Clinical Trials

NCT04629547 | RECRUITING | PHASE2

120 participants

Sleep Trial to Prevent Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2022-05-25

Completion:

2028-05-31

Conditions

• Sleep
• Alzheimer Disease

Interventions

• DRUG

No Results Yet

NCT04626154 | RECRUITING | NA

20 participants

Thoracoabdominal Asynchrony and Respiratory Distress

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-10-16

Completion:

2028-04-30

Conditions

• Respiratory Insufficiency

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04625127 | ACTIVE_NOT_RECRUITING | NA

76 participants

GaitBetter: Motor and Cognitive Training for Gait Rehabilitation and Falls Prevention in Stroke Survivors.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2021-07-23

Completion:

2026-08-31

Conditions

• Stroke
• Gait, Hemiplegic
• Hemiplegia

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04604314 | COMPLETED | NA

69 participants

Alternative EndoCrowns Designs for Chairside CAD/CAM

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-12-10

Completion:

2025-05-08

Conditions

• Endodontically Treated Teeth

Interventions

• DEVICE

Results Available

NCT04601038 | RECRUITING | PHASE2

52 participants

Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2021-06-28

Completion:

2027-11-30

Conditions

• Mild Cognitive Impairment
• Alzheimer Disease
• Memory Impairment

Interventions

• DRUG

No Results Yet

NCT04589208 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

35 participants

Glutamatergic Mechanisms of Psychosis and Target Engagement (SA1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2021-01-01

Completion:

2027-01-01

Conditions

• Healthy

Interventions

• DRUG

No Results Yet

NCT04577599 | RECRUITING | NA

1160 participants

Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2021-01-07

Completion:

2028-10-31

Conditions

• Lung Neoplasms
• Lung Cancer

Interventions

• OTHER

No Results Yet

NCT04571372 | COMPLETED

222 participants

Prognostic Value of Soluble Urokinase-type Plasminogen Activator Receptor in Valvular Heart Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2020-08-14

Completion:

2025-12-13

Conditions

• Severe Aortic Stenosis or Severe Aortic Regurgitation

No Results Yet

NCT04552834 | ACTIVE_NOT_RECRUITING

500 participants

Alterations of the Microbiome During Critical Illness With Short and Long Term Clinical Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2020-09-15

Completion:

2027-11-01

Conditions

• Critical Illness
• Microbiome

No Results Yet

NCT04533165 | ACTIVE_NOT_RECRUITING | NA

19 participants

Virtual Exercise Program to Reduce Cancer Related Fatigue

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2021-11-11

Completion:

2023-04-12

Conditions

• Cancer
• Cancer-related Problem/Condition
• Fatigue

Interventions

• BEHAVIORAL

No Results Yet

NCT04454073 | ACTIVE_NOT_RECRUITING

87 participants

Investigation of Factors Associated With Preserved Cognitive Function in Bipolar Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2021-10-29

Completion:

2024-05-01

Conditions

• Bipolar Disorder

No Results Yet

NCT04443348 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Pre-op Pembro + Radiation Therapy in Breast Cancer (P-RAD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-12-16

Completion:

2025-12-31

Conditions

• Triple Negative Breast Cancer
• Hormone Receptor Positive (HR+), HER2-negative Breast Cancer
• Biopsy-proven, Positive Lymph Node(s)

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04411199 | COMPLETED | PHASE3

975 participants

D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-12-15

Completion:

2025-04-14

Conditions

• Surgical Site Infection
• Colon Surgery
• Abdominal Surgery
• Post-Op Infection

Interventions

• DRUG
• OTHER

Results Available

NCT04360538 | ACTIVE_NOT_RECRUITING

500 participants

Long Term Outcomes of Patients With COVID-19

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2020-04-08

Completion:

2026-11-01

Conditions

• Critical Illness
• Corona Virus Infection
• Respiratory Failure
• Covid-19

Interventions

• OTHER

No Results Yet

NCT04334668 | ACTIVE_NOT_RECRUITING | NA

67 participants

Oral Sodium to Preserve Renal EfficiencY in Acute Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-05-20

Completion:

2022-06-01

Conditions

• Volume Overload

Interventions

• DIETARY_SUPPLEMENT
• OTHER

Results Available

NCT04267588 | RECRUITING

100 participants

Using Technology to Track Pain and Pain-related Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2020-08-10

Completion:

2027-06-30

Conditions

• Pain, Chronic

Interventions

• OTHER

No Results Yet

NCT04266197 | COMPLETED | PHASE2

42 participants

Vardenafil Inhaled for Pulmonary Arterial Hypertension PRN Phase 2B Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-09-25

Completion:

2024-11-20

Conditions

• Pulmonary Arterial Hypertension

Interventions

• COMBINATION_PRODUCT

Results Available

NCT04248517 | COMPLETED | NA

23 participants

Using mHealth to Optimize Pharmacotherapy Regimens

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-10-09

Completion:

2022-12-31

Conditions

• Schizophrenia
• First-Episode Psychosis

Interventions

• OTHER

No Results Yet

NCT04208919 | COMPLETED | PHASE1/PHASE2

16 participants

Delayed Infusion of DCreg in Living Donor Liver Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2019-12-18

Completion:

2025-12-03

Conditions

• Living Donor Liver Transplantation

Interventions

• BIOLOGICAL

No Results Yet

NCT04194892 | COMPLETED | PHASE1

12 participants

A Crossover Study to Evaluate Pegilodecakin (LY3500518) in Healthy Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2018-01-19

Completion:

2018-03-14

Conditions

• Healthy Adult Subjects

Interventions

• BIOLOGICAL

Results Available

NCT04187131 | RECRUITING | NA

10 participants

An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2023-06-01

Completion:

2028-09-30

Conditions

• Stroke

Interventions

• BEHAVIORAL

No Results Yet

NCT04182776 | ACTIVE_NOT_RECRUITING

420 participants

Fragility Fractures of the Pelvis (FFP)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2022-03-01

Completion:

2027-07-31

Conditions

• Pelvic Fracture

No Results Yet

NCT04177004 | ACTIVE_NOT_RECRUITING | PHASE1

52 participants

Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2021-04-30

Completion:

2025-12-29

Conditions

• Allogeneic Hematopoietic Stem Cell Transplant Recipient
• Hematopoietic and Lymphoid Cell Neoplasm

Interventions

• PROCEDURE
• DRUG
• RADIATION
• BIOLOGICAL

No Results Yet

NCT04174742 | ACTIVE_NOT_RECRUITING

115 participants

Self Reported Pain in Women While Undergoing Treatment for Non-metastatic Breast Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2019-12-17

Completion:

2041-01-31

Conditions

• Breast
• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04158141 | TERMINATED | PHASE3

16 participants

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-01-29

Completion:

2023-11-20

Conditions

• Pleural Biphasic Mesothelioma
• Pleural Epithelioid Mesothelioma
• Stage I Pleural Malignant Mesothelioma AJCC v8
• Stage IA Pleural Malignant Mesothelioma AJCC v8
• Stage IB Pleural Malignant Mesothelioma AJCC v8
• Stage II Pleural Malignant Mesothelioma AJCC v8
• Stage IIIA Pleural Malignant Mesothelioma AJCC v8

Interventions

• DRUG
• PROCEDURE
• RADIATION

Results Available

NCT04149457 | COMPLETED | NA

93 participants

Improving Neurological Health in Aging Via Neuroplasticity-based Computerized Exercise

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2021-07-16

Completion:

2024-06-07

Conditions

• Healthy Aging

Interventions

• OTHER

Results Available

NCT04130516 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

200 participants

Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2019-10-21

Completion:

2026-06-30

Conditions

• Solid Tumor, Adult

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04114279 | WITHDRAWN | NA

0 participants

Validation of a Totally Synthetic High Fidelity Laparoscopic Duodenal Atresia (DA) Surgical Simulator

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-04-28

Completion:

2020-04-28

Conditions

• Duodenal Atresia

Interventions

• PROCEDURE

No Results Yet

NCT04067674 | RECRUITING

305 participants

Septic Shock-induced Immunosuppression

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2019-10-21

Completion:

2026-11-21

Conditions

• Septic Shock

Interventions

• BIOLOGICAL

No Results Yet

NCT04060927 | ACTIVE_NOT_RECRUITING | NA

45 participants

Pilot Study of SGRT Alone vs. SGRT With Fiducials for Breath Hold SBRT tx of the Lung

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2019-09-25

Completion:

2025-10-18

Conditions

• Lung Cancer

Interventions

• DEVICE

No Results Yet

NCT04056988 | COMPLETED | PHASE4

27 participants

tSCI Contrast Enhanced Ultrasound Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2018-07-31

Completion:

2023-11-20

Conditions

• Acute Spinal Cord Injury

Interventions

• DRUG

Results Available

NCT04046575 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Radiation Dose Intensification With Accelerated Hypofractionated Intensity Modulated Radiation Therapy and Concurrent Carboplatin and Paclitaxel for Inoperable Esophageal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2019-11-07

Completion:

2025-06-02

Conditions

• Esophagus Cancer
• Esophageal Cancer
• Cancer of the Esophagus

Interventions

• RADIATION
• DRUG
• OTHER
• PROCEDURE

No Results Yet

NCT04044534 | COMPLETED | PHASE2

10 participants

Intranasal Insulin for Posttraumatic Stress Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-10-31

Completion:

2026-05-28

Conditions

• PTSD

Interventions

• DRUG

Results Available

NCT04039971 | ACTIVE_NOT_RECRUITING | NA

150 participants

Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2020-08-01

Completion:

2029-08-31

Conditions

• Anterior Cruciate Ligament Injuries
• Anterior Cruciate Ligament Rupture
• Anterior Cruciate Ligament Tear

Interventions

• PROCEDURE

No Results Yet

NCT03985839 | COMPLETED

298 participants

Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and Hip

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2019-08-01

Completion:

2024-08-08

Conditions

• Labral Tear, Glenoid
• Acetabular Labrum Tear
• Bankart Lesions
• Anterior Shoulder Instability
• SLAP Lesion
• Rotator Cuff Tears

Interventions

• DEVICE

Results Available

NCT03933696 | COMPLETED | NA

25 participants

Light, Metabolic Syndrome and Alzheimer's Disease - Aim 2

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2019-01-02

Completion:

2025-05-31

Conditions

• Mild Cognitive Impairment
• Alzheimer Disease
• Type2 Diabetes

Interventions

• DEVICE

No Results Yet

NCT03912519 | ENROLLING_BY_INVITATION | NA

132 participants

Parallel Versus Perpendicular Technique for Lumbar Medial Branch Radiofrequency Neurotomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2019-08-21

Completion:

2027-12-31

Conditions

• Back Pain Without Radiation
• Low Back Pain
• Lumbar Radiofrequency Neurotomy

Interventions

• PROCEDURE

No Results Yet

NCT03905668 | ACTIVE_NOT_RECRUITING

71 participants

Fundamental Intelligent Building Blocks of the Intensive Care Unit (ICU) of the Future: Intelligent ICU of the Future

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2016-02-03

Completion:

2022-01-18

Conditions

• Pain
• Delirium

Interventions

• OTHER

No Results Yet

NCT03901924 | RECRUITING | NA

468 participants

Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2019-03-04

Completion:

2027-05-31

Conditions

• Mechanical Ventilation Complication

Interventions

• OTHER

No Results Yet

NCT03886961 | RECRUITING | NA

20 participants

The Effect of the Reflux Band™ Upper Esophageal Sphincter (UES) Assist Device on Reflux for Lung Transplant Recipients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2019-05-17

Completion:

2027-03-20

Conditions

• Lung Transplant
• GERD

Interventions

• DEVICE

No Results Yet