Clinical Trials

NCT06988618 | RECRUITING

600 participants

Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-08-11
Completion:: 2027-11-30

Conditions

Prurigo Nodularis

No Results Yet

NCT06980948 | RECRUITING | PHASE1/PHASE2

27 participants

Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-12-04
Completion:: 2027-07-31

Conditions

Chronic Neuropathic Pain

Interventions

GENETIC
PROCEDURE

No Results Yet

NCT06980077 | RECRUITING | PHASE2

25 participants

Ivonescimab for the Treatment of Thymic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-07-15
Completion:: 2027-06-17

Conditions

Thymus Carcinoma

Interventions

PROCEDURE
BIOLOGICAL
OTHER

No Results Yet

NCT06980038 | RECRUITING | PHASE2

44 participants

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-05-27
Completion:: 2027-11-24

Conditions

Head and Neck Squamous Cell Carcinoma
Hypopharyngeal Squamous Cell Carcinoma
Laryngeal Squamous Cell Carcinoma
Nasal Cavity Squamous Cell Carcinoma
Oral Cavity Squamous Cell Carcinoma
Oropharyngeal Squamous Cell Carcinoma
Recurrent Head and Neck Squamous Cell Carcinoma
Recurrent Hypopharyngeal Squamous Cell Carcinoma
Recurrent Laryngeal Squamous Cell Carcinoma
Recurrent Nasal Cavity Squamous Cell Carcinoma
Recurrent Oral Cavity Squamous Cell Carcinoma
Recurrent Oropharyngeal Squamous Cell Carcinoma
Stage III Laryngeal Cancer AJCC v8
Stage III Lip and Oral Cavity Cancer AJCC v8
Stage III Nasopharyngeal Carcinoma AJCC v8
Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVA Laryngeal Cancer AJCC v8
Stage IVA Lip and Oral Cavity Cancer AJCC v8
Stage IVA Nasopharyngeal Carcinoma AJCC v8
Stage IVB Laryngeal Cancer AJCC v8
Stage IVB Lip and Oral Cavity Cancer AJCC v8

Interventions

BIOLOGICAL
PROCEDURE

No Results Yet

NCT06979336 | RECRUITING | PHASE2

224 participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-09-29
Completion:: 2027-08-25

Conditions

Ulcerative Colitis

Interventions

DRUG

No Results Yet

NCT06972446 | RECRUITING | PHASE2

180 participants

A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-06-20
Completion:: 2027-02-28

Conditions

Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT06972108 | NOT_YET_RECRUITING | PHASE2

20 participants

CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-09-01
Completion:: 2027-08-31

Conditions

Meconium Aspiration Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT06971939 | RECRUITING | PHASE4

285 participants

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-11-21
Completion:: 2032-01-15

Conditions

Macular Telangiectasia Type 2 (MacTel)

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06969690 | COMPLETED | NA

180 participants

Question-Order Effect Experiment to Measure HIV Stigma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-11-02
Completion:: 2024-12-31

Conditions

HIV

Interventions

OTHER

No Results Yet

NCT06969677 | COMPLETED | NA

1300 participants

Personalized Normative Feedback to Increase HIV Testing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-11-02
Completion:: 2024-12-31

Conditions

HIV Testing
HIV Stigma

Interventions

OTHER

No Results Yet

NCT06966700 | RECRUITING | PHASE3

2400 participants

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-06-30
Completion:: 2033-03-23

Conditions

Breast Neoplasms
Triple Negative Breast Neoplasms
HR Low-Positive/HER2-Negative Breast Neoplasms

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06960200 | RECRUITING | PHASE2

528 participants

Phototherapy for Non-responders to Oral Appliance Therapy for Obstructive Sleep Apnea

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2024-01-05
Completion:: 2030-12-31

Conditions

Obstructive Sleep Apnea

Interventions

DEVICE

No Results Yet

NCT06959511 | RECRUITING | PHASE2

45 participants

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-07-22
Completion:: 2028-03-01

Conditions

Neoadjuvant Treatment
Thyroid Cancer

Interventions

DRUG

No Results Yet

NCT06958315 | ACTIVE_NOT_RECRUITING

198 participants

Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-06-16
Completion:: 2027-05-01

Conditions

Atherosclerotic Vascular Disease
Heterozygous Familial Hypercholesterolemia

Interventions

OTHER

No Results Yet

NCT06956482 | RECRUITING | PHASE3

477 participants

PROlonged Corticosteroid Treatment or N-ACetylcysteine for Severe Alcoholic Hepatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-05-22
Completion:: 2026-08-31

Conditions

Alcoholic Hepatitis

Interventions

DRUG

No Results Yet

NCT06952504 | RECRUITING | PHASE3

1123 participants

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-05-22
Completion:: 2032-05-24

Conditions

Endometrial Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06948110 | RECRUITING

300 participants

Deciphering the Genetic Architecture of Autoimmune Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-06-04
Completion:: 2030-04-22

Conditions

Autoimmune Diseases

No Results Yet

NCT06948097 | NOT_YET_RECRUITING | PHASE1

30 participants

Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-06-04
Completion:: 2028-07-14

Conditions

Lung Transplantation

Interventions

DRUG

No Results Yet

NCT06940752 | ENROLLING_BY_INVITATION | NA

30 participants

VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) Catheters

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-06-04
Completion:: 2026-12-01

Conditions

Ventricular Arrhythmia

Interventions

DEVICE

No Results Yet

NCT06931717 | RECRUITING | PHASE3

390 participants

A Clinical Study to Assess the Efficacy of Adjuvant Immunotherapy With Cemiplimab in Patients With Surgically Removed Non-small Cell Lung Cancer Who Have Not Received Prior Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-01-12
Completion:: 2029-03-31

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06931691 | RECRUITING

80 participants

A Multi-center, Ambispective Cohort Study to Evaluate the Impact of Iptacopan for Adult Patients With PNH in China

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-06-10
Completion:: 2027-04-21

Conditions

Paroxysmal Nocturnal Hemoglobinuria

Interventions

DRUG

No Results Yet

NCT06926621 | ENROLLING_BY_INVITATION | PHASE2

44 participants

A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type I

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-04-28
Completion:: 2029-01-30

Conditions

Myotonic Dystrophy Type 1 (DM1)

Interventions

DRUG

No Results Yet

NCT06924320 | RECRUITING | PHASE1/PHASE2

381 participants

A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-03-06
Completion:: 2026-09-15

Conditions

Obesity and Obesity-related Medical Conditions

Interventions

DRUG
OTHER

No Results Yet

NCT06923202 | RECRUITING

160 participants

Study of Alloknesia in Atopic Dermatitis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-02-10
Completion:: 2027-02-10

Conditions

Atopic Dermatosis
Alloknesie

No Results Yet

NCT06922110 | ENROLLING_BY_INVITATION | PHASE3

460 participants

An Open-Label Study of Azetukalner in Major Depressive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-03-18
Completion:: 2027-01-31

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT06919783 | ACTIVE_NOT_RECRUITING | NA

10 participants

Adapting a Health at Every Size Intervention to Obstetric Care

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-07-01
Completion:: 2026-05-05

Conditions

Weight Stigma

Interventions

BEHAVIORAL

No Results Yet

NCT06918002 | RECRUITING | PHASE3

824 participants

Elranatamab/Lenalidomide Consolidation and/or Elranatamab Maintenance Versus Standard of Care After D-VRd Induction in Transplant-eligible NDMM Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-07-09
Completion:: 2036-05-31

Conditions

Multiple Myeloma, Newly Diagnosed

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06915220 | RECRUITING | NA

60 participants

ADAPT Micro-Randomized Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-05-20
Completion:: 2026-09-30

Conditions

Cardiovascular Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT06909565 | RECRUITING | PHASE4

6000 participants

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-07-23
Completion:: 2029-10-31

Conditions

Percutaneous Coronary Intervention
Peripheral Endovascular Intervention

Interventions

DRUG

No Results Yet

NCT06908083 | ENROLLING_BY_INVITATION | PHASE1

50 participants

Immunologic and Virologic Parameters During Analytical Treatment Interruption Following Combination bNAb Therapy During Suppressive ART

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-09-08
Completion:: 2028-06-30

Conditions

HIV

Interventions

OTHER

No Results Yet

NCT06907706 | RECRUITING | NA

164 participants

Active Living After Cancer: Implementation Within Be Well Acres Homes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-04-03
Completion:: 2028-04-30

Conditions

Cancer
Fatigue

Interventions

BEHAVIORAL

No Results Yet

NCT06907654 | NOT_YET_RECRUITING | NA

2000 participants

Couples' Affect in Relationships Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-06-30
Completion:: 2028-12-31

Conditions

Depression Disorders

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT06906003 | RECRUITING

22 participants

Visual Rehabilitation and Depression in Visually Impaired Patients With AMD

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2024-12-02
Completion:: 2026-12-02

Conditions

AMD - Age-Related Macular Degeneration
Anxiety
Depression Disorders

Interventions

OTHER

No Results Yet

NCT06904235 | RECRUITING | PHASE2

95 participants

Study With IV NEPA (Fosnetupitant/Palonosetron) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Paediatric Cancer Patients Undergoing Highly Emetogenic Chemotherapy (HEC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-07-07
Completion:: 2027-10-31

Conditions

Nausea and Vomiting Chemotherapy-Induced
Nausea Post Chemotherapy

Interventions

DRUG

No Results Yet

NCT06904066 | RECRUITING | PHASE1

86 participants

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-06-04
Completion:: 2029-04-30

Conditions

Malignancy, Hematologic
Neoplasms, Hematologic
Neoplasms, Hematopoietic
Blood Cancer
Hematological Neoplasms
Hematopoietic Malignancies
Dysmyelopoietic Syndromes
Hematopoetic Myelodysplasia
Myeloid Leukemia, Acute
Nonlymphoblastic Leukemia, Acute
Leukemia, Lymphocytic, Acute

Interventions

DRUG
BIOLOGICAL
DEVICE

No Results Yet

NCT06902480 | NOT_YET_RECRUITING | NA

24 participants

Dairy Choline Bioavailability

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-07-31
Completion:: 2027-04-30

Conditions

Post-menopausal Women
Post-menopausal Status

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06898814 | RECRUITING | PHASE4

210 participants

The Effects of Intravenous Iron on Mobility in Elderly Patients Following Hip Fracture Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-06-09
Completion:: 2027-06-01

Conditions

Hip Fracture
Anemia

Interventions

DRUG

No Results Yet

NCT06892743 | RECRUITING | NA

56 participants

Analgesic Efficacy of Ultrasound-guided External Oblique Intercostal Plane Block Versus Posterior Transversus Abdominis Plane Block in Patients Undergoing Open Nephrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2025-04-01
Completion:: 2026-07-31

Conditions

Postoperative Pain

Interventions

PROCEDURE

No Results Yet

NCT06886776 | NOT_YET_RECRUITING | NA

666 participants

Implementing A Secure Firearm Storage Program in Illinois Health Centers in Partnership With AllianceChicago and the Illinois Primary Health Care Association (COMMUNITY ASPIRE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-07-01
Completion:: 2028-12-31

Conditions

Suicide

Interventions

BEHAVIORAL

No Results Yet

NCT06876142 | SUSPENDED | PHASE1/PHASE2

54 participants

Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2026-06-04
Completion:: 2033-01-01

Conditions

Multiple Myeloma
Relapsed and/or Refractory Multiple Myeloma (RRMM)

Interventions

DRUG

No Results Yet