Clinical Trials

NCT04078386 | COMPLETED | PHASE2

42 participants

A Study of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Primary Sjögren's Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-11-21

Completion:

2021-06-23

Conditions

• Primary Sjögren's Syndrome

Interventions

• BIOLOGICAL

No Results Yet

NCT04070209 | ACTIVE_NOT_RECRUITING | PHASE2

66 participants

Management of Oligoprogressive Castration Resistant Prostate Cancer (PCS X)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2020-10-19

Completion:

2030-11-30

Conditions

• Metastatic Prostate Cancer
• Castration-resistant Prostate Cancer

Interventions

• DRUG
• RADIATION

No Results Yet

NCT03993158 | RECRUITING

10000 participants

Newborns From Patients Treated With ART (Assisted Reproductive Technology)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2010-01-01

Completion:

2050-12-31

Conditions

• Health Related

No Results Yet

NCT03969251 | COMPLETED | NA

14 participants

Transcranial Magnetic Stimulation (TMS) Treatment for Alcohol Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-07-11

Completion:

2021-02-10

Conditions

• Alcoholism

Interventions

• DEVICE

No Results Yet

NCT03969238 | COMPLETED

31 participants

Utilizing Helpline for Opioid Dependence Treatment

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2019-06-25

Completion:

2021-05-04

Conditions

• Opioid Dependence

Interventions

• BEHAVIORAL

No Results Yet

NCT03919071 | ACTIVE_NOT_RECRUITING | PHASE2

58 participants

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2020-02-20

Completion:

2027-09-30

Conditions

• Anaplastic Astrocytoma
• Anaplastic Astrocytoma, Not Otherwise Specified
• Anaplastic Ganglioglioma
• Anaplastic Pleomorphic Xanthoastrocytoma
• Glioblastoma
• Malignant Glioma
• WHO Grade 3 Glioma
• WHO Grade 4 Glioma

Interventions

• PROCEDURE
• DRUG
• RADIATION

No Results Yet

NCT03914625 | ACTIVE_NOT_RECRUITING | PHASE3

6720 participants

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-07-03

Completion:

2027-09-30

Conditions

• B Acute Lymphoblastic Leukemia
• B Lymphoblastic Lymphoma
• Down Syndrome

Interventions

• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT03899155 | RECRUITING | PHASE2

1500 participants

Pan Tumor Rollover Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-08-09

Completion:

2029-08-25

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT03881930 | RECRUITING | NA

40 participants

Balance Rehabilitation With Modified Visual Input in Patients With Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-10-01

Completion:

2027-06-01

Conditions

• Neuropathy
• Ataxia
• Proprioceptive Disorders
• Balance; Distorted

Interventions

• OTHER

No Results Yet

NCT03848052 | RECRUITING

75000 participants

Evolution of the Therapeutic Care in Lung Cancer in France Since 2015 (ESME LC)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2017-10-02

Completion:

2025-10-24

Conditions

• Lung Cancer

No Results Yet

NCT03802799 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

476 participants

Open Label Extension to Assess the Long-Term Safety and Tolerability of ZYN002 in Children and Adolescents With FXS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-11-09

Completion:

2026-06-30

Conditions

• Fragile X Syndrome

Interventions

• DRUG

No Results Yet

NCT03798678 | ACTIVE_NOT_RECRUITING | PHASE1

36 participants

CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-07-08

Completion:

2026-09-11

Conditions

• Recurrent Multiple Myeloma
• Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT03794583 | TERMINATED | PHASE3

41 participants

Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-12-21

Completion:

2022-11-29

Conditions

• Pulmonary Hypertension
• Chronic Obstructive Pulmonary Disease

Interventions

• DRUG

Results Available

NCT03783091 | COMPLETED | PHASE2

20 participants

A Trial of Vitamin B12 in Septic Shock

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-08-05

Completion:

2023-02-23

Conditions

• Septic Shock

Interventions

• DRUG

Results Available

NCT03771105 | RECRUITING | EARLY_PHASE1

30 participants

The Impact of Phosphate Metabolism on Healthy Aging

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-01-01

Completion:

2028-04-30

Conditions

• Hypophosphatemia
• Rickets
• Hypercalciuria
• XLH
• HHRH

Interventions

• DRUG

No Results Yet

NCT03765983 | TERMINATED | PHASE2

17 participants

GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-02-25

Completion:

2024-04-29

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT03760406 | COMPLETED | NA

22 participants

Optimization of VIM Targeting in Essential Tremor Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-03-18

Completion:

2023-08-29

Conditions

• Essential Tremor

Interventions

• PROCEDURE

No Results Yet

NCT03747627 | COMPLETED

475 participants

BPF Genetics of ILD Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2019-01-19

Completion:

2025-01-19

Conditions

• Lung; Disease, Interstitial, With Fibrosis
• Alveolitis, Extrinsic Allergic
• Bird Fancier's Lung
• Idiopathic Interstitial Pneumonias
• Lung Diseases, Interstitial
• Idiopathic Pulmonary Fibrosis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03741478 | ACTIVE_NOT_RECRUITING | PHASE1

64 participants

Intranasal Insulin and Olanzapine Study in Healthy Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-10-22

Completion:

2026-07-30

Conditions

• Healthy Controls

Interventions

• DRUG
• OTHER

No Results Yet

NCT03698994 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-11-14

Completion:

2022-03-31

Conditions

• Advanced Malignant Solid Neoplasm
• Recurrent Ependymal Tumor
• Recurrent Ewing Sarcoma
• Recurrent Glioma
• Recurrent Hepatoblastoma
• Recurrent Histiocytic and Dendritic Cell Neoplasm
• Recurrent Langerhans Cell Histiocytosis
• Recurrent Malignant Germ Cell Tumor
• Recurrent Malignant Solid Neoplasm
• Recurrent Medulloblastoma
• Recurrent Neuroblastoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Osteosarcoma
• Recurrent Peripheral Primitive Neuroectodermal Tumor
• Recurrent Primary Malignant Central Nervous System Neoplasm
• Recurrent Rhabdoid Tumor
• Recurrent Rhabdomyosarcoma
• Recurrent Soft Tissue Sarcoma
• Refractory Ependymoma
• Refractory Ewing Sarcoma
• Refractory Glioma
• Refractory Hepatoblastoma
• Refractory Histiocytic and Dendritic Cell Neoplasm
• Refractory Langerhans Cell Histiocytosis
• Refractory Malignant Germ Cell Tumor
• Refractory Malignant Solid Neoplasm
• Refractory Medulloblastoma
• Refractory Neuroblastoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Osteosarcoma
• Refractory Peripheral Primitive Neuroectodermal Tumor
• Refractory Primary Malignant Central Nervous System Neoplasm
• Refractory Rhabdoid Tumor
• Refractory Rhabdomyosarcoma
• Refractory Soft Tissue Sarcoma
• Wilms Tumor

Interventions

• OTHER
• DRUG

Results Available

NCT03695601 | ACTIVE_NOT_RECRUITING

2743 participants

Surveillance HeartCare® Outcomes Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2018-12-28

Completion:

2026-11-30

Conditions

• Heart Transplant Rejection

Interventions

• OTHER

No Results Yet

NCT03683251 | RECRUITING | PHASE3

1000 participants

Extension Study for the Port Delivery System With Ranibizumab (Portal)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-09-20

Completion:

2029-10-31

Conditions

• Neovascular Age-Related Macular Degeneration

Interventions

• DRUG

No Results Yet

NCT03654066 | ENROLLING_BY_INVITATION | PHASE4

50 participants

Botox or Botox With Esophageal Dilation in Patients With Achalasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-05-13

Completion:

2026-06-30

Conditions

• Achalasia

Interventions

• DRUG
• DEVICE
• OTHER
• DIAGNOSTIC_TEST

No Results Yet

NCT03650114 | ACTIVE_NOT_RECRUITING | PHASE3

1882 participants

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-12-28

Completion:

2028-09-30

Conditions

• Relapsing Multiple Sclerosis

Interventions

• BIOLOGICAL

No Results Yet

NCT03611595 | COMPLETED | PHASE1

15 participants

Cabozantinib in Combination With 13-cis-Retinoic Acid in Children With Relapsed or Refractory Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-08-28

Completion:

2026-02-24

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT03581292 | ACTIVE_NOT_RECRUITING | PHASE2

38 participants

Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-11-06

Completion:

2023-03-31

Conditions

• Anaplastic Astrocytoma
• Glioblastoma
• Malignant Glioma

Interventions

• RADIATION
• DRUG

Results Available

NCT03561649 | COMPLETED | NA

50 participants

Prediction of Treatment Response at 6 Months by Combinatorial Analysis of Serum Biomarkers in Biotherapy Naive SpA

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-06-14

Completion:

2019-12-14

Conditions

• Spondylitis, Ankylosing

Interventions

• DRUG

No Results Yet

NCT03433183 | COMPLETED | PHASE2

21 participants

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2019-10-02

Completion:

2022-06-22

Conditions

• Malignant Peripheral Nerve Sheath Tumors
• Neurofibromatosis 1

Interventions

• DRUG

Results Available

NCT03414151 | ACTIVE_NOT_RECRUITING

25 participants

Gut Microbiome in AP Naive

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2018-02-07

Completion:

2026-08-31

Conditions

• Psychotic Disorder
• Schizophrenia

Interventions

• OTHER

No Results Yet

NCT03392246 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-01-31

Completion:

2026-06-30

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT03388619 | COMPLETED | PHASE1

30 participants

Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-01-17

Completion:

2023-12-29

Conditions

• Cancer Of Prostate
• Prostate Neoplasms
• Prostate Cancer
• Neoplasms of Prostate
• Prostatic Cancer

Interventions

• RADIATION
• DIAGNOSTIC_TEST
• DRUG

Results Available

NCT03326206 | COMPLETED

28813 participants

Evaluating the Navajo Community Outreach and Patient Empowerment (COPE) Program

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2013-11-01

Completion:

2015-12-31

Conditions

• Diabetes Mellitus
• Metabolic Syndrome
• Hypertension
• Chronic Disease

Results Available

NCT03275311 | RECRUITING

42000 participants

Evolution of the Therapeutic Care in Metastatic Breast Cancer From 2008

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2014-07-31

Completion:

2027-03-31

Conditions

• Metastatic Breast Cancer

No Results Yet

NCT03275298 | SUSPENDED

13331 participants

Evolution of the Therapeutic Care in Ovarian Cancer From 2011

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-27

Start Date:

2017-04-01

Completion:

2025-12-31

Conditions

• Ovarian Cancer

No Results Yet

NCT03242343 | COMPLETED | NA

144 participants

VasQ External Support for Arteriovenous Fistula

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2017-11-29

Completion:

2020-10-08

Conditions

• Arterio-Venous Fistula
• ESRD
• Steal Syndrome
• Aneurysm
• Renal Failure
• Renal Disease
• Diabetes Mellitus
• Kidney Failure

Interventions

• DEVICE

Results Available

NCT03237377 | TERMINATED | PHASE2

9 participants

Neoadjuvant Immunoradiation for Resectable Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2017-12-12

Completion:

2021-11-04

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG
• RADIATION
• PROCEDURE

Results Available

NCT03213652 | ACTIVE_NOT_RECRUITING | PHASE2

13 participants

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-04-17

Completion:

2025-09-30

Conditions

• Advanced Malignant Solid Neoplasm
• Malignant Solid Neoplasm
• Recurrent Ependymoma
• Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
• Recurrent Hepatoblastoma
• Recurrent Langerhans Cell Histiocytosis
• Recurrent Malignant Germ Cell Tumor
• Recurrent Malignant Glioma
• Recurrent Malignant Solid Neoplasm
• Recurrent Medulloblastoma
• Recurrent Neuroblastoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Osteosarcoma
• Recurrent Primary Central Nervous System Neoplasm
• Recurrent Rhabdoid Tumor
• Recurrent Rhabdomyosarcoma
• Recurrent Soft Tissue Sarcoma
• Refractory Ependymoma
• Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
• Refractory Hepatoblastoma
• Refractory Langerhans Cell Histiocytosis
• Refractory Malignant Germ Cell Tumor
• Refractory Malignant Glioma
• Refractory Malignant Solid Neoplasm
• Refractory Medulloblastoma
• Refractory Neuroblastoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Osteosarcoma
• Refractory Primary Central Nervous System Neoplasm
• Refractory Rhabdoid Tumor
• Refractory Rhabdomyosarcoma
• Refractory Soft Tissue Sarcoma
• Wilms Tumor

Interventions

• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT03197818 | COMPLETED | PHASE3

708 participants

Active Controlled Trial of CHF5993 Pressurized Metered-dose Inhaler ( pMDI) vs Symbicort®Turbuhaler® in Patients With Chronic Obstructive Pulmonary Disease ( COPD) (TRIVERSYTI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2016-12-14

Completion:

2020-05-26

Conditions

• COPD (Chronic Obstructive Pulmonary Disease)

Interventions

• DRUG

Results Available

NCT03190915 | ACTIVE_NOT_RECRUITING | PHASE2

10 participants

Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2018-09-09

Completion:

2023-03-31

Conditions

• Juvenile Myelomonocytic Leukemia
• Neurofibromatosis Type 1

Interventions

• PROCEDURE
• DRUG

Results Available

NCT03180918 | RECRUITING | NA

100 participants

Male Fertility Preservation Using Cryopreservation of Testicular Tissue Before Highly Gonadotoxic Cancer Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-27

Start Date:

2015-01-31

Completion:

2100-01-31

Conditions

• Childhood Cancer
• Fertility Disorders

Interventions

• PROCEDURE

No Results Yet