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Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)

NCT03569293 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 912

Last updated 2025-10-24

Study results available
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Summary

The objective of this study is to assess the efficacy and safety of upadacitinib for the treatment of adolescent and adult participants with moderate to severe atopic dermatitis (AD) who are candidates for systemic therapy.

Conditions

Interventions

DRUG

Placebo for Upadacitinib

Tablets taken orally once a day

DRUG

Upadacitinib

Tablets taken orally once a day

Sponsors & Collaborators

Principal Investigators

  • ABBVIE INC. · AbbVie

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
12 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-08-13
Primary Completion
2021-01-06
Completion
2025-10-10
FDA Drug
Yes

Countries

  • United States
  • Argentina
  • Australia
  • Bosnia and Herzegovina
  • Bulgaria
  • Canada
  • China
  • Colombia
  • Croatia
  • Denmark
  • Estonia
  • Finland
  • France
  • Germany
  • Italy
  • Japan
  • Malaysia
  • New Zealand
  • Puerto Rico
  • Romania
  • Russia
  • Switzerland
  • Turkey (Türkiye)
  • Ukraine
  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03569293 on ClinicalTrials.gov