Clinical Trials

NCT04475939 | COMPLETED | PHASE3

666 participants

Placebo-controlled Study Comparing Niraparib Plus Pembrolizumab Versus Placebo Plus Pembrolizumab as Maintenance Therapy in Participants With Advanced/Metastatic Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2020-10-26

Completion:

2025-02-26

Conditions

• Lung Cancer, Non-Small Cell

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04463121 | COMPLETED | NA

22 participants

Preload and Autonomic Responses With Cardiac Neuromodulation Therapy (CNT) (CS-06)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2020-08-07

Completion:

2023-02-16

Conditions

• Bradycardia
• Hypertension, Systolic

Interventions

• DEVICE

No Results Yet

NCT04457284 | COMPLETED | PHASE2

18 participants

Temozolomide, Cisplatin, and Nivolumab in People With Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2020-11-18

Completion:

2026-06-17

Conditions

• Colorectal Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT04335682 | COMPLETED | PHASE2

111 participants

Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2021-08-17

Completion:

2025-09-01

Conditions

• Metastatic Prostate Cancer
• Prostate Cancer Metastatic
• Prostate Cancer
• Castrate Resistant Prostate Cancer
• Hormone Sensitive Prostate Cancer
• Non-metastatic Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04308720 | ACTIVE_NOT_RECRUITING

217 participants

Circulating Tumor DNA and Immunophenotyping as Potential Biomarkers With Regional Nodal Irradiation for Breast Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2019-10-01

Completion:

2028-10-20

Conditions

• Breast Cancer

No Results Yet

NCT04272307 | COMPLETED | EARLY_PHASE1

40 participants

MIcroorganisms as Triggers in Acute Severe Ulcerative Colitis and Their Influence on Medical Therapy Efficacy: a Multi-omics Pilot Approach.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2020-05-14

Completion:

2021-11-03

Conditions

• Inflammatory Bowel Diseases
• Colitis
• Ulcerative

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT04255849 | ACTIVE_NOT_RECRUITING | PHASE3

700 participants

Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2021-02-23

Completion:

2026-07-31

Conditions

• HPV Positive Oropharyngeal Squamous Cell Carcinoma
• HIV-1-infection
• HPV Infection

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04254627 | COMPLETED | PHASE1

20 participants

TNF and Glucocorticoid Antagonist for GWI Associated Multi-symptom Disease Homeostasis Reset

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2021-09-24

Completion:

2025-09-30

Conditions

• Gulf War Illness

Interventions

• DRUG

No Results Yet

NCT04245891 | COMPLETED

265 participants

Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2016-05-01

Completion:

2017-11-30

Conditions

• Caesarean Section;Stillbirth

No Results Yet

NCT04207346 | COMPLETED | NA

59 participants

Transcranial Magnetic Stimulation to Improve Functioning in Veterans With PTSD

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2020-12-01

Completion:

2025-09-30

Conditions

• PTSD

Interventions

• DEVICE

No Results Yet

NCT04206553 | COMPLETED | PHASE2/PHASE3

106 participants

A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Bullous Pemphigoid

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2020-10-28

Completion:

2024-07-12

Conditions

• Bullous Pemphigoid

Interventions

• DRUG

Results Available

NCT04132804 | COMPLETED | NA

31 participants

Effect of Tai Chi as Treatment for IBS-C

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2020-07-21

Completion:

2021-04-30

Conditions

• Irritable Bowel Syndrome With Constipation

Interventions

• BEHAVIORAL

Results Available

NCT04127032 | RECRUITING | NA

250 participants

Internet-Delivered Cognitive Behaviour Therapy for Public Safety Personnel

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-12-01

Completion:

2028-03-31

Conditions

• Depression, Anxiety
• Psychological Trauma

Interventions

• BEHAVIORAL

No Results Yet

NCT04109586 | COMPLETED | NA

62 participants

Diet and Fat Mass After Traumatic Spinal Cord Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-09-15

Completion:

2025-12-30

Conditions

• Obesity
• Metabolic Disease
• Spinal Cord Injuries

Interventions

• BEHAVIORAL

No Results Yet

NCT04102098 | COMPLETED | PHASE3

668 participants

A Study of Atezolizumab Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or Ablation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-12-31

Completion:

2022-10-21

Conditions

• Carcinoma, Hepatocellular

Interventions

• DRUG

Results Available

NCT04093986 | RECRUITING

200 participants

Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2019-12-22

Completion:

2028-12-31

Conditions

• Sickle Cell Disease
• Sickle Cell Anemia

Interventions

• OTHER

No Results Yet

NCT04092686 | COMPLETED | PHASE3

464 participants

A Clinical Trial That Will Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic People With Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-10-14

Completion:

2023-06-14

Conditions

• Schizophrenia

Interventions

• DRUG

Results Available

NCT04073888 | TERMINATED | NA

22 participants

Study of the Spermatic Characteristics of Patients With Fabry Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2009-02-20

Completion:

2013-10-18

Conditions

• Fabry Disease

Interventions

• PROCEDURE

No Results Yet

NCT04070612 | COMPLETED

122 participants

National Prospective Cohort for Monitoring Children With Severe Autoimmune Cytopenia.

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2007-04-04

Completion:

2012-06-08

Conditions

• Cytopenia
• Autoimmune Haemolytic Anaemia
• Thrombocytopenic Purpura, Immune

Interventions

• OTHER

No Results Yet

NCT04070599 | COMPLETED | PHASE3

70 participants

Initial Hemato-immunological Profile on the Evolution of Immunological Thrombopenic Purpura.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2011-04-12

Completion:

2014-03-05

Conditions

• Immune Thrombocytopenic Purpura
• Autoimmune Thrombocytopenia
• Thrombopenia

Interventions

• BIOLOGICAL

No Results Yet

NCT04068961 | COMPLETED

64 participants

New Strategies of Genetic Study of Patients With Oculocutaneous Albinism

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2010-09-15

Completion:

2010-10-31

Conditions

• Oculocutaneous Albinism
• Mutation

Interventions

• OTHER

No Results Yet

NCT04068415 | COMPLETED

516 participants

Development of a Constipation Risk Assessment Scale for Hospitalized Patients.

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2012-05-06

Completion:

2014-04-16

Conditions

• Constipation

Interventions

• OTHER

No Results Yet

NCT04068389 | COMPLETED

62 participants

Ultrafine Particles and Fetal Contamination

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2009-12-22

Completion:

2012-11-09

Conditions

• Lung; Premature
• Pollution; Exposure

Interventions

• PROCEDURE

No Results Yet

NCT04068350 | COMPLETED

582 participants

Epidemiological Study of Post-operative Chronic Pediatric Pain.

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2010-03-21

Completion:

2011-12-21

Conditions

• Chronic Pain
• Postoperative Pain

Interventions

• OTHER

No Results Yet

NCT04056559 | COMPLETED | NA

14 participants

Normative Assessment of Adaptable Mouthguards.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2011-09-09

Completion:

2012-06-29

Conditions

• Oral Manifestations

Interventions

• DEVICE

No Results Yet

NCT04045561 | COMPLETED

10 participants

Development of a Standardized Reference Guide for Tuning Adherence to Dispense During a Initial Pharmaceutical Consulting (CP ) to the Patient With Multiple Myeloma Oral Chemotherapy Primocure

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2015-06-01

Completion:

2016-12-31

Conditions

• Multiple Myeloma

No Results Yet

NCT04042584 | COMPLETED | NA

215 participants

Visio-conference for Pre-hospital Triage of Stroke Suspicions

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-11-20

Completion:

2021-12-09

Conditions

• Stroke
• Stroke, Acute
• Stroke, Ischemic
• Cerebrovascular Disorders

Interventions

• PROCEDURE

No Results Yet

NCT04018066 | COMPLETED | NA

34 participants

The Effect of Concord Grape Polyphenol-soy Protein Isolate Complex (GP-SPI) on Gut Microbiota

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-06-28

Completion:

2019-12-20

Conditions

• Mechanisms, Defense

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT04009291 | COMPLETED | PHASE2

59 participants

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-08-27

Completion:

2020-03-06

Conditions

• Hypoparathyroidism
• Endocrine System Diseases
• Parathyroid Diseases

Interventions

• COMBINATION_PRODUCT

Results Available

NCT04007042 | COMPLETED

100 participants

Validation of a Short Questionnaire (SSI) for Sleep Disorders in Patients With Alcohol

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2012-01-15

Completion:

2013-01-15

Conditions

• Alcohol Dependence
• Sleep Disorder

No Results Yet

NCT03999489 | COMPLETED

708 participants

Study of the Psychometric Properties and a Measure of Utility Determinants ( the SF- 6D) in Patients With Early Inflammatory Low Back Pain

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2015-01-31

Completion:

2015-06-30

Conditions

• Spondylarthritis

No Results Yet

NCT03983473 | RECRUITING | NA

240 participants

Identification of Fecal Microbiota Biomarkers of Spondyloarthritis in Patients Suffering From Crohn's Disease.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2021-11-16

Completion:

2027-11-04

Conditions

• Crohn Disease
• Spondyloarthritis

Interventions

• OTHER

No Results Yet

NCT03982160 | ACTIVE_NOT_RECRUITING | PHASE4

15 participants

L-arginine to Reduce Sympathetic Nerve Activity in CKD Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2018-02-01

Completion:

2026-12-31

Conditions

• Chronic Kidney Disease

Interventions

• DRUG
• OTHER

No Results Yet

NCT03976622 | ENROLLING_BY_INVITATION

450 participants

Analysis of Inflammation in the Vitiligo and Other Inflammatory Skin Diseases: Psoriasis, Atopic Dermatitis and Alopecia Areata

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2020-01-14

Completion:

2027-06-03

Conditions

• Vitiligo
• Psoriasis
• Alopecia Areata
• Atopic Dermatitis

Interventions

• BIOLOGICAL

No Results Yet

NCT03868293 | RECRUITING | NA

10 participants

Low Intensity Focused Ultrasound Epilepsy: A Pilot Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-02-07

Completion:

2027-03-09

Conditions

• Drug Resistant Epilepsy

Interventions

• DEVICE

No Results Yet

NCT03841734 | COMPLETED | PHASE3

8 participants

Study of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBO

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2020-02-04

Completion:

2023-07-26

Conditions

• Arteritis, Giant Cell
• Blindness and Low Vision

Interventions

• DRUG

No Results Yet

NCT03791073 | RECRUITING

200 participants

New Biomarkers in Pancreatic Cancer Using EXPEL Concept

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-18

Start Date:

2018-01-01

Completion:

2019-01-01

Conditions

• Oncology

No Results Yet

NCT03768570 | ACTIVE_NOT_RECRUITING | PHASE2

82 participants

Trimodality Therapy With/Out Durvalumab to Treat Patients With Muscle-Invasive Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-10-25

Completion:

2026-10-31

Conditions

• Bladder Cancer

Interventions

• DRUG

No Results Yet

NCT03762109 | COMPLETED | PHASE2

116 participants

The Use of Dantrolene to Improve Analgesia in Posterior Lumbar Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2019-07-29

Completion:

2024-06-01

Conditions

• Lumbar Spine Injury

Interventions

• DRUG

Results Available

NCT03757377 | TERMINATED | NA

203 participants

Moderato System in Patients With Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-18

Start Date:

2017-08-30

Completion:

2021-05-13

Conditions

• Hypertension, Resistant to Conventional Therapy
• Atrioventricular Block

Interventions

• DEVICE

No Results Yet