Clinical Trials

NCT05784012 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

34 participants

Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-11-13

Completion:

2027-03-31

Conditions

• Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT05783297 | COMPLETED | NA

210 participants

Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-04-17

Completion:

2025-08-01

Conditions

• HIV Infections

Interventions

• BEHAVIORAL

No Results Yet

NCT05777031 | ACTIVE_NOT_RECRUITING | PHASE4

12 participants

Safety and Efficacy of Collagenase Clostridium Histolyticum After Prior Intralesional PRP for Peyronie's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-10-02

Completion:

2027-01-15

Conditions

• Peyronie Disease
• Sexual Dysfunctions, Psychological
• Genital Diseases, Male

Interventions

• DRUG

No Results Yet

NCT05751798 | RECRUITING | PHASE1/PHASE2

41 participants

Dose-finding and Dose Expansion Study of OSE-279 in Subjects With Advanced Solid Tumors or Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-12-20

Completion:

2029-12-31

Conditions

• Solid Advanced Tumor
• Lymphoma
• NSCLC (Non-small Cell Lung Cancer)

Interventions

• DRUG

No Results Yet

NCT05748730 | RECRUITING | NA

900 participants

Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-01-26

Completion:

2027-04-30

Conditions

• Suicide and Depression
• Adolescent Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT05741164 | RECRUITING | PHASE2

37 participants

Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2024-09-01

Completion:

2028-06-30

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Metastatic Triple-Negative Breast Carcinoma
• Refractory Triple-Negative Breast Carcinoma
• Unresectable Triple-Negative Breast Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG
• OTHER

No Results Yet

NCT05735639 | RECRUITING | PHASE4

3175 participants

THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2024-01-22

Completion:

2027-06-30

Conditions

• Venous Thromboembolism
• Varicose Veins

Interventions

• DRUG

No Results Yet

NCT05727267 | COMPLETED | PHASE1

26 participants

A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2024-01-23

Completion:

2026-05-21

Conditions

• Chronic Hepatitis B

Interventions

• BIOLOGICAL

No Results Yet

NCT05726487 | ACTIVE_NOT_RECRUITING | NA

224 participants

Physical Activity Intervention for Black Women With Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-05-04

Completion:

2026-05-08

Conditions

• Asthma

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05706116 | RECRUITING | PHASE1

18 participants

Controlled Human Infection Study of Orally Administered Trichuris Trichiura Eggs in Naïve Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2025-09-10

Completion:

2027-10-23

Conditions

• Whipworm
• Trichuriasis
• Controlled Human Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT05695976 | SUSPENDED

100 participants

GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-04

Start Date:

2023-04-18

Completion:

2029-01-31

Conditions

• Glioblastoma
• Glioma, Malignant

No Results Yet

NCT05688436 | ACTIVE_NOT_RECRUITING

1178 participants

A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babies

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-04

Start Date:

2021-09-24

Completion:

2031-01-17

Conditions

• Multiple Sclerosis

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05686317 | ACTIVE_NOT_RECRUITING | NA

100 participants

ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-04-01

Completion:

2026-11-01

Conditions

• Heart Failure

Interventions

• DEVICE
• DIAGNOSTIC_TEST

No Results Yet

NCT05660083 | RECRUITING | PHASE2

36 participants

Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-01-12

Completion:

2026-12-01

Conditions

• HER2-negative Breast Cancer
• Metastatic Breast Cancer
• Metaplastic Breast Carcinoma
• TNBC - Triple-Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05651178 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

10 participants

Human CD19-CD22 Targeted T Cells Injection for Refractory/Relapsed Central Nervous System Leukemia/Lymphoma Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-08-12

Completion:

2024-11-30

Conditions

• Central Nervous System Lymphoma

Interventions

• DRUG

No Results Yet

NCT05643534 | ACTIVE_NOT_RECRUITING | PHASE3

180 participants

Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-11-15

Completion:

2026-09-01

Conditions

• Irritable Bowel Syndrome With Constipation (IBS-C)

Interventions

• DRUG

No Results Yet

NCT05629377 | ACTIVE_NOT_RECRUITING

90 participants

Hypothalamic Amenorrhea as a Fertility Status Marker for Cardiovascular Health (ARCH)

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-04

Start Date:

2023-01-17

Completion:

2026-12-01

Conditions

• Hypothalamic Amenorrhea

No Results Yet

NCT05612178 | ACTIVE_NOT_RECRUITING | PHASE1

105 participants

A Study to Evaluate the Safety and Effects of Repeated Doses of 3BNC117-LS and 10-1074-LS on Persistent Viral Reservoirs in People Living With HIV and on Suppressive Antiretroviral Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-07-26

Completion:

2027-03-31

Conditions

• HIV-1

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT05575492 | COMPLETED | PHASE1/PHASE2

873 participants

A Study of mRNA-1647 Cytomegalovirus Vaccine in Healthy Participants 9 to 15 Years of Age and Participants 16 to 25 Years of Age

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-11-07

Completion:

2026-05-12

Conditions

• Cytomegalovirus

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT05535764 | RECRUITING | PHASE1

18 participants

AlloHCT With PegINFa for Myelofibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-08-02

Completion:

2026-08-31

Conditions

• Myelofibrosis

Interventions

• DRUG

No Results Yet

NCT05520866 | COMPLETED | NA

132 participants

PrehabPal: A Digital Tool to Help Older Adults Prepare for Cancer Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-03-14

Completion:

2026-05-31

Conditions

• Colon Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05516537 | COMPLETED | NA

121 participants

Examining the Effects of a Remotely-delivered, Racially-tailored Exercise Training Program for Immediate and Sustained Improvements in Walking Dysfunction, Symptoms, and Health-related Quality of Life (HRQOL) Among African-Americans With Multiple Sclerosis (MS) Residing in Rural Environments.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-09-02

Completion:

2025-12-31

Conditions

• Multiple Sclerosis

Interventions

• BEHAVIORAL

No Results Yet

NCT05502861 | COMPLETED | NA

18884 participants

A Pragmatic Trial of an Active Choice Nudge for Generalist or Specialist Palliative Care for Seriously Ill Inpatients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-11-13

Completion:

2026-05-17

Conditions

• Palliative Care

Interventions

• BEHAVIORAL

No Results Yet

NCT05499897 | COMPLETED | NA

34 participants

Interscalene Brachial Plexus Block and Early Wound-Related Symptoms After Open Rotator Cuff Repair

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-02-03

Completion:

2024-10-17

Conditions

• Rotator Cuff Tear
• Shoulder Surgery
• Postoperative Recovery

Interventions

• PROCEDURE

No Results Yet

NCT05489523 | ACTIVE_NOT_RECRUITING | PHASE4

25 participants

Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-05-01

Completion:

2027-05-31

Conditions

• Transthyretin Cardiac Amyloidosis

Interventions

• DRUG

No Results Yet

NCT05486559 | COMPLETED | NA

225 participants

The ECMO-Free Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-09-07

Completion:

2026-04-18

Conditions

• Extracorporeal Membrane Oxygenation Complication

Interventions

• OTHER

No Results Yet

NCT05481450 | COMPLETED | NA

131 participants

Efficacy and Safety Safety of Nutritears® in Adults With Dry Eye Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-08-15

Completion:

2023-05-15

Conditions

• Dry Eye
• Dry Eye Syndromes

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05477524 | COMPLETED | PHASE3

12546 participants

An Efficacy, Safety, Tolerability, Immunogenicity, and Lot-Consistency Clinical Trial of a 6-Valent OspA-Based Lyme Disease Vaccine (VLA15)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-08-04

Completion:

2026-01-07

Conditions

• Lyme Disease

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT05467930 | ACTIVE_NOT_RECRUITING

1520 participants

CU-COMMITS: COVID-19 Care in Black and Latino Communities and Households. Clinical and Molecular Outcomes of SARS-CoV-2

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-04

Start Date:

2021-07-01

Completion:

2027-05-31

Conditions

• COVID-19
• SARS CoV 2 Infection

Interventions

• OTHER

No Results Yet

NCT05436535 | COMPLETED | PHASE4

433 participants

Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-11-21

Completion:

2025-04-07

Conditions

• Atopic Dermatitis

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT05424003 | RECRUITING | PHASE2

50 participants

Randomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2024-02-22

Completion:

2026-08-01

Conditions

• NAFLD

Interventions

• DRUG

No Results Yet

NCT05423340 | COMPLETED | NA

163 participants

Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-06-12

Completion:

2024-10-03

Conditions

• Electronic Cigarette Use

Interventions

• OTHER

Results Available

NCT05419479 | SUSPENDED | PHASE1/PHASE2

46 participants

Switch Maintenance in Pancreatic

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-11-30

Completion:

2026-05-17

Conditions

• Pancreatic Cancer
• Adenocarcinoma of the Pancreas
• Squamous Cell Carcinoma of Pancreas
• Adenosquamous Carcinoma of the Pancreas

Interventions

• DRUG

No Results Yet

NCT05415137 | COMPLETED | PHASE3

268 participants

Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-09-15

Completion:

2025-06-25

Conditions

• Pulmonary Sarcoidosis

Interventions

• DRUG

No Results Yet

NCT05408117 | RECRUITING | NA

34 participants

Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-10-01

Completion:

2027-08-29

Conditions

• Scar

Interventions

• DEVICE

No Results Yet

NCT05390515 | RECRUITING | PHASE4

10 participants

Psoriatic Immune Response to Tildrakizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-09-01

Completion:

2028-09-01

Conditions

• Psoriasis Vulgaris

Interventions

• DRUG

No Results Yet

NCT05384002 | COMPLETED

14000 participants

An AI Platform Integrating Imaging Data and Models, Supporting Precision Care Through Prostate Cancer's Continuum

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-04

Start Date:

2021-02-24

Completion:

2025-03-31

Conditions

• Prostate Cancer
• Prostate Cancer Metastatic
• Prostate Cancer Recurrent
• Prostate Cancer Aggressiveness

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05374499 | COMPLETED | PHASE4

85 participants

Double-Blinded Randomized Controlled Study Investigating the Efficacy of Exparel (Liposomal Bupivacaine) for Postoperative Pain Relief in Mandibular Third Molar Extractions

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-09-01

Completion:

2023-12-01

Conditions

• Post Operative Pain

Interventions

• DRUG

Results Available

NCT05370911 | ACTIVE_NOT_RECRUITING | PHASE1

28 participants

Effects of Repeated Psilocybin Dosing in OCD

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2023-07-20

Completion:

2026-02-17

Conditions

• Obsessive-Compulsive Disorder

Interventions

• DRUG

No Results Yet

NCT05348785 | COMPLETED | PHASE2

650 participants

A Study to Learn About the Safety of BIIB122 Tablets and Whether They Can Slow the Worsening of Early-Stage Parkinson's Disease in Adults Between the Ages of 30 and 80

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-04

Start Date:

2022-04-19

Completion:

2026-03-09

Conditions

• Parkinson Disease

Interventions

• DRUG

No Results Yet