Clinical Trials

NCT04536805 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

44 participants

Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-11-17

Completion:

2031-11-30

Conditions

• Prostate Cancer

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04522544 | ACTIVE_NOT_RECRUITING | PHASE2

55 participants

Durvalumab and Tremelimumab in Combination With Y-90 SIRT for Intermediate Stage HCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-12-15

Completion:

2027-07-31

Conditions

• Hepatocellular Carcinoma Non-resectable
• HCC

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04510636 | RECRUITING | PHASE2

40 participants

Study of Pembrolizumab With Bendamustine in Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-12-20

Completion:

2026-11-01

Conditions

• Classical Hodgkin Lymphoma
• Relapsed Cancer
• Refractory Cancer

Interventions

• DRUG

No Results Yet

NCT04456920 | COMPLETED | NA

193 participants

Pain Monitoring After Breast Biopsy: Benefit of E-health

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-02-09

Completion:

2023-11-20

Conditions

• Breast Cancer
• Biopsy Wound

Interventions

• OTHER

Results Available

NCT04414202 | ACTIVE_NOT_RECRUITING

519 participants

Observational Study of Intra-operative Partial Irradiation of Invasive Ductal Breast Carcinomas With a Good Prognosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2009-12-15

Completion:

2023-10-16

Conditions

• Invasive Breast Cancer
• Breast-conserving Surgery

Interventions

• PROCEDURE
• RADIATION

Results Available

NCT04353804 | ACTIVE_NOT_RECRUITING | NA

160 participants

Returning to Everyday Tasks Utilizing Rehabilitation Networks-III (RETURN-III)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-10-03

Completion:

2026-04-14

Conditions

• Cognitive Rehabilitation
• ICU Survivorship
• Intensive Care Unit
• ICU

Interventions

• OTHER

No Results Yet

NCT04346225 | SUSPENDED | PHASE2

75 participants

Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-07-16

Completion:

2026-12-31

Conditions

• Prostate Cancer
• Advanced Prostate Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04323722 | COMPLETED | NA

53 participants

Impact of Bladder Depletion on Mesorectal Movements During Radiotherapy in Rectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-09-08

Completion:

2024-09-11

Conditions

• Rectal Cancer

Interventions

• PROCEDURE

Results Available

NCT04318938 | COMPLETED | PHASE2

118 participants

Advancing Brigatinib Properties in ALK+ NSCLC Patients by Deep Phenotyping

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-03-30

Completion:

2026-05-30

Conditions

• NSCLC

Interventions

• DRUG

No Results Yet

NCT04282395 | ACTIVE_NOT_RECRUITING | NA

284 participants

Resilience-Based Diabetes Self-Management Education (RB-DSME) for African Americans

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-01-25

Completion:

2025-04-26

Conditions

• Type 2 Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT04277546 | TERMINATED | PHASE2

57 participants

Open-label Extension Study of Brazikumab in Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-03-03

Completion:

2023-10-10

Conditions

• Ulcerative Colitis

Interventions

• DRUG

Results Available

NCT04252508 | COMPLETED | NA

80 participants

Impact of a Double-reading Animated Film (Child, Parents) in Preoperative on the Anxiety of Children Upon Arrival at the Operating Room

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-10-09

Completion:

2022-05-02

Conditions

• Anxiety
• Surgery
• Pediatric ALL

Interventions

• OTHER

No Results Yet

NCT04225039 | ACTIVE_NOT_RECRUITING | PHASE2

39 participants

Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-06-23

Completion:

2022-09-08

Conditions

• Glioblastoma

Interventions

• DRUG
• PROCEDURE

Results Available

NCT04185363 | COMPLETED | PHASE3

84 participants

An Extension Study of Maralixibat in Patients With Progressive Familial Intrahepatic Cholestasis (PFIC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-01-08

Completion:

2025-04-23

Conditions

• Progressive Familial Intrahepatic Cholestasis (PFIC)

Interventions

• DRUG

Results Available

NCT04154891 | COMPLETED | NA

3825 participants

Genome Sequencing Strategies for Genetics Diagnosis of Patients With Intellectual Disability

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-03-13

Completion:

2023-12-31

Conditions

• Intellectual Disability

Interventions

• GENETIC

No Results Yet

NCT04150640 | RECRUITING | PHASE2

52 participants

Oxaliplatin and Liposomal Irinotecan (Plus Trastuzumab for HER2-positive Disease) in Advanced Esophageal and Gastric Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-07-13

Completion:

2027-12-31

Conditions

• Esophageal Adenocarcinoma
• Gastric Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT04134754 | RECRUITING | NA

335 participants

Carbon Dioxide (CO2) Chemosensitivity and SUDEP

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-12-12

Completion:

2029-10-01

Conditions

• Epilepsy
• SUDEP

Interventions

• OTHER

No Results Yet

NCT04123366 | COMPLETED | PHASE2

333 participants

Study of Olaparib (MK-7339) in Combination With Pembrolizumab (MK-3475) in the Treatment of Homologous Recombination Repair Mutation (HRRm) and/or Homologous Recombination Deficiency (HRD)-Positive Advanced Cancer (MK-7339-007/KEYLYNK-007)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-11-18

Completion:

2026-06-08

Conditions

• Solid Tumors

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04114136 | RECRUITING | PHASE2

72 participants

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-09-14

Completion:

2032-04-30

Conditions

• Melanoma
• NSCLC
• Hepatocellular Carcinoma
• Urothelial Cancer
• Gastric Adenocarcinoma
• HNSCC
• Esophageal Adenocarcinoma
• Microsatellite Instability-High Solid Malignant Tumor

Interventions

• DRUG

No Results Yet

NCT04113187 | TERMINATED | PHASE3

15 participants

Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-06-23

Completion:

2022-05-19

Conditions

• Hereditary Hemorrhagic Telangiectasia
• Osler Weber Rendu Disease

Interventions

• DRUG

No Results Yet

NCT04111770 | COMPLETED | NA

806 participants

The OPTIMAL Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-07-08

Completion:

2025-07-31

Conditions

• Left Main Coronary Artery Stenosis

Interventions

• DEVICE

No Results Yet

NCT04096170 | COMPLETED | PHASE4

16 participants

Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-06-21

Completion:

2024-04-24

Conditions

• Hernia, Paraesophageal

Interventions

• DRUG

Results Available

NCT04084717 | COMPLETED | PHASE2

33 participants

Study of Crizotinib for ROS1 and MET Activated Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-12-03

Completion:

2024-12-30

Conditions

• Non-squamous Non-small-cell Lung Cancer
• Stage IV Non-small Cell Lung Cancer
• ROS1 Gene Rearrangement
• MET Activating Mutation
• MET Amplification

Interventions

• DRUG

No Results Yet

NCT04067973 | COMPLETED

88 participants

Impact of Prematurity on the Optic Nerve

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2019-09-09

Completion:

2019-12-10

Conditions

• Ocular Surface Disease
• Premature

No Results Yet

NCT04067908 | TERMINATED | NA

111 participants

New Biomarkers Associated With the Risk of Premature Delivery.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2011-06-07

Completion:

2013-12-28

Conditions

• Premature Delivery

Interventions

• OTHER

No Results Yet

NCT04056117 | COMPLETED | PHASE1/PHASE2

597 participants

A Study to Determine If a New Shigella Vaccine is Safe, Induces Immunity and The Best Dose Among Kenyan Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-09-02

Completion:

2022-09-01

Conditions

• Shigellosis

Interventions

• BIOLOGICAL

No Results Yet

NCT04021719 | SUSPENDED

2100 participants

OnTrackNY's Learning Healthcare System

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2019-08-15

Completion:

2026-12-30

Conditions

• First Episode Psychosis

Interventions

• OTHER

No Results Yet

NCT03991832 | ACTIVE_NOT_RECRUITING | PHASE2

58 participants

Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-12-31

Completion:

2026-09-30

Conditions

• Glioma
• Cholangiocarcinoma
• Solid Tumor
• IDH Mutation

Interventions

• DRUG

No Results Yet

NCT03991819 | ACTIVE_NOT_RECRUITING | PHASE1

40 participants

Study of Binimetinib in Combination With Pembrolizumab in Advanced Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-09-20

Completion:

2026-08-31

Conditions

• Non-small Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT03901963 | COMPLETED | PHASE3

200 participants

A Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Participants With Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-04-26

Completion:

2024-04-04

Conditions

• Multiple Myeloma

Interventions

• DRUG

Results Available

NCT03896620 | ACTIVE_NOT_RECRUITING

45 participants

Recognition of Circulating Tumor DNA in Soft Tissue Sarcoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2019-06-18

Completion:

2027-04-01

Conditions

• Sarcoma

Interventions

• DEVICE
• DRUG
• OTHER

No Results Yet

NCT03872947 | ACTIVE_NOT_RECRUITING | PHASE1

138 participants

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-04-26

Completion:

2026-06-30

Conditions

• Melanoma
• Solid Tumor
• Colorectal Cancer
• Cholangiocarcinoma
• Bladder Cancer
• Ovarian Cancer
• Gastric Cancer
• Palpable Subcutaneous Malignant Lesions
• Renal Cell Carcinoma
• Epithelial Ovarian Cancer
• Primary Peritoneal Cancer
• Fallopian Tube Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03872180 | ACTIVE_NOT_RECRUITING | PHASE2

23 participants

Bendamustine, Obinutuzumab, and Venetoclax in Patients With Untreated Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-04-11

Completion:

2022-06-06

Conditions

• CCND1 Positive
• Mantle Cell Lymphoma
• t(11;14) Positive

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT03818412 | RECRUITING | NA

40 participants

Circulating Tumor DNA in Soft Tissue Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-01-17

Completion:

2026-12-17

Conditions

• Soft Tissue Sarcoma

Interventions

• PROCEDURE

No Results Yet

NCT03810612 | ACTIVE_NOT_RECRUITING

3417 participants

Patient-reported Outcomes After Percutaneous Coronary Intervention

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2017-06-12

Completion:

2030-05-31

Conditions

• Coronary Artery Disease

No Results Yet

NCT03810599 | ACTIVE_NOT_RECRUITING | NA

870 participants

Patient-reported Outcomes in the Bergen Early Cardiac Rehabilitation Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2013-09-09

Completion:

2019-06-27

Conditions

• Coronary Artery Disease

Interventions

• OTHER

No Results Yet

NCT03808922 | RECRUITING | PHASE3

274 participants

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-05-23

Completion:

2028-09-01

Conditions

• Lower Respiratory Tract Infection
• Parainfluenza
• Immunocompromised
• COVID-19

Interventions

• DRUG

No Results Yet

NCT03776513 | TERMINATED | NA

30 participants

Neuro-cognitive Impact of Juvenile Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-12-12

Completion:

2020-02-19

Conditions

• Pediatric Obesity
• Behavior and Behavior Mechanisms
• Emotions

Interventions

• BEHAVIORAL

No Results Yet

NCT03759288 | TERMINATED | PHASE2/PHASE3

89 participants

An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-12-07

Completion:

2023-10-18

Conditions

• Crohn's Disease
• IBD

Interventions

• DRUG

Results Available

NCT03752775 | RECRUITING | NA

45 participants

Exoneuromusculoskeleton for Upper Limb Rehabilitation After Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-11-01

Completion:

2027-12-31

Conditions

• Upper Limb Rehabilitation

Interventions

• DEVICE

No Results Yet