Clinical Trials

NCT04125095 | ACTIVE_NOT_RECRUITING

367 participants

Estimating Setup Uncertainty in Pediatric Proton Therapy Using Volumetric Images

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-17
Start Date:: 2020-01-28
Completion:: 2027-10-31

Conditions

Pediatric Cancer

No Results Yet

NCT04083183 | RECRUITING | PHASE1/PHASE2

40 participants

Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2020-06-16
Completion:: 2028-01-09

Conditions

Non-Malignant Neoplasm

Interventions

BIOLOGICAL
DRUG
RADIATION
PROCEDURE

No Results Yet

NCT04077099 | RECRUITING | PHASE1/PHASE2

231 participants

A Study of REGN5093 in Adult Patients With Mesenchymal Epithelial Transition Factor (MET)-Altered Advanced Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2020-01-07
Completion:: 2032-04-22

Conditions

NSCLC

Interventions

DRUG

No Results Yet

NCT04065776 | RECRUITING | NA

74 participants

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2019-08-28
Completion:: 2027-07-31

Conditions

Glioma
Pilocytic Astrocytoma
Pilomyxoid Astrocytoma
Pleomorphic Xanthoastrocytoma
Ganglioglioma
Optic Pathway Glioma
Diffuse Astrocytoma

Interventions

RADIATION

No Results Yet

NCT04055649 | RECRUITING | PHASE2

62 participants

ONC201 Plus Weekly Paclitaxel in Patients With Platinum Refractory or Resistant Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2020-01-21
Completion:: 2027-05-28

Conditions

Malignant Ovarian Epithelial Tumor
Platinum-Resistant Fallopian Tube Carcinoma
Platinum-Resistant Ovarian Carcinoma
Platinum-Resistant Primary Peritoneal Carcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Ovarian Carcinoma
Recurrent Primary Peritoneal Carcinoma
Refractory Fallopian Tube Carcinoma
Refractory Ovarian Carcinoma
Refractory Primary Peritoneal Carcinoma

Interventions

DRUG
OTHER

No Results Yet

NCT04045600 | RECRUITING | NA

24 participants

Refinements of Functional Communication Training

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2021-05-03
Completion:: 2026-12-31

Conditions

Aggression
Self-injurious Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT04036682 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

284 participants

A Phase 1/2 Trial of CLN-081 in Patients With Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2019-10-31
Completion:: 2025-10-13

Conditions

Non Small Cell Lung Cancer
EGFR Exon 20 Mutation

Interventions

DRUG

No Results Yet

NCT04024761 | RECRUITING | PHASE1

50 participants

A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2019-08-31
Completion:: 2026-12-01

Conditions

Acute Myeloid Leukemia
Myelodysplastic Syndromes
Myeloproliferative Neoplasm
Juvenile Myelomonocytic Leukemia

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04023591 | ACTIVE_NOT_RECRUITING

70 participants

Nerve Transfer After Spinal Cord Injury- Multi-center

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-17
Start Date:: 2020-04-13
Completion:: 2030-03-31

Conditions

Tetraplegia
Spinal Cord Injuries
Quadriplegia Flaccid

Interventions

PROCEDURE

No Results Yet

NCT04004416 | COMPLETED | PHASE4

143 participants

Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2020-01-16
Completion:: 2025-02-28

Conditions

Schizophrenia
Bipolar Disorder
Healthy
Psychosis
Schizophreniform Disorders
Schizo Affective Disorder
Major Depression With Psychotic Features

Interventions

OTHER
DRUG

Results Available

NCT03945721 | ACTIVE_NOT_RECRUITING | PHASE1

21 participants

A Phase I Study of Niraparib Administered Concurrently With Postoperative RT in Triple Negative Breast Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2019-07-11
Completion:: 2026-12-31

Conditions

Triple Negative Breast Cancer
Residual Disease

Interventions

DRUG
RADIATION

No Results Yet

NCT03935750 | ACTIVE_NOT_RECRUITING | NA

1272 participants

STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2020-07-28
Completion:: 2028-05-31

Conditions

Anterior Cruciate Ligament Injury
Anterior Cruciate Ligament Reconstruction
Joint Instability

Interventions

PROCEDURE

No Results Yet

NCT03927833 | ACTIVE_NOT_RECRUITING | NA

1700 participants

Cycled Phototherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2020-07-16
Completion:: 2025-11-04

Conditions

Hyper Bilirubinemia
Premature Infant

Interventions

DEVICE

No Results Yet

NCT03886558 | COMPLETED | NA

30 participants

Multicomponent Program on a Group of Nonagenarians

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-04-01
Completion:: 2019-05-01

Conditions

Quality of Life
Healthy
Aging
Physical Activity

Interventions

OTHER

No Results Yet

NCT03837405 | COMPLETED | NA

125 participants

(R33 Phase) DELISH Study: Diabetes Education to Lower Insulin, Sugars, and Hunger

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-12-12
Completion:: 2021-06-17

Conditions

Type 2 Diabetes Mellitus

Interventions

BEHAVIORAL

Results Available

NCT03833479 | ACTIVE_NOT_RECRUITING | PHASE2

134 participants

TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer After Chemo-radiation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2019-06-28
Completion:: 2028-07-31

Conditions

Cervical Cancer
Advanced Cancer

Interventions

OTHER
DRUG

No Results Yet

NCT03755804 | ACTIVE_NOT_RECRUITING | PHASE2

232 participants

Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-12-12
Completion:: 2027-01-01

Conditions

Hodgkin Lymphoma

Interventions

DRUG
OTHER
RADIATION

No Results Yet

NCT03747367 | COMPLETED | NA

55 participants

The Microbiome and Resilience to Sleep and Circadian Disruption

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2015-10-21
Completion:: 2020-03-12

Conditions

Sleep Deprivation
Circadian Dysregulation
Stress

Interventions

BEHAVIORAL
DIETARY_SUPPLEMENT

No Results Yet

NCT03708731 | ACTIVE_NOT_RECRUITING

36 participants

Exploring Adherence Monitoring in Sickle Cell Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-17
Start Date:: 2019-03-12
Completion:: 2022-08-10

Conditions

Sickle Cell Disease

No Results Yet

NCT03698994 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-11-14
Completion:: 2022-03-31

Conditions

Advanced Malignant Solid Neoplasm
Recurrent Ependymal Tumor
Recurrent Ewing Sarcoma
Recurrent Glioma
Recurrent Hepatoblastoma
Recurrent Histiocytic and Dendritic Cell Neoplasm
Recurrent Langerhans Cell Histiocytosis
Recurrent Malignant Germ Cell Tumor
Recurrent Malignant Solid Neoplasm
Recurrent Medulloblastoma
Recurrent Neuroblastoma
Recurrent Non-Hodgkin Lymphoma
Recurrent Osteosarcoma
Recurrent Peripheral Primitive Neuroectodermal Tumor
Recurrent Primary Malignant Central Nervous System Neoplasm
Recurrent Rhabdoid Tumor
Recurrent Rhabdomyosarcoma
Recurrent Soft Tissue Sarcoma
Refractory Ependymoma
Refractory Ewing Sarcoma
Refractory Glioma
Refractory Hepatoblastoma
Refractory Histiocytic and Dendritic Cell Neoplasm
Refractory Langerhans Cell Histiocytosis
Refractory Malignant Germ Cell Tumor
Refractory Malignant Solid Neoplasm
Refractory Medulloblastoma
Refractory Neuroblastoma
Refractory Non-Hodgkin Lymphoma
Refractory Osteosarcoma
Refractory Peripheral Primitive Neuroectodermal Tumor
Refractory Primary Malignant Central Nervous System Neoplasm
Refractory Rhabdoid Tumor
Refractory Rhabdomyosarcoma
Refractory Soft Tissue Sarcoma
Wilms Tumor

Interventions

OTHER
DRUG

Results Available

NCT03645915 | COMPLETED

36 participants

GLUT1: A Novel Tool re fl Ecting Proliferative Activity of Lung Neuroendocrine Tumors

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-17
Start Date:: 2014-01-01
Completion:: 2016-11-13

Conditions

Lung Tumor

Interventions

OTHER

No Results Yet

NCT03631199 | TERMINATED | PHASE3

673 participants

Study of Efficacy and Safety of Pembrolizumab Plus Platinum-based Doublet Chemotherapy With or Without Canakinumab in Previously Untreated Locally Advanced or Metastatic Non-squamous and Squamous NSCLC Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-12-21
Completion:: 2021-08-09

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

Results Available

NCT03615547 | WITHDRAWN | PHASE3

0 participants

Interest of Clomiphene Citrate in Patients With Non-obstructive Azoospermia on the Quantity of Sperm Cells

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2026-01-31
Completion:: 2029-01-31

Conditions

Azoospermia, Nonobstructive

Interventions

DRUG
OTHER

No Results Yet

NCT03601546 | COMPLETED

300 participants

Feasibility of Implementing a Cohort of People Living With Hepatitis C in Vietnam

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-09-13
Completion:: 2021-11-03

Conditions

Hepatitis C Infection

Interventions

OTHER

No Results Yet

NCT03596411 | COMPLETED

100 participants

The Detection of Barrett's Esophagus by Gastrointestinal Endoscopy Prevents Esophageal Carcinoma in Morbid Obese After Sleeve Gastrectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-05-17
Completion:: 2024-05-17

Conditions

Gastroesophageal Reflux

No Results Yet

NCT03576989 | COMPLETED | NA

96 participants

Impact of Omega-3 Fatty Acid Oral Therapy on Healing of Chronic Venous Leg Ulcers in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2019-04-15
Completion:: 2024-12-18

Conditions

Chronic Venous Leg Ulcers

Interventions

DIETARY_SUPPLEMENT
OTHER

Results Available

NCT03569293 | COMPLETED | PHASE3

912 participants

Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-08-13
Completion:: 2021-01-06

Conditions

Atopic Dermatitis

Interventions

DRUG

Results Available

NCT03556332 | ACTIVE_NOT_RECRUITING | PHASE2

41 participants

A Study of Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab for Patients With Relapsed/Refractory Myeloma With Salvage Autologous Hematopoietic Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-07-02
Completion:: 2027-07-31

Conditions

Multiple Myeloma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03541720 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

13 participants

18F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2019-04-30
Completion:: 2027-01-01

Conditions

Neuroblastoma
Pheochromocytoma

Interventions

DRUG

No Results Yet

NCT03456089 | ENROLLING_BY_INVITATION | NA

100 participants

Measurement of Bladder Pressure With a Novel External Device, Comparison to Urodynamics Testing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-04-15
Completion:: 2026-12-30

Conditions

Urinary Bladder, Neurogenic
Urodynamics

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03414502 | RECRUITING | PHASE3

400 participants

Treatment of Rheumatoid Arthritis With DMARDs: Predictors of Response

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2007-12-10
Completion:: 2028-03-31

Conditions

Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT03362060 | ACTIVE_NOT_RECRUITING | PHASE1

20 participants

PVX-410 Vaccine Plus Pembrolizumab in HLA-A2+ Metastatic Triple Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2017-12-12
Completion:: 2026-12-30

Conditions

Triple Negative Breast Cancer
Metastatic Breast Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT03361020 | ACTIVE_NOT_RECRUITING

434 participants

Obstructive Sleep Apnea in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-01-23
Completion:: 2023-07-31

Conditions

Obstructive Sleep Apnea
Hodgkin Lymphoma

No Results Yet

NCT03314805 | COMPLETED | PHASE2

67 participants

PG2 Breast Cancer Evaluation in Adjuvant Medicine Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-03-01
Completion:: 2021-05-26

Conditions

Cancer-related Fatigue
Neutropenia, Malignant

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03263650 | COMPLETED | PHASE2

96 participants

Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2017-10-03
Completion:: 2026-06-10

Conditions

Prostate Cancer Aggressiveness
Prostate Carcinoma

Interventions

DRUG

No Results Yet

NCT03241784 | COMPLETED | PHASE1

3 participants

Ph1 T-Regulatory Cells in Amyotrophic Lateral Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2016-05-16
Completion:: 2018-01-05

Conditions

ALS (Amyotrophic Lateral Sclerosis)

Interventions

BIOLOGICAL

Results Available

NCT03223766 | ACTIVE_NOT_RECRUITING

1000 participants

Evaluation of Proton Therapy in Pediatric Cancer Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-17
Start Date:: 2017-08-01
Completion:: 2037-07-31

Conditions

Tumor

No Results Yet

NCT03216187 | TERMINATED | PHASE3

126 participants

Swiss Multi-centre, Randomized, Placebo Controlled Trial of Pregabalin for Prevention of Persistent Pain in High Risk Patients Undergoing Breast Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2018-01-09
Completion:: 2024-06-11

Conditions

Persistent Postoperative Pain

Interventions

DRUG

No Results Yet

NCT03213704 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2017-08-23
Completion:: 2024-09-30

Conditions

Advanced Malignant Solid Neoplasm
Recurrent Ependymoma
Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Recurrent Glioma
Recurrent Hepatoblastoma
Recurrent Kidney Wilms Tumor
Recurrent Langerhans Cell Histiocytosis
Recurrent Malignant Germ Cell Tumor
Recurrent Malignant Glioma
Recurrent Malignant Solid Neoplasm
Recurrent Medulloblastoma
Recurrent Neuroblastoma
Recurrent Non-Hodgkin Lymphoma
Recurrent Osteosarcoma
Recurrent Rhabdoid Tumor
Recurrent Rhabdomyosarcoma
Recurrent Soft Tissue Sarcoma
Refractory Ependymoma
Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Refractory Glioma
Refractory Hepatoblastoma
Refractory Langerhans Cell Histiocytosis
Refractory Malignant Germ Cell Tumor
Refractory Malignant Glioma
Refractory Malignant Solid Neoplasm
Refractory Medulloblastoma
Refractory Neuroblastoma
Refractory Non-Hodgkin Lymphoma
Refractory Osteosarcoma
Refractory Primary Central Nervous System Neoplasm
Refractory Rhabdoid Tumor
Refractory Rhabdomyosarcoma
Refractory Soft Tissue Sarcoma

Interventions

PROCEDURE
DRUG

Results Available

NCT03213041 | COMPLETED | PHASE2

12 participants

Pembrolizumab and Carboplatin in Treating Patients With Circulating Tumor Cells Positive Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-17
Start Date:: 2017-09-14
Completion:: 2021-06-01

Conditions

Estrogen Receptor Negative
Estrogen Receptor Positive
HER2/Neu Negative
Progesterone Receptor Negative
Recurrent Breast Carcinoma
Stage IV Breast Cancer
Triple-Negative Breast Carcinoma

Interventions

DRUG
OTHER
BIOLOGICAL

Results Available