Clinical Trials

NCT04125095 | ACTIVE_NOT_RECRUITING

367 participants

Estimating Setup Uncertainty in Pediatric Proton Therapy Using Volumetric Images

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-17

Start Date:

2020-01-28

Completion:

2027-10-31

Conditions

• Pediatric Cancer

No Results Yet

NCT04083183 | RECRUITING | PHASE1/PHASE2

40 participants

Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2020-06-16

Completion:

2028-01-09

Conditions

• Non-Malignant Neoplasm

Interventions

• BIOLOGICAL
• DRUG
• RADIATION
• PROCEDURE

No Results Yet

NCT04077099 | RECRUITING | PHASE1/PHASE2

231 participants

A Study of REGN5093 in Adult Patients With Mesenchymal Epithelial Transition Factor (MET)-Altered Advanced Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2020-01-07

Completion:

2032-04-22

Conditions

• NSCLC

Interventions

• DRUG

No Results Yet

NCT04065776 | RECRUITING | NA

74 participants

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2019-08-28

Completion:

2027-07-31

Conditions

• Glioma
• Pilocytic Astrocytoma
• Pilomyxoid Astrocytoma
• Pleomorphic Xanthoastrocytoma
• Ganglioglioma
• Optic Pathway Glioma
• Diffuse Astrocytoma

Interventions

• RADIATION

No Results Yet

NCT04055649 | RECRUITING | PHASE2

62 participants

ONC201 Plus Weekly Paclitaxel in Patients With Platinum Refractory or Resistant Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2020-01-21

Completion:

2027-05-28

Conditions

• Malignant Ovarian Epithelial Tumor
• Platinum-Resistant Fallopian Tube Carcinoma
• Platinum-Resistant Ovarian Carcinoma
• Platinum-Resistant Primary Peritoneal Carcinoma
• Recurrent Fallopian Tube Carcinoma
• Recurrent Ovarian Carcinoma
• Recurrent Primary Peritoneal Carcinoma
• Refractory Fallopian Tube Carcinoma
• Refractory Ovarian Carcinoma
• Refractory Primary Peritoneal Carcinoma

Interventions

• DRUG
• OTHER

No Results Yet

NCT04045600 | RECRUITING | NA

24 participants

Refinements of Functional Communication Training

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2021-05-03

Completion:

2026-12-31

Conditions

• Aggression
• Self-injurious Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT04036682 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

284 participants

A Phase 1/2 Trial of CLN-081 in Patients With Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2019-10-31

Completion:

2025-10-13

Conditions

• Non Small Cell Lung Cancer
• EGFR Exon 20 Mutation

Interventions

• DRUG

No Results Yet

NCT04024761 | RECRUITING | PHASE1

50 participants

A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2019-08-31

Completion:

2026-12-01

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndromes
• Myeloproliferative Neoplasm
• Juvenile Myelomonocytic Leukemia

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04023591 | ACTIVE_NOT_RECRUITING

70 participants

Nerve Transfer After Spinal Cord Injury- Multi-center

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-17

Start Date:

2020-04-13

Completion:

2030-03-31

Conditions

• Tetraplegia
• Spinal Cord Injuries
• Quadriplegia Flaccid

Interventions

• PROCEDURE

No Results Yet

NCT04004416 | COMPLETED | PHASE4

143 participants

Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2020-01-16

Completion:

2025-02-28

Conditions

• Schizophrenia
• Bipolar Disorder
• Healthy
• Psychosis
• Schizophreniform Disorders
• Schizo Affective Disorder
• Major Depression With Psychotic Features

Interventions

• OTHER
• DRUG

Results Available

NCT03945721 | ACTIVE_NOT_RECRUITING | PHASE1

21 participants

A Phase I Study of Niraparib Administered Concurrently With Postoperative RT in Triple Negative Breast Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2019-07-11

Completion:

2026-12-31

Conditions

• Triple Negative Breast Cancer
• Residual Disease

Interventions

• DRUG
• RADIATION

No Results Yet

NCT03935750 | ACTIVE_NOT_RECRUITING | NA

1272 participants

STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2020-07-28

Completion:

2028-05-31

Conditions

• Anterior Cruciate Ligament Injury
• Anterior Cruciate Ligament Reconstruction
• Joint Instability

Interventions

• PROCEDURE

No Results Yet

NCT03927833 | ACTIVE_NOT_RECRUITING | NA

1700 participants

Cycled Phototherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2020-07-16

Completion:

2025-11-04

Conditions

• Hyper Bilirubinemia
• Premature Infant

Interventions

• DEVICE

No Results Yet

NCT03886558 | COMPLETED | NA

30 participants

Multicomponent Program on a Group of Nonagenarians

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-04-01

Completion:

2019-05-01

Conditions

• Quality of Life
• Healthy
• Aging
• Physical Activity

Interventions

• OTHER

No Results Yet

NCT03837405 | COMPLETED | NA

125 participants

(R33 Phase) DELISH Study: Diabetes Education to Lower Insulin, Sugars, and Hunger

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-12-12

Completion:

2021-06-17

Conditions

• Type 2 Diabetes Mellitus

Interventions

• BEHAVIORAL

Results Available

NCT03833479 | ACTIVE_NOT_RECRUITING | PHASE2

134 participants

TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer After Chemo-radiation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2019-06-28

Completion:

2028-07-31

Conditions

• Cervical Cancer
• Advanced Cancer

Interventions

• OTHER
• DRUG

No Results Yet

NCT03755804 | ACTIVE_NOT_RECRUITING | PHASE2

232 participants

Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-12-12

Completion:

2027-01-01

Conditions

• Hodgkin Lymphoma

Interventions

• DRUG
• OTHER
• RADIATION

No Results Yet

NCT03747367 | COMPLETED | NA

55 participants

The Microbiome and Resilience to Sleep and Circadian Disruption

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2015-10-21

Completion:

2020-03-12

Conditions

• Sleep Deprivation
• Circadian Dysregulation
• Stress

Interventions

• BEHAVIORAL
• DIETARY_SUPPLEMENT

No Results Yet

NCT03708731 | ACTIVE_NOT_RECRUITING

36 participants

Exploring Adherence Monitoring in Sickle Cell Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-17

Start Date:

2019-03-12

Completion:

2022-08-10

Conditions

• Sickle Cell Disease

No Results Yet

NCT03698994 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-11-14

Completion:

2022-03-31

Conditions

• Advanced Malignant Solid Neoplasm
• Recurrent Ependymal Tumor
• Recurrent Ewing Sarcoma
• Recurrent Glioma
• Recurrent Hepatoblastoma
• Recurrent Histiocytic and Dendritic Cell Neoplasm
• Recurrent Langerhans Cell Histiocytosis
• Recurrent Malignant Germ Cell Tumor
• Recurrent Malignant Solid Neoplasm
• Recurrent Medulloblastoma
• Recurrent Neuroblastoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Osteosarcoma
• Recurrent Peripheral Primitive Neuroectodermal Tumor
• Recurrent Primary Malignant Central Nervous System Neoplasm
• Recurrent Rhabdoid Tumor
• Recurrent Rhabdomyosarcoma
• Recurrent Soft Tissue Sarcoma
• Refractory Ependymoma
• Refractory Ewing Sarcoma
• Refractory Glioma
• Refractory Hepatoblastoma
• Refractory Histiocytic and Dendritic Cell Neoplasm
• Refractory Langerhans Cell Histiocytosis
• Refractory Malignant Germ Cell Tumor
• Refractory Malignant Solid Neoplasm
• Refractory Medulloblastoma
• Refractory Neuroblastoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Osteosarcoma
• Refractory Peripheral Primitive Neuroectodermal Tumor
• Refractory Primary Malignant Central Nervous System Neoplasm
• Refractory Rhabdoid Tumor
• Refractory Rhabdomyosarcoma
• Refractory Soft Tissue Sarcoma
• Wilms Tumor

Interventions

• OTHER
• DRUG

Results Available

NCT03645915 | COMPLETED

36 participants

GLUT1: A Novel Tool re fl Ecting Proliferative Activity of Lung Neuroendocrine Tumors

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-17

Start Date:

2014-01-01

Completion:

2016-11-13

Conditions

• Lung Tumor

Interventions

• OTHER

No Results Yet

NCT03631199 | TERMINATED | PHASE3

673 participants

Study of Efficacy and Safety of Pembrolizumab Plus Platinum-based Doublet Chemotherapy With or Without Canakinumab in Previously Untreated Locally Advanced or Metastatic Non-squamous and Squamous NSCLC Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-12-21

Completion:

2021-08-09

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT03615547 | WITHDRAWN | PHASE3

0 participants

Interest of Clomiphene Citrate in Patients With Non-obstructive Azoospermia on the Quantity of Sperm Cells

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2026-01-31

Completion:

2029-01-31

Conditions

• Azoospermia, Nonobstructive

Interventions

• DRUG
• OTHER

No Results Yet

NCT03601546 | COMPLETED

300 participants

Feasibility of Implementing a Cohort of People Living With Hepatitis C in Vietnam

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-17

Start Date:

2018-09-13

Completion:

2021-11-03

Conditions

• Hepatitis C Infection

Interventions

• OTHER

No Results Yet

NCT03596411 | COMPLETED

100 participants

The Detection of Barrett's Esophagus by Gastrointestinal Endoscopy Prevents Esophageal Carcinoma in Morbid Obese After Sleeve Gastrectomy

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-17

Start Date:

2018-05-17

Completion:

2024-05-17

Conditions

• Gastroesophageal Reflux

No Results Yet

NCT03576989 | COMPLETED | NA

96 participants

Impact of Omega-3 Fatty Acid Oral Therapy on Healing of Chronic Venous Leg Ulcers in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2019-04-15

Completion:

2024-12-18

Conditions

• Chronic Venous Leg Ulcers

Interventions

• DIETARY_SUPPLEMENT
• OTHER

Results Available

NCT03569293 | COMPLETED | PHASE3

912 participants

Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-08-13

Completion:

2021-01-06

Conditions

• Atopic Dermatitis

Interventions

• DRUG

Results Available

NCT03556332 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

A Study of Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab for Patients With Relapsed/Refractory Myeloma With Salvage Autologous Hematopoietic Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-07-02

Completion:

2027-07-31

Conditions

• Multiple Myeloma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03541720 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

13 participants

18F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2019-04-30

Completion:

2027-01-01

Conditions

• Neuroblastoma
• Pheochromocytoma

Interventions

• DRUG

No Results Yet

NCT03456089 | ENROLLING_BY_INVITATION | NA

100 participants

Measurement of Bladder Pressure With a Novel External Device, Comparison to Urodynamics Testing

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-04-15

Completion:

2026-12-30

Conditions

• Urinary Bladder, Neurogenic
• Urodynamics

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03414502 | RECRUITING | PHASE3

400 participants

Treatment of Rheumatoid Arthritis With DMARDs: Predictors of Response

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2007-12-10

Completion:

2028-03-31

Conditions

• Rheumatoid Arthritis

Interventions

• DRUG

No Results Yet

NCT03362060 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

PVX-410 Vaccine Plus Pembrolizumab in HLA-A2+ Metastatic Triple Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2017-12-12

Completion:

2026-12-30

Conditions

• Triple Negative Breast Cancer
• Metastatic Breast Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03361020 | ACTIVE_NOT_RECRUITING

434 participants

Obstructive Sleep Apnea in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-17

Start Date:

2018-01-23

Completion:

2023-07-31

Conditions

• Obstructive Sleep Apnea
• Hodgkin Lymphoma

No Results Yet

NCT03314805 | COMPLETED | PHASE2

67 participants

PG2 Breast Cancer Evaluation in Adjuvant Medicine Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-03-01

Completion:

2021-05-26

Conditions

• Cancer-related Fatigue
• Neutropenia, Malignant

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03263650 | COMPLETED | PHASE2

96 participants

Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2017-10-03

Completion:

2026-06-10

Conditions

• Prostate Cancer Aggressiveness
• Prostate Carcinoma

Interventions

• DRUG

No Results Yet

NCT03241784 | COMPLETED | PHASE1

3 participants

Ph1 T-Regulatory Cells in Amyotrophic Lateral Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2016-05-16

Completion:

2018-01-05

Conditions

• ALS (Amyotrophic Lateral Sclerosis)

Interventions

• BIOLOGICAL

Results Available

NCT03223766 | ACTIVE_NOT_RECRUITING

1000 participants

Evaluation of Proton Therapy in Pediatric Cancer Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-17

Start Date:

2017-08-01

Completion:

2037-07-31

Conditions

• Tumor

No Results Yet

NCT03216187 | TERMINATED | PHASE3

126 participants

Swiss Multi-centre, Randomized, Placebo Controlled Trial of Pregabalin for Prevention of Persistent Pain in High Risk Patients Undergoing Breast Cancer Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2018-01-09

Completion:

2024-06-11

Conditions

• Persistent Postoperative Pain

Interventions

• DRUG

No Results Yet

NCT03213704 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2017-08-23

Completion:

2024-09-30

Conditions

• Advanced Malignant Solid Neoplasm
• Recurrent Ependymoma
• Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
• Recurrent Glioma
• Recurrent Hepatoblastoma
• Recurrent Kidney Wilms Tumor
• Recurrent Langerhans Cell Histiocytosis
• Recurrent Malignant Germ Cell Tumor
• Recurrent Malignant Glioma
• Recurrent Malignant Solid Neoplasm
• Recurrent Medulloblastoma
• Recurrent Neuroblastoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Osteosarcoma
• Recurrent Rhabdoid Tumor
• Recurrent Rhabdomyosarcoma
• Recurrent Soft Tissue Sarcoma
• Refractory Ependymoma
• Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
• Refractory Glioma
• Refractory Hepatoblastoma
• Refractory Langerhans Cell Histiocytosis
• Refractory Malignant Germ Cell Tumor
• Refractory Malignant Glioma
• Refractory Malignant Solid Neoplasm
• Refractory Medulloblastoma
• Refractory Neuroblastoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Osteosarcoma
• Refractory Primary Central Nervous System Neoplasm
• Refractory Rhabdoid Tumor
• Refractory Rhabdomyosarcoma
• Refractory Soft Tissue Sarcoma

Interventions

• PROCEDURE
• DRUG

Results Available

NCT03213041 | COMPLETED | PHASE2

12 participants

Pembrolizumab and Carboplatin in Treating Patients With Circulating Tumor Cells Positive Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-17

Start Date:

2017-09-14

Completion:

2021-06-01

Conditions

• Estrogen Receptor Negative
• Estrogen Receptor Positive
• HER2/Neu Negative
• Progesterone Receptor Negative
• Recurrent Breast Carcinoma
• Stage IV Breast Cancer
• Triple-Negative Breast Carcinoma

Interventions

• DRUG
• OTHER
• BIOLOGICAL

Results Available