Clinical Trials

NCT06458712 | RECRUITING | PHASE1

180 participants

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-11-21

Completion:

2028-08-31

Conditions

• Advanced Malignancies With Homologous Recombination Deficiency (HRD) (Breast, Ovarian, mCRPC, Pancreatic Ductal Adenocarcinoma (PDAC), Brain Metastases)

Interventions

• DRUG

No Results Yet

NCT06458439 | RECRUITING | PHASE2

31 participants

Epcoritamab-CAR T Cells for Large B-cell Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-09-24

Completion:

2027-10-31

Conditions

• Lymphoma, Non-Hodgkin
• Relapsed Diffuse Large B Cell Lymphoma
• Refractory Diffuse Large B-cell Lymphoma
• High-grade B-cell Lymphoma
• Transformed Indolent Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT06454630 | COMPLETED | PHASE2

179 participants

A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-06-27

Completion:

2024-11-19

Conditions

• Venous Thromboembolism

Interventions

• DRUG

Results Available

NCT06442527 | WITHDRAWN | NA

0 participants

Using Virtual Reality Before Transcranial Magnetic Stimulation for the Treatment of OCD

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2025-05-31

Completion:

2025-12-31

Conditions

• Obsessive-Compulsive Disorder

Interventions

• DEVICE

No Results Yet

NCT06439082 | RECRUITING | PHASE3

315 participants

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-10-24

Completion:

2029-03-23

Conditions

• Sickle Cell Disease

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06437964 | COMPLETED | NA

226 participants

Prophylactic Antibiotics in Endoscopic Secondary Prevention of Gastroesophageal Variceal Bleeding

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-05-25

Completion:

2026-01-15

Conditions

• Cirrhosis, Liver
• Hypertension, Portal
• Variceal Hemorrhage

Interventions

• OTHER
• DRUG

No Results Yet

NCT06436729 | COMPLETED | NA

51 participants

Impact of MINST With and Without Splinting in Periodontitis Patients With Mobile Anterior Teeth

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-06-01

Completion:

2025-11-30

Conditions

• Tooth Mobility
• Periodontitis

Interventions

• PROCEDURE

No Results Yet

NCT06427876 | RECRUITING

40 participants

Fasenra Pediatric Japan Post-Marketing Study(PMS)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2024-07-16

Completion:

2028-12-31

Conditions

• Bronchial Asthma

No Results Yet

NCT06419699 | ACTIVE_NOT_RECRUITING

120 participants

CPAx: Responsiveness and Minimal Clinically Important Difference

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2024-05-23

Completion:

2026-10-31

Conditions

• Muscle Weakness
• Critical Illness Myopathy
• Critical Illness Polyneuropathy
• Critical Illness Polyneuromyopathy
• Physical Inactivity

No Results Yet

NCT06410508 | COMPLETED | NA

33 participants

Evaluation of a Brief Intervention to Improve Engagement in Early Intervention Services for Psychosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-09-01

Completion:

2026-05-22

Conditions

• Psychotic Disorders
• Psychiatric Hospitalization
• Engagement, Patient

Interventions

• OTHER

No Results Yet

NCT06393920 | RECRUITING

1950 participants

PulseSelect™ PFA Global Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2024-07-23

Completion:

2026-07-01

Conditions

• Atrial Fibrillation

No Results Yet

NCT06378320 | COMPLETED | NA

20 participants

eHealth for Breastfeeding Support - the HOTSPOT Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-05-15

Completion:

2024-12-20

Conditions

• Breast Feeding

Interventions

• OTHER

No Results Yet

NCT06351540 | NOT_YET_RECRUITING | PHASE1

40 participants

Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2026-08-01

Completion:

2027-07-01

Conditions

• Cannabis Use
• Impaired Driving
• Cognitive Impairment

Interventions

• DRUG

No Results Yet

NCT06350383 | COMPLETED | NA

260 participants

Adapting a Low-cost Intimate Partner Violence and Mental Health Response Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-05-21

Completion:

2025-04-30

Conditions

• Violence, Domestic
• Psychological Distress

Interventions

• BEHAVIORAL

Results Available

NCT06347497 | COMPLETED | PHASE3

600 participants

Zonisamide Versus Topiramate in Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-04-01

Completion:

2026-04-01

Conditions

• Migraine

Interventions

• DRUG

No Results Yet

NCT06346392 | ACTIVE_NOT_RECRUITING | PHASE3

592 participants

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-03-04

Completion:

2026-06-15

Conditions

• Gastric Cancer
• Gastroesophageal Junction Cancer

Interventions

• DRUG

No Results Yet

NCT06335628 | RECRUITING | NA

38 participants

Volumetric Dimensional Changes After Surgical Pontic Site Development Procedures With Connective Tissue Graft or Collagen Matrix

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-08-28

Completion:

2027-04-30

Conditions

• Connective Tissue Graft
• Volume Collagen Matrix Xenograft

Interventions

• DEVICE

No Results Yet

NCT06332534 | RECRUITING | PHASE3

110 participants

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-08-08

Completion:

2027-06-30

Conditions

• Crohn's Disease

Interventions

• DRUG

No Results Yet

NCT06329453 | RECRUITING

100 participants

Intestinal Immunity in Neurologic Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2022-08-02

Completion:

2027-08-31

Conditions

• Multiple Sclerosis
• Parkinson Disease
• REM Sleep Behavior Disorder

Interventions

• PROCEDURE

No Results Yet

NCT06317649 | RECRUITING | PHASE2

147 participants

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-09-27

Completion:

2029-05-15

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT06311864 | COMPLETED

90 participants

Real-World Observational Study on Patient-Reported Outcomes in the Treatment of Insomnia With Daridorexant in Canada

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2024-06-20

Completion:

2026-05-19

Conditions

• Insomnia

Interventions

• DRUG

No Results Yet

NCT06311214 | RECRUITING | PHASE2

500 participants

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2025-03-18

Completion:

2028-03-31

Conditions

• Advanced Malignant Solid Neoplasm
• Metastatic Malignant Solid Neoplasm

Interventions

• PROCEDURE
• OTHER
• DRUG
• BIOLOGICAL

No Results Yet

NCT06303505 | RECRUITING | PHASE1/PHASE2

250 participants

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-06-12

Completion:

2027-12-31

Conditions

• Ovarian Cancer
• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT06266143 | COMPLETED | PHASE1/PHASE2

71 participants

A Trial of Y101D in Combination With Gemcitabine and Albumin Paclitaxel in Patients With Advanced Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2023-02-08

Completion:

2025-01-21

Conditions

• Advanced Pancreatic Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT06254326 | RECRUITING | PHASE1

12 participants

ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-09-19

Completion:

2027-12-31

Conditions

• Recurrent Oligodendroglioma
• Progressive Oligodendroglioma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06248411 | RECRUITING | PHASE1

189 participants

A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2023-11-01

Completion:

2029-10-31

Conditions

• Advanced or Metastatic Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06247995 | RECRUITING | PHASE1/PHASE2

58 participants

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-08-14

Completion:

2031-09-09

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06244628 | RECRUITING | PHASE3

20 participants

Safety and Efficacy of Iguratimod in the Treatment of Chronic GVHD

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-01-10

Completion:

2027-06-01

Conditions

• cGVHD

Interventions

• DRUG

No Results Yet

NCT06243835 | TERMINATED | PHASE1

16 participants

A Study to Test the Effects of Kindolor at Different Doses in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-04-21

Completion:

2024-11-22

Conditions

• Chronic Pain

Interventions

• DRUG

Results Available

NCT06241313 | ACTIVE_NOT_RECRUITING | PHASE3

1300 participants

Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-03-25

Completion:

2025-07-07

Conditions

• Migraine

Interventions

• DRUG

No Results Yet

NCT06240754 | RECRUITING | PHASE2

15 participants

Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-10-10

Completion:

2028-01-31

Conditions

• Clonal Cytopenia of Undetermined Significance
• CCUS Clonal Cytopenia of Undetermined Significance

Interventions

• DRUG

No Results Yet

NCT06227910 | RECRUITING | PHASE3

396 participants

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2025-01-02

Completion:

2027-06-08

Conditions

• Crohn's Disease

Interventions

• DRUG

No Results Yet

NCT06225596 | ACTIVE_NOT_RECRUITING | PHASE2

375 participants

Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-01-24

Completion:

2028-03-31

Conditions

• Metastatic Urothelial Cancer

Interventions

• DRUG

No Results Yet

NCT06210854 | NOT_YET_RECRUITING | PHASE2

48 participants

Assessing Administration of pBI-11 Via Electroporation for the Treatment of Patients With HPV16/18+

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2026-07-31

Completion:

2029-03-31

Conditions

• HPV Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT06207162 | RECRUITING | NA

10 participants

Longitudinal Neural Fingerprinting of Opioid-use Trajectories

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-10-10

Completion:

2027-01-31

Conditions

• Opioid Use Disorder

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06179290 | COMPLETED | NA

921 participants

Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2023-10-02

Completion:

2024-05-15

Conditions

• Tobacco Use

Interventions

• OTHER

Results Available

NCT06177171 | RECRUITING | PHASE1

18 participants

Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-02-07

Completion:

2028-01-31

Conditions

• BRCA1 Mutation
• BRCA2 Mutation
• BRCA Mutation
• PALB2 Gene Mutation
• Checkpoint Kinase 2 Gene Mutation
• ATM Gene Mutation

Interventions

• DRUG

No Results Yet

NCT06164808 | RECRUITING | NA

205 participants

Cardiac Arrhythmia Telemetry; Conventional vs HeartWatch

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-02-20

Completion:

2024-07-01

Conditions

• Cardiac Arrhythmia
• Diagnostic/Monitoring Devices Related to Adverse Incidents

Interventions

• DEVICE

No Results Yet

NCT06159673 | RECRUITING | PHASE2/PHASE3

1074 participants

ACP-204 in Adults With Alzheimer's Disease Psychosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2023-11-14

Completion:

2028-01-31

Conditions

• Alzheimer's Disease Psychosis

Interventions

• DRUG

No Results Yet

NCT06158841 | RECRUITING | PHASE3

380 participants

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2024-05-19

Completion:

2027-12-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet