Clinical Trials

NCT05089747 | RECRUITING

6000 participants

CIRculating CANcer MAster-Protocol

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2022-12-05

Completion:

2047-12-01

Conditions

• Adult With Solid Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT05083403 | TERMINATED | NA

170 participants

HPI (Hypotension Prediction Index) Care Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2022-03-28

Completion:

2024-05-14

Conditions

• Cardiopulmonary Bypass Surgery

Interventions

• DEVICE
• OTHER

Results Available

NCT05053880 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

48 participants

A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-09-22

Completion:

2024-10-25

Conditions

• Recurrent Glioblastoma Multiforme(GBM)

Interventions

• DRUG

No Results Yet

NCT05025423 | TERMINATED | PHASE2

7 participants

Phase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2022-06-21

Completion:

2025-05-14

Conditions

• Mantle Cell Lymphoma

Interventions

• DRUG

Results Available

NCT05022589 | COMPLETED | NA

32 participants

Remote Digital Health Intervention to Improve Balance and Reduce Fall Risk

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2022-08-09

Completion:

2024-04-19

Conditions

• Fall

Interventions

• OTHER

Results Available

NCT05000216 | TERMINATED | PHASE2

258 participants

COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-08-13

Completion:

2023-06-22

Conditions

• Rheumatoid Arthritis (RA)
• Systemic Lupus Erythematosus (SLE)
• Pemphigus Vulgaris
• Multiple Sclerosis (MS)
• Systemic Sclerosis (SSc)
• Pediatric SLE
• Juvenile Idiopathic Arthritis (JIA)
• Juvenile Dermatomyositis (JDM)
• Pediatric-Onset Multiple Sclerosis (POMS)

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04995081 | COMPLETED | PHASE2

60 participants

Clinical Trial for Parkinson's Disease Using Allogeneic HB-adMSCs (Early and Moderate PD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-07-16

Completion:

2025-10-03

Conditions

• Parkinson Disease

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04937660 | COMPLETED

185 participants

Treatment Patterns & Clinical Outcomes of Palbociclib Combinations in HR+HER2-MBC

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2021-07-15

Completion:

2025-04-29

Conditions

• Metastatic Breast Cancer

Results Available

NCT04925531 | COMPLETED

143 participants

Antibiotic Use in Facial Fracture Post Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2016-07-29

Completion:

2025-06-12

Conditions

• Trauma Injury

Interventions

• DRUG

No Results Yet

NCT04880109 | TERMINATED | PHASE2

16 participants

A Phase 2 Study of APX-115 in Hospitalized Patients With Confirmed Mild to Moderate COVID-19.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-10-20

Completion:

2022-04-28

Conditions

• COVID-19

Interventions

• DRUG

Results Available

NCT04879368 | COMPLETED | PHASE3

462 participants

RegoNivo vs Standard of Care Chemotherapy in AGOC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-05-05

Completion:

2025-01-14

Conditions

• Gastro-Oesophageal Cancer

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04864847 | COMPLETED

382 participants

Clinical Validation of the RENISCHEM L-FABP POC Assay

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2021-10-01

Completion:

2026-02-05

Conditions

• Acute Kidney Injury
• Contrast-induced Nephropathy

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04844866 | RECRUITING | PHASE2

213 participants

Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-08-18

Completion:

2025-01-15

Conditions

• Diffuse Large B-cell Lymphoma

Interventions

• GENETIC
• DRUG

No Results Yet

NCT04833114 | COMPLETED | PHASE3

306 participants

Polatuzumab Vedotin Plus Rituximab, Ifosfamide, Carboplatin and Etoposide (Pola-R-ICE) Versus R-ICE Alone in Second Line Treatment of Diffuse Large B-cell Lymphoma (DLBCL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-04-30

Completion:

2025-12-19

Conditions

• Relapsed Diffuse Large B-cell Lymphoma
• Refractory Diffuse Large B-Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT04811209 | RECRUITING

300 participants

MCID and PASS for Acute Pain and Quality of Recovery After Orthopedic Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2021-06-21

Completion:

2026-08-31

Conditions

• Pain Management

Interventions

• OTHER

No Results Yet

NCT04804956 | RECRUITING

100 participants

Mesorectal Microbiome and Metabolome as a Prognostic Factor in Patients With Rectal Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2021-04-01

Completion:

2027-04-01

Conditions

• Rectal Cancer

Interventions

• PROCEDURE
• BEHAVIORAL

No Results Yet

NCT04804072 | COMPLETED | NA

447 participants

INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-06-02

Completion:

2024-12-17

Conditions

• HIV Infections
• Drug Use
• Opioid Use
• Opioid-use Disorder

Interventions

• DRUG
• DIAGNOSTIC_TEST
• OTHER
• BEHAVIORAL

Results Available

NCT04802720 | ACTIVE_NOT_RECRUITING | NA

348 participants

A Study Comparing Two Types of Supportive Interventions for Caregivers of Patients With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-02-26

Completion:

2025-02-24

Conditions

• Cancer Patients
• Family Caregivers

Interventions

• OTHER

Results Available

NCT04800250 | TERMINATED | NA

8 participants

Treatment of Multiple Gingival Recession Defects Using a New Xenogenic Collagen Membrane Compared to Connective Tissue Graft: a Randomized Controlled Split-mouth Clinical Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2023-07-24

Completion:

2026-05-26

Conditions

• Gingival Recession

Interventions

• PROCEDURE

No Results Yet

NCT04796714 | RECRUITING | PHASE4

60 participants

AntiPlatelet theraPy stratEgy followiNg Left Atrial appenDAGe closurE

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2022-10-03

Completion:

2027-05-03

Conditions

• Atrial Fibrillation
• Atrial Appendage
• Anticoagulants
• Stroke
• Platelet Aggregation Inhibitors

Interventions

• DRUG
• DEVICE
• OTHER

No Results Yet

NCT04768335 | COMPLETED | NA

50 participants

Auditory Processes and Emotional Perception in Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-03-31

Completion:

2022-12-22

Conditions

• Basic Auditory Processes
• Emotional Perception
• Source Monitoring Deficits

Interventions

• BEHAVIORAL

No Results Yet

NCT04759456 | COMPLETED | NA

60 participants

Obstructive Sleep Apnea and Comprehensive Remotely-supervised Rehabilitation Program

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-10-25

Completion:

2025-05-31

Conditions

• Obstructive Sleep Apnea

Interventions

• OTHER

No Results Yet

NCT04726306 | ENROLLING_BY_INVITATION

30 participants

Diagnostic Precision and Accuracy Using the Teed Scoring System Versus the O'Neill Grading System

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2023-02-01

Completion:

2026-12-31

Conditions

• Otic Barotrauma
• Pressure Injury
• Ear Injury
• Barotitis
• Barotrauma

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04640753 | RECRUITING

200 participants

Peroral Endoscopic Myotomy for the Treatment of Achalasia

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2019-02-06

Completion:

2027-02-05

Conditions

• Achalasia

Interventions

• PROCEDURE

No Results Yet

NCT04638439 | COMPLETED | PHASE1

20 participants

The Safety and Efficacy of Sequential Treatment of Ropeginterferon Alfa-2b (P1101) and Anti-PD1 in Interferon-Naive Adults With Chronic Hepatitis B or D Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2022-08-17

Completion:

2026-04-08

Conditions

• Chronic Hepatitis B Infection
• Chronic Hepatitis D Infection

Interventions

• DRUG

No Results Yet

NCT04637256 | COMPLETED

500 participants

Evaluation of Outcomes From Treatment of Benign or Malignant Gastroesophageal Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2019-03-06

Completion:

2021-02-27

Conditions

• Pancreatic Malignant Neoplasm Primary

No Results Yet

NCT04637243 | ACTIVE_NOT_RECRUITING

126 participants

Outcomes From Treatment Liver and Bile Duct Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2023-03-09

Completion:

2026-12-31

Conditions

• Benign or Malignant Liver and Bile Duct Disease

Interventions

• OTHER

No Results Yet

NCT04622046 | COMPLETED | PHASE3

25 participants

A Phase 3 Study of ALXN2060 in Japanese Participants With Symptomatic ATTR-CM

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2020-11-13

Completion:

2023-11-08

Conditions

• Symptomatic Transthyretin Amyloid Cardiomyopathy

Interventions

• DRUG

Results Available

NCT04618406 | COMPLETED | NA

158 participants

The Effect of Negative Pressure Wound Therapy on Wound Healing in Major Amputations of the Lower Limb

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-11-01

Completion:

2025-05-01

Conditions

• Negative-Pressure Wound Therapy
• Amputation
• Wound Heal

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04603248 | COMPLETED | NA

50 participants

A Study for Identification of Immune Determinants for Response to Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2020-12-03

Completion:

2026-03-18

Conditions

• Head and Neck Squamous Cell Carcinoma (HNSCC)

Interventions

• DRUG

No Results Yet

NCT04599309 | ACTIVE_NOT_RECRUITING

35 participants

Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell Carcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-10

Start Date:

2020-10-15

Completion:

2023-03-31

Conditions

• Cancer
• Head and Neck Squamous Cell Carcinoma
• Head and Neck Cancer

No Results Yet

NCT04599270 | RECRUITING | NA

700 participants

Efficiency of Prevention Program Dedicated to Addictive Behaviors (PREVENTURE) of Vulnerable Teenagers

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-10-01

Completion:

2026-10-01

Conditions

• Addiction, Alcohol
• Addiction, Substance

Interventions

• OTHER

No Results Yet

NCT04587128 | ACTIVE_NOT_RECRUITING | PHASE2

34 participants

Early-Line Anti-EGFR Therapy to Facilitate Retreatment for Select Patients With mCRC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2020-10-19

Completion:

2029-10-31

Conditions

• Metastatic Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT04572256 | RECRUITING | EARLY_PHASE1

30 participants

MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-02-01

Completion:

2027-06-30

Conditions

• ACL Injury
• Meniscus Tear
• Post-traumatic Osteoarthritis

Interventions

• DRUG

No Results Yet

NCT04571658 | RECRUITING | NA

375 participants

NEPTUNE Match Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2022-05-02

Completion:

2029-12-30

Conditions

• Nephrotic Syndrome in Children
• Focal Segmental Glomerulosclerosis
• Minimal Change Disease
• Minimal Change Nephrotic Syndrome
• Membranous Nephropathy
• FSGS
• MCD
• MCD - Minimal Change Disease
• Alport Syndrome

Interventions

• OTHER

No Results Yet

NCT04560036 | RECRUITING | NA

40 participants

FAZA PETMRI Gastro-Oesophageal Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2020-09-15

Completion:

2027-12-31

Conditions

• Metastasized Gastro-Oesophageal Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04548648 | ACTIVE_NOT_RECRUITING | PHASE2

10 participants

A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2020-10-15

Completion:

2025-05-14

Conditions

• Central Nervous System Lymphoma

Interventions

• DRUG

Results Available

NCT04540302 | COMPLETED | NA

357 participants

The Merit WRAPSODY AV Access Efficacy Study (WAVE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-03-09

Completion:

2024-02-22

Conditions

• Venous Stenosis
• Venous Occlusion

Interventions

• DEVICE

Results Available

NCT04526353 | RECRUITING | PHASE2

50 participants

Early Oxybutinin Treatment for Boys With Posterior Urethral Valves

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2020-09-10

Completion:

2028-02-29

Conditions

• Male Urogenital Diseases

Interventions

• DRUG

No Results Yet

NCT04500548 | WITHDRAWN | PHASE1

0 participants

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-10

Start Date:

2021-05-11

Completion:

2022-06-21

Conditions

• Constitutional Mismatch Repair Deficiency Syndrome
• Hematopoietic and Lymphoid Cell Neoplasm
• Lynch Syndrome
• Recurrent Lymphoma
• Recurrent Malignant Solid Neoplasm
• Recurrent Neuroblastoma
• Recurrent Primary Central Nervous System Neoplasm
• Refractory Lymphoma
• Refractory Malignant Solid Neoplasm
• Refractory Neuroblastoma
• Refractory Primary Central Nervous System Neoplasm
• Xeroderma Pigmentosum

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet