Clinical Trials

NCT04837222 | COMPLETED

1000 participants

A Study of Brentuximab Vedotin in Adults With CD30-positive Lymphoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-07

Start Date:

2021-06-07

Completion:

2026-06-26

Conditions

• Lymphoma

Interventions

• OTHER

No Results Yet

NCT04824859 | TERMINATED | NA

21 participants

A Geriatric Assessment Electronic Platform for Older Patients With Cancer (eGAP - Electronic Geriatric Assessment Platform)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-12-07

Completion:

2023-04-30

Conditions

• Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04809987 | COMPLETED | NA

38 participants

Effectiveness of Virtual Gait System Intervention in Motor Function in People With Incomplete Spinal Cord Injury.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-01-30

Completion:

2025-12-31

Conditions

• Incomplete Spinal Cord Injury

Interventions

• OTHER

No Results Yet

NCT04808479 | COMPLETED | NA

210 participants

Effectiveness of a CBT-based mHealth Intervention Targeting MOUD Retention, Adherence, and Opioid Use

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2019-12-10

Completion:

2026-06-15

Conditions

• Opioid-use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04777396 | COMPLETED | PHASE3

1840 participants

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-05-18

Completion:

2025-09-16

Conditions

• Early Alzheimer's Disease

Interventions

• DRUG

No Results Yet

NCT04774354 | COMPLETED

350 participants

POSSUM, P-POSSUM, Clinical Frailty Scale, Clinical Frailty Scale and Charlson's Comorbidity Index in Abdominal Surgery.

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-07

Start Date:

2021-03-01

Completion:

2025-03-30

Conditions

• Postoperative Complications

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04765150 | RECRUITING

275 participants

Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer Classification

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-07

Start Date:

2021-04-01

Completion:

2027-06-01

Conditions

• Prostate Carcinoma

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04765059 | ACTIVE_NOT_RECRUITING | PHASE3

98 participants

A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-09-12

Completion:

2024-10-28

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT04717427 | COMPLETED

161 participants

Longitudinal Studies to Identify Biomarkers for Sturge-Weber Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-07

Start Date:

2021-09-08

Completion:

2025-06-30

Conditions

• Sturge-Weber Syndrome

No Results Yet

NCT04701203 | COMPLETED | PHASE3

84 participants

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-02-16

Completion:

2022-01-12

Conditions

• Hypoparathyroidism
• Endocrine System Diseases
• Parathyroid Diseases

Interventions

• COMBINATION_PRODUCT

Results Available

NCT04695600 | RECRUITING | PHASE2/PHASE3

100 participants

Onabotulinum Toxin A (Botox) in the Treatment of Pharyngo-esophageal Dysphagia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2023-08-11

Completion:

2027-08-31

Conditions

• Transfer Dysphagia
• Oropharyngeal Dysphagia
• Cricopharyngeus Muscle Dysfunction

Interventions

• DRUG

No Results Yet

NCT04693988 | COMPLETED | NA

114 participants

Early Case Management on Recovery From a Cardiac Event in Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-01-18

Completion:

2023-12-01

Conditions

• Cardiac Rehabilitation

Interventions

• BEHAVIORAL

Results Available

NCT04666636 | RECRUITING | PHASE2

65 participants

Mechanisms for Activation of Beige Adipose Tissue in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-12-07

Completion:

2027-06-30

Conditions

• PreDiabetes

Interventions

• DRUG

No Results Yet

NCT04660552 | COMPLETED | NA

34 participants

Transcranial Photobiomodulation for Reducing Autism Symptoms in Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-11-15

Completion:

2022-12-31

Conditions

• Autism Spectrum Disorder

Interventions

• DEVICE

Results Available

NCT04638478 | ACTIVE_NOT_RECRUITING

67 participants

PREselection of Patients at Risk for COgnitive DEcline After Radiotherapy Using Advanced MRI

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-07

Start Date:

2021-04-08

Completion:

2028-12-31

Conditions

• Meningioma

Interventions

• OTHER

No Results Yet

NCT04629248 | ACTIVE_NOT_RECRUITING | PHASE3

142 participants

A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-06-25

Completion:

2025-12-22

Conditions

• Primary Membranous Nephropathy

Interventions

• DRUG

No Results Yet

NCT04626882 | ACTIVE_NOT_RECRUITING | NA

994 participants

Timing of FFR-guided PCI for Non-IRA in STEMI and MVD (OPTION-STEMI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2019-12-30

Completion:

2025-01-15

Conditions

• Myocardial Infarction, Acute
• Multi-Vessel Coronary Artery Stenosis

Interventions

• PROCEDURE

No Results Yet

NCT04624256 | ACTIVE_NOT_RECRUITING | NA

208 participants

Germline DNA-Based Radiosensitivity Biomarker Influence on Toxicity Following Prostate Radiotherapy, GARUDA Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-11-10

Completion:

2027-12-31

Conditions

• Prostate Adenocarcinoma
• Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8
• Stage II Prostate Cancer AJCC v8
• Stage IIA Prostate Cancer AJCC v8
• Stage IIB Prostate Cancer AJCC v8
• Stage IIC Prostate Cancer AJCC v8

Interventions

• PROCEDURE
• RADIATION
• OTHER

No Results Yet

NCT04615273 | COMPLETED | PHASE3

264 participants

A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-12-03

Completion:

2023-11-02

Conditions

• Growth Hormone Deficiency
• Endocrine System Diseases
• Hormone Deficiency

Interventions

• DRUG
• OTHER

Results Available

NCT04610866 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

15 participants

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-12-09

Completion:

2028-02-28

Conditions

• Sickle Cell Disease
• Hemolytic Anemia

Interventions

• DRUG

No Results Yet

NCT04600115 | RECRUITING | EARLY_PHASE1

100 participants

New MRI Methods Applied to Heart Failure With Preserved Ejection Fraction (HFpEF)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2017-03-03

Completion:

2027-03-03

Conditions

• MRI Scans

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04585477 | SUSPENDED | PHASE2

80 participants

Adjuvant ctDNA-Adapted Personalized Treatment in Early Stage NSCLC (ADAPT-E)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-04-08

Completion:

2026-12-30

Conditions

• Non-small Cell Lung Cancer
• Non-small Cell Lung Cancer Stage I
• Non-small Cell Lung Cancer Stage II
• Non-small Cell Lung Cancer Stage III

Interventions

• DEVICE
• DRUG

No Results Yet

NCT04580017 | COMPLETED

4267 participants

Prognostic Accuracy of the HEART Score in Undifferentiated Chest Pain: A Multicenter Validation Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-07

Start Date:

2015-01-31

Completion:

2017-04-30

Conditions

• Coronary Disease
• Coronary Syndrome
• Risk Factor, Cardiovascular
• Major Adverse Cardiovascular Events

No Results Yet

NCT04524000 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

Study Assessing the Efficacy and Safety of Treatment With Alpelisib Plus Fulvestrant in Japanese Men and Postmenopausal Women With Advanced Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-01-08

Completion:

2027-02-26

Conditions

• Advanced Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04515901 | WITHDRAWN | NA

0 participants

Spenopalatine Ganglion Block for Treatment of Post-dural Puncture Headaches

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-12-01

Completion:

2022-11-11

Conditions

• Postdural Puncture Headache

Interventions

• DRUG
• OTHER

No Results Yet

NCT04464226 | ACTIVE_NOT_RECRUITING | PHASE3

402 participants

Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-10-20

Completion:

2028-06-26

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT04447768 | ACTIVE_NOT_RECRUITING | PHASE2

100 participants

The Combination of Venetoclax and Obinutuzumab in People With Chronic Lymphocytic Leukemia (CLL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-12-03

Completion:

2027-07-31

Conditions

• Chronic Lymphocytic Leukemia (CLL)

Interventions

• DRUG

No Results Yet

NCT04439708 | RECRUITING

250 participants

Biomarkers and Choroidal Neovascularization

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-07

Start Date:

2020-07-06

Completion:

2027-01-06

Conditions

• Choroidal Neovascularization
• Mineralocorticoid Excess

Interventions

• OTHER

No Results Yet

NCT04437654 | COMPLETED | PHASE4

1803 participants

The Efficacy and Safety of Non-vItamiN K antaGonist oraL Anticoagulants for intermEdiate Stroke Risk in Patients With Atrial Fibrillation (SINGLE-AF)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-07-28

Completion:

2025-08-21

Conditions

• Atrial Fibrillation Patients With Intermediate Stroke Risk

Interventions

• DRUG

No Results Yet

NCT04431726 | ACTIVE_NOT_RECRUITING | PHASE3

55 participants

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-02-04

Completion:

2023-05-22

Conditions

• Severe Hemophilia A

Interventions

• DRUG

Results Available

NCT04408638 | ACTIVE_NOT_RECRUITING | PHASE3

270 participants

A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2021-02-23

Completion:

2028-03-31

Conditions

• Diffuse Large B-cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT04406662 | RECRUITING

600 participants

Routine Evaluation of People Living With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-07

Start Date:

2020-07-15

Completion:

2029-08-08

Conditions

• Cachexia; Cancer
• Advanced Cancer
• Quality of Life

No Results Yet

NCT04403230 | ACTIVE_NOT_RECRUITING | NA

52 participants

Outcomes on Teeth Prepared With BOPT

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2013-01-01

Completion:

2014-01-01

Conditions

• Soft Tissues
• Prosthetic
• Outcome

Interventions

• PROCEDURE

No Results Yet

NCT04400292 | ACTIVE_NOT_RECRUITING | NA

90 participants

Sentinel Lymph Node Mapping in Esophageal Cancer Using ICG Dye and NIR Imaging

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-05-20

Completion:

2027-05-31

Conditions

• Esophageal Cancer

Interventions

• OTHER
• DEVICE
• PROCEDURE

No Results Yet

NCT04375605 | COMPLETED | PHASE3

342 participants

Neoadjuvant RCT Versus CT for Patients With Locally Advanced, Potentially Resectable Adenocarcinoma of the GEJ

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-06-03

Completion:

2026-06-30

Conditions

• Gastroesophageal Junction Adenocarcinoma

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04324411 | WITHDRAWN | PHASE4

0 participants

Sirolimus Combined With ATRA for the Treatment of Auto-Immune Anemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-04-20

Completion:

2023-05-01

Conditions

• Autoimmune Anemia

Interventions

• DRUG

No Results Yet

NCT04315571 | COMPLETED | NA

68 participants

Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion Stents

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-03-24

Completion:

2026-04-01

Conditions

• Hypertension, Portal
• Ascites

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT04297020 | RECRUITING

120 participants

Brain Health in Breast Cancer Survivors

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-07

Start Date:

2020-03-11

Completion:

2027-03-15

Conditions

• Cognitive Impairment
• Cognitive Function

No Results Yet

NCT04283513 | SUSPENDED | PHASE2

50 participants

Treatment of Hemorrhagic Fever With Ribavirin

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2022-10-31

Completion:

2027-04-30

Conditions

• Hemorrhagic Fever

Interventions

• DRUG

No Results Yet

NCT04260958 | ACTIVE_NOT_RECRUITING | NA

1500 participants

Remote Exercise SWEDEHEART Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-07

Start Date:

2020-02-03

Completion:

2025-06-01

Conditions

• Myocardial Infarction

Interventions

• OTHER

No Results Yet