Clinical Trials

NCT04634201 | TERMINATED | NA

3 participants

Effect of Probiotics on the Periodontal Status of Orthodontic Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2022-03-23

Completion:

2026-03-01

Conditions

• Periodontal Health
• Gingivitis

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04633239 | RECRUITING | PHASE1

42 participants

Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-07-02

Completion:

2026-11-01

Conditions

• Recurrent Ovarian High Grade Serous Adenocarcinoma
• Recurrent Platinum-Resistant Ovarian Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04629391 | RECRUITING | NA

296 participants

Anatomic TSA vs RTSA for Glenohumeral Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-09-01

Completion:

2027-05-01

Conditions

• Arthritis Shoulder

Interventions

• DEVICE

No Results Yet

NCT04628494 | ACTIVE_NOT_RECRUITING | PHASE3

483 participants

A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-01-13

Completion:

2025-10-13

Conditions

• Diffuse Large B-cell Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04619901 | TERMINATED

1 participants

Palliative Care in Maternity and Neonatology

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2020-02-12

Completion:

2023-08-31

Conditions

• Neonatal Critical Care

Interventions

• OTHER

No Results Yet

NCT04618653 | COMPLETED

192 participants

Comprehensive Process Model of AA-related Behavior Change

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2021-03-04

Completion:

2023-06-30

Conditions

• Alcohol Use Disorder (AUD)

Interventions

• OTHER

No Results Yet

NCT04611568 | ACTIVE_NOT_RECRUITING | NA

75000 participants

War on Melanoma™ Public Health & Education Campaign

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2019-05-14

Completion:

2026-12-30

Conditions

• Melanoma

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04602741 | COMPLETED | NA

91 participants

Examining a Digital Health Approach for Advancing Schizophrenia Illness Self-management and Provider Engagement

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-01-04

Completion:

2023-06-01

Conditions

• Schizophrenia
• Schizo Affective Disorder
• Psychotic Disorders

Interventions

• BEHAVIORAL

Results Available

NCT04595747 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-05-03

Completion:

2026-07-01

Conditions

• Locally Advanced Gastrointestinal Stromal Tumor
• Locally Advanced Sarcoma
• Metastatic Gastrointestinal Stromal Tumor
• Metastatic Sarcoma
• Stage III Gastric and Omental Gastrointestinal Stromal Tumor AJCC v8
• Stage III Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal Gastrointestinal Stromal Tumor AJCC v8
• Stage IV Gastric and Omental Gastrointestinal Stromal Tumor AJCC v8
• Stage IV Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal Gastrointestinal Stromal Tumor AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04595617 | COMPLETED | NA

28 participants

Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-01-06

Completion:

2023-07-06

Conditions

• Glanzmann Thrombasthenia

Interventions

• BIOLOGICAL

No Results Yet

NCT04591483 | RECRUITING

25 participants

Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2022-04-19

Completion:

2028-07-16

Conditions

• Stargardt-Like Macular Dystrophy

No Results Yet

NCT04589624 | RECRUITING | PHASE1

42 participants

An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-08-12

Completion:

2027-05-31

Conditions

• Thyroid Gland Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04577404 | COMPLETED | PHASE3

124 participants

Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-10-29

Completion:

2023-08-09

Conditions

• Amyotrophic Lateral Sclerosis (ALS)

Interventions

• DRUG

Results Available

NCT04572711 | COMPLETED

327 participants

Prospective Evaluation of Biliary Tissue Sampling With ERCP

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2020-10-01

Completion:

2024-12-18

Conditions

• Cholangiopancreatography, Endoscopic Retrograde
• Biliary Stricture
• Biliary Tract Diseases
• Cholangiocarcinoma

Results Available

NCT04570423 | RECRUITING | PHASE2

40 participants

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-05-20

Completion:

2027-10-31

Conditions

• Solid Tumors
• Lymphoma

Interventions

• DRUG

No Results Yet

NCT04569084 | TERMINATED | PHASE3

384 participants

Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-11-13

Completion:

2023-09-29

Conditions

• ALS

Interventions

• DRUG

Results Available

NCT04568148 | ACTIVE_NOT_RECRUITING

201 participants

COVID-19 Biorepository

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2020-04-15

Completion:

2023-12-31

Conditions

• Covid-19
• SARS-CoV 2
• Coronavirus
• COVID

No Results Yet

NCT04557631 | WITHDRAWN

0 participants

Evaluation of the Threshold for the Interpretation of the Results of a Method for the Blood Determination of Phosphatidyléthanol

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2021-09-01

Completion:

2021-11-01

Conditions

• Alcohol Abuse

No Results Yet

NCT04541108 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

15 participants

Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-07-26

Completion:

2031-12-31

Conditions

• Solid Tumor

Interventions

• BIOLOGICAL
• COMBINATION_PRODUCT

No Results Yet

NCT04534205 | RECRUITING | PHASE2/PHASE3

350 participants

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-01-07

Completion:

2029-04-30

Conditions

• Unresectable Head and Neck Squamous Cell Carcinoma
• Metastatic Head and Neck Cancer
• Recurrent Head and Neck Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT04530734 | RECRUITING

100 participants

Blood Concentration in Lorazepam and Treatment in Adult Catatonia

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2020-01-01

Completion:

2027-01-31

Conditions

• Catatonia

No Results Yet

NCT04524871 | RECRUITING | PHASE1/PHASE2

518 participants

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-11-01

Completion:

2027-07-30

Conditions

• Advanced Liver Cancers

Interventions

• DRUG

No Results Yet

NCT04522648 | ACTIVE_NOT_RECRUITING | NA

250 participants

Prospective Surveillance for Breast Cancer-Related Lymphedema

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-01-04

Completion:

2026-12-31

Conditions

• Breast Cancer

Interventions

• OTHER

No Results Yet

NCT04520087 | COMPLETED | NA

20 participants

Clinical and Radiographic Assessment After Surgical Treatment of Anterior Shoulder Dislocation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-10-13

Completion:

2026-05-04

Conditions

• Anterior Shoulder Dislocation
• Bone Defects
• Shoulder Instability

Interventions

• PROCEDURE

No Results Yet

NCT04503694 | ACTIVE_NOT_RECRUITING | PHASE2

72 participants

Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-03-25

Completion:

2026-12-31

Conditions

• Rectal Cancer Stage II
• Rectal Cancer Stage III

Interventions

• DRUG
• RADIATION
• PROCEDURE

No Results Yet

NCT04503395 | RECRUITING | NA

204 participants

ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-05-21

Completion:

2026-06-01

Conditions

• Aortic Aneurysm, Abdominal

Interventions

• DEVICE

No Results Yet

NCT04502186 | COMPLETED | NA

70 participants

A Systems-Level Intervention for Rural Adults With Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-09-20

Completion:

2023-07-31

Conditions

• Depressive Symptoms

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT04499248 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

100 participants

AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-11-16

Completion:

2029-04-30

Conditions

• Open-angle Glaucoma
• Ocular Hypertension

Interventions

• DRUG
• OTHER

No Results Yet

NCT04494009 | ACTIVE_NOT_RECRUITING | PHASE2

110 participants

PD-1 Inhibitor INCMGA00012 as Consolidation Therapy After Definitive Concurrent Chemoradiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-09-07

Completion:

2026-12-31

Conditions

• Esophageal Cancer

Interventions

• DRUG

No Results Yet

NCT04493164 | RECRUITING | PHASE2

30 participants

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-12-30

Completion:

2026-06-01

Conditions

• Acute Myeloid Leukemia With Gene Mutations
• Myelodysplastic Syndrome
• Myeloproliferative Neoplasm
• Recurrent Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT04489173 | COMPLETED | PHASE2

52 participants

TAS102 in Patients With ER-positive, HER2-negative Advanced Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-09-25

Completion:

2024-01-08

Conditions

• Breast Neoplasm
• Chemotherapy Effect

Interventions

• DRUG

No Results Yet

NCT04488757 | ACTIVE_NOT_RECRUITING | NA

70 participants

Neurobiological Mechanisms of Stress in Youth With Chronic Widespread Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-11-04

Completion:

2026-03-31

Conditions

• Chronic Widespread Pain
• Stress, Psychological
• Stress, Physiological

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT04484909 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

NBTXR3 Activated by Radiation Therapy for the Treatment of Locally Advanced or Borderline-Resectable Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-07-01

Completion:

2026-12-31

Conditions

• Borderline Resectable Pancreatic Adenocarcinoma
• Locally Advanced Pancreatic Ductal Adenocarcinoma
• Resectable Pancreatic Ductal Adenocarcinoma
• Stage III Pancreatic Cancer AJCC v8

Interventions

• OTHER
• RADIATION

No Results Yet

NCT04481789 | COMPLETED | PHASE1

84 participants

Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2018-10-17

Completion:

2018-12-20

Conditions

• Healthy Adult Subjects

Interventions

• DRUG

Results Available

NCT04481750 | COMPLETED | PHASE1

74 participants

Study of Oral Edaravone in Healthy Adult Males

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2018-03-20

Completion:

2018-08-03

Conditions

• Healthy Adult Subjects

Interventions

• DRUG

Results Available

NCT04466878 | COMPLETED

50 participants

Prognostic Value of Implementing VCE on Top in Constitutional VWD-patients With GI-bleeding

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2015-01-01

Completion:

2017-12-31

Conditions

• Von Willebrand Diseases

No Results Yet

NCT04465721 | COMPLETED | NA

57 participants

TREAT to Improve Cardiometabolic Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2021-06-14

Completion:

2026-04-01

Conditions

• Overweight and Obesity
• Prediabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT04452357 | ACTIVE_NOT_RECRUITING | NA

12 participants

Pulse-low-dose Rate (PLDR) Radiation in Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-01-13

Completion:

2026-12-01

Conditions

• Pancreatic Cancer

Interventions

• RADIATION

No Results Yet

NCT04449549 | RECRUITING | PHASE2

82 participants

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-08-24

Completion:

2027-04-02

Conditions

• Neoplasms

Interventions

• DRUG

No Results Yet

NCT04445090 | TERMINATED | PHASE1

68 participants

A Study in Healthy Men to Test How Well Different Doses of BI 1569912 Are Tolerated and How Food Influences the Amount of BI 1569912 in the Blood

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2020-07-21

Completion:

2021-09-10

Conditions

• Healthy

Interventions

• DRUG

Results Available