses, Indolent
• Systemic Mastocytoses, Aggressive

Interventions

• DRUG

No Results Yet

NCT06912685 | NOT_YET_RECRUITING | NA

62 participants

Early Test of an Innovative Child Maltreatment (CM) Prevention Strategy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2027-01-01

Completion:

2027-10-01

Conditions

• Parenting Intervention
• Maltreatment
• Prevention

Interventions

• OTHER

No Results Yet

NCT06903936 | COMPLETED | NA

68 participants

Comparison of the Effect of Genicular Nerve Block and Physical Therapy in Patients With Knee Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-09-01

Completion:

2026-03-01

Conditions

• Knee Osteoarthritis

Interventions

• OTHER

No Results Yet

NCT06899217 | COMPLETED | PHASE2

416 participants

A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adult Subjects With Idiopathic Gastroparesis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-01-29

Completion:

2026-05-07

Conditions

• Idiopathic Gastroparesis

Interventions

• DRUG

No Results Yet

NCT06889610 | RECRUITING | PHASE2

95 participants

A Phase II Clinical Study of Multimodal Ablation Combined With Systemic Drug Therapy for Advanced Solid Tumors.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2026-03-30

Completion:

2027-12-30

Conditions

• Triple Negative Breast Cancer Metastatic
• Melanoma Metastatic
• Colorectal Cancer Metastatic

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06888817 | RECRUITING | PHASE3

408 participants

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-06-19

Completion:

2028-07-31

Conditions

• Radiation Necrosis
• High Grade Glioma (III or IV)
• Brain Metastasases
• Radiation Toxicity
• Radiation Effect
• Radiation Injury
• Radiation Injuries

Interventions

• DRUG

No Results Yet

NCT06886477 | COMPLETED | NA

37 participants

Sickle Cell, Pain and Mediterranean Diet

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-05-01

Completion:

2026-07-09

Conditions

• Sickle Cell
• Sickle Cell Disease
• Sickle Cell Disease Without Crisis
• Mediterranean Diet

Interventions

• OTHER

No Results Yet

NCT06885047 | NOT_YET_RECRUITING | NA

60 participants

Culturally Centered CBT Protocol for Suicidal Behaviors Among Youth in Mexico City

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2026-09-30

Completion:

2027-06-30

Conditions

• Suicidal Ideation/Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT06883344 | RECRUITING | NA

150 participants

Automated Insulin for Management of Intrapartum Glycemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-12-05

Completion:

2028-12-31

Conditions

• Type 1 Diabetes (T1D)
• Pregnancy
• Pre-Gestational Diabetes

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06879145 | RECRUITING | PHASE2/PHASE3

840 participants

Clinical Study on the Treatment of MIBC Patients With SHR-A2102 Injection Combined With Adebrelimab (SHR-1316)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-04-25

Completion:

2031-12-31

Conditions

• Muscular Invasive Bladder Cancer (MIBC)

Interventions

• DRUG

No Results Yet

NCT06876532 | RECRUITING | NA

150 participants

Evaluation of the Inflammation-based Index as a Predictive Marker of Clinical and Radiological Response in Patients Treated With Lu-177 Oxodotreotide for Intestinal Neuroendocrine Tumour

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-04-07

Completion:

2029-04-30

Conditions

• Intestinal Neuroendocrine Tumor

Interventions

• OTHER

No Results Yet

NCT06870760 | RECRUITING

300 participants

Pre-malignant States to Hematologic Malignancies in Firefighters

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2026-06-23

Completion:

2027-04-30

Conditions

• Clonal Hematopoiesis of Indeterminate Potential
• Monoclonal Gammopathy
• Non Hodgkin Lymphoma
• Leukemia
• Multiple Myeloma
• Plasma Cell Disorder

Interventions

• OTHER

No Results Yet

NCT06865885 | RECRUITING | PHASE4

100 participants

LDL-C Optimization Using Inclisiran in Patients in Which Drug-Drug Interactions Limit LDL Lowering

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-04-02

Completion:

2026-12-30

Conditions

• Drug Interactions
• Primary Prevention
• Cardiometabolic Syndrome
• LDL-Cholersterol Lowering

Interventions

• DRUG

No Results Yet

NCT06859788 | ACTIVE_NOT_RECRUITING | PHASE3

200 participants

SPI-1005 for the Treatment of Meniere's Disease (Open Label)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-10-29

Completion:

2026-12-31

Conditions

• Meniere's Disease
• Ménière's Disease

Interventions

• DRUG

No Results Yet

NCT06859099 | ENROLLING_BY_INVITATION | PHASE3

300 participants

Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-04-01

Completion:

2029-10-03

Conditions

• Polyneuropathy, Inflammatory Demyelinating, Chronic

Interventions

• DRUG

No Results Yet

NCT06855758 | ACTIVE_NOT_RECRUITING | NA

150 participants

Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-06

Completion:

2026-06-15

Conditions

• Kidney Transplant
• Delayed Graft Function
• Intraoperative Hypotension

Interventions

• DRUG

No Results Yet

NCT06848088 | ENROLLING_BY_INVITATION | PHASE2

48 participants

A Study to Learn About the Long-Term Health of Adult Participants From a Previous Study of a New Melanoma Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-04-14

Completion:

2029-10-10

Conditions

• Melanoma

Interventions

• DRUG

No Results Yet

NCT06836141 | RECRUITING

118 participants

Biomarkers for Cognitive Decline in Intracerebral Hemorrhage

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2025-08-02

Completion:

2029-08-01

Conditions

• Primary Intracerebral Hemorrhage

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06835920 | COMPLETED | NA

724 participants

Alcohol Labeling Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-04-28

Completion:

2026-05-29

Conditions

• Health Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT06834581 | ACTIVE_NOT_RECRUITING | NA

12 participants

Effects of Vibrating Mesh Nebulisation in Patients on Long-term Tracheostomy Ventilation: a Pilot Randomised Crossover Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-20

Completion:

2025-09-10

Conditions

• Long-term Tracheostomy Ventilated Patients

Interventions

• DEVICE

No Results Yet

NCT06822387 | ACTIVE_NOT_RECRUITING | NA

140 participants

Health Without Barriers/Salud Sin Barreras- Northern Colorado

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-04-07

Completion:

2026-12-31

Conditions

• Lifestyle Risk Reduction
• Adolescent Health
• Family Health
• Cardio-metabolic Health
• Mental Health
• Wellness Program
• Type 2 Diabetes
• Obesity, Adolescent

Interventions

• BEHAVIORAL

No Results Yet

NCT06816498 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

1 participants

Personalized Antisense Oligonucleotide Therapy for A Single Participant With LMNB1 Mutation Associated Autosomal Dominant Leukodystrophy (ADLD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-17

Completion:

2027-03-31

Conditions

• Autosomal Dominant Leukodystrophy

Interventions

• DRUG

No Results Yet

NCT06805513 | COMPLETED | PHASE3

2212 participants

Actual Use Trial of Tadalafil 5 mg

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-01-30

Completion:

2026-03-02

Conditions

• Erectile Dysfunction

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06796543 | RECRUITING | NA

70 participants

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-25

Completion:

2028-03-31

Conditions

• Metastatic Sarcoma
• Radiation Therapy Patient
• Ewing Sarcoma
• Rhabdomyosarcoma

Interventions

• RADIATION

No Results Yet

NCT06787729 | RECRUITING | NA

50 participants

At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2026-04-20

Completion:

2027-01-31

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT06785129 | RECRUITING

120 participants

Endometriosis and Migraine

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2025-02-12

Completion:

2028-01-01

Conditions

• Migraine
• Endometriosis

Interventions

• DEVICE
• BEHAVIORAL
• BIOLOGICAL

No Results Yet

NCT06784063 | COMPLETED | NA

40 participants

Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-04-10

Completion:

2025-06-13

Conditions

• Astigmatism

Interventions

• DEVICE

Results Available

NCT06762275 | RECRUITING | NA

566 participants

The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-06

Completion:

2028-03-31

Conditions

• Appendicitis Acute
• Acute Abdomen in Children

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06754774 | COMPLETED | NA

40 participants

Shoulder Endurance Test: Normative Values in a Population of Female Handball Players Aged 14 to 18 in Intensive Training Structures.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-12-18

Completion:

2025-05-19

Conditions

• Healthy Subjects 14 to 18 Years Old

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06750432 | ACTIVE_NOT_RECRUITING | PHASE1

144 participants

PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-12-13

Completion:

2026-12-31

Conditions

• Alzheimer Disease, Early Onset

Interventions

• DRUG

No Results Yet

NCT06740890 | RECRUITING | PHASE4

30 participants

Exercise and Olanzapine-samidorphan

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-06-26

Completion:

2027-04-30

Conditions

• Schizophenia Disorder
• Schizoaffective Disorder
• Bipolar Disorder I or II
• Bipolar Disorder NOS

Interventions

• DRUG

No Results Yet

NCT06725030 | RECRUITING

455 participants

A Post-market, Real-world Experience: Expanding Access to Care by Incorporating the Symani® Surgical System and Enabling Surgeons

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2025-09-22

Completion:

2027-09-01

Conditions

• Open Surgery
• Lymphedema
• Free Tissue Transfer
• Microsurgery
• Anastomosis, Surgical

Interventions

• DEVICE

No Results Yet

NCT06703476 | RECRUITING | PHASE3

530 participants

A Study of Surgical Techniques During Cystectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-11-21

Completion:

2028-11-30

Conditions

• Bladder Cancer

Interventions

• PROCEDURE
• DRUG

No Results Yet