Clinical Trials

NCT05226780 | TERMINATED | PHASE2

8 participants

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-07-12
Completion:: 2025-11-12

Conditions

SCN8A Developmental and Epileptic Encephalopathy Syndrome

Interventions

DRUG

No Results Yet

NCT05224102 | ACTIVE_NOT_RECRUITING | PHASE4

218 participants

A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-02-28
Completion:: 2027-01-26

Conditions

Diabetic Macular Edema

Interventions

DRUG

No Results Yet

NCT05216016 | COMPLETED | NA

3414 participants

Minnesota RETAIN Phase 2 (Sub-study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-12-23
Completion:: 2026-05-16

Conditions

Injuries Related Work
Illness Related Work
Disability

Interventions

OTHER

No Results Yet

NCT05202353 | RECRUITING | PHASE1

30 participants

A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2024-10-01
Completion:: 2026-12-02

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT05198830 | RECRUITING | PHASE2

42 participants

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-12-15
Completion:: 2027-06-30

Conditions

Lung Adenocarcinoma
Lung Large Cell Carcinoma
Lung Non-Squamous Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8

Interventions

DRUG
PROCEDURE
BIOLOGICAL
RADIATION

No Results Yet

NCT05197998 | SUSPENDED | NA

1200 participants

Promoting ColorBRAVE Conversations in Families

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2026-08-01
Completion:: 2027-05-31

Conditions

Child Development
Parents
Prosocial and Emotional Well-Being

Interventions

BEHAVIORAL

No Results Yet

NCT05197530 | RECRUITING | PHASE1

40 participants

Imaging of Lymphatic Vessels in People With Rheumatoid Arthritis (RA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-12-30
Completion:: 2026-06-30

Conditions

Rheumatoid Arthritis

Interventions

DRUG
DEVICE

No Results Yet

NCT05181462 | COMPLETED | PHASE1/PHASE2

117 participants

Nadunolimab in Combination With Gemcitabine Plus Carboplatin in Patients With Advanced Triple Negative Breast Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-01-11
Completion:: 2026-04-09

Conditions

Triple Negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT05176483 | RECRUITING | PHASE1

1314 participants

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-12-14
Completion:: 2030-06-28

Conditions

Renal Cell Carcinoma (RCC)
Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Urothelial Carcinoma (UC)
Solid Tumor
Hepatocellular Carcinoma (HCC)
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Head and Neck Squamous Cell Carcinoma (HNSCC)
Clear Cell Renal Cell Carcinoma (ccRCC)
Non-Clear Cell Renal Cell Carcinoma (nccRCC)

Interventions

DRUG

No Results Yet

NCT05147363 | WITHDRAWN

0 participants

Shockwave: Disruption for A Better Fit

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-27
Start Date:: 2020-12-07
Completion:: 2022-07-22

Conditions

Peripheral Arterial Disease

Interventions

DEVICE

No Results Yet

NCT05145426 | COMPLETED | NA

61 participants

Investigation of Low-intensity Focused Ultrasound for Human Pain Management

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-02-04
Completion:: 2025-07-23

Conditions

Chronic Pain

Interventions

DEVICE

No Results Yet

NCT05138263 | ACTIVE_NOT_RECRUITING

640 participants

Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer's disease2 (KBASE2)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-01-01
Completion:: 2027-09-30

Conditions

Alzheimer Disease
Mild Cognitive Impairment

No Results Yet

NCT05129696 | COMPLETED | NA

8150 participants

Integrating Early Stimulation and Play at Scale: "MAHAY Mikolo"

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-02-01
Completion:: 2025-03-31

Conditions

Early Childhood Development

Interventions

BEHAVIORAL

No Results Yet

NCT05112926 | ACTIVE_NOT_RECRUITING | NA

9 participants

Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-12-08
Completion:: 2026-07-31

Conditions

Knee Osteoarthritis

Interventions

DEVICE

No Results Yet

NCT05111574 | RECRUITING | PHASE2

101 participants

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-08-11
Completion:: 2026-09-01

Conditions

Anal Melanoma
Bladder Melanoma
Cervical Melanoma
Esophageal Melanoma
Gallbladder Melanoma
Head and Neck Mucosal Melanoma
Mucosal Melanoma
Nasopharyngeal Mucosal Melanoma
Oral Cavity Mucosal Melanoma
Penile Mucosal Melanoma
Rectal Melanoma
Recurrent Mucosal Melanoma
Sinonasal Mucosal Melanoma
Urethral Melanoma
Urinary System Mucosal Melanoma
Vaginal Melanoma
Vulvar Melanoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT05100862 | RECRUITING | PHASE3

780 participants

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-03-10
Completion:: 2028-07-31

Conditions

Relapsed/Refractory Follicular Lymphoma
Marginal Zone Lymphoma

Interventions

DRUG

No Results Yet

NCT05100056 | RECRUITING

70 participants

A Study of Brentuximab Vedotin in Adults With Hodgkin's Lymphoma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-03-08
Completion:: 2027-01-13

Conditions

Hodgkin Lymphoma

Interventions

OTHER

No Results Yet

NCT05088785 | ACTIVE_NOT_RECRUITING | NA

15 participants

Dynamic and Test-retest Whole Body [18F]FES PET Imaging in Patients With Metastatic ER+ Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-10-11
Completion:: 2026-12-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05084833 | COMPLETED | NA

300 participants

ASPIRES (Activating Cancer Survivors and Their Primary Care Providers to Increase Colorectal Cancer Screening) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-02-14
Completion:: 2025-09-30

Conditions

Colorectal Cancer
Early Detection of Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05076175 | RECRUITING | PHASE2/PHASE3

120 participants

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-05-30
Completion:: 2026-05-22

Conditions

Colitis, Ulcerative

Interventions

DRUG

No Results Yet

NCT05068102 | ACTIVE_NOT_RECRUITING | PHASE1

14 participants

A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-03-03
Completion:: 2026-09-16

Conditions

Carcinoma, Squamous Cell of Head and Neck (HNSCC)
Melanoma
Non-small Cell Lung Cancer (NSCLC)

Interventions

DRUG

No Results Yet

NCT05062915 | COMPLETED | NA

90 participants

Diagnostic Work up and Management of Acute Onset Vertigo

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-06-01
Completion:: 2024-12-31

Conditions

Acute Vestibular Syndrome
Vertigo

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05052801 | COMPLETED | PHASE3

547 participants

Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-03-07
Completion:: 2025-06-20

Conditions

Gastric Cancer
Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT05050240 | ACTIVE_NOT_RECRUITING | NA

20 participants

BATokines as Biomarkers of Brown Fat in Humans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-10-12
Completion:: 2026-12-31

Conditions

Healthy Lifestyle

Interventions

OTHER

No Results Yet

NCT05046821 | ACTIVE_NOT_RECRUITING

150 participants

Sporadic Inclusion Body Myositis Natural History Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-10-11
Completion:: 2027-03-31

Conditions

Sporadic Inclusion Body Myositis
Inclusion Body Myositis

No Results Yet

NCT05041361 | COMPLETED | NA

16 participants

HypErthermia as an Additional Treatment for the Biology and Experience of Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-10-11
Completion:: 2023-03-01

Conditions

Major Depressive Disorder

Interventions

BEHAVIORAL
DEVICE

Results Available

NCT05031507 | RECRUITING

100 participants

Study of Skeletal Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-01-18
Completion:: 2027-07-31

Conditions

Skeletal Disorders

No Results Yet

NCT05027958 | COMPLETED | EARLY_PHASE1

17 participants

Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-05-03
Completion:: 2024-11-07

Conditions

Healthy
Latent Tuberculosis Infection (LTBI)

Interventions

DRUG

Results Available

NCT05015608 | COMPLETED | PHASE3

216 participants

Study on Savolitinib Combined With Osimertinib in Treatment of Advanced NSCLC With MET Amplification

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-11-22
Completion:: 2025-08-22

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05006716 | RECRUITING | PHASE1/PHASE2

614 participants

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-09-13
Completion:: 2026-11-30

Conditions

B-cell Malignancy
Marginal Zone Lymphoma
Follicular Lymphoma
Non-Hodgkin Lymphoma
Waldenström Macroglobulinemia
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Mantle Cell Lymphoma
Diffuse Large B Cell Lymphoma

Interventions

DRUG

No Results Yet

NCT04992910 | COMPLETED | NA

16 participants

Multi-field Functional Electrical Stimulation for Distal Upper-limb Rehabilitation After Subacute Stroke: a Pilot Randomised Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-02-14
Completion:: 2023-08-01

Conditions

Stroke
Upper Extremity Paresis

Interventions

DEVICE
OTHER

No Results Yet

NCT04980495 | COMPLETED | PHASE3

69 participants

An Open-label Study to Investigate the Clinical Efficacy of Different Dosing Regimens of Efgartigimod IV in Patients With Generalized Myasthenia Gravis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-12-16
Completion:: 2023-08-24

Conditions

Generalized Myasthenia Gravis
MG - Myasthenia Gravis
gMG

Interventions

BIOLOGICAL

Results Available

NCT04975152 | RECRUITING | PHASE1

36 participants

Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-10-22
Completion:: 2028-03-31

Conditions

Merkel Cell Carcinoma
Cutaneous Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT04958239 | ACTIVE_NOT_RECRUITING | PHASE1

151 participants

A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-10-18
Completion:: 2026-04-27

Conditions

Neoplasms

Interventions

DRUG

No Results Yet

NCT04951219 | ACTIVE_NOT_RECRUITING | PHASE3

810 participants

A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-07-09
Completion:: 2027-03-31

Conditions

Non-Alcoholic Fatty Liver Disease

Interventions

DRUG

No Results Yet

NCT04886284 | RECRUITING | PHASE2

60 participants

Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2024-05-20
Completion:: 2027-04-30

Conditions

Staphylococcus Aureus Bacteremia
Staphylococcus Aureus Septicemia
Staphylococcal Sepsis
Staphylococcus Aureus Endocarditis

Interventions

DRUG

No Results Yet

NCT04862663 | RECRUITING | PHASE3

895 participants

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-05-10
Completion:: 2027-11-01

Conditions

Locally Advanced (Inoperable) or Metastatic Breast Cancer

Interventions

DRUG

No Results Yet

NCT04844827 | COMPLETED

143 participants

Pleural Carcinomatosis Tissue Banking

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-11-17
Completion:: 2024-12-02

Conditions

Pleural Effusion, Malignant

Interventions

GENETIC

No Results Yet

NCT04840602 | RECRUITING | PHASE2

92 participants

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2022-01-05
Completion:: 2028-03-31

Conditions

Lymphoplasmacytic Lymphoma
Waldenstrom Macroglobulinemia

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT04815967 | TERMINATED | PHASE2/PHASE3

32 participants

Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-27
Start Date:: 2021-11-02
Completion:: 2023-04-23

Conditions

Spasticity
Cerebrovascular Accident
Multiple Sclerosis
Traumatic Brain Injury
Cervical Spinal Cord Injury
Cerebral Palsy

Interventions

DRUG

Results Available