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Clinical Trials

NCT04166318 | ACTIVE_NOT_RECRUITING | PHASE2
252 participants

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2020-01-02
Completion:
2029-12-31
Conditions
  • Anal Basaloid Carcinoma
  • Anal Canal Cloacogenic Carcinoma
  • Anal Canal Squamous Cell Carcinoma
  • Anal Margin Squamous Cell Carcinoma
  • Stage I Anal Cancer AJCC v8
  • Stage IIA Anal Cancer AJCC v8
Interventions
  • DRUG
  • PROCEDURE
  • OTHER
  • RADIATION
No Results Yet
NCT04108156 | ACTIVE_NOT_RECRUITING | PHASE3
672 participants

A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DME

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2019-09-30
Completion:
2027-07-20
Conditions
  • Diabetic Macular Edema
Interventions
  • DRUG
No Results Yet
NCT04037254 | COMPLETED | PHASE1/PHASE2
22 participants

Testing the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Therapy) for Prostate Cancer With a High Chance of Recurring

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2019-10-08
Completion:
2024-07-01
Conditions
  • Prostate Adenocarcinoma
  • Stage IIC Prostate Cancer AJCC v8
  • Stage III Prostate Cancer AJCC v8
  • Stage IIIA Prostate Cancer AJCC v8
  • Stage IIIB Prostate Cancer AJCC v8
  • Stage IIIC Prostate Cancer AJCC v8
  • Stage IVA Prostate Cancer AJCC v8
Interventions
  • BIOLOGICAL
  • RADIATION
  • DRUG
Results Available
NCT03942328 | RECRUITING | PHASE1/PHASE2
85 participants

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2019-09-19
Completion:
2030-05-31
Conditions
  • Stage III Hepatocellular Carcinoma AJCC v8
  • Stage III Intrahepatic Cholangiocarcinoma AJCC v8
  • Stage IV Hepatocellular Carcinoma AJCC v8
  • Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
  • Unresectable Hepatocellular Carcinoma
  • Unresectable Intrahepatic Cholangiocarcinoma
Interventions
  • BIOLOGICAL
  • RADIATION
  • PROCEDURE
No Results Yet
NCT03919071 | ACTIVE_NOT_RECRUITING | PHASE2
58 participants

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2020-02-20
Completion:
2027-09-30
Conditions
  • Anaplastic Astrocytoma
  • Anaplastic Astrocytoma, Not Otherwise Specified
  • Anaplastic Ganglioglioma
  • Anaplastic Pleomorphic Xanthoastrocytoma
  • Glioblastoma
  • Malignant Glioma
  • WHO Grade 3 Glioma
  • WHO Grade 4 Glioma
Interventions
  • PROCEDURE
  • DRUG
  • RADIATION
No Results Yet
NCT03772977 | ACTIVE_NOT_RECRUITING | NA
95 participants

The Brain Health Champion Study

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2017-05-08
Completion:
2024-07-01
Conditions
  • Mild Cognitive Impairment
  • Dementia, Mild
  • Subjective Cognitive Decline
  • At Risk for Cognitive Decline
Interventions
  • BEHAVIORAL
No Results Yet
NCT03766126 | TERMINATED | PHASE1
22 participants

Lentivirally Redirected CD123 Autologous T Cells in AML

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2018-12-06
Completion:
2026-03-05
Conditions
  • Acute Myeloid Leukemia, in Relapse
  • Acute Myeloid Leukemia, Adult
  • Acute Myeloid Leukemia, Refractory
Interventions
  • BIOLOGICAL
No Results Yet
NCT03593759 | RECRUITING | PHASE3
160 participants

Cardiac Sarcoidosis Randomized Trial

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2019-01-15
Completion:
2026-12-31
Conditions
  • Cardiac Sarcoidosis
  • Sarcoidosis
Interventions
  • DRUG
No Results Yet
NCT03409718 | ACTIVE_NOT_RECRUITING
160 participants

Database Retrieval for the Comprehensive Shoulder

Study Type:
OBSERVATIONAL
Last Updated:
2026-07-10
Start Date:
2011-02-24
Completion:
2026-12-31
Conditions
  • Osteoarthritis of the Shoulder
  • Avascular Necrosis
  • Rheumatoid Arthritis
  • Prior Failed Revision
  • Correction of Functional Deformity
  • Fracture of Proximal End of Humerus
  • Cuff Tear Arthropathy
Interventions
  • DEVICE
No Results Yet
NCT03399773 | ACTIVE_NOT_RECRUITING | PHASE2
31 participants

Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2022-05-10
Completion:
2025-06-09
Conditions
  • Acute Biphenotypic Leukemia
  • Acute Lymphoblastic Leukemia
  • Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • Hematopoietic and Lymphoid Cell Neoplasm
  • Myelodysplastic Syndrome
  • Myelodysplastic Syndrome With Excess Blasts
Interventions
  • BIOLOGICAL
  • DRUG
  • RADIATION
  • PROCEDURE
  • OTHER
Results Available
NCT03213652 | ACTIVE_NOT_RECRUITING | PHASE2
13 participants

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Study Type:
INTERVENTIONAL
Last Updated:
2026-07-10
Start Date:
2018-04-17
Completion:
2025-09-30
Conditions
  • Advanced Malignant Solid Neoplasm
  • Malignant Solid Neoplasm
  • Recurrent Ependymoma
  • Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
  • Recurrent Hepatoblastoma
  • Recurrent Langerhans Cell Histiocytosis
  • Recurrent Malignant Germ Cell Tumor
  • Recurrent Malignant Glioma
  • Recurrent Malignant Solid Neoplasm
  • Recurrent Medulloblastoma
  • Recurrent Neuroblastoma
  • Recurrent Non-Hodgkin Lymphoma
  • Recurrent Osteosarcoma
  • Recurrent Primary Central Nervous System Neoplasm
  • Recurrent Rhabdoid Tumor
  • Recurrent Rhabdomyosarcoma
  • Recurrent Soft Tissue Sarcoma
  • Refractory Ependymoma
  • Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
  • Refractory Hepatoblastoma
  • Refractory Langerhans Cell Histiocytosis
  • Refractory Malignant Germ Cell Tumor
  • Refractory Malignant Glioma
  • Refractory Malignant Solid Neoplasm
  • Refractory Medulloblastoma
  • Refractory Neuroblastoma
  • Refractory Non-Hodgkin Lymphoma
  • Refractory Osteosarcoma
  • Refractory Primary Central Nervous System Neoplasm
  • Refractory Rhabdoid Tumor
  • Refractory Rhabdomyosarcoma
  • Refractory Soft Tissue Sarcoma
  • Wilms Tumor
Interventions
  • PROCEDURE
  • DRUG
  • OTHER
No Results Yet
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