Clinical Trials

NCT05042102 | RECRUITING | PHASE2

160 participants

Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-08-08

Completion:

2026-10-31

Conditions

• Alcohol Use Disorder

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT05033028 | RECRUITING | PHASE3

225 participants

Smartphones for Opiate Addiction Recovery

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-11-01

Completion:

2027-06-01

Conditions

• Opioid-use Disorder

Interventions

• OTHER

No Results Yet

NCT05031780 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

286 participants

A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-02-11

Completion:

2025-10-30

Conditions

• Sickle Cell Disease

Interventions

• DRUG
• OTHER

No Results Yet

NCT05024773 | ACTIVE_NOT_RECRUITING | PHASE3

130 participants

Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-12-29

Completion:

2028-05-31

Conditions

• Bladder Carcinoma in Situ (CIS)

Interventions

• DRUG

No Results Yet

NCT05015478 | COMPLETED | NA

52 participants

Rhythmic Light Therapy for Alzheimer's Disease Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-01-10

Completion:

2023-09-12

Conditions

• Mild Cognitive Impairment

Interventions

• DEVICE

Results Available

NCT05005403 | RECRUITING | PHASE1

694 participants

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-11-01

Completion:

2027-07-31

Conditions

• Non-Small Cell Lung Cancer
• Head and Neck Squamous Cell Carcinoma
• Micro Satellite Stable Colorectal Cancer
• Gastric/Esophageal Cancer
• High-Grade Serous Ovarian Cancer
• Pancreatic Cancer
• Triple Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04947254 | RECRUITING | PHASE2

200 participants

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-08-05

Completion:

2028-06-07

Conditions

• Prostate Carcinoma
• Stage IIC Prostate Cancer AJCC v8
• Stage III Prostate Cancer AJCC v8
• Stage IIIA Prostate Cancer AJCC v8
• Stage IIIB Prostate Cancer AJCC v8
• Stage IIIC Prostate Cancer AJCC v8
• Stage IVA Prostate Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• RADIATION

No Results Yet

NCT04942028 | COMPLETED | NA

161 participants

Exposure Therapy vs. Standardized Education for Distress Related to Somatic Symptoms

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-10-07

Completion:

2025-01-02

Conditions

• Somatic Symptom and Related Disorders
• Medically Unexplained Symptoms
• Psychological Factors Affecting Other Medical Conditions

Interventions

• BEHAVIORAL

No Results Yet

NCT04931771 | COMPLETED | NA

2235 participants

Fractional Flow Reserve or 3D-Quantitative-Coronary-Angiography Based Vessel-FFR Guided Revascularization

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-11-09

Completion:

2025-12-17

Conditions

• Coronary Artery Disease

Interventions

• DEVICE

No Results Yet

NCT04929392 | ACTIVE_NOT_RECRUITING | PHASE2

3 participants

Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-01-25

Completion:

2022-12-09

Conditions

• Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Esophageal Adenocarcinoma
• Esophageal Squamous Cell Carcinoma
• Pathologic Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8

Interventions

• DRUG
• PROCEDURE
• RADIATION
• BIOLOGICAL

Results Available

NCT04919512 | COMPLETED | PHASE2

163 participants

A Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-07-07

Completion:

2025-02-04

Conditions

• Urinary Bladder Neoplasms

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04901455 | COMPLETED | EARLY_PHASE1

24 participants

Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-10-03

Completion:

2026-02-16

Conditions

• COPD

Interventions

• BIOLOGICAL

No Results Yet

NCT04891068 | RECRUITING | PHASE2

40 participants

BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-01-10

Completion:

2027-05-31

Conditions

• Breast Cancer Invasive
• Early-stage Breast Cancer
• High Risk Breast Carcinoma

Interventions

• DRUG

No Results Yet

NCT04882007 | COMPLETED | PHASE2

136 participants

Study of OSE-127 vs Placebo in Patients With Moderate to Severe Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-10-02

Completion:

2024-04-30

Conditions

• Ulcerative Colitis

Interventions

• DRUG

Results Available

NCT04869111 | RECRUITING | NA

100000 participants

The BrainHealth Project

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-08-01

Completion:

2038-08-01

Conditions

• Healthy

Interventions

• BEHAVIORAL

No Results Yet

NCT04854070 | COMPLETED | NA

2020 participants

Intravascular Ultrasound Guidance for Complex High-risk Indicated Procedures

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-11-02

Completion:

2025-08-25

Conditions

• Complex Coronary Lesions

Interventions

• DEVICE

No Results Yet

NCT04839354 | COMPLETED | PHASE3

271 participants

Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-06-21

Completion:

2024-07-11

Conditions

• Sickle Cell Disease

Interventions

• DRUG
• OTHER

Results Available

NCT04764175 | ACTIVE_NOT_RECRUITING | NA

500 participants

Telephone All Nations Breath of Life

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-05-13

Completion:

2026-07-31

Conditions

• Smoking Cessation

Interventions

• BEHAVIORAL

No Results Yet

NCT04736030 | COMPLETED | NA

158 participants

Conmigo: A Mother-daughter Intervention to Promote Physical Activity

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-02-11

Completion:

2023-01-24

Conditions

• Exercise
• Women
• Hispanic Americans
• Child

Interventions

• BEHAVIORAL

Results Available

NCT04734704 | TERMINATED | NA

57 participants

Defining the Role of the Skin Microbiome in Immune-related Adverse Events

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-01-11

Completion:

2024-01-23

Conditions

• Vitiligo
• Skin Melanoma

Interventions

• PROCEDURE

No Results Yet

NCT04693949 | RECRUITING | NA

80 participants

Effect of Nano-structured Alumina Coating on the Bond Strength of Zirconia Resin-bonded Fixed Dental Prostheses

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2018-01-03

Completion:

2027-01-01

Conditions

• Missing Incisors
• Zirconia Surface Pretreatment
• Children
• Adults
• Debonding

Interventions

• OTHER

No Results Yet

NCT04678648 | RECRUITING | PHASE1

134 participants

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-03-03

Completion:

2026-12-15

Conditions

• Advanced Malignant Solid Neoplasm
• RAS Mutation
• Lung Cancer
• Colon Cancer
• Glioblastoma
• Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT04678297 | COMPLETED | NA

204 participants

Physical Activity Interventions To Heal Chronic Low Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-10-01

Completion:

2025-06-30

Conditions

• Chronic Low Back Pain

Interventions

• BEHAVIORAL

Results Available

NCT04669288 | TERMINATED | PHASE3

840 participants

AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-11-22

Completion:

2024-12-10

Conditions

• Asthma
• Wheezing

Interventions

• DRUG

Results Available

NCT04652518 | TERMINATED | PHASE2

185 participants

LYT-100 in Post-acute COVID-19 Respiratory Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-12-11

Completion:

2022-06-28

Conditions

• Covid19
• Post-acute COVID-19 Respiratory Disease

Interventions

• DRUG
• OTHER

Results Available

NCT04645355 | COMPLETED | PHASE4

17 participants

Guselkumab Immunogenetics

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-03-01

Completion:

2025-04-04

Conditions

• Psoriasis Guttate
• Plaque Psoriasis

Interventions

• DRUG

Results Available

NCT04615819 | ACTIVE_NOT_RECRUITING | NA

376 participants

Access to Kidney Transplantation in Minority Populations

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-01-11

Completion:

2026-03-31

Conditions

• Kidney Diseases

Interventions

• OTHER

No Results Yet

NCT04536805 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

44 participants

Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-11-17

Completion:

2031-11-30

Conditions

• Prostate Cancer

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04522544 | ACTIVE_NOT_RECRUITING | PHASE2

55 participants

Durvalumab and Tremelimumab in Combination With Y-90 SIRT for Intermediate Stage HCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-12-15

Completion:

2027-07-31

Conditions

• Hepatocellular Carcinoma Non-resectable
• HCC

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04510636 | RECRUITING | PHASE2

40 participants

Study of Pembrolizumab With Bendamustine in Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-12-20

Completion:

2026-11-01

Conditions

• Classical Hodgkin Lymphoma
• Relapsed Cancer
• Refractory Cancer

Interventions

• DRUG

No Results Yet

NCT04456920 | COMPLETED | NA

193 participants

Pain Monitoring After Breast Biopsy: Benefit of E-health

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-02-09

Completion:

2023-11-20

Conditions

• Breast Cancer
• Biopsy Wound

Interventions

• OTHER

Results Available

NCT04414202 | ACTIVE_NOT_RECRUITING

519 participants

Observational Study of Intra-operative Partial Irradiation of Invasive Ductal Breast Carcinomas With a Good Prognosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2009-12-15

Completion:

2023-10-16

Conditions

• Invasive Breast Cancer
• Breast-conserving Surgery

Interventions

• PROCEDURE
• RADIATION

Results Available

NCT04353804 | ACTIVE_NOT_RECRUITING | NA

160 participants

Returning to Everyday Tasks Utilizing Rehabilitation Networks-III (RETURN-III)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-10-03

Completion:

2026-04-14

Conditions

• Cognitive Rehabilitation
• ICU Survivorship
• Intensive Care Unit
• ICU

Interventions

• OTHER

No Results Yet

NCT04346225 | SUSPENDED | PHASE2

75 participants

Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-07-16

Completion:

2026-12-31

Conditions

• Prostate Cancer
• Advanced Prostate Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04323722 | COMPLETED | NA

53 participants

Impact of Bladder Depletion on Mesorectal Movements During Radiotherapy in Rectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-09-08

Completion:

2024-09-11

Conditions

• Rectal Cancer

Interventions

• PROCEDURE

Results Available

NCT04318938 | COMPLETED | PHASE2

118 participants

Advancing Brigatinib Properties in ALK+ NSCLC Patients by Deep Phenotyping

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-03-30

Completion:

2026-05-30

Conditions

• NSCLC

Interventions

• DRUG

No Results Yet

NCT04282395 | ACTIVE_NOT_RECRUITING | NA

284 participants

Resilience-Based Diabetes Self-Management Education (RB-DSME) for African Americans

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-01-25

Completion:

2025-04-26

Conditions

• Type 2 Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT04277546 | TERMINATED | PHASE2

57 participants

Open-label Extension Study of Brazikumab in Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-03-03

Completion:

2023-10-10

Conditions

• Ulcerative Colitis

Interventions

• DRUG

Results Available

NCT04252508 | COMPLETED | NA

80 participants

Impact of a Double-reading Animated Film (Child, Parents) in Preoperative on the Anxiety of Children Upon Arrival at the Operating Room

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2019-10-09

Completion:

2022-05-02

Conditions

• Anxiety
• Surgery
• Pediatric ALL

Interventions

• OTHER

No Results Yet

NCT04225039 | ACTIVE_NOT_RECRUITING | PHASE2

39 participants

Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2020-06-23

Completion:

2022-09-08

Conditions

• Glioblastoma

Interventions

• DRUG
• PROCEDURE

Results Available