Clinical Trials

NCT05131022 | RECRUITING | PHASE1

572 participants

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2022-04-13

Completion:

2027-01-31

Conditions

• Chronic Lymphocytic Leukemia (CLL)
• Small Lymphocytic Lymphoma (SLL)
• Diffuse Large B Cell Lymphoma (DLBCL)
• Follicular Lymphoma (FL)
• Mantle Cell Lymphoma (MCL)
• Marginal Zone Lymphoma (MZL)
• Waldenstrom Macroglobulinemia (WM)
• Primary Central Nervous System Lymphoma (PCNSL)
• Secondary Central Nervous System Lymphoma (SCNSL)

Interventions

• DRUG

No Results Yet

NCT05078229 | COMPLETED | NA

505 participants

Evaluating Stress Management Among Allogeneic HCT Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-09-16

Completion:

2026-03-31

Conditions

• Burden
• Stress

Interventions

• BEHAVIORAL

No Results Yet

NCT05070403 | ACTIVE_NOT_RECRUITING | PHASE2

35 participants

Study of Afatinib in Advanced Cutaneous Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-10-01

Completion:

2027-02-28

Conditions

• Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT05064085 | COMPLETED | PHASE1

13 participants

Capecitabine In Combination With Cemiplimab In Patient With Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-10-12

Completion:

2024-09-09

Conditions

• Hormone Receptor-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05047250 | ACTIVE_NOT_RECRUITING | PHASE3

60 participants

A Study of Atezolizumab in High PD-L1 Expression, Chemotherapy-Naïve Patients With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2022-06-14

Completion:

2025-12-30

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05036486 | ACTIVE_NOT_RECRUITING

480 participants

The Registry of Genetic Alterations of Taiwan Biliary Tract Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2021-10-25

Completion:

2030-12-31

Conditions

• Biliary Tract Cancer (BTC)

Interventions

• GENETIC

No Results Yet

NCT05026905 | ACTIVE_NOT_RECRUITING | PHASE2

66 participants

A Phase II Randomized Study of Gemcitabine and Nab-paclitaxel in Combination With S- 1/LV (GASL) or Oxaliplatin (GAP) as First-line Treatment for Metastatic Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-12-28

Completion:

2027-12-31

Conditions

• Phase II, Open-label, Parallel 2-arm, Multi-center

Interventions

• DRUG

No Results Yet

NCT05022459 | RECRUITING

72 participants

Prevention of Bleeding in Patients With Moderate and Severe Hemophilia A Playing Sports: A Comparison Between Factor VIII and Emicizumab Prophylaxis

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2023-08-16

Completion:

2029-01-31

Conditions

• Hemophilia A

Interventions

• DRUG

No Results Yet

NCT04989946 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

57 participants

Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-12-16

Completion:

2026-12-31

Conditions

• Prostate Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04979429 | COMPLETED | NA

401 participants

The Perioperative Pain Self-Management Program Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-08-03

Completion:

2026-06-15

Conditions

• Postoperative Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT04944576 | ACTIVE_NOT_RECRUITING

82 participants

Observational Study to Evaluate Safety and Performance of the Total Ankle Prosthesis, EasyMove®

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2021-09-14

Completion:

2029-09-13

Conditions

• Ankle Injuries and Disorders

Interventions

• DEVICE

No Results Yet

NCT04942717 | RECRUITING | NA

234 participants

Adapting for Latinx Populations an Intervention That Involves Discussing and Sharing Patients' Health-Related Values

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-06-18

Completion:

2027-06-18

Conditions

• Solid Tumor
• Solid Tumor, Adult
• Solid Tumor, Unspecified, Adult

Interventions

• BEHAVIORAL

No Results Yet

NCT04925089 | RECRUITING

40 participants

Localized Leiomyosarcoma Biomarker Protocol

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2023-04-26

Completion:

2026-11-30

Conditions

• Leiomyosarcoma

Interventions

• OTHER

No Results Yet

NCT04895722 | ACTIVE_NOT_RECRUITING | PHASE2

302 participants

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-06-25

Completion:

2025-05-21

Conditions

• Colorectal Cancer

Interventions

• BIOLOGICAL

Results Available

NCT04876339 | RECRUITING | NA

120 participants

Sonification Techniques for Gait Training

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-01-18

Completion:

2026-12-31

Conditions

• Parkinson Disease
• Stroke
• Multiple Sclerosis

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04873245 | COMPLETED | PHASE2

120 participants

Lifestyle Counseling and Medication for Adolescent Weight Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2022-03-15

Completion:

2026-06-29

Conditions

• Obesity, Childhood

Interventions

• BEHAVIORAL
• DRUG

No Results Yet

NCT04864158 | RECRUITING | NA

102 participants

Prosthesis Versus Active Exercise Program in Patients With Rotator Cuff Arthropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-05-28

Completion:

2027-01-31

Conditions

• Rotator Cuff Arthropathy

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04851470 | RECRUITING

394 participants

Periodontal Assessment of a Bariatric Care Population

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2014-01-31

Completion:

2027-12-31

Conditions

• Bariatric Surgery Candidate
• Obesity

No Results Yet

NCT04850599 | ACTIVE_NOT_RECRUITING | PHASE2

5 participants

Isatuximab, Carfilzomib, and Pomalidomide for the Treatment of Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2022-06-14

Completion:

2027-10-15

Conditions

• Recurrent Plasma Cell Myeloma
• Refractory Plasma Cell Myeloma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04850495 | ACTIVE_NOT_RECRUITING | PHASE1

38 participants

Zanubrutinib in Combination With R-PolaCHP (ZaR-PolaCHP) for Newly Diagnosed Diffuse Large B-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-11-16

Completion:

2026-06-23

Conditions

• Diffuse Large B-Cell Lymphoma
• Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
• Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04849728 | ACTIVE_NOT_RECRUITING | PHASE3

1000 participants

A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-08-19

Completion:

2027-09-30

Conditions

• NASH - Nonalcoholic Steatohepatitis

Interventions

• DRUG

No Results Yet

NCT04845074 | COMPLETED | NA

102 participants

Prosthesis Versus Active Exercise Program in Patients With Glenohumeral Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-06-02

Completion:

2026-05-26

Conditions

• Glenohumeral Osteoarthritis

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04821895 | ACTIVE_NOT_RECRUITING

50 participants

Oncogenetic Panel and Integrated Clinical Data Registry Study for Wild Type Gastrointestinal Stromal Tumor Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2021-08-28

Completion:

2029-12-31

Conditions

• Gastrointestinal Stromal Tumor (GIST)

No Results Yet

NCT04819841 | RECRUITING | PHASE1/PHASE2

15 participants

Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-11-15

Completion:

2026-12-31

Conditions

• Sickle Cell Disease

Interventions

• GENETIC

No Results Yet

NCT04817774 | COMPLETED | PHASE1/PHASE2

26 participants

Safety & Tolerability Study of Chimeric Antigen Receptor T-Reg Cell Therapy in Living Donor Renal Transplant Recipients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-03-17

Completion:

2024-07-11

Conditions

• Kidney Transplant Rejection
• End Stage Renal Disease

Interventions

• BIOLOGICAL

Results Available

NCT04809766 | TERMINATED | PHASE1

9 participants

Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-12-14

Completion:

2024-10-24

Conditions

• Metastatic Pancreatic Ductal Adenocarcinoma
• Stage IV Pancreatic Cancer AJCC v8

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04805242 | COMPLETED | NA

60 participants

Effects of Dextrose Prolotherapy in Rotator Cuff Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-03-18

Completion:

2021-10-12

Conditions

• Rotator Cuff Disease

Interventions

• OTHER

No Results Yet

NCT04787367 | COMPLETED | NA

200 participants

Laparoscopic TAP Block for Sleeve Gastrectomy: Does Timing Matter

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2019-02-12

Completion:

2022-07-01

Conditions

• Obesity
• Pain, Postoperative

Interventions

• PROCEDURE

Results Available

NCT04782830 | RECRUITING | NA

29 participants

Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-02-05

Completion:

2027-06-01

Conditions

• Multiple System Atrophy
• Orthostatic; Hypotension, Neurogenic
• Autonomic Failure
• Pure Autonomic Failure
• Orthostatic; Hypotension, Parkinsonism

Interventions

• DEVICE
• DRUG

No Results Yet

NCT04775550 | ACTIVE_NOT_RECRUITING | PHASE2

61 participants

DARA RVD For High Risk SMM

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-03-08

Completion:

2027-12-20

Conditions

• High-risk Smoldering Multiple Myeloma
• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT04724369 | ACTIVE_NOT_RECRUITING | PHASE3

43 participants

Open-Label Study of 18F-mFBG for Imaging Neuroblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-11-18

Completion:

2026-07-30

Conditions

• Neuroblastoma

Interventions

• DRUG

No Results Yet

NCT04724330 | COMPLETED | NA

534 participants

Pragmatic Randomized Clinical Trial to Limit Weight Gain in Pregnancy and Prevent Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-03-15

Completion:

2025-01-31

Conditions

• Pregnancy Weight Gain
• Postpartum Weight Retention
• Childhood Obesity
• Gestational Diabetes
• Overweight and Obesity

Interventions

• BEHAVIORAL

Results Available

NCT04645602 | RECRUITING | PHASE2

20 participants

Merck IIT: RRP Pembro and Lenvatinib

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2025-07-18

Completion:

2027-12-31

Conditions

• Human Papilloma Virus
• Recurrent Respiratory Papillomatosis
• Pulmonary Disease

Interventions

• DRUG

No Results Yet

NCT04626635 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

548 participants

A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-12-21

Completion:

2026-11-13

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04621396 | RECRUITING

600 participants

The Next Generation Longitudinal Birth Cohort Diabetes Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-02

Start Date:

2013-09-30

Completion:

2026-12-31

Conditions

• Type 2 Diabetes
• Gestational Diabetes Mellitus

Interventions

• OTHER

No Results Yet

NCT04609904 | COMPLETED | PHASE3

2187 participants

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-03-01

Completion:

2025-03-20

Conditions

• Asthma

Interventions

• DRUG

Results Available

NCT04595825 | COMPLETED | PHASE2

77 participants

CM-101 in PSC Patients -The SPRING Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-10-01

Completion:

2025-01-10

Conditions

• Primary Sclerosing Cholangitis

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04576117 | ACTIVE_NOT_RECRUITING | PHASE3

300 participants

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-02-16

Completion:

2026-12-30

Conditions

• Recurrent Low Grade Astrocytoma
• Recurrent WHO Grade 2 Glioma
• Refractory Low Grade Astrocytoma
• Refractory Low Grade Glioma
• Refractory WHO Grade 1 Glioma

Interventions

• PROCEDURE
• OTHER
• DRUG

No Results Yet

NCT04562870 | ACTIVE_NOT_RECRUITING | PHASE2

112 participants

A Study to Evaluate Single Agent Selinexor Versus Physician's Choice in Participants With Previously Treated Myelofibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2021-03-17

Completion:

2026-09-30

Conditions

• Myelofibrosis

Interventions

• OTHER
• DRUG

No Results Yet

NCT04541446 | COMPLETED | NA

773 participants

Study Dynamic Haptic Robotic Trainer (DHRT) and DHRT+ for Central Venous Catherization Insertion Training for Surgical Residents

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-02

Start Date:

2020-08-19

Completion:

2025-06-30

Conditions

• Central Line Complication
• Central Line Infection

Interventions

• OTHER

No Results Yet