Clinical Trials

NCT06437288 | ENROLLING_BY_INVITATION | PHASE4

198 participants

Hematoporphyrin Photodynamic Therapy for Esophageal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-09-18

Completion:

2027-09-30

Conditions

• Esophageal Cancer
• Photodynamic Therapy

Interventions

• PROCEDURE

No Results Yet

NCT06437054 | WITHDRAWN | PHASE1/PHASE2

0 participants

Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-12-15

Completion:

2026-12-15

Conditions

• Hearing Loss, Sensorineural
• Hearing Loss, Sudden
• Intratympanic Injection

Interventions

• DRUG
• OTHER

No Results Yet

NCT06431594 | RECRUITING | PHASE1

675 participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-07-02

Completion:

2027-09-22

Conditions

• Solid Tumors
• Neoplasms

Interventions

• DRUG

No Results Yet

NCT06431022 | COMPLETED | NA

70 participants

Web-administered STAIR for Patients on Behavioral Health Waitlists

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-11-15

Completion:

2026-05-10

Conditions

• Post Traumatic Stress Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT06430021 | RECRUITING

297 participants

Study of the Value of hPG80 (Circulating Progastrin) for the Diagnosis of Neuroendocrine Tumours in Patients With an MEN1 Mutation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2024-06-13

Completion:

2026-12-31

Conditions

• Neuroendocrine Tumors
• MEN1 Mutation

Interventions

• BIOLOGICAL

No Results Yet

NCT06429332 | RECRUITING | PHASE4

3500 participants

International Care Bundle Evaluation in Cerebral Hemorrhage Research

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-01-07

Completion:

2027-03-01

Conditions

• Intracerebral Hemorrhage
• Intracerebral Haemorrhage
• Intraventricular Hemorrhage
• Stroke
• Cerebrovascular Disease

Interventions

• OTHER
• DIAGNOSTIC_TEST

No Results Yet

NCT06425549 | RECRUITING | PHASE3

168 participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-06-25

Completion:

2028-08-21

Conditions

• Moderate to Severe Plaque Psoriasis

Interventions

• DRUG

No Results Yet

NCT06423430 | RECRUITING | NA

100 participants

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-09-11

Completion:

2027-04-30

Conditions

• Treatment Resistant Depression

Interventions

• DEVICE

No Results Yet

NCT06422143 | RECRUITING | PHASE3

851 participants

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-06-10

Completion:

2029-01-12

Conditions

• Non-small Cell Lung Cancer
• NSCLC

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06416969 | RECRUITING | EARLY_PHASE1

24 participants

Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-01-01

Completion:

2028-01-01

Conditions

• Obesity

Interventions

• DRUG

No Results Yet

NCT06415591 | RECRUITING | NA

240 participants

Auricular Neuromodulation in Veterans With Fibromyalgia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-11-01

Completion:

2028-09-01

Conditions

• Fibromyalgia

Interventions

• DEVICE

No Results Yet

NCT06413706 | ACTIVE_NOT_RECRUITING | PHASE2

45 participants

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-10-25

Completion:

2027-11-30

Conditions

• Glioma

Interventions

• DRUG

No Results Yet

NCT06393374 | RECRUITING | PHASE3

1530 participants

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-06-24

Completion:

2030-12-16

Conditions

• Triple-Negative Breast Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06391827 | COMPLETED | PHASE1

90 participants

A Study to Evaluate Safety, Tolerability, and PK of DA-7503 in Healthy Adult and Elderly Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-05-27

Completion:

2026-01-12

Conditions

• Healthy

Interventions

• DRUG

No Results Yet

NCT06389136 | RECRUITING | PHASE3

200 participants

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-06-14

Completion:

2026-08-31

Conditions

• Atopic Dermatitis

Interventions

• DRUG

No Results Yet

NCT06388785 | ACTIVE_NOT_RECRUITING

2000 participants

A Study to Monitor the Adverse Events of QDENGA Vaccine in Participants in Malaysia

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2024-09-26

Completion:

2027-05-08

Conditions

• Dengue Fever

Interventions

• OTHER

No Results Yet

NCT06388564 | ACTIVE_NOT_RECRUITING | PHASE2

130 participants

A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-10-11

Completion:

2027-06-01

Conditions

• Chronic Graft-versus-host-disease

Interventions

• DRUG

No Results Yet

NCT06387186 | COMPLETED | PHASE1

4 participants

Leucine Enriched Essential Amino Acid Powder as an Add-on to a Classic Ketogenic Diet in Refractory Epilepsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-05-10

Completion:

2026-02-18

Conditions

• Refractory Epilepsy
• Drug Resistant Epilepsy

Interventions

• DRUG

No Results Yet

NCT06386497 | RECRUITING | NA

15 participants

Acceptability of the Somnomat Casa for the Treatment of Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-01-11

Completion:

2027-12-31

Conditions

• Parkinson Disease

Interventions

• DEVICE

No Results Yet

NCT06386146 | RECRUITING | PHASE1/PHASE2

144 participants

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-07-24

Completion:

2027-01-31

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06382155 | RECRUITING | PHASE2

100 participants

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-10-21

Completion:

2026-06-30

Conditions

• Idiopathic Short Stature

Interventions

• DRUG

No Results Yet

NCT06381999 | COMPLETED

70 participants

Validity and Inter-rater Reliability for Early Recognition of Spasticity Using the Decision Tree Tool

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2023-10-27

Completion:

2024-02-26

Conditions

• Post-stroke Spasticity

No Results Yet

NCT06369298 | ACTIVE_NOT_RECRUITING | PHASE2

282 participants

Study of JK07 in Patients With Chronic Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-03-28

Completion:

2026-10-31

Conditions

• Heart Failure With Reduced Ejection Fraction
• Heart Failure With Preserved Ejection Fraction

Interventions

• DRUG

No Results Yet

NCT06367153 | COMPLETED | PHASE1

18 participants

A Study in Healthy Men and Women to Test Whether BI 1569912 Influences the Amount of Repaglinide, Midazolam and Bupropion in the Blood

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-05-15

Completion:

2024-08-20

Conditions

• Healthy

Interventions

• DRUG

Results Available

NCT06360536 | ACTIVE_NOT_RECRUITING | NA

37 participants

Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-03-19

Completion:

2026-10-01

Conditions

• Overweight or Obesity
• Prediabetes or Diabetes
• Prehypertension (Elevated Blood Pressure) or Hypertension
• Resistance Training

Interventions

• BEHAVIORAL

No Results Yet

NCT06351332 | TERMINATED | PHASE1/PHASE2

7 participants

ZAP-IT: ZN-c3 + Carboplatin + Pembrolizumab in mTNBC

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-05-01

Completion:

2026-02-24

Conditions

• Breast Cancer
• Breast Cancer Female
• Triple Negative Breast Cancer
• Hormone Receptor Negative Malignant Tumor Breast Triple
• HER2-negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06347796 | RECRUITING | NA

520 participants

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-11-01

Completion:

2029-02-28

Conditions

• Chronic Subdural Hematoma

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT06344819 | RECRUITING | PHASE2

78 participants

An Acupuncture Study for People At High Risk for Sepsis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-03-20

Completion:

2028-03-20

Conditions

• Sepsis

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT06340633 | RECRUITING | PHASE2

40 participants

SPI-1005 in Adults Receiving Cochlear Implant

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-12-31

Completion:

2026-12-31

Conditions

• Hearing Loss
• Cochlear Trauma

Interventions

• DRUG

No Results Yet

NCT06337838 | RECRUITING | PHASE3

100 participants

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-06-09

Completion:

2027-02-28

Conditions

• Chronic Kidney Diseases
• Acute Kidney Injury
• Bleeding
• Surgery

Interventions

• DRUG
• OTHER

No Results Yet

NCT06335082 | ENROLLING_BY_INVITATION

10000 participants

A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2024-04-24

Completion:

2026-11-30

Conditions

• Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT06326021 | RECRUITING | PHASE1

27 participants

Optimised CD33 (FL-33) CAR T Therapy for Refractory/Relapsed Acute Myeloid Leukaemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-04-02

Completion:

2026-06-15

Conditions

• Refractory/Relapsed Acute Myeloid Leukaemia

Interventions

• DRUG

No Results Yet

NCT06321211 | COMPLETED

30 participants

Development of a Novel Asian Mediterranean Diet and Its Acceptability in NAFLD

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2024-04-15

Completion:

2024-10-16

Conditions

• Fatty Liver, Nonalcoholic

No Results Yet

NCT06320054 | ACTIVE_NOT_RECRUITING | NA

69 participants

Preventing Obstetric Complications With Dietary Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-06-12

Completion:

2026-05-28

Conditions

• Gestational Diabetes
• Gestational Hypertension
• High Risk Pregnancy
• Preeclampsia

Interventions

• BEHAVIORAL

No Results Yet

NCT06319248 | RECRUITING | PHASE2

308 participants

MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-05-14

Completion:

2029-03-31

Conditions

• Sepsis
• Low Blood Pressure

Interventions

• DRUG
• OTHER

No Results Yet

NCT06317662 | RECRUITING | PHASE2

153 participants

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-06-05

Completion:

2028-12-31

Conditions

• Acute Leukemia of Ambiguous Lineage
• B Acute Lymphoblastic Leukemia

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT06316102 | COMPLETED | NA

124 participants

Promoting Viral Suppression Among Transgender Women Living With HIV in Santo Domingo

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2023-07-14

Completion:

2025-07-30

Conditions

• HIV

Interventions

• BEHAVIORAL

Results Available

NCT06314633 | COMPLETED | NA

149 participants

Socioeconomic Determinants of the Chemical Exposome and Its Genotoxic Effects in Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-01-29

Completion:

2025-07-31

Conditions

• Healthy Volunteer Children

Interventions

• OTHER

No Results Yet

NCT06312176 | RECRUITING | PHASE3

1200 participants

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-04-14

Completion:

2027-07-11

Conditions

• Breast Neoplasms

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT06312137 | RECRUITING | PHASE3

780 participants

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-04-03

Completion:

2034-02-21

Conditions

• Non Small Cell Lung Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet