Clinical Trials

NCT04707872 | RECRUITING

300 participants

Trifecta-Heart cfDNA-MMDx Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-06-01
Completion:: 2026-12-31

Conditions

Heart Transplant Rejection

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04695210 | COMPLETED | NA

149 participants

Virtual Peer-to-peer Support Programme for Carers of MND

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-06-07
Completion:: 2025-05-31

Conditions

Motor Neuron Disease
Amyotrophic Lateral Sclerosis

Interventions

BEHAVIORAL

No Results Yet

NCT04692818 | RECRUITING | NA

125 participants

3D Ultrasound Breast Imaging

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-11-10
Completion:: 2026-12-31

Conditions

Breast Tumor

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04676854 | ACTIVE_NOT_RECRUITING | NA

38 participants

Restoration of Central Vision With the PRIMA System in Patients With Atrophic AMD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-11-24
Completion:: 2024-02-01

Conditions

Geographic Atrophy

Interventions

DEVICE

No Results Yet

NCT04663724 | RECRUITING | NA

80 participants

Computer - Based Treatment for Social Anxiety Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-02-15
Completion:: 2026-11-30

Conditions

Social Anxiety Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT04662190 | COMPLETED | NA

12 participants

Evaluation of the Efficacy and Safety of 3D Printing for Orbital Surgery.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-07-05
Completion:: 2026-03-30

Conditions

Thyroid Associated Ophthalmopathy
Surgical Procedure, Unspecified

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT04646226 | ACTIVE_NOT_RECRUITING | NA

103 participants

The Arteriovenous Vascular (AV) ACCESS Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-08-18
Completion:: 2027-06-30

Conditions

End-Stage Kidney Disease
Hemodialysis Complication

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT04645160 | RECRUITING | PHASE1/PHASE2

31 participants

Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-03-04
Completion:: 2028-12-31

Conditions

Cholangiocarcinoma
Bile Duct Neoplasm
Biliary Tract Malignancy

Interventions

DRUG

No Results Yet

NCT04642053 | ACTIVE_NOT_RECRUITING | NA

72 participants

A Randomized Control Trial of Motor-based Intervention for CAS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-09-14
Completion:: 2026-08-31

Conditions

Childhood Apraxia of Speech

Interventions

BEHAVIORAL

No Results Yet

NCT04636684 | RECRUITING | NA

100 participants

Prevalence and Significance of ATTR Aortic Valve Amyloidosis in Degenerative Aortic Stenosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-12-01
Completion:: 2027-12-31

Conditions

Amyloidosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04635176 | TERMINATED | PHASE4

10 participants

Comparing Local Anesthesia With and Without iPACK Block

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-10-30
Completion:: 2026-05-27

Conditions

Osteo Arthritis Knee
Analgesia
Pain, Postoperative

Interventions

DRUG

No Results Yet

NCT04628767 | RECRUITING | PHASE2/PHASE3

131 participants

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-11-12
Completion:: 2027-09-30

Conditions

Renal Pelvis and Ureter Urothelial Carcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT04609072 | RECRUITING

200000 participants

Connect for Cancer Prevention Study (Connect)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-07-26
Completion:: 2070-12-31

Conditions

Cancer
General Research Use

No Results Yet

NCT04600804 | COMPLETED

200 participants

The Role of 18F-FDG-PET for Staging and Prognostication

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-10-30
Completion:: 2023-10-26

Conditions

Mantle Cell Lymphoma

No Results Yet

NCT04595760 | ACTIVE_NOT_RECRUITING

231 participants

Factors Influencing Fertility or Pregnancy Health

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-10-19
Completion:: 2030-12-31

Conditions

Menstrual Cycles
Conception
Early Pregnancy Loss
Pregnancy Outcomes

No Results Yet

NCT04594772 | ACTIVE_NOT_RECRUITING | PHASE2

32 participants

Adaptive Approach to Neoadjuvant Therapy to Maximize Resection Rates for Pancreatic Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-03-17
Completion:: 2025-06-13

Conditions

Pancreas Cancer

Interventions

DRUG
RADIATION
PROCEDURE

No Results Yet

NCT04590963 | ACTIVE_NOT_RECRUITING | PHASE3

370 participants

Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-10-02
Completion:: 2022-05-11

Conditions

Squamous Cell Carcinoma of the Head and Neck

Interventions

DRUG
OTHER

Results Available

NCT04575519 | TERMINATED | PHASE2

426 participants

Adjunctive Acetylsalicylic Acid and Ibuprofen for Tuberculosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-03-04
Completion:: 2023-12-19

Conditions

Tuberculosis, Pulmonary
Tuberculosis, MDR
Tuberculosis Infection

Interventions

DRUG

Results Available

NCT04573920 | ACTIVE_NOT_RECRUITING | PHASE2

103 participants

Atrasentan in Patients With Proteinuric Glomerular Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-03-15
Completion:: 2024-07-02

Conditions

IgA Nephropathy
Focal Segmental Glomerulosclerosis
Alport Syndrome
Diabetic Kidney Disease
Diabetic Nephropathy Type 2
Immunoglobulin A Nephropathy

Interventions

DRUG

No Results Yet

NCT04569175 | COMPLETED | NA

14 participants

Non Enhanced Labyrinth Imaging for the Detection of Endolymphatic Hydrops in Meniere's Disease "NELI Study"

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-11-06
Completion:: 2022-04-05

Conditions

Meniere Disease

Interventions

OTHER

No Results Yet

NCT04563078 | COMPLETED | NA

50 participants

Effect of TMS on PTSD Biomarkers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-02-15
Completion:: 2025-03-28

Conditions

Post Traumatic Stress Disorder

Interventions

DEVICE
PROCEDURE

Results Available

NCT04558593 | RECRUITING

330 participants

Surveillance of Complex Renal Cysts - The SOCRATIC Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-02-02
Completion:: 2029-12-20

Conditions

Complex Renal Cyst

Interventions

PROCEDURE

No Results Yet

NCT04557462 | ACTIVE_NOT_RECRUITING | PHASE3

448 participants

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-09-20
Completion:: 2030-12-04

Conditions

Primary IgA Nephropathy

Interventions

DRUG

No Results Yet

NCT04552288 | COMPLETED | PHASE2

51 participants

Study of Benralizumab in People With Skin Side Effects Caused by Cancer Therapies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-09-16
Completion:: 2024-07-19

Conditions

Solid Tumor
Solid Carcinoma
Solid Tumor, Adult
Hematologic Malignancy

Interventions

DRUG

Results Available

NCT04527549 | TERMINATED | PHASE2

5 participants

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-06-01
Completion:: 2024-01-08

Conditions

Clinical Stage IV Cutaneous Melanoma AJCC v8
Locally Advanced Melanoma
Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
Pathologic Stage IV Cutaneous Melanoma AJCC v8
Unresectable Melanoma

Interventions

DRUG

Results Available

NCT04519619 | RECRUITING

480 participants

Study to Learn More About Safety of Aflibercept Injection in Japanese Patients With Neovascular Glaucoma (NVG)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-11-27
Completion:: 2027-06-30

Conditions

Neovascular Glaucoma

Interventions

DRUG

No Results Yet

NCT04502758 | RECRUITING | NA

80 participants

Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2022-04-04
Completion:: 2027-12-31

Conditions

Suicidal Ideation
Major Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT04497259 | TERMINATED | NA

7 participants

Follow-up of Bariatric Surgery by Teleconsultations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-05-26
Completion:: 2024-07-22

Conditions

Obesity

Interventions

OTHER

No Results Yet

NCT04484220 | COMPLETED | NA

142 participants

Ellipsys Vascular Access System Post Market Surveillance (PS) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2021-04-13
Completion:: 2025-03-31

Conditions

Renal Disease, End Stage
Kidney Disease, End-Stage
AV Fistula
Fistulas Arteriovenous

Interventions

DEVICE

Results Available

NCT04466527 | TERMINATED | NA

4 participants

Laser Treatment of Moderate to Severe Acne Vulgaris

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-11-09
Completion:: 2022-07-27

Conditions

Acne Vulgaris

Interventions

DEVICE

Results Available

NCT04458922 | ACTIVE_NOT_RECRUITING | PHASE2

27 participants

Testing Atezolizumab in People 2-17 Years Old With Clear Cell Sarcoma or Advanced Chondrosarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-10-05
Completion:: 2022-11-28

Conditions

Central Chondrosarcoma, Grade 2
Central Chondrosarcoma, Grade 3
Dedifferentiated Chondrosarcoma
Metastatic Clear Cell Sarcoma of Soft Tissue
Metastatic Primary Central Chondrosarcoma
Unresectable Primary Central Chondrosarcoma

Interventions

DRUG
PROCEDURE

Results Available

NCT04453436 | ACTIVE_NOT_RECRUITING

2500 participants

HIV Drug Resistance Among Individuals Failing Tenofovir/Lamivudine and Dolutegravir First Line Regimen in Brazil

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2023-09-01
Completion:: 2024-12-31

Conditions

HIV
Drug
Resistance

Interventions

DRUG

No Results Yet

NCT04405986 | COMPLETED | NA

38 participants

Exploring Brain Damages After COVID-19 Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-05-19
Completion:: 2021-03-10

Conditions

SARS-CoV 2

Interventions

PROCEDURE

No Results Yet

NCT04377126 | COMPLETED | PHASE2

25 participants

Unacylated Ghrelin to Improve Functioning in PAD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-07-08
Completion:: 2025-01-23

Conditions

Peripheral Artery Disease

Interventions

DRUG

Results Available

NCT04365387 | COMPLETED | PHASE2

242 participants

A Study to Assess Immunization Responses in Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis Treated With Nemolizumab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-03-05
Completion:: 2023-07-07

Conditions

Dermatitis, Atopic

Interventions

DRUG

Results Available

NCT04365101 | TERMINATED | PHASE1/PHASE2

7 participants

Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-09-02
Completion:: 2021-08-30

Conditions

Coronavirus
Coronavirus Infection
Severe Acute Respiratory Syndrome Coronavirus 2
Pneumonia
Pneumonia, Viral
Lung Diseases
Respiratory Tract Disease
Respiratory Tract Infections
Coronaviridae Infections
Nidovirales Infections
RNA Virus Infections
Virus Disease
Immunologic Disease
ARDS
Immunologic Factors
Physiological Effects of Drugs
Antiviral Agents
Anti-infective Agents
Analgesics
Antimetabolites, Antineoplastic

Interventions

BIOLOGICAL

Results Available

NCT04349995 | COMPLETED

500 participants

Amplatzer PFO Occluder Post-marketing Surveillance Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-06-01
Start Date:: 2019-10-01
Completion:: 2022-12-14

Conditions

PFO - Patent Foramen Ovale

Interventions

DEVICE

No Results Yet

NCT04340843 | ACTIVE_NOT_RECRUITING | PHASE2

19 participants

Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-09-08
Completion:: 2024-02-22

Conditions

Locally Advanced Unresectable Primary Central Chondrosarcoma
Metastatic Primary Central Chondrosarcoma
Unresectable Primary Central Chondrosarcoma

Interventions

DRUG
PROCEDURE

Results Available

NCT04339738 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

Testing the Addition of Nivolumab to Chemotherapy in Treatment of Soft Tissue Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-11-04
Completion:: 2025-03-30

Conditions

Skin Angiosarcoma
Skin Radiation-Related Angiosarcoma
Visceral Angiosarcoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL
OTHER

Results Available

NCT04330833 | COMPLETED | NA

111 participants

Informational Meetings for Planning and Coordinating Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-06-01
Start Date:: 2020-12-08
Completion:: 2025-07-31

Conditions

End of Life
Communication
Cancer Metastatic

Interventions

OTHER

No Results Yet