Clinical Trials

NCT05535868 | COMPLETED | NA

91 participants

Experimental Human Pneumococcal Challenge With SPN3

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-08-01

Completion:

2023-11-21

Conditions

• Streptococcus Pneumonia
• Controlled Human Infection

Interventions

• OTHER

Results Available

NCT05520099 | ACTIVE_NOT_RECRUITING

416 participants

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-02)

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2023-06-26

Completion:

2027-01-31

Conditions

• Immunotherapy
• Cancer
• Bladder Cancer
• Urothelial Carcinoma Bladder
• Kidney Cancer
• Clear Cell Renal Cell Cancer (ccRCC)
• Colorectal Cancer
• MSI-H Colorectal Cancer
• DMMR Colorectal Cancer
• Head and Neck Cancer (H&N)
• Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)
• Liver Cancer
• Hepatocellular Carcinoma (HCC)
• Lung Cancer (NSCLC)
• NSCLC (Non-small Cell Lung Cancer)
• Skin Cancer
• Cutaneous Melanoma
• Endometrial Cancer
• Solid Tumor Cancer

Interventions

• PROCEDURE

No Results Yet

NCT05516628 | RECRUITING | PHASE2

30 participants

Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2023-02-28

Completion:

2027-03-31

Conditions

• Hepatocellular Carcinoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05508464 | RECRUITING | NA

138 participants

Ablative Radiotherapy to Restrain Every Metastasis Safely Treatable (ARREST-2): A Randomized Phase II/III Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2023-10-16

Completion:

2034-01-01

Conditions

• Metastatic Cancer

Interventions

• RADIATION

No Results Yet

NCT05501236 | RECRUITING | NA

100 participants

Ansa Cervicalis and Hypoglossal Nerve Stimulation in OSA

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-11-03

Completion:

2027-05-30

Conditions

• Obstructive Sleep Apnea

Interventions

• DEVICE

No Results Yet

NCT05499091 | RECRUITING | NA

1200 participants

Functional Study to Indentify Genetic Etiology of Rare Diseases - ORIGIN

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-10-10

Completion:

2042-10-10

Conditions

• Rare Diseases
• Genetic Disease

Interventions

• PROCEDURE

No Results Yet

NCT05478720 | RECRUITING | PHASE1/PHASE2

152 participants

DON in Pediatric Cerebral Malaria

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-08-16

Completion:

2026-12-31

Conditions

• Malaria, Cerebral

Interventions

• DRUG

No Results Yet

NCT05478538 | ACTIVE_NOT_RECRUITING

200 participants

Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform (ELEPHAS-01)

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2023-01-31

Completion:

2026-12-31

Conditions

• NSCLC (Non-small Cell Lung Cancer)
• Metastatic NSCLC - Non-Small Cell Lung Cancer

Interventions

• PROCEDURE

No Results Yet

NCT05453513 | RECRUITING | NA

280 participants

The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-04-01

Completion:

2027-07-30

Conditions

• Depression
• Cannabis Use Disorder
• HIV

Interventions

• BEHAVIORAL

No Results Yet

NCT05452772 | RECRUITING | PHASE2

66 participants

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2023-11-01

Completion:

2026-12-31

Conditions

• Tobacco Use Disorder

Interventions

• DRUG

No Results Yet

NCT05438719 | ACTIVE_NOT_RECRUITING | NA

158 participants

MOTUS Total Joint Replacement Investigational Device Exemption Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-06-23

Completion:

2026-02-09

Conditions

• Lumbar Spine Degeneration

Interventions

• DEVICE

No Results Yet

NCT05438511 | RECRUITING

85 participants

A Formative Evaluation For Improving Breast Cancer Hormone Receptor Testing in Tanzania

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2023-04-13

Completion:

2027-04-30

Conditions

• Breast Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05433688 | COMPLETED

150 participants

Study on the Performance of Symmcora® Mid-term Suture Versus Novosyn® Suture in Patients Undergoing Robotic Assisted Gastric Bypass Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2022-10-12

Completion:

2026-03-11

Conditions

• Adiposity

Interventions

• DEVICE

No Results Yet

NCT05415384 | RECRUITING | NA

80 participants

Randomized Control Trial, Cryoablation as an Adjunct to Surgical Stabilization of Rib Fractures

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-08-01

Completion:

2026-11-30

Conditions

• Pain, Postoperative
• Rib Fracture Multiple

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT05410509 | COMPLETED | NA

25 participants

"Embolization Before Ablation of Renal Cell Carcinoma (EMBARC)"

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2024-01-03

Completion:

2025-11-19

Conditions

• Renal Cell Carcinoma (RCC)

Interventions

• PROCEDURE

No Results Yet

NCT05408559 | WITHDRAWN | PHASE1/PHASE2

0 participants

Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol ES

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-07-01

Completion:

2025-09-30

Conditions

• Diastolic Dysfunction
• Systolic Dysfunction
• Diastolic Heart Failure

Interventions

• DRUG

No Results Yet

NCT05403047 | RECRUITING | PHASE4

150 participants

Efficacy of Tenofovir Disoproxil on Mother-to-child Transmission of HBV in Tokombéré, Cameroon in Pregnant Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2023-08-22

Completion:

2027-08-31

Conditions

• Hepatitis B Virus - Chronic Active

Interventions

• DRUG

No Results Yet

NCT05402384 | NOT_YET_RECRUITING | PHASE2

10 participants

AVTX-801 D-galactose Supplementation in SLC35A2-CDG

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2027-01-31

Completion:

2028-03-31

Conditions

• SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation

Interventions

• DRUG

No Results Yet

NCT05401175 | RECRUITING | NA

40 participants

Hematopoietic Stem Cell-containing Autologous Blood Reinfusion for Bone Marrow Protection in Cervical Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-04-13

Completion:

2027-04-30

Conditions

• Cervical Cancer

Interventions

• OTHER

No Results Yet

NCT05401162 | RECRUITING | NA

40 participants

Chemotherapy Supported by Autologous Hematopoietic Stem Cells

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-04-15

Completion:

2027-05-31

Conditions

• Ovarian Cancer

Interventions

• OTHER

No Results Yet

NCT05379101 | COMPLETED

81 participants

Intracardiac Flow Assessment in Cardiac Amyloidosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2022-07-20

Completion:

2026-05-31

Conditions

• Amyloidosis Cardiac
• Healthy Adults

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05377996 | RECRUITING | PHASE1/PHASE2

360 participants

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-08-15

Completion:

2027-02-28

Conditions

• Triple Negative Breast Cancer
• Breast Cancer
• Endometrial Cancer
• Ovarian Cancer
• Fallopian Tube Cancer
• Primary Peritoneal Cavity Cancer
• Adenoid Cystic Carcinoma

Interventions

• DRUG

No Results Yet

NCT05377242 | COMPLETED | NA

390 participants

Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2023-05-31

Completion:

2026-06-22

Conditions

• Gulf War Illness

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05376644 | COMPLETED | NA

15 participants

Molecular Imaging of HER2 Expression in HER2-positive Breast Cancer Using 99mTc-ADAPT6 vs 99mTc-DARPinG3

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-05-01

Completion:

2022-12-31

Conditions

• Breast Cancer Female

Interventions

• DRUG

No Results Yet

NCT05363488 | COMPLETED

17 participants

Retrospective Observational Research Study to Describe the Real World Use of Bosutinib in a Single Centre in Scotland

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2019-05-01

Completion:

2019-11-01

Conditions

• Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT05359861 | COMPLETED | PHASE2

30 participants

Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-04-12

Completion:

2025-06-30

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT05354505 | RECRUITING | NA

10 participants

Fetal Endoscopic Tracheal Occlusion (FETO) Trial for Congenital Diaphragmatic Hernia (CDH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2026-05-28

Completion:

2028-06-30

Conditions

• Diaphragmatic Hernia

Interventions

• DEVICE

No Results Yet

NCT05326464 | COMPLETED | PHASE3

18 participants

Tofacitinib in Recurrent GBM Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-10-07

Completion:

2025-02-18

Conditions

• Glioblastoma

Interventions

• DRUG

Results Available

NCT05325970 | COMPLETED

202 participants

Clinical Registry of Long-Term Dental Outcomes in Head and Neck Cancer Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2014-02-28

Completion:

2026-02-04

Conditions

• Head and Neck Cancer
• Dental Diseases
• Osteoradionecrosis

No Results Yet

NCT05318976 | COMPLETED | PHASE2

207 participants

A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-02-28

Completion:

2025-05-12

Conditions

• Alzheimer Disease
• Dementia
• Brain Diseases
• Central Nervous System Diseases
• Nervous System Diseases
• Tauopathies
• Neurodegenerative Diseases
• Neurocognitive Disorders
• Mental Disorders
• Mild Cognitive Impairment

Interventions

• DRUG

Results Available

NCT05301140 | RECRUITING

1000 participants

Vivistim Registry for Paired VNS Therapy (GRASP)

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2023-03-15

Completion:

2028-12-31

Conditions

• Upper Extremity Problem

Interventions

• DEVICE

No Results Yet

NCT05283564 | COMPLETED | NA

25 participants

Study to Evaluate Percussive Ventilation Breathhold to Improve Lung Stereotactic Ablative Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-11-02

Completion:

2025-10-28

Conditions

• Lung Cancer

Interventions

• OTHER

No Results Yet

NCT05276791 | RECRUITING | NA

331 participants

EMR Versus ESD for Barrett's Neoplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2023-01-17

Completion:

2027-12-01

Conditions

• Barretts Esophagus With Dysplasia
• Barrett Adenocarcinoma
• Esophageal Cancer

Interventions

• OTHER

No Results Yet

NCT05273723 | COMPLETED | PHASE1

42 participants

A BCT Intervention for Physical Activity Among Individuals on Statins

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-03-22

Completion:

2023-07-28

Conditions

• Insufficient Physical Activity

Interventions

• BEHAVIORAL

Results Available

NCT05271435 | COMPLETED

20 participants

Digital Tools for Assessment of Motor Functions and Falls in ALS

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2021-10-01

Completion:

2026-06-25

Conditions

• ALS
• PLS
• PMA

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT05265351 | COMPLETED | NA

50 participants

Ultrafast Ultrasound for the Functional Assessment of the Diaphragm

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2023-05-24

Completion:

2025-02-13

Conditions

• Diaphragm Dysfunction

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05204290 | TERMINATED | EARLY_PHASE1

1 participants

Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-03-28

Completion:

2022-10-07

Conditions

• Epidural Spinal Tumors
• Cancer

Interventions

• DRUG
• RADIATION
• OTHER

Results Available

NCT05197946 | RECRUITING

300 participants

Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2018-12-04

Completion:

2028-12-31

Conditions

• Cerebral Palsy
• Chronic Pain

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05179967 | COMPLETED | NA

106 participants

Safety and Efficacy Study of WeFlow-JAAA Stent Graft System for Complex Abdominal Aortic Aneurysm(GREAT Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-29

Start Date:

2022-02-23

Completion:

2025-06-17

Conditions

• Juxtarenal Abdominal Aortic Aneurysm

Interventions

• DEVICE

No Results Yet

NCT05164757 | ACTIVE_NOT_RECRUITING

1041 participants

Female Asian Nonsmoker Screening Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-29

Start Date:

2021-03-01

Completion:

2035-06-30

Conditions

• Lung Cancer

No Results Yet