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Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products

NCT06179290 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 921

Last updated 2025-05-04

No results posted yet for this study

Summary

The purpose of the study is to evaluate changes in biomarkers of exposure (BoE) to harmful and potentially harmful constituents (HPHCs) in adult smokers who completely switch to Ploom heated tobacco products (HTPs) compared to those who continue to smoke usual brand combustible cigarettes (UBCC).

Conditions

  • Tobacco Use

Interventions

OTHER

Ploom HTP Menthol HTS; MX3 (681)

Menthol heated tobacco product

OTHER

Ploom HTP Tobacco HTS; R8 (120)

Non-menthol heated tobacco product

OTHER

Smoking Abstinence (menthol)

No smoking or other tobacco product use for duration of the study, menthol group comparator

OTHER

Smoking Abstinence (non-menthol)

No smoking or other tobacco product use for duration of the study, non-menthol group comparator

Sponsors & Collaborators

  • Celerion

    collaborator INDUSTRY

  • Altria Client Services LLC

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
22 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-02
Primary Completion
2024-05-15
Completion
2025-03-24

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06179290 on ClinicalTrials.gov